Evaluation of blurring and noise of a medical image using a digital phantom

Blurring and noise are an essential characteristic of a medical image on the imaging system. This study shows the characteristics of blurring and noise of a medical image using a digital phantom. A square-shaped digital phantom was produced with pixels that consist of black and white. The line profile was selected on a binary digital image. An image with noise added was generated and a corresponding line profile was also drawn. The degree of noise was increased using the gaussian noise value. The blurring images obtained by applying gaussian blur to a digital phantom was produced similarities to real images. Also, the degree of blurring was increased using the gaussian blur value. As noise increased, the standard deviation of pixels inside and background the object also increased. However, the boundary of the object was retained. As image blurring increased, the boundary of the object was not clearly distinguished. However, the standard deviation of pixels inside and background the object was retained. When extreme noise and blurring are increased, the resulting images are different. For adding noise, the shape is visually maintained. However, the blurred image does not maintain a square shape. Therefore, it is shown that blurring due to movement of object cannot maintain original form. In the image processing method, the reduction of noise is achieved through blur processing. The noise was reduced through blur processing in the image with noise. The degree of noise decreased, but the ambiguity of the boundary increased.

Assessment of MicroPET Image Quality Based on Reconstruction Methods and Post-Filtering

The accuracy of positron emission tomography (PET) imaging is hampered by the partial volume effect (PVE), which causes image blurring and sampling. The PVE produces spillover phenomena, making PET analysis difficult. Generally, the PVE values vary based on reconstruction methods and filtering. Thus, selection of the proper reconstruction and filtering method can ensure accurate and high-quality PET images. This study compared the values of factors (recovery coefficient (RC), uniformity, and spillover ratio (SOR)) associated with different reconstruction and post-filtering methods using a mouse image quality phantom (NEMA NU 4), and we present an effective approach for microPET images. The PET images were obtained using a microPET scanner (Inveon, Siemens Medical Solutions, Malvern, PA, USA). PET data were reconstructed and/or post-filtered. For tumors smaller than 3 mm, iterative reconstruction methods provided better image quality. For tumor sizes bigger than 3 mm, reconstruction methods without post-filtering showed better results.

Sparse Representation Based Inverse Halftoning with Boosted Dictionary1

Halftoning image is widely used in printing and scanning equipment, which is of great significance for the preservation and processing of these images. However, because of the different resolution of the display devices, the processing and display of halftone image are confronted with great challenges, such as Moore pattern and image blurring. Therefore, the inverse halftone technique is required to remove the halftoning screen. In this paper, we propose a sparse representation based inverse halftone algorithm via learning the clean dictionary, which is realized by two steps: deconvolution and sparse optimization in the transform domain to remove the noise. The main contributions of this paper include three aspects: first, we analysis the denoising effects for different training sets and the redundancy of dictionary; Then we propose the improved a sparse representation based denoising algorithm through adaptively learning the dictionary, which iteratively remove the noise of the training set and upgrade the quality of the dictionary; Then the error diffusion halftone image inverse halftoning algorithm is proposed. Finally, we verify that the noise level in the error diffusion linear model is fixed, and the noise level is only related to the diffusion operator. Experimental results show that the proposed algorithm has better PSNR and visual performance than state-of-the-art methods.

T2-PROPELLER Compared to T2-FRFSE for Image Quality and Lesion Detection at Prostate MRI

Purpose: The primary objective was to compare T2-FRFSE and T2-PROPELLER sequences for image quality. The secondary objective was to compare the ability to detect prostate lesions at MRI in the presence and absence of motion artefact using the 2 sequences. Methods: 99 patients underwent 3 T MRI examination of the prostate, including T2-FRFSE and T2-PROPELLER sequences. All patients underwent prostate biopsy. Two independent readers rated overall image quality, presence of motion artefact, and blurring for both sequences using a 5-point Likert scale. Scores were compared for the whole group and for subgroups with and without significant motion artefact. Outcome for lesion detection at an MRI threshold of PI-RADS score ≥3 was compared between T2-FRFSE and T2-PROPELLER. Results: The overall image quality was not significantly different between T2-FRFSE and T2-PROPELLER sequences (3.74 vs. 3.93, p = 0.275). T2-PROPELLER recorded a lesser degree of motion artefact (score 4.53 vs. 3.78, p <0.0001), but demonstrated greater image blurring (score 3.29 vs. 3.73, p <0.001). However, in a subgroup of patients with significant motion artefact on T2-FRFSE, the T2-PROPELLER sequence demonstrated significantly higher image quality (3.46 vs. 2.49, p <0.001). T2-FRFSE and T2-PROPELLER showed comparable positive predictive values for lesion detection at 93.2% and 97.7%, respectively. Conclusions: T2-PROPELLER provides higher quality imaging in the presence of motion artefact, but T2-FRFSE is preferred in the absence of motion. T2-PROPELLER is therefore recommended as a secondary T2 sequence when imaging requires repeat acquisition due to motion artefact.

Lost photon enhances superresolution

Quantum imaging can beat classical resolution limits, imposed by the diffraction of light. In particular, it is known that one can reduce the image blurring and increase the achievable resolution by illuminating an object by entangled light and measuring coincidences of photons. If an n-photon entangled state is used and the nth-order correlation function is measured, the point-spread function (PSF) effectively becomes $$\sqrt{n}$$ n times narrower relatively to classical coherent imaging. Quite surprisingly, measuring n-photon correlations is not the best choice if an n-photon entangled state is available. We show that for measuring (n − 1)-photon coincidences (thus, ignoring one of the available photons), PSF can be made even narrower. This observation paves a way for a strong conditional resolution enhancement by registering one of the photons outside the imaging area. We analyze the conditions necessary for the resolution increase and propose a practical scheme, suitable for observation and exploitation of the effect.

Reducing Susceptibility Distortion Related Image Blurring in Diffusion MRI EPI Data

Diffusion magnetic resonance imaging (MRI) is an increasingly popular technique in basic and clinical neuroscience. One promising application is to combine diffusion MRI with myelin maps from complementary MRI techniques such as multi-parameter mapping (MPM) to produce g-ratio maps that represent the relative myelination of axons and predict their conduction velocity. Statistical Parametric Mapping (SPM) can process both diffusion data and MPMs, making SPM the only widely accessible software that contains all the processing steps required to perform group analyses of g-ratio data in a common space. However, limitations have been identified in its method for reducing susceptibility-related distortion in diffusion data. More generally, susceptibility-related image distortion is often corrected by combining reverse phase-encoded images (blip-up and blip-down) using the arithmetic mean (AM), however, this can lead to blurred images. In this study we sought to (1) improve the susceptibility-related distortion correction for diffusion MRI data in SPM; (2) deploy an alternative approach to the AM to reduce image blurring in diffusion MRI data when combining blip-up and blip-down EPI data after susceptibility-related distortion correction; and (3) assess the benefits of these changes for g-ratio mapping. We found that the new processing pipeline, called consecutive Hyperelastic Susceptibility Artefact Correction (HySCO) improved distortion correction when compared to the standard approach in the ACID toolbox for SPM. Moreover, using a weighted average (WA) method to combine the distortion corrected data from each phase-encoding polarity achieved greater overlap of diffusion and more anatomically faithful structural white matter probability maps derived from minimally distorted multi-parameter maps as compared to the AM. Third, we showed that the consecutive HySCO WA performed better than the AM method when combined with multi-parameter maps to perform g-ratio mapping. These improvements mean that researchers can conveniently access a wide range of diffusion-related analysis methods within one framework because they are now available within the open-source ACID toolbox as part of SPM, which can be easily combined with other SPM toolboxes, such as the hMRI toolbox, to facilitate computation of myelin biomarkers that are necessary for g-ratio mapping.

Visuo-vestibular gaze control - conserved subcortical processing

Gaze stabilization compensates for movements of the head or external environment to minimize image blurring, which is critical for visually-guided behaviors. Multisensory information is used to stabilize the visual scene on the retina via the vestibulo-ocular (VOR) and optokinetic (OKR) reflexes. While the organization of neuronal circuits underlying VOR is well described across vertebrates, less is known about the contribution and evolutionary origin of the OKR circuits. Moreover, the integration of these two sensory modalities is still poorly understood. Here, we developed a novel experimental model, the isolated lamprey eye-brain-labyrinth preparation, to analyze the neuronal pathways underlying visuo-vestibular integration which allowed electrophysiological recordings while applying vestibular stimulation using a moving platform, coordinated with visual stimulation via two screens. We show that lampreys exhibit robust visuo-vestibular integration, with optokinetic information processed in the pretectum and integrated with vestibular inputs at several subcortical levels. The enhanced eye movement response to multimodal stimulation favored the vestibular response at increased velocities. The optokinetic signals can be downregulated from tectum. Additionally, saccades are present in the form of nystagmus. The lamprey represents the oldest living group of vertebrates, thus all basic components of the visuo-vestibular control of gaze were present already at the dawn of vertebrate evolution.

Image Representation Using Stacked Colour Histogram

Image representation plays a vital role in the realisation of Content-Based Image Retrieval (CBIR) system. The representation is performed because pixel-by-pixel matching for image retrieval is impracticable as a result of the rigid nature of such an approach. In CBIR therefore, colour, shape and texture and other visual features are used to represent images for effective retrieval task. Among these visual features, the colour and texture are pretty remarkable in defining the content of the image. However, combining these features does not necessarily guarantee better retrieval accuracy due to image transformations such rotation, scaling, and translation that an image would have gone through. More so, concerns about feature vector representation taking ample memory space affect the running time of the retrieval task. To address these problems, we propose a new colour scheme called Stack Colour Histogram (SCH) which inherently extracts colour and neighbourhood information into a descriptor for indexing images. SCH performs recurrent mean filtering of the image to be indexed. The recurrent blurring in this proposed method works by repeatedly filtering (transforming) the image. The output of a transformation serves as the input for the next transformation, and in each case a histogram is generated. The histograms are summed up bin-by-bin and the resulted vector used to index the image. The image blurring process uses pixel’s neighbourhood information, making the proposed SCH exhibit the inherent textural information of the image that has been indexed. The SCH was extensively tested on the Coil100, Outext, Batik and Corel10K datasets. The Coil100, Outext, and Batik datasets are generally used to assess image texture descriptors, while Corel10K is used for heterogeneous descriptors. The experimental results show that our proposed descriptor significantly improves retrieval and classification rate when compared with (CMTH, MTH, TCM, CTM and NRFUCTM) which are the start-of-the-art descriptors for images with textural features.