Theoretical fabrication of subwavelength structures by surface plasmon interference based on complementary grating

This paper presents a surface plasmon interference lithography technique based on the complementary grating, which comprises silicon gratings and complementary aluminum grating masks, for fabricating subwavelength structures. In this theoretical study, the optimal parameters of the complementary grating structure were determined using the reflectance spectrum. The optical field distributions of one- and two-dimensional subwavelength structures were obtained using the finite-difference time-domain method and rotation-related formulas. The results of numerical evaluations show that a one-dimensional periodic structure with a half-pitch resolution of 60.5 nm (approximately [Formula: see text]/6.7) can be fabricated. In addition, subwavelength structures can be diversified using different rotation methods to expose the photolithography samples, such as square dot arrays and quasi-hexagonal closely packed structures. The proposed method combines surface plasmon interference with sample rotation, thereby enabling fabrication of abundant subwavelength structures.

Comparison of Clerkship Directors’ Expectations of Physical Examination Skills with Point-of-care Ultrasound Skills Using the RIME Framework

Background: The expectations of point-of-care ultrasound (PoCUS) in undergraduate clerkship at the University of Ottawa has not been described. We compared clerkship directors’ expectations of physical examination skills with PoCUS skills, before and after completing the clerkship rotation. Methods: A pilot-tested, expert developed, bilingual on-line survey consisting of 15 questions was sent to all clerkship directors (23) in December 2019. The survey included questions regarding the expectations of medical students with respect to physical examination and PoCUS using the RIME Framework: none, reporter, interpreter, manager, educator. Results: The response rate was 60.9% (14/23). With regards to physical exam skills, 82.8% of directors had no expectations or expected students to be reporters when starting clerkship. At graduation, 77.5% of directors expected students to be interpreters, managers, or educators. For PoCUS, 100.0% of directors had no expectations or expected students to be reporters when starting clerkship. At clerkship completion, 33.0% of directors felt that students should be interpreters or managers for PoCUS skills. Conclusions: Clerkship directors have low expectations of PoCUS skills for entering and graduating clerks when compared with their physical examination skills despite formal pre-clerkship PoCUS objectives. Enhanced communication and targeted education of directors could improve the PoCUS curriculum.

Mounting a smartphone on a steering-wheel to facilitate ease of visibility of the navigation screen: A systematic product design approach

BACKGROUND: Both professional and personal car drivers use smartphones as In-Vehicle Infotainment System (IVIS) and generally mount it wherever they feel convenient. Inappropriate or sub-optimal positioning of navigation devices increases off-road eye-glance duration and fixation frequency. OBJECTIVE: The current research aimed to develop a smartphone holding device to facilitate the mobile-phone’s easy mounting on the steering wheel’s hub, ensuring the screen’s visibility at a comfortable viewing angle in a vertical upright position irrespective of the steering wheel’s rotation. METHODS: A systematic product design methodology was adopted to develop the final product. The morphological chart was adopted for generating the different concepts of the smartphone mounting device. A Pugh chart was used for screening the various concepts generated in the previous step. Finally, a prototype of the selected best concept was made. User acceptance was assessed by taking feedback from users, and System Usability Scale (SUS) was used for usability evaluation. RESULTS: The developed innovative mounting device was light-weight and easy to use (SUS score 83.5). The final prototype was very effective in changing the angle of the smartphone to facilitate easy visibility at a comfortable viewing angle through the use of a ball and socket mechanism at the base. A ball bearing system was used in the mobile-phone holder for maintaining vertical stationary position during steering wheel rotation. CONCLUSION: As the device is useful for mounting the smartphone on the steering wheel’s hub, it might reduce driver distraction.

Evaluating the efficacy of self-study videos for the surgery clerkship rotation: an innovative project in undergraduate surgical education

Background: Educational videos have become valuable resources and can address some of the pitfalls of traditional learning. To ensure clerkship students have adequate exposure to curriculum objectives, a series of objective-aligned self-directed learning video podcasts covering core surgical concepts were developed by medical students and surgical residents. The objective of the study was to evaluate the efficacy of the video podcasts in the surgery clerkship rotation. Methods: Nineteen video podcasts were created, housed at www.surgicaleducationportal.com, and distributed to third-year medical students completing their surgical clerkship. A 10-question multiple-choice quiz was administered before and after students viewed each video, and they were also asked to complete a satisfaction survey. Results: A total of 302 paired pretests and posttests were completed. There was a mean increase of 2.7 points in posttest scores compared with pretest scores (p < 0.001). On a Likert scale from 1 to 5, with 5 being excellent, students rated the usefulness of the videos as 4.3, the quality of the content as 4.3 and the quality of the video as 4.2. Ninety-eight percent of students would recommend these videos to their classmates. Conclusion: Video podcasts are an effective modality for engaging medical students and may improve standardization of learning during their surgical clerkship.

The INSPIRE Support sub-scale: A critical view of the psychometric properties focusing on dimensionality

The statistical methods previously used for assessing dimensionality of the INSPIRE Support sub-scale are often not valid, which may lead to inaccurate conclusions. The first aim of this paper was to present and discuss the methods for assessing the dimensionality of the scale. The second aim was to illustrate these methods using data from a Norwegian translation of the INSPIRE Support sub-scale. Exploratory factor analysis with several extraction and rotation methods was used to identify the dimensionality of the scale. Cronbach’s alpha and omega coefficient were employed to assess the internal consistency. Using the recognized statistical approach, there was no clear structure found in the Support sub-scale, indicating that the scale might be one-dimensional. While single items or sum score of the INSPIRE Support sub-scale might cover important aspects of the personal recovery concept, there is no evidence of the five CHIME dimensions of this scale as published earlier. A more thorough assessment is called for, and results from studies using the five dimensions should be interpreted with caution.

Data mining Application of Data Reduction and Clustering Domain of Textile Database

This research paper attempts to identify the textile data structure and hidden pattern of original database with certain important parameters. The main objectives of this study are to identify the first n number of factors that explained over the study period. Initially factor analysis is performed to extract factor scores. Principal extraction is performed through Data mining package with sixteen textile fabrics parameters. Factor extraction is aimed to uncover the intrinsic pattern among the textile parameters considered and an important point of factor analysis is to extract factor scores for further investigation. Thus, factor analysis consistently resulted in three factors for the whole datasets. The amount of total variation explained is over 75 percent in factor analysis with varimax rotation. The factor loadings or factor structure matrix with unassociated rotation methods are not always easy to interpret. The nonhierarchical kmean clustering is also used to identify meaningful cluster based on their parameter means of original database.

A survey on student pharmacists' knowledge, attitude and perceptions about drug and poison information elective rotation in Saudi Arabia

Background: Drug and poison information (DPI) elective rotation develops interns into drug information experts, educators, and policymakers. DPI is an important pharmaceutical service built on technical skills, knowledge and expertise. Aim: A pre- and post-rotation survey to assess the current knowledge, attitude and perceptions of student pharmacists about DPI rotation. Methods: Three cohorts of student pharmacists responded to the survey, which was composed of closed- and open-ended questions. Descriptive statistics, McNemar's test, and Chi-square test were utilised for data analysis. Results: Knowledge of primary resources increased from 37.2% to 85.6% at the end of the rotation. In the beginning, only 13.8% were aware of Pharmacy and Therapeutic committee related activities, and 15.9% considered identification adverse drug reactions as auxiliary responsibilities. However, the proportion increased to 82% and 83.5% by the end of the rotation. Both at the beginning and the end, student pharmacists felt the training was essential to appraise literature. Twice the number of respondents expressed that there were job opportunities in the DPI centre post-rotation compared with the pre-rotation response (p<0.001). The perception of responding to queries at their own pace was significantly reversed post-rotation (p<0.001). A significant association was found between opportunities in DPI centre and motivation to choose this rotation (p<0.05). Also, knowledge of primary resources with previous research was significantly associated (p<0.05). Conclusion: Interventions such as journal club, guest lectures and visit to the DPI centre significantly improved the knowledge, attitude and perceptions of student pharmacists towards this DPI rotation.

Quantifying burning efficiency in megacities using the NO₂∕CO ratio from the Tropospheric Monitoring Instrument (TROPOMI)

This study investigates the use of co-located nitrogen dioxide (NO2) and carbon monoxide (CO) retrievals from the TROPOMI satellite to improve the quantification of burning efficiency and emission factors (EFs) over the megacities of Tehran, Mexico City, Cairo, Riyadh, Lahore, and Los Angeles. Efficient combustion is characterized by high NOx (NO+NO2) and low CO emissions, making the NO2∕CO ratio a useful proxy for combustion efficiency (CE). The local enhancement of CO and NO2 above megacities is well captured by TROPOMI at short averaging times compared with previous satellite missions. In this study, the upwind background and plume rotation methods are used to investigate the accuracy of satellite-derived ΔNO2∕ΔCO ratios. The column enhancement ratios derived using these two methods vary by 5 % to 20 % across the selected megacities. TROPOMI-derived column enhancement ratios are compared with emission ratios from the EDGAR v4.3.2 (Emission Database for Global Atmospheric Research v4.3.2) and the MACCity (Monitoring Atmospheric Chemistry and Climate and CityZen) 2018 emission inventories. TROPOMI correlates strongly (r=0.85 and 0.7) with EDGAR and MACCity, showing the highest emission ratio for Riyadh and lowest emission ratio for Lahore. However, inventory-derived emission ratios are 60 % to 85 % higher than TROPOMI column enhancement ratios across the six megacities. The short lifetime of NO2 and the different vertical sensitivity of TROPOMI NO2 and CO explain most of this difference. We present a method to translate TROPOMI-retrieved column enhancement ratios into corresponding emission ratios, thereby accounting for these influences. Except for Los Angeles and Lahore, TROPOMI-derived emission ratios are close (within 10 % to 25 %) to MACCity values. For EDGAR, however, emission ratios are ∼65 % higher for Cairo and 35 % higher for Riyadh. For Los Angeles, EDGAR and MACCity are a factor of 2 and 3 higher than TROPOMI respectively. The air quality monitoring networks in Los Angeles and Mexico City are used to validate the use of TROPOMI. For Mexico City and Los Angeles, these measurements are consistent with TROPOMI-derived emission ratios, demonstrating the potential of TROPOMI with respect to monitoring burning efficiency.

Responses of rhizosphere soil bacteria to 2-year tillage rotation treatments during fallow period in semiarid southeastern Loess Plateau

Background Soil compaction can be mitigated by deep tillage and subsoiling practices following a long period of no-tillage. Fallow tillage rotation methods are frequently used to improve water availability in the soils of the southeastern Loess Plateau region of China. Rhizosphere soil bacteria are ecologically important for the transformation of matter and energy in the plant root system and can be influenced by tillage rotation treatments. However, the effect of tillage rotations on the bacterial community and structure of rhizosphere soil is not well understood. Methods A two-year field experiment was conducted with four tillage rotation treatments, including subsoil–subsoil (SS-SS), subsoil–deep tillage (SS-DT), deep tillage–deep tillage (DT-DT), and the control treatment of no-tillage–no-tillage (NT-NT). Our study was conducted during wheat’s fallow period to investigate the abundance, diversity, and functions of rhizosphere soil bacteria using high-throughput sequencing technology. Results Our results showed that tillage rotation methods significantly influenced the bacterial diversity and composition of the rhizosphere soil in the plough layer (20–40 cm depth) by altering the moisture content of the soil. The metabolism, environmental information processing, and genetic information processing of the bacteria in the rhizosphere soil were affected. The most abundant phyla across all samples were Proteobacteria, Actinobacteria, Acidobacteria, Planctomycetes, Bacteroidetes, Gemmatimonadetes, Frimicutes, Chloroflexi, Nitrospirae, and Verrucomicrobia, which are classic bacterial decomposers in soil. The bacterial diversity and composition was similar for treatments causing higher soil perturbation (SS-DT and DT-DT), which disrupted the balance between aerobic and anaerobic bacteria. The less disruptive tillage methods (SS-SS and NT-NT), preserved the integrity of the soil bacteria. However, the NT-NT treatment may have led to soil compaction, particularly in the 20–40 cm layer. These results suggested that SS-SS was the most effective tillage rotation practice to accumulate soil moisture, maintain the balance between aerobic and anaerobic bacteria, and to enhance the metabolic capacity of rhizosphere soil bacteria. This method may have a significant impact on the sustainable development and farming practices of dryland agriculture.

Methadone rotation for cancer pain: an observational study

ContextMethadone is a useful option in the treatment of cancer pain. Despite its advantages, methadone use is complicated due to high interindividual variability in pharmacokinetics. Various rotation methods from other opioids have been proposed in mostly Caucasian populations.ObjectivesThis study aims to describe our experience with opioid rotation to methadone for management of cancer pain in a predominantly Asian population.MethodsA retrospective review of 52 inpatients initiated on methadone for cancer pain from June 2015 to June 2018 was conducted. Our institution protocol for methadone rotation involves either one of two methods (‘Stop-and-go’ or the Edmonton 3-day rotation) based on the morphine-equivalent daily dose (MEDD), using an equianalgesic ratio of 10:1 for MEDD <1000 mg. To account for incomplete cross-tolerance, we further reduce the calculated dose by 30%.ResultsThe majority of patients had mixed nociceptive-neuropathic pain (83%) and the predominant reason for methadone rotation was ineffective analgesia with other opioids (75%). The median MEDD before rotation was 104 mg. Effective analgesia (defined as a decrease in numerical rating scale (NRS) of ≥1 or attainment of NRS ≤3) was achieved within 3 days after rotation in 89% of patients. Patients with an MEDD ≤100 mg/day required a greater degree of uptitration of methadone dose after rotation compared with those with an MEDD >100 mg/day.ConclusionRotation to methadone according to our protocol is effective in achieving adequate analgesia in most patients experiencing nociceptive-neuropathic pain. Our results also suggest that a fixed equianalgesic ratio of 10:1 may be adequate for patients at low-to-moderate MEDD <400 mg/day.