MENOPAUSAL SYMPTOMS ON THE QUALITY OF LIFE AMONG YEMENI WOMEN IN SANA’A CITY

Background: Menopause is a physiological phenomenon that can strongly affect the quality of life (QOL) of women. Objectives: To analyzes the menopausal associated symptoms among contributors and their effect on quality of life. To also investigate sociodemographic factors affecting QOL. Methods: A cross-sectional study was conducted among 188 perimenopause and menopausal Yemeni women selected randomly from outpatient clinics of the main public hospitals in Sana'a, Yemen. Data was acquired using the Menopause-Specific Quality of Life (MENQOL) questionnaire. Results: The mean age at menopause was found to be 47±3.4. The majority of participants were postmenopausal (71.27 %), and (71.80 %) were married. The most prevalent symptoms were aching muscles and joints (55%), dissatisfaction with personal life (37.7%), night sweat (35%) and avoidance of intimacy (30%). The total scores of menopausal quality of life for each MENQOL domain revealed that the maximum mean score was recorded for physical domain (42.81± 17.87), followed by psychosocial (14.11±5.72), then sexual (6.93±2.46), and finally vasomotor domain (4.78±3.10). Conclusion: The physical and psychosocial domains had upper mean MENQOL scores than vasomotor and sexual domains. There is a need to educate women about menopause and its symptoms and the need to seek medical advice from specialists and find a center for that. Peer Review History: Received: 1 May 2021; Revised: 12 June; Accepted: 28 June, Available online: 15 July 2021 Academic Editor: Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file: Reviewer's Comments: Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewers: Dr. Gulam Mohammed Husain, National Research Institute of Unani Medicine for Skin Disorders, Hyderabad, India, [email protected] Dr. Salfarina Ramli, Department of Pharmacology and Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Puncak Alam, Selangor, Malaysia. [email protected] Dr. Vanina Doris Edo’o, University of Yaounde I, Yaounde, Cameroun, [email protected] Dr. Ahmed Mohammed Al-Haddad, Department of Medical Laboratories, College of Medicine and Health Sciences, Hadhramout University, Al-Mukalla, Yemen, [email protected] [email protected] Similar Articles: PREVALENCE OF RUBELLA IGG ANTIBODIES AMONG PRODUCTIVE-AGE ‎WOMEN IN AL-MAHWEET GOVERNORATE, YEMEN THE ASSOCIATION OF ADULT MALE AND FEMALE INFERTILITY WITH CELIAC DISEASE PATIENTS IN YEMEN

A systematic review of case reports of hepatic actinomycosis

Background Hepatic Actinomycosis (HA) is one of the infections that causes disorders in patients when diagnosed untimely and inappropriately. Methods Case reports on HA in patients published between 2000 and April 2020 were gathered by carrying out a structured search through PubMed/Medline. Results Through a survey of the Medline database, 130 studies were identified and then, 64 cases with HA were included in the final analysis. Asia had the largest share of cases with 37.5% (24 reports), followed by Europe and the Americas. Affected patients were predominantly males (64%) and the overall mortality rate was 1% with only one male patient in his 50 s dying. Nearly all patients (92%) were immunocompetent. However, in four patients, the use of immunosuppressive medication led to depression of the immune system. Most of the patients (80%) experienced complications. In terms of the complications, the most frequent ones were previous history of abdominal surgery (32%) and foreign bodies in the abdominopelvic region (20%). Actinomyces israelii was the most common pathogen isolated from patients. Abdominal pain (66%), fever (62%), weight loss (48%), night sweat, malaise, and anorexia (14%) over about 3.1 months were the most frequently reported clinical symptoms. Extension to one or more surrounding organs was evident in 18 patients (28%). Histopathologic examination confirmed infection in 67% of the patients and samples obtained from liver puncture biopsy (32%) were most frequently used in diagnosis. Surgery or puncture drainage + anti-infection was the most common method to treat patients and penicillin, Amoxicillin, Doxycycline, and ampicillin were the most frequently used drugs to control infection. Conclusion HA should be considered in patients with a subacute or chronic inflammatory process of the liver. With accurate and timely diagnosis of infection, extensive surgery can be prevented.

Factors Influencing Adherence to Tuberculosis Treatment in the Ketu North District of the Volta Region, Ghana

Annually, ten million cases of tuberculosis (TB) and about 1.8 million mortalities are recorded. Adherence to TB treatment not only reduces death outcomes but prevents prolonged sickness, transmission to others, and the development of multidrug-resistant TB. This study is aimed at determining the rate of treatment adherence, knowledge of TB infection, and the possible factors influencing adherence to TB treatment in the Ketu North District in the Volta Region of Ghana. A cross-sectional study design was employed. A semistructured questionnaire was used to obtain data from respondents. Adherence to TB treatment and knowledge level about TB infection were assessed. A Chi-square test analysis was used to determine the variables that were associated with treatment adherence. Logistic regression analysis was used to determine potential factors that contribute to treatment adherence. A total of 125 TB registrants were enrolled in the study. The majority (102 (81.6%)) adhered to the TB treatment regimen. However, the level of knowledge about night sweat being a symptom of TB infection was relatively low (78 (62.4%)). Logistic regression analysis revealed that the male gender was about three times more likely ( OR = 2.978 , 95 % CI = 1.173 ‐ 7.561 ; p = 0.022 ) to be associated with adherence to TB treatment. However, food availability ( OR = 2.208 , 95% CI (0.848-5.753); p = 0.10 ) and household size ( OR = 0.538 , 95% CI (0.195-1.483); p = 0.23 ) were not significantly associated with treatment adherence. In this study, adherence to TB treatment and the knowledge level of TB infection were high. However, the knowledge level of night sweat being a symptom of TB infection was relatively low. Being a male was significantly associated with treatment adherence. An intensified health education on the symptoms of TB infection is therefore recommended.

NEW CLINICAL INSIGHT INTO COVID-19, A PROTOTYPE ANECDOTE CASE PRESENTATION.

Globe is going through a never seen devastating pandemic of COVID-19 since December, 2019. Now, after a span of six months, COVID-19 is no more new and many characteristics of the virus, it’s path physiology, clinical features, disease progression and management came forth. This is truly remarkable and we salute to the global fraternity. We learnt a many. Disease course is defined as of continuous 10 days, if everything else is normal. Third to eighth day is the defined risk period and ninth to twelfth day is the period of deterioration in symptomatic. Symptoms developing after 21 days defined to be recurrence and no such definite incidents is yet detected. To the contrary of all the cases we find in our day to day practice in different COVID centers, here is an anecdote case report of an elderly doctor with two definitive peaks of symptoms within the defined disease course of 10 days, which is unique and not reported elsewhere till date. Sore, wet and tingling nose along with night sweat with or without fever are the earliest and most consistent features of covid-19 as we found in this case report and later confirmed by analyzing in all other cases where most of the cases reported these symptoms.

PREVALENCE OF PULMONARY TUBERCULOSIS AMONG CHILDREN LIVING IN SAMARU, ZARIA, NIGERIA: A CASE STUDY OF ‘AL MAJIRI’ CHILDREN

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, and it is still a major health problem in Nigeria especially among people with poor socio-economic status. This study was conducted with the aim of determining the prevalence of tuberculosis among two study subjects living in Hayin Dogo community of Samaru, Zaria, Kaduna state: “Al majirai” (Qur’anic school children) and children showing respiratory symptoms The major focus of this study is the al majirai, due to their unhygienic, overcrowded living environments and poor nutritional status. Two hundred sputum samples were collected from the al-majirai, and one hundred from the other children; convenience sampling method was employed. The samples were stained using the Ziehl Neelsen technique and observed microscopically for the presence of acid fast bacilli. The prevalence of acid fast bacilli (AFB) among the Al majirai was 0%, and 12% among the children attending the medical center. Symptoms such as night sweat and bloody sputum, as well as risk factors such as malnutrition and poor housing hygiene were found to be significantly associated with the infection in the children showing respiratory symptoms and attending the Ahmadu Bello University medical center (P<0.05). Highest occurrence of the AFB was observed in children within the ages, 15-18 years, as well as among the male children. Even though a high percentage of the Almajirai were exposed to overcrowding (86%) and poor housing hygiene (79%), there were no positive cases among them. Perhaps, other diagnostic methods other than Ziehl Neelsen could provide more comprehensive information.

Gastric Sclerosing Epithelioid Fibrosarcoma Harboring a Rare FUS-CREM Fusion

Sclerosing epithelioid fibrosarcoma (SEF) is a rare, aggressive soft-tissue tumor, commonly occurring in upper and lower extremities, the limb girdle, and the head and neck, which shows morphologic and molecular overlap with low-grade fibromyxoid sarcoma. For SEF in soft tissues, 100 case reports have been published. To our knowledge, the present case is the first to be reported in English literature for a primary SEF of the stomach with a rare FUS-CREM fusion. We report a case of gastric SEF in a 35-year-old female who presented with nonspecific symptoms, including night sweat, cough, and iron deficiency anemia for the past few months. Further workup showed, on computed tomography, a large, heterogeneously enhancing and centrally necrotic left upper quadrant mass, which measured approximately 8.4 cm. A laparoscopic partial gastrectomy with distal pancreatectomy and splenectomy was performed. Histological examination and immunohistochemical staining suggested the diagnosis of primary gastric SEF, which was later confirmed by sarcoma fusion panel showing FUS-CREM fusion. In this article, we report this first case of SEF in the stomach with a rare FUS-CREM fusion, which has been previously reported only once in SEFs of soft tissue.

Comparing the Effect of Face-to-Face with Phone Counselling Based on Cognitive-Behavioral Therapy on Vasomotor Symptoms in Postmenopausal Women: A Randomized Controlled Trial

Background: Hot flash and night sweat (HF/NS) are the most common complication in menopause that affects the quality of life of women. The present study was conducted with the aim of comparing the effectiveness of the phone with face-to-face counseling based on cognitive-behavioral therapy for vasomotor symptoms of postmenopausal women.Methods: The present study was a randomized clinical trial. In this study, 40 eligible postmenopausal women were randomly assigned to one of face-to-face or phone counseling methods using the block randomization. Six counseling sessions were weekly held for each person and women requested to record their hot flashes and night sweat in a diary. Data were analyzed using chi-square, ANCOVA, and independent t-test.Results: Thirty- six women completed the study. Women in two groups showed a significant improvement in the frequency, severity, and duration of hot flashes and the frequency and severity of night sweats after the intervention (P <0.001). Weekly means of hot flashes and night sweats, decreased after the intervention in both groups (face-to-face group: HF frequency from 31.92±7.98 to 18.83±7.35, HF severity from 2.24±0.28 to 1.21±0.23, HF duration from 4.22±1.17 min to 2.79±0.91min, NS frequency from 2.34±0.31 to 1.21±0.24 and NS severity from 1.70±0.34 to 1.03±0.29 and also in phone counseling group: HF frequency from 33.32±7.77 to 19.53±7.7, HF severity from 2.23±0.24 to 1.20±0.18, HF duration from 4.29±1.23 min to 2.68±0.95min, NS frequency from 2.33±0.31 to 1.14±0.16 and NS severity from 1.59±0.34 to 1.01±0.30). There was no significant difference between groups after the intervention in terms of HF frequency, severity, and duration, as well as NS frequency, and severity (p>0.05). Conclusion: Based on the results of this study, using of face-to-face and phone counseling methods based on cognitive-behavioral therapy had a similar effect on the reducing of frequency, severity and duration of hot flashes as well as the frequency and severity of night sweats. Using phone counseling in women who have difficulty to attend the clinic is recommended.Trial registration number: IRCT20180918041065N1 Website: https://www.irct.ir/login

A Rare Complication of Thymoma: Pure White Cell Aplasia in Good’s Syndrome

Pure white cell aplasia (PWCA) is a rare manifestation of thymoma. It is characterized by agranulocytosis with absent myeloid precursors in the bone marrow and normal hematopoiesis for other cell lines. Here we describe a 65-year-old female patient who presented with three days of fever and night sweat. Chest CT revealed an anterior mediastinal mass. A biopsy of the mass confirmed a diagnosis of thymoma mixed type A and B2. The patient developed a severe neutropenia, and her bone marrow revealed significantly decreased neutrophil-lineage cells, rare to absent B cells, and defective T cells, consistent with PWCA. Following thymectomy, a complete resolution of PWCA was achieved via multimodality therapy of intravenous immunoglobulins, granulocyte colony-stimulating factor, and immunosuppressant. This report highlights the care complexity regarding treatment choices and decision to perform thymectomy in patients presenting with PWCA.