COVID-19-Associated Invasive Pulmonary Aspergillosis in the Intensive Care Unit: A Case Series in a Portuguese Hospital

Invasive pulmonary aspergillosis (IPA) has become a recognizable complication in coronavirus disease 2019 (COVID-19) patients admitted to intensive care units (ICUs). Alveolar damage in the context of acute respiratory distress syndrome (ARDS) appears to be the culprit in facilitating fungal invasion in COVID-19 patients, leading to a COVID-19-associated pulmonary aspergillosis (CAPA) phenomenon. From November 2020 to 15 February 2021, 248 COVID-19 patients were admitted to our ICUs, of whom ten patients (4% incidence) were classified as either probable (six) or possible (four) CAPA cases. Seven patients had positive cultural results: Aspergillus fumigatus sensu stricto (five), A. terreus sensu stricto (one), and A. welwitschiae (one). Five patients had positive bronchoalveolar lavage (BAL) and galactomannan (GM), and two patients had both positive cultural and GM criteria. All but two patients received voriconazole. Mortality rate was 30%. Strict interpretation of classic IPA definition would have resulted in eight overlooked CAPA cases. Broader diagnostic criteria are essential in this context, even though differentiation between Aspergillus colonization and invasive disease might be more challenging. Herein, we aim to raise awareness of CAPA in view of its potential detrimental outcome, emphasizing the relevance of a low threshold for screening and early antifungal treatment in ARDS patients.

Digital Contact Tracing Against COVID-19 in Europe: Current Features and Ongoing Developments

The SARS-CoV-2 pandemic is a public health challenge of unprecedented scale. In the midst of the first wave of the pandemic, governments worldwide introduced digital contact tracing systems as part of a strategy to contain the spread of the virus. In Europe, after intense discussion about privacy-related risks involving policymakers, technology experts, information technology companies, and—albeit to a limited extent—the public at large, technical protocols were created to support the development of privacy-compatible proximity tracing apps. However, as the second wave of SARS-CoV-2 sweeps the continent, digital contact tracing in Europe is evolving in terms of both technological and governance features. To enable policymakers to harness the full potential of digital health tools against SARS-CoV-2, this paper examines the evolution of digital contact tracing in eight European countries. Our study highlights that while privacy and data protection are at the core of contact tracing apps in Europe, countries differ in their technical protocols, and in their capacity to utilize collected data beyond proximity tracing alone. In particular, the most recently released apps tend to offer users more granular information about risk in specific locations, and to collect data about user whereabouts, in order to enhance retrospective contact tracing capacity. These developments signal a shift from a strict interpretation of data minimization and purpose limitation toward a more expansive approach to digital contact tracing in Europe, calling for careful scrutiny and appropriate oversight.

Three Ways of Being Non-Material

This paper develops a probabilistic analysis of conditionals which hinges on a quantitative measure of evidential support. In order to spell out the interpretation of ‘if’ suggested, we will compare it with two more familiar interpretations, the suppositional interpretation and the strict interpretation, within a formal framework which rests on fairly uncontroversial assumptions. As it will emerge, each of the three interpretations considered exhibits specific logical features that deserve separate consideration.

Memorization in DSS, NT, Talmud and Patristic Documents

The history of civilization has its own uniqueness. There is an era in which all forms of knowledge must be memorized. However, after the advent of the printing press, many books circulated that could be a source of knowledge. And after this post-modern era arrives, all knowledge is available at hand via smart-phone at any time.According to historical records, education in the Jewish tradition is very strict. From an early age, a human child has been accustomed to remember what has been learned as part of life. There are four records in history to understand the practice of learning in understanding God's Law carefully and memorizing it. These sources from different eras testify simultaneously that memorization is a must for Jewish education context both at home, public school and synagogue. The sectarian, in Qumran, maintained their own strict interpretation of the Law. Family was still the chief institution and primary context for the dispensation of elementary instruction; although the scribes, Pharisees and learned rabbis played a major role in Jewish education during the NT era. Talmud is more specific about the age of studying and the sign of mastering. Origen also was trained since his childhood by his father, Leonides, to memorize Scripture daily and recite them every day.

Trade Mark Law’s Identity Crisis (Part 1)

The concept of ‘substantial identity’ has not been the subject of sustained critical inquiry in Australian trade mark law, notwithstanding that it plays a crucial role in relation to trade mark ownership, non-use, amendments to representations, and the criminal offences. The first part of this two-part article reveals, through novel doctrinal analysis, how over the course of the twentieth century a settled, strict interpretation of substantial identity took shape in Australian trade mark law. This orthodox interpretation was recently disrupted by the Full Court of the Federal Court in Accor Australia & New Zealand Hospitality Pty Ltd v Liv Pty Ltd and Pham Global Pty Ltd v Insight Clinical Imaging Pty Ltd. In these decisions the Court reinterpreted earlier High Court authority to set up a new, significantly more expansive test of substantial identity – one that is already starting to have a major, and concerning, impact throughout Australia’s trade marks system.

Compulsory jurisdiction under the law of the Sea Convention: its achievements and limits

Part XV of the United Nations Convention on the Law of the Sea (UNCLOS) establishes a special regime for the settlement of international disputes concerning its interpretation or application. Thanks to the mechanism of the enhanced compulsory jurisdiction provided by Section 2, various cases have been referred to the court or tribunals. Accumulation of the precedents has contributed to the clarification of the interpretation and application of the provisions relevant to the functions of the compulsory jurisdiction of international court and tribunals. This article examines the achievements and limits of the dispute settlement mechanism of Part XV. As far as the choice of the procedures in accordance with Article 287 is concerned, it is possible to say that the choice made by State Parties is respected as much as possible. Article 286 sets out the following requirements for a State Party to resort to the compulsory jurisdiction under Section 2: existence of a dispute concerning the interpretation or application of the UNCLOS; no settlement has been reached by recourse to Section 1; subject to the limitations and optional exceptions in accordance with Section 3. With regard to the first requirement, the ITLOS and arbitral tribunals have examined the subject-matter of the dispute before them and have tried to identify those concerning the interpretation or application of the UNCLOS. It is possible to say that examining the second requirement, the ITLOS and arbitral tribunals have emphasized the sound function of the compulsory dispute settlement mechanism under Section 2. As the third requirement relates to the scope of the compulsory jurisdiction of the court and tribunals, the ITLOS and arbitral tribunals have strictly interpreted the terms of Articles 297 and 298. Their Strict interpretation have allowed the Applicant to resort to the compulsory dispute settlement under Section 2. It is also necessary to note the strategic use of Article 300 in the arguments concerning the breach of the obligations under the UNCLOS in various precedents.

Wykładnia celowościowa pojęcia „rodzina”. Glosa krytyczna do Wyroku WSA w Szczecinie z dnia 18 stycznia 2018, II SA/Sz 1199/17

The commented judgement refers to the kind of interpretation of the term “family” in the scope of its members. The choice of interpretation is necessary for examine of possibility of granting the one-time financial support for the birth of the child. The key problem of the case is the question whether the father who does not stay actually with mother and child contains the family. According to the strict interpretation father belongs to the family and his income should be taken into account. WSA decided to use the teleological definition of family which takes into account only members actually forming family and excluded father from community of family. In that way his income is not subject of verification. According to the author of the commented judgement interpretation preferred by WSA is contra-legem, releases father from his futures duties and presents dangerous corruption of system of family law. The father cannot be excluded from the family in any dimension.

Speaking the Same Language: How the Kodály Method Promotes Disciplinary Literacy

Educators are consistently asked to show their students’ literacy levels; however, the traditional definition of literacy is typically limited to a strict interpretation of reading and writing using text rather than notation. Disciplinary literacy expands the definition of literacy, allowing music educators to teach disciplinary-specific symbology. This article describes how the Kodály concept helps students process sound into symbol, which provides students with specific literacy strategies to convert sound into developmentally appropriate visual representations.