In recent years, in the pedagogical literature, it has become a common place to talk about the need to modernize, reform not only the entire education system, but also its specific components, that is, restructuring the educational process itself, in particular, the classroom system. The author considers options for methodological approaches and methodological techniques for the implementation of a modern lesson-research in the museum space. For example, a lesson in literature for grade 11 is used on the topic: “Symbolism, Acmeism, Futurism as Styles of Life and Creativity”, which was developed at the State Literary Museum within the framework of the “Lesson in the Museum” project. The analysis of the results obtained is carried out, and practical recommendations are given