scholarly journals A Study on Biomarkers in a Spatially Distributed Type – 2 Diabetes mellitus Groups in Southern Tamil Nadu, India

2017 ◽  
Vol 12 (01) ◽  
pp. 57-61
Author(s):  
Murugan. A
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Tamil Nadu ◽  
Spatially Distributed

scholarly journals Serum Ceruloplasmin levels in Type 2 Diabetes mellitus – Assessing the cardiovascular risk

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
S. Sakthi Indra ◽  
Dr. N. Sivaranjani ◽  
Dr. K. Rajalakshmi ◽  
Dr. S. Birundha ◽  
Dr. A. Balasubramanian
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cardiovascular Risk ◽  
Cardiovascular Diseases ◽  
Tamil Nadu ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Serum Ceruloplasmin

Type 2 diabetes mellitus is an endocrinological disease associated with hyperglycemia characterized by both insulin resistance and defective insulin secretion. Cardiovascular diseases are the peak reason for mortality in India, highest rate seen in Tamil Nadu state, from the age of 25 to 69 years. Many studies have revealed the importance of inflammatory pathway playing a pivotal role in the development and progression of diabetic complications. Ceruloplasmin, a copper containing mettalo-enzyme having antioxidant property (e.g ferroxidase activity) is an ideal marker to know the cardiovascular status, glycemic status, dyslipidemia and cancer risk. The purpose of the present study was to evaluate the effects of Body Mass Index (BMI) and Ceruloplasmin levels on the incidence of cardiovascular diseases in Type 2 Diabetes mellitus patients. Fasting Blood glucose, lipid profile which includes serum triglyceride, total cholesterol, LDL, VLDL, HDL and serum ceruloplasmin were investigated using fully automated chemistry analyzer. Diabetic patients were segregated into three groups based on their BMI, which was correlated with inflammatory marker ceruloplasmin to assess the cardiovascular risk. The mean value and standard deviation of ceruloplasminin controls (n=60) and diabetic cases divided into normal weight, over weight and obese (n=20 each) were 38.3±8.45, 36±7.99, 33.2±3.57and34.2±6.24 mg/dl respectively.  Ceruloplasmin among the cases and controls were not statistically significant. Serum ceruloplasmin levels and BMI showed no correlation among the group 1 diabetic cases and was not significant (p=0.29), among the group 2diabetic cases it showed weak correlation and was not significant (p=0.85), and it also showed no correlation among the group 3 diabetic cases and was not significant (p=0.65).This study revealed no significant association between serum ceruloplasmin level and BMI in all diabetic group subjects separately.

scholarly journals Awareness of diabetes among patients with type 2 diabetes mellitus attending a rural health and training center

2018 ◽  
Vol 5 (10) ◽  
pp. 4597
Author(s):  
V. Aljin ◽  
R. Umadevi ◽  
V. M. Anantha Eashwar
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Rural Health ◽  
Tamil Nadu ◽  
Steady Increase ◽  
Training Centre ◽  
Adequate Knowledge ◽  
And Training

Background: Diabetes mellitus (DM), a major threat to both developing and developed countries, which can be easily prevented by lifestyle modifications. Because of lack of awareness, the occurrence of diabetes and its complications is showing a steady increase. Empowering the patients with knowledge about diabetic self-care is expected to have better outcome of the disease. Thus this study was planned to assess the awareness and knowledge about diabetes among the patients with type 2 diabetes mellitus attending rural health care center. The objective of the study was to assess the awareness of diabetes among patients with type 2 diabetes mellitus attending a rural health and training centre (RHTC).Methods: A Cross sectional study was conducted to assess the awareness about diabetes among patients with type 2 diabetes, attending RHTC in Tamil Nadu. The study was conducted in outpatient clinic in RHTC, during the month of November and December 2017 and 258 patients with diabetes who gave written consent were included in the study. Data was collected using a pre-tested structured questionnaire through one-to-one interviews. Data entry and analysis was done using SPSS version 16.Results: It was found that, 63.1% of the participants had adequate knowledge regarding T2DM and family history of T2DM was one of the important determinant of having adequate knowledge regarding T2DM.Conclusions: Knowledge about diabetes is fair but still their practice on control of glycemic levels needs to be improved. This shows that there is a necessary to health educate the patients in order to prevent or postpone the complications of diabetes mellitus.  

scholarly journals Type 2 diabetes mellitus and its determinants among adults in an urban area of Kancheepuram district, Tamil Nadu

2018 ◽  
Vol 5 (5) ◽  
pp. 1956
Author(s):  
S. Gopalakrishnan ◽  
M. Muthulakshmi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Urban Area ◽  
Tamil Nadu ◽  
Adult Population ◽  
Overweight And Obesity ◽  
Cross Sectional ◽  
The Impact

Background: Type 2 diabetes mellitus (T2DM) is a modern day epidemic of epic proportions, affecting all strata of the society. The prevalence is becoming alarmingly high among younger age groups. The impact of this disease on physical, mental, social and economic wellbeing is huge and therefore warrants early detection and prevention. Aim of the study was to estimate the prevalence and determinants of T2DM among the adult population in an urban area.Methods: This cross sectional descriptive study was done in Anakaputhur, an urban area in Kancheepuram district. Based on 10.4% prevalence of T2DM, reported by the ICMR-INDIAB data (2011), the sample size was calculated to be 1680. Data was collected by convenient sampling method using a structured questionnaire from among the adult population. Fasting and postprandial plasma blood glucose was estimated. Data was analyzed using SPSS ver.16 software.Results: Mean age of the participants was 44.2 years. Females constituted 51.1% and 19.4% were known hypertensives, 10.9% were smokers and 55.3% were overweight/obese. The prevalence of T2DM was found to be 21.2%. Around 20% of affected individuals were belonging to <45 years of age. Overweight and obesity were significantly associated with occurrence of diabetes mellitus.Conclusions: This study has shown a high prevalence of Diabetes Mellitus. The associated determinants are found to be high and changing. This indicates that diabetes is resulting in an epidemiological and genetic transition of a disease of susceptibility. This necessitates the need for strategies for increasing the awareness, broad based screening, focused treatment and follow up.

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