The present problem is concerned with two-phase fluid flow through a horizontal porous channel in the presence of uniform inclined magnetic field. The micropolar fluid or Eringen fluid and Newtonian viscous fluid are flowing in the upper and lower regions of the horizontal porous channel, respectively. In this paper, the permeability of each region of the horizontal porous channel has been taken to be different. The effects of various physical parameters like angles of inclination of magnetic field, viscosity ratio, micropolarity parameter, etc., on the velocities, micro-rotational velocity of two immiscible fluids in horizontal porous channel, wall-shear stress, and flow rate have been discussed. The result obtained for immiscible micropolar–Newtonian fluids are compared with the results of two immiscible Newtonian fluids. The obtained result may be used in production of oil from oil reservoirs, purification of contaminated ground water, etc.