scholarly journals A Pioneering Physiotherapeutic Approach to the Treatment of a COVID Affected Patient – A Case Report

2021 ◽  
pp. 17-24
Author(s):  
Vaishnavi Siroya ◽  
Lynn Fernandes ◽  
Om C. Wadhokar
Keyword(s):  
Muscle Strength ◽  
Gait Training ◽  
Severe Form ◽  
Lower Limbs ◽  
Mechanical Ventilators ◽  
Severe Difficulty ◽  
To Come ◽  
And Function ◽  
Taste And Smell

The Coronavirus (SARS-CoV-19) originated from Wuhan, China and has affected globe since 2019. The virus spread to India in January, 2020. It is highly contagious. In its severe form, the victims of the virus suffered from symptoms such as breathing difficulties, fever, weakness, loss of taste and smell, amongst others. Patients were put on mechanical ventilators and as a result, the requirement of the role of cardio-respiratory physiotherapists became more and more essential. Even after weaning off from the ventilators and being detected Coronavirus negative, the role of the physiotherapists still remained indispensable in order to bring about improvement in the muscle strength of the affected weakened muscles, especially for patients whose movements were limited for extended periods of times due to being dependent on the ventilators; physiotherapists were also required to bring about improvement in the lung capacities and function, to teach gait training for those who find it difficult to walk, to improve in-coordination and overall allow the patients to come back to normal and carry out all the ADL independently and well. He had a severe difficulty in breathing and coughing, along with a generalized weakness all over his body, specifically both his lower limbs. He was admitted in the ICU immediately and was on mechanical ventilator. After all the physiotherapy sessions, the patient was able to carry out his activities of daily living independently; he regained his muscle strength and improved his coordination and ability to walk with a proper gait. He was also able to breathe independently with adequate respiratory muscle strength; and did not feel fatigued as quickly as he used to when he was detected positive for Coronavirus.

scholarly journals Robotic Technologies and Rehabilitation: New Tools for Stroke Patients’ Therapy

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Patrizia Poli ◽  
Giovanni Morone ◽  
Giulio Rosati ◽  
Stefano Masiero
Keyword(s):  
Gait Training ◽  
Lower Limbs ◽  
Robotic Rehabilitation ◽  
Stroke Patients ◽  
Home Based ◽  
Comprehensive Search ◽  
Improve Muscle Strength ◽  
Training Protocol ◽  
Robotic Technologies

Introduction. The role of robotics in poststroke patients’ rehabilitation has been investigated intensively. This paper presents the state-of-the-art and the possible future role of robotics in poststroke rehabilitation, for both upper and lower limbs.Materials and Methods. We performed a comprehensive search of PubMed, Cochrane, and PeDRO databases using as keywords “robot AND stroke AND rehabilitation.”Results and Discussion. In upper limb robotic rehabilitation, training seems to improve arm function in activities of daily living. In addition, electromechanical gait training after stroke seems to be effective. It is still unclear whether robot-assisted arm training may improve muscle strength, and which electromechanical gait-training device may be the most effective for walking training implementation.Conclusions. In the field of robotic technologies for stroke patients’ rehabilitation we identified currently relevant growing points and areas timely for developing research. Among the growing points there is the development of new easily transportable, wearable devices that could improve rehabilitation also after discharge, in an outpatient or home-based setting. For developing research, efforts are being made to establish the ideal type of treatment, the length and amount of training protocol, and the patient’s characteristics to be successfully enrolled to this treatment.

scholarly journals Self-Myofascial Release Intervention and Mobile App in Patients With Hemophilic Ankle Arthropathy: Protocol for a Randomized Controlled Trial (Preprint)

2019 ◽  
Author(s):  
Antonio Javier Meroño-Gallut ◽  
Rubén Cuesta-Barriuso ◽  
Raúl Pérez-Llanes ◽  
Elena Donoso-Úbeda ◽  
José-Antonio López-Pina
Keyword(s):  
Muscle Strength ◽  
Ankle Joint ◽  
Controlled Trial ◽  
Mobile App ◽  
Lower Limbs ◽  
Safety And Efficacy ◽  
Myofascial Release ◽  
Institutional Review ◽  
Patient Will ◽  
And Function

BACKGROUND Hemophilic ankle arthropathy is manifested by degenerative functional alterations and chronic pain. Myofascial release techniques are used to treat soft tissue adhesions, relieve pain, and reduce tissue sensitivity. OBJECTIVE This study aims to evaluate the safety and efficacy of a protocol using self-myofascial release with a foam roller to be applied in patients with hemophilic ankle arthropathy. METHODS Patients with ankle arthropathy (N=70) will be recruited, enrolled, and assigned to one of two groups—experimental or control—in a 1:1 allocation ratio. Patients will be recruited from 5 centers in different regions of Spain. Patient data will be collected at baseline, posttreatment, and follow-up. The primary outcome will be frequency of ankle joint bleeding (self-reported). The secondary outcomes will be ankle range of motion (measured with a digital goniometer); joint pain (measured with a visual analog scale and an algometer); joint status (measured using the Hemophilia Joint Health Score); muscle strength (measured with a dynamometer); functionality of lower limbs (measured using the 6-minute walking test); activity (self-reported); and muscle flexibility (measured using the fingertip-to-floor test). The treatment program includes 11 exercises that must be administered bilaterally. A mobile app will be developed where each patient will be able to observe the exercises to be carried out. Each session will last 15 minutes with 5 physiotherapy sessions per week for a period of 3 months. It is expected that patients with hemophilia who receive the foam roller intervention will show improvement in mobility, pain, and status of the ankle joint; muscle strength; and function in the lower extremities. RESULTS The study has been approved by the institutional review board of the University of Murcia. Patient recruitment will begin in September 2020, and the intervention period will last until June 2021. Data collection will take place between September 2020 and October 2021. CONCLUSIONS This protocol describes a randomized clinical trial to examine the safety and efficacy of a self-myofascial release intervention using a foam roller in patients with hemophilic ankle arthropathy. CLINICALTRIAL ClinicalTrials.gov NCT03914287; http://clinicaltrials.gov/ct2/show/NCT03914287. INTERNATIONAL REGISTERED REPORT PRR1-10.2196/15612

scholarly journals Self-Myofascial Release Intervention and Mobile App in Patients With Hemophilic Ankle Arthropathy: Protocol for a Randomized Controlled Trial

10.2196/15612 ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. e15612
Author(s):  
Antonio Javier Meroño-Gallut ◽  
Rubén Cuesta-Barriuso ◽  
Raúl Pérez-Llanes ◽  
Elena Donoso-Úbeda ◽  
José-Antonio López-Pina
Keyword(s):  
Muscle Strength ◽  
Ankle Joint ◽  
Controlled Trial ◽  
Mobile App ◽  
Lower Limbs ◽  
Safety And Efficacy ◽  
Myofascial Release ◽  
Institutional Review ◽  
Patient Will ◽  
And Function

Background Hemophilic ankle arthropathy is manifested by degenerative functional alterations and chronic pain. Myofascial release techniques are used to treat soft tissue adhesions, relieve pain, and reduce tissue sensitivity. Objective This study aims to evaluate the safety and efficacy of a protocol using self-myofascial release with a foam roller to be applied in patients with hemophilic ankle arthropathy. Methods Patients with ankle arthropathy (N=70) will be recruited, enrolled, and assigned to one of two groups—experimental or control—in a 1:1 allocation ratio. Patients will be recruited from 5 centers in different regions of Spain. Patient data will be collected at baseline, posttreatment, and follow-up. The primary outcome will be frequency of ankle joint bleeding (self-reported). The secondary outcomes will be ankle range of motion (measured with a digital goniometer); joint pain (measured with a visual analog scale and an algometer); joint status (measured using the Hemophilia Joint Health Score); muscle strength (measured with a dynamometer); functionality of lower limbs (measured using the 6-minute walking test); activity (self-reported); and muscle flexibility (measured using the fingertip-to-floor test). The treatment program includes 11 exercises that must be administered bilaterally. A mobile app will be developed where each patient will be able to observe the exercises to be carried out. Each session will last 15 minutes with 5 physiotherapy sessions per week for a period of 3 months. It is expected that patients with hemophilia who receive the foam roller intervention will show improvement in mobility, pain, and status of the ankle joint; muscle strength; and function in the lower extremities. Results The study has been approved by the institutional review board of the University of Murcia. Patient recruitment will begin in September 2020, and the intervention period will last until June 2021. Data collection will take place between September 2020 and October 2021. Conclusions This protocol describes a randomized clinical trial to examine the safety and efficacy of a self-myofascial release intervention using a foam roller in patients with hemophilic ankle arthropathy. Trial Registration ClinicalTrials.gov NCT03914287; http://clinicaltrials.gov/ct2/show/NCT03914287. International Registered Report Identifier (IRRID) PRR1-10.2196/15612

scholarly journals Pembinaan dan Penyuluhan terhadap Kader tentang Pengelolaan Posyandu Di Posyandu Cempaka Putih Desa Kolot Kelurahan Linggasari Kecamatan Ciamis

2019 ◽  
Vol 2 (2) ◽  
pp. 114-118
Author(s):  
Lusi Lestari ◽  
Lia Purwaningsih ◽  
Rike Mulyani
Keyword(s):  
Health Services ◽  
Health Information ◽  
Community Service ◽  
Healthy Life ◽  
Good Potential ◽  
The Government ◽  
To Come ◽  
And Function ◽  
Role And Function

IHC is one form of community-sourced health efforts (UKBM) managed from, by, for and with the community, to empower the community and provide facilities for the community to obtain basic health services. Efforts to improve the role and function of IHC are not merely the responsibility of the government, but all components in the community, including cadres. The role of cadres in the implementation of IHC is very large because in addition to being a provider of health information to the community to come to the IHC and carry out clean and healthy life behaviors. Linggasari is one of the villages in Ciamis Sub-District, Ciamis Regency, which has good potential about the existence of IHC. The number of IHC in Linggasari Village are 8 units. Cempaka Putih is one of the IHC in Linggasari Village. The IHC is still in progress, which requires assistance. Based on the situation, it is necessary to have assistance for the development of it by conducting community service, namely through fostering and counseling cadres on the management of IHC that is carried out from November 27, 2017 to January 03, 2018.

scholarly journals Sixth International Zooplankton Production Symposium: new challenges in a changing ocean

2017 ◽  
Vol 74 (7) ◽  
pp. 1839-1845
Author(s):  
Padmini Dalpadado ◽  
Astthor Gislason
Keyword(s):  
Marine Food Webs ◽  
Marine Zooplankton ◽  
Zooplankton Dynamics ◽  
To Come ◽  
Art Research ◽  
Monitoring Technologies ◽  
And Function ◽  
Global Platform ◽  
Zooplankton Production

Abstract The Sixth Zooplankton Production Symposium (ZPS) was organized to create an arena to discuss state of the art research on marine zooplankton. Eight sessions and seven workshops of broad scope were held at the conference to explore themes such as the role of zooplankton in marine food webs, response on production and biodiversity to climate change, use of new monitoring technologies, and the potential for zooplankton harvesting. It is the largest international symposium specifically devoted to research on zooplankton that has enabled participants to come together and disseminate findings from the world seas. The ZPS served as a global platform for international scientific collaboration to explore zooplankton dynamics, structure, and function in a changing ocean.

scholarly journals A INFLUÊNCIA DO EXCESSO DE PESO NA FORÇA MUSCULAR E NA FUNCIONALIDADE MULHERES JOVENS

2019 ◽  
Vol 8 (1) ◽  
pp. 250-262
Author(s):  
Pâmela Abreu Vargas Barbosa ◽  
Amanda Marques Faria ◽  
Daniella Alves Vento ◽  
Flávio Monteiro Ayres ◽  
Cibelle Kayenne Martins Roberto Formiga ◽  
...  
Keyword(s):  
Social Sciences ◽  
Muscle Strength ◽  
Young Women ◽  
Peak Torque ◽  
The Body ◽  
Lower Limbs ◽  
Cross Sectional ◽  
The Social ◽  
The Right ◽  
And Function

O objetivo foi verificar a influência do excesso de peso na força muscular e na funcionalidade de tronco de mulheres jovens. Estudo analítico transversal, com 54 mulheres de 18 a 30 anos, com excesso de peso (n=25), e eutróficas (n=29). A força muscular de tronco foi avaliada pelo dinamômetro isocinético e a funcionalidade de tronco e membros inferiores através do Bunkie Test. A análise dos dados foi realizada por meio do programa SPSS (Sciences Statistical Package for the Social Sciences). Como resultado, o presente estudo identificou que as mulheres com excesso de peso conseguem gerar pico de torque absoluto na 1º série (p=0,023), na 2º série (p=0,009), e no impulso na 2º série (p=0,009) maiores que as mulheres eutróficas. No entanto, quando o pico de torque foi analisado proporcionalmente ao peso corporal, estes valores foram menores, não sendo encontrada diferença entre os grupos (p0,05). Para o Bunkie Test, o grupo com excesso de peso apresentou pior desempenho na funcionalidade, principalmente nos movimentos de extensão, em decúbito dorsal, dos membros inferiores direito (p=0,011), esquerdo (p= 0,004) e na manutenção do tronco em decúbito lateral direito (p=0,008). Conclui-se que o excesso de peso pode alterar diretamente a força muscular e interferir na funcionalidade de tronco de mulheres jovens, sugerindo um desequilíbrio muscular em tronco e membros inferiores.Palavras-chave: Força Muscular. Obesidade. Funcionalidade. THE INFLUENCE OF OVERWEIGHT ON MUSCLE STRENGTH AND FUNCTION IN YOUNG WOMENABSTRACT: The aim of this study was to verify the influence of overweight on muscle strength and functionality in young women. This is a cross-sectional analytical study that was conducted with 54 women aged 18 and 30 years – twenty-five (25) were overweight and twenty-nine (29) were eutrophic. Muscle strength was assessed by an isokinetic dynamometer, whereas functionality was assessed by the Bunkie Test. Data analysis was performed using the SPSS program (Sciences Statistical Package for the Social Sciences). As a result, the present study identified that overweight women can generate absolute peak torque in the 1st grade (p = 0.023), in the 2nd grade (p = 0.009), and in the 2nd highest grade (p = 0.009) than eutrophic women. However, when the peak torque was analyzed proportionally to the body weight, these values were lower, and no difference was found between the groups (p 0.05). For the Bunkie Test, the overweight group presented worse performance in the functionality, especially in the extension movements, in the dorsal decubitus position, of the right lower limbs (p = 0.011), left (p = 0.004) and in the maintenance of the decubitus trunk right side (p = 0.008). It is concluded that overweight can directly affect muscle strength and interfere with the trunk function of young women, suggesting a muscle imbalance in the trunk and lower limbs.Keywords: Muscle Strength. Obesity. Functioning.

scholarly journals Role of KLHL3 and dietary K+ in regulating KS-WNK1 expression

2021 ◽  
Author(s):  
Mauricio Ostrosky-Frid ◽  
Maria Chavez-Canales ◽  
Jinwei Zhang ◽  
Olena Andrukova ◽  
Eduardo R. Argaiz ◽  
...  
Keyword(s):  
Amino Acid ◽  
Physiological Role ◽  
Kinase Domain ◽  
Severe Form ◽  
Missense Mutations ◽  
Amino Acid Residues ◽  
Specific Amino Acid ◽  
And Function ◽  
Familial Hyperkalemic Hypertension

The physiological role of the shorter isoform of WNK1 that is exclusively expressed in the kidney (KS-WNK1), with particular abundance in the distal convoluted tubule, remains elusive. KS-WNK1 despite lacking the kinase domain, is nevertheless capable of stimulating the NaCl cotransporter (NCC), apparently through activation of WNK4. It has recently been shown that a less severe form of the Familial Hyperkalemic Hypertension featuring only hyperkalemia is caused by missense mutations in the WNK1 acidic domain that preferentially affect CUL3-KLHL3 E3-induced degradation of KS-WNK1, rather than that of the full-length WNK1 (L-WNK1). Here we show that L-WNK1 is indeed less impacted by the CUL3-KLHL3 E3 ligase complex compared to KS-WNK1. We demonstrate that the unique 30 amino acid amino N-terminal fragment of KS-WNK1 is essential for its activating effect on NCC and recognition by KLHL3. We identify specific amino acid residues in this region critical for the functional effect of KS-WNK1 and KLHL3 sensitivity. To further explore this, we generated KLHL3-R528H knock-in mice that mimic human mutations causing Familial Hyperkalemic Hypertension. These mice revealed that the KLHL3 mutation specifically increased expression of KS-WNK1 in the kidney. We also observed that in wild type mice, expression of KS-WNK1 is only detectable after exposure to low potassium diet. These findings provide new insights into the regulation and function of KS-WNK1 by the CUL3-KLHL3 complex in DCT and indicate that this pathway is regulated by dietary K+ levels.

scholarly journals ‘If they weren’t in the Pub, they Probably wouldn’t Even Know each Other’: Alcohol, Sociability and Pub Based Leisure

2020 ◽  
Author(s):  
Thomas Thurnell-Read
Keyword(s):  
Social Interaction ◽  
Social Interactions ◽  
Social Role ◽  
Leisure Activities ◽  
Social Connections ◽  
Form And Function ◽  
The Social ◽  
To Come ◽  
And Function

Abstract While the form and function of pubs is diverse and has changed over time, there remains an at least notional consensus that the pub plays an important social function by providing a place for people to come together in pleasurable and meaningful social interaction. Drawing on qualitative research involving focus groups with pub goers and interviews with pub staff, this paper examines the forms of sociability that take place in UK pubs. Pubs are shown to be sites for varied social interactions which differ in form, intensity and meaning. This includes regular pub going rooted in customer routines but also occasional pub going linked to a wider range of events and associated leisure activities. A common theme across these forms of pub sociability is the value placed on feelings of social connections provided by different forms of social interaction and sociability which are facilitated by the hospitable atmospheres many pubs offer. Pubs are therefore cast as important sites through which various forms of sociability are enacted and enabled. The article contributes to ongoing debates about the social role of alcohol based leisure practises but also stresses the decentring of intoxication apparent in many of these accounts and, further, indicates an increasing diversification of pub based leisure.

Scanning electron microscopic study of collagen fibrillogenesis and extracellular compartmentalization in the chick embryo tendon

1986 ◽  
Vol 44 ◽  
pp. 208-209
Author(s):  
Grace C.H. Yang
Keyword(s):  
Chick Embryo ◽  
Extracellular Space ◽  
Fibroblast Cell ◽  
Collagen Fibrils ◽  
Electron Microscopic ◽  
Voltage Electron ◽  
Scanning Electron Microscopic Study ◽  
Microscopic Studies ◽  
And Function

The size and organization of collagen fibrils in the extracellular matrix is an important determinant of tissue structure and function. The synthesis and deposition of collagen involves multiple steps which begin within the cell and continue in the extracellular space. High-voltage electron microscopic studies of the chick embryo cornea and tendon suggested that the extracellular space is compartmentalized by the fibroblasts for the regulation of collagen fibril, bundle, and tissue specific macroaggregate formation. The purpose of this study is to gather direct evidence regarding the association of the fibroblast cell surface with newly formed collagen fibrils, and to define the role of the fibroblast in the control and the precise positioning of collagen fibrils, bundles, and macroaggregates during chick tendon development.

Role of the Cilia Membrane in Control of Microtubule Sliding

1980 ◽  
Vol 38 ◽  
pp. 612-615
Author(s):  
Edna S. Kaneshiro
Keyword(s):  
Control Mechanism ◽  
Beat Frequency ◽  
Surface Membrane ◽  
Ciliary Membrane ◽  
Ciliary Beating ◽  
Ciliary Reversal ◽  
Voltage Dependent ◽  
Reversal Mechanism ◽  
And Function

It is currently believed that ciliary beating results from microtubule sliding which is restricted in regions to cause bending. Cilia beat can be modified to bring about changes in beat frequency, cessation of beat and reversal in beat direction. In ciliated protozoans these modifications which determine swimming behavior have been shown to be related to intracellular (intraciliary) Ca2+ concentrations. The Ca2+ levels are in turn governed by the surface ciliary membrane which exhibits increased Ca2+ conductance (permeability) in response to depolarization. Mutants with altered behaviors have been isolated. Pawn mutants fail to exhibit reversal of the effective stroke of ciliary beat and therefore cannot swim backward. They lack the increased inward Ca2+ current in response to depolarizing stimuli. Both normal and pawn Paramecium made leaky to Ca2+ by Triton extrac¬tion of the surface membrane exhibit backward swimming only in reactivating solutions containing greater than IO-6 M Ca2+ Thus in pawns the ciliary reversal mechanism itself is left operational and only the control mechanism at the membrane is affected. The topographic location of voltage-dependent Ca2+ channels has been identified as a component of the ciliary mem¬brane since the inward Ca2+ conductance response is eliminated by deciliation and the return of the response occurs during cilia regeneration. Since the ciliary membrane has been impli¬cated in the control of Ca2+ levels in the cilium and therefore is the site of at least one kind of control of microtubule sliding, we have focused our attention on understanding the structure and function of the membrane.

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