Testosterone Increases the Emission of Ultrasonic Vocalizations With Different Acoustic Characteristics in Mice

Testosterone masculinizes male sexual behavior through an organizational and activational effects. We previously reported that the emission of ultrasonic vocalizations (USVs) in male mice was dependent on the organizational effects of testosterone; females treated with testosterone in the perinatal and peripubertal periods, but not in adults, had increased USV emissions compared to males. Recently, it was revealed that male USVs have various acoustic characteristics and these variations were related to behavioral interactions with other mice. In this regard, the detailed acoustic characteristic changes induced by testosterone have not been fully elucidated. Here, we revealed that testosterone administered to female and male mice modulated the acoustic characteristics of USVs. There was no clear difference in acoustic characteristics between males and females. Call frequencies were higher in testosterone propionate (TP)-treated males and females compared to control males and females. When the calls were classified into nine types, there was also no distinctive difference between males and females, but TP increased the number of calls with a high frequency, and decreased the number of calls with a low frequency and short duration. The transition analysis by call type revealed that even though there was no statistically significant difference, TP-treated males and females had a similar pattern of transition to control males and females, respectively. Collectively, these results suggest that testosterone treatment can enhance the emission of USVs both in male and female, but the acoustic characteristics of TP-treated females were not the same as those of intact males.

Beer Polyphenols—Bitterness, Astringency, and Off-Flavors

The acceptance of beer among consumers is most influenced by the taste and aroma. Polyphenols are widely responsible for both. Whereas polyphenols do not always result in a positive flavor and taste, they can surely impart certain off-flavors, which will be mentioned in this paper. However, the aftertaste is an important component of the beer-tasting experience and acceptance. The aftertaste, including astringency, may largely influence consumers’ consumption preference and behavior. Bitterness is one of the main, desirable characteristics of beer, but to an untrained consumer, it can often be mistaken with astringency. This review aims to describe the differences between these two properties. Both attributes derive from the same beer components, polyphenols from barley and hop, but there is a distinctive difference between them. To understand the complexity of bitterness and astringency, polyphenols behavior, characteristics, and stability during the brewing process are also described in this review.

The Glycemic Index of Food- Should It Be Gender Specific?

Glycemic index (GI) was developed to categorize dietary carbohydrates based on their overall effect on postprandial blood glucose. Low GI foods demand a lower insulin response compared to high GI foods. This is expected to decrease the incidence of insulin resistance, the development of obesity, and hypertension, which are risk factors for diabetes and cardiovascular disease. Hence, it was recommended to add GI as a valid methodology complementing other dietary aspects that need to be applicable to both genders. In this study, we aimed to investigate the effect of gender difference on GI in healthy, normal BMI males and females. Healthy, non-smoking adults age between 18 -35 years of normal BMI, were recruited. Subjects were included following initial screening using a structured questionnaire and blood tests to exclude diabetes, dyslipidemia, and/or hypertension cases. A standard 50 g glucose tolerance test was performed for two visits for each sugar (glucose and sucrose). Blood was collected at fasting, then at 15,30,45,60,90,120 min after the sugar consumption and the area under the curve was calculated. A total of 11 men and ten women were included in the study after excluding prediabetics and participants with abnormal liver enzymes. The mean GI for the whole sample was 69. A distinctive difference between males and females was noticed in the GI and the response curve. For males, the GI for sucrose was 77, and the response curve peaked at 30 min, followed by a sharp decline below baseline at 2h. On the other hand, the GI for females was 60, and the curve peaked at 45 min. In conclusion, our study showed that there is a clear difference in GI between men and women. A larger study is needed to clarify this further and prove or disprove the need for separate GI lists for men and women.

Testosterone Increases the Emission of Ultrasonic Vocalizations With Different Acoustic Characteristics in Mice

: Testosterone masculinizes male sexual behavior through an organizational effect during the perinatal period. We previously reported that the emission of ultrasonic vocalizations (USVs) in male mice was dependent on the organizational effects of testosterone; females treated with testosterone in the perinatal period had increased USV emissions compared to males. Recently, it was revealed that male USVs have various acoustic characteristics and these variations were related to behavioral interactions with other mice. In this regard, the detailed acoustic character changes induced by testosterone have not been fully elucidated. Here, we revealed that testosterone administered to female mice during the perinatal period modulated the acoustic characteristics of USVs. There was no clear difference in acoustic characters between males and females. Call frequencies were higher in TP-treated males and females compared to control males and females. When the calls were classified into nine types, there was also no distinctive difference between males and females, but TP increased the number of calls with a high frequency, and decreased the number of calls with a low frequency and short duration. The transition analysis by call type revealed that even though there was no statistically significant difference, TP-treated males and females had a similar pattern of transition to control males and females, respectively. Collectively, these results suggest that testosterone treatment can enhance the emission of USVs in females, but the acoustic characteristics are not the same as those of intact males.

Quantitative measurement of bubble textures in pumice clasts using a digital stereo microscope with low-angled ring illumination

Quantitative analysis of bubble textures in a large number of volcanic pyroclasts is critical to investigating the eruption dynamics in a volcanic conduit. Here, we used a digital stereo microscope with low-angled ring illumination (DSM-LaRI) to measure bubble textures on unpolished cutting surfaces of pumice clasts. As the DSM-LaRI enhances brightness contrast between the bubbles (pores) and the matrix, we easily obtained the two-dimensional data on the size and shape of bubbles by image analysis. The DSM-LaRI imaging provided the distributions of size and shape of bubbles at least 50 µm across. We applied the DSM-LaRI to analyze more than 1000 pumice clasts from the 232 AD Taupo eruption and measured the mean bubble radius ($$\overline{R}$$ R ¯ ) and the mean deformation degree ($$\overline{D}$$ D ¯ ) in the individual clasts. The distribution of $$\overline{R}$$ R ¯ and $$\overline{D}$$ D ¯ in each layer showed a distinctive difference between the fallout and the flow deposits. These quantitative data are consistent with a qualitative classification in a previous study. Although the new DSM-LaRI method has the disadvantage of the low spatial resolution, it allows for the analysis of a large number of pumice clasts in a short time, which can address larger scale heterogeneity, by efficiently generating a large representative suite of bubble size and shape data to link bubble textures to conduit processes. This provides vital information for quantitatively modeling eruption dynamics.

The double peaked El Niño and its physical processes

Recently, El Niño diversity has been paid much attention due to its different global impacts. However, most studies have focused on a single warm peak in sea surface temperature anomalies (SSTAs), either in the central Pacific or the eastern Pacific. Here, we demonstrate from observational analyses that several recent El Niño events show double warm peaks in SSTA – called “Double Peaked (DP) El Niño” – that have only been observed since 2000. The DP El Niño has two warm centers, which grow concurrently but separately, in both the central and eastern Pacific. In general, the atmospheric and oceanic patterns of the DP El Niño are similar to those of the Warm Pool (WP) El Niño from the development phase, such that the central Pacific peak is developed by the zonal advective feedback and reduced wind speed anomalies. However, a distinctive difference exists in the eastern Pacific where the DP El Niño has a second SSTA peak. In addition, the DP El Niño shows more distinctive anomalous precipitation along the Pacific intertropical convergence zone (ITCZ) compared with the WP El Niño. We demonstrate that the peculiar precipitation anomalies along the Pacific ITCZ play a critical role in enhancing the equatorial westerly wind stress anomalies, which help to develop the eastern SSTA peak by deepening the thermocline in the eastern Pacific.

Normative disagreement: a functional account for inferentialists

There was a time when meta-ethical expressivism seemed to be the only game in town for meta-ethical non-representationalists. In recent years, though, meta-ethical inferentialism has emerged as a promising non-representationalist alternative. So far, however, inferentialists lack something that would really allow them to draw level with expressivists. This is an explanation for the distinctive difference between normative and descriptive vocabulary when it comes to disagreement—something expressivists can explain in terms of the difference between representational and desire-like states and which constitutes one of the primary motivations for expressivism. This paper develops a novel and distinctive account for this difference on behalf of inferentialists, based on the different functions of these two vocabularies. Not only does this account help inferentialists, it also shows how non-representionalist accounts can capture the relevant disagreement phenomena without appealing to the sorts of desire-like states expressivists tend to appeal to.

Agro-biološka raznolikost slovenskih ekotipov in standardnih sort navadne pasje trave (Dactylis glomerata L.): primerjava in agronomska vrednost

<p>Characterisation and evaluation of accessions, e.g. ecotypes of cultivated plants, are the primary task of each agricultural gene bank. In a field experiment, agro-biological diversity and agronomic value of 15 Slovene ecotypes (group 1) and 7 standard varieties (group 2) of cocksfoot (<em>Dactylis glomerata</em> L.) were investigated during the 2015-2019 period. A particular emphasis was given to the comparison of the two groups. The spaced plant experiment with 20 single plants of each treatment entity per replicate was arranged in a randomized complete block design with three replicates. Significant differences among investigated entities were confirmed for all agro-biological traits (<em>p</em> &lt; 0.001). The same holds when the groups were compared (<em>p</em> &lt; 0.001) except for the infection with leaf fungal diseases (<em>p</em> = 0.113).Considering these differences varieties possessed higher agronomic value than ecotypes. In general, the intra-population diversity of Slovene ecotypes was higher than that of standard varieties and represented a higher portion of the ecotype complete variance. Principal component analysis (PCA) of all investigated traits showed a distinctive difference between ecotypes and varieties and higher similarity within the variety group than within the ecotype group. PCA also showed that the ecotypes can be separated into two subgroups, which however cannot be explained by the characteristics of ecotype origin.</p>

Tradisional Dan Modernitas Tipologi Arsitektur Masjid Hunto Sultan Amay Gorontalo

A mosque is a symbol of the magnificence of Islam, which has an important significance in Islamic culture and civilization, and is a symbol of harmony in human life with Nature and the environment.The appearance of the Hunto Mosque building is a combination of elements of local architecture and Islamic architecture which is full of meaning. Some of these parts are the four pillars of the mosque which are interpreted as the four companions of the prophet, six wooden doors, a pulpit whose ornaments come from Gujarat, India, a drum, and an old well where ablution is of course as old as the Hunto Mosque. Hunto Mosque, the first mosque in Gorontalo City, was built in 1495 AD or 899 H, and has an area of 12x12 meters. This study aims to determine in general the form of typology in the form of architectural ornaments at the Sultan Amay mosque.The manifestation of a mosque architectural typology that occurs directly or indirectly, is due to the distinctive difference between a traditional Islamic community-based architectural typology with a modernist Islamic community-based architectural typology, each of which is influenced by the characteristics of the Islamic orientation of society.