elimination goal
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2022 ◽  
Vol 9 ◽  
Author(s):  
Henrique Lopes ◽  
Ricardo Baptista-Leite ◽  
Diogo Franco ◽  
Miguel A. Serra ◽  
Amparo Escudero ◽  
...  

Background: The WHO has defined international targets toward the elimination of hepatitis C by 2030. Most countries cannot be on track to achieve this goal unless many challenges are surpassed. The Let's End HepC (LEHC) tool aims to contribute to the control of hepatitis C. The innovation of this tool combines the modelling of public health policies (PHP) focused on hepatitis C with epidemiological modelling of the disease, obtaining a unique result that allows to forecast the impact of policy outcomes. The model was applied to several countries, including Spain.Methods: To address the stated objective, we applied the “Adaptive Conjoint Analysis” for PHP decision-making and Markov Chains in the LEHC modelling tool. The tool also aims to be used as an element of health literacy for patient advocacy through gamification mechanisms and country comparability. The LEHC project has been conducted in several countries, including Spain. The population segments comprised in the project are: People Who Inject Drugs (PWID), prisoners, blood products, remnant population.Results: A total of 24 PHP related to hepatitis C were included in the LEHC project. It was identified that Spain had fully implemented 14 of those policies to control hepatitis C. According to LEHC's model forecast, the WHO's Hepatitis C elimination goal on reducing the number of patients living with Hepatitis C to 10% can be achieved in Spain by 2026 if current policies are maintained. The model estimates that the total population in Spain, by 2026, is expected to comprise 26,367 individuals living with hepatitis C. Moreover, if the 24 PHP considered for this study are fully implemented in Spain, the elimination goal may be achieved in 2024, with 29,615 individuals living with hepatitis C by that year.Conclusion: The findings corroborate the view that Spain has set great efforts in directing PHP toward Hepatitis C Virus (HCV) elimination by 2030. However, there is still room for improvement, namely in further implementing 10 of the 24 PHP considered for the LEHC project. By maintaining the 14 PHP in force, the LEHC model estimates the HCV elimination in the country by 2026, and by 2024 if further measures are employed to control the disease.


Vaccine ◽  
2021 ◽  
Vol 39 (40) ◽  
pp. 5928-5933
Author(s):  
Serena Marchi ◽  
Edmond J. Remarque ◽  
Simonetta Viviani ◽  
Caterina Rizzo ◽  
Geraldo Tadinho Monteverde Spencer ◽  
...  

2021 ◽  
Vol 15 (7) ◽  
pp. e0009608
Author(s):  
Devika Shanmugasundaram ◽  
Shally Awasthi ◽  
Bhagirathi Dwibedi ◽  
S. Geetha ◽  
Manish Jain ◽  
...  

Background India has set a goal to eliminate measles and rubella/Congenital Rubella Syndrome (CRS) by 2023. Towards this goal, India conducted nationwide supplementary immunization activity (SIA) with measles-rubella containing vaccine (MRCV) targeting children aged between 9 months to <15 years and established a hospital-based sentinel surveillance for CRS. Reliable data about incidence of CRS is necessary to monitor progress towards the elimination goal. Methods We conducted serosurveys in 2019–20 among pregnant women attending antenatal clinics of 6 hospitals, which were also sentinel sites for CRS surveillance, to estimate the prevalence of IgG antibodies against rubella. We systematically sampled 1800 women attending antenatal clinics and tested their sera for IgG antibodies against rubella. We used rubella seroprevalence data from the current survey and the survey conducted in 2017 among antenatal women from another 6 CRS surveillance sites to construct a catalytic models to estimate the incidence and burden of CRS. Result The seroprevalence of rubella antibodies was 82.3% (95% CI: 80.4–84.0). Rubella seropositivity did not differ by age group and educational status. Based on the constant and age-dependent force of infection models, we estimated that the annual incidence of CRS in India was 225.58 per 100,000 live births (95% CI: 217.49–232.41) and 65.47 per 100,000 live births (95% CI: 41.60–104.16) respectively. This translated to an estimated 14,520 (95% CI: 9,225–23,100) and 50,028 (95% CI: 48,234–51,543) infants with CRS every year based on age-dependent and constant force of infection models respectively. Conclusions Our findings indicated that about one fifth of women in the reproductive age group in India were susceptible for rubella. The estimates of CRS incidence will serve as a baseline to monitor the impact of MRCV SIAs, as well progress towards the elimination goal of rubella/CRS.


2021 ◽  
Vol 6 (5) ◽  
pp. e005391
Author(s):  
Raju Ranjha ◽  
Amit Sharma

Despite the decrease in malaria mortality and morbidity, it remains a significant public health problem in India. India is targeting malaria elimination from the country by 2030. Different areas in India are in different phases of malaria elimination. The emerging resistance in vectors as well parasite have added necessity to accelerate the malaria elimination programme. Forested areas remain the foci for malaria transmission due to favourable human and environmental factors. Here, we analysed the longitudinal data from 2000 to 2019 to see the trends in forest malaria in India. Population living in forested areas are major malaria contributors. From 2000 to 2019, ~32% of malaria cases and 42% of malaria related deaths were reported from forested districts which represent only ~6.6% of the total Indian population. Increasing insecticide resistance, a high percentage of submicroscopic infections and challenging to test and treat communities are the crucial components of the prevailing obstacles of forested malaria. To achieve the elimination goal, efforts should be intensified with more resources diverted to the forested areas. Malaria control in forested areas will bring fruitful results for malaria control in India.


2021 ◽  
Vol 30 (9) ◽  
pp. 26-33
Author(s):  
Vu Thi Thu ◽  
Vu Hai Ha ◽  
Pham Dinh Long ◽  
Nguyen Thi Thu Ha ◽  
Vu Hoai Nam ◽  
...  

A cross - sectional study was conducted in 63 provinces/cities in Vietnam with the aim to describe the measles/rubella surveillance results in the 2010 - 2019 period. All data reported in the Expanded Program on Immunization (EPI) Report in the period 2010 - 2019. Overall measles/rubella surveillance results showed that almost all regions of the country had achieved the detection target of suspected measles/rubella cases of ≥ 2/100,000 population, while the proportion of suspected measles/rubella cases surveyed and sampled nationwide was 57.7 % and 39.6%, respectively, which did not meet the standards set by World Health Organization (WHO). The proportion of measles/rubella cases surveyed differed signifcantly between regions (χ2 3df = 3500, p < 0.001), with the highest in the Central (80.3%) and the lowest in the Highlands (45.0%). Sampling rates on the number of suspected cases varied between regions (χ2 3df = 1600, p < 0.001). To achieve the measles/rubella elimination goal, standard surveillance system plays an important role in providing valuable information for disease prevention and control.


2021 ◽  
Author(s):  
José Orlinder Nicolas ◽  
Denis Escobar ◽  
Engels Banegas ◽  
José Ramón Valdez ◽  
Rosa Elena Mejía Torres ◽  
...  

Abstract Background As Malaria cases are continuously reported across the globe, epidemiological and integral approaches should be considered for an optimal stratification on endemic areas for elimination goal. In Central America, a 75% reduction in malaria incidence has been reported between 2000 and 2015, similarly, in Honduras, more than 75% of total cases in 2016 were concentrated in 7 municipalities, mainly in Gracias Dios department. Achieve malaria elimination in Honduras demands the implementation of strategies to identify main hotspots. Methods Based on WHO guidelines, local malaria epidemiological data from case-based surveillance system of the Ministry of Health between January and December 2016 were analysed. Furthermore, on field evaluations were carried out in Puerto Lempira municipality, Gracias a Dios department to an analysis validation. Finally, a set of epidemiological components were generated and proposed together with risk-factor description and proposed actions for health system improvement. Results On 2016, Gracias a Dios reported 61% of total malaria cases in Honduras; based on our analysis, 12 micro-areas were identified, including epidemiological, entomological, and socio-demographic information from local technicians. Conclusions Malaria elimination in endemic areas urges implementation of different strategies, here we show the on-field micro-stratification process of 12 “micro-areas” carried out in one endemic department of Honduras. This information provides a more targeted strategy for diagnosis, treatment, and vector control interventions for malaria elimination goal in Honduras.


2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Kinley Penjor ◽  
Tobgyal ◽  
Tandin Zangpo ◽  
Archie C. A. Clements ◽  
Darren J. Gray ◽  
...  

AbstractThe COVID-19 pandemic has resulted in massive global disruptions with considerable impact on the delivery of health services and national health programmes. Since the detection of the first COVID-19 case on 5th March 2020, the Royal Government of Bhutan implemented a number of containment measures including border closure and national lockdowns. Against the backdrop of this global COVID-19 pandemic response, there was a sudden surge of locally-transmitted malaria cases between June to August 2020. There were 20 indigenous cases (zero Plasmodium falciparum and 20 Plasmodium vivax) from a total of 49 cases (seven P. falciparum and 42 P. vivax) in 2020 compared to just two from a total of 42 in 2019. Over 80% of the cases were clustered in malaria endemic district of Sarpang. This spike of malaria cases was attributed to the delay in the delivery of routine malaria preventive interventions due to the COVID-19 pandemic. As a result, Bhutan is unlikely to achieve the national goal of malaria elimination by 2020.


2020 ◽  
Vol 13 (Supplement_1) ◽  
pp. S65-S70
Author(s):  
Patrick J Lammie ◽  
Katherine M Gass ◽  
Jonathan King ◽  
Michael S Deming ◽  
David G Addiss ◽  
...  

Abstract The Global Programme to Eliminate Lymphatic Filariasis (GPELF) was established with the ambitious goal of eliminating LF as a public health problem. The remarkable success of the GPELF over the past 2 decades in carrying out its principal strategy of scaling up and scaling down mass drug administration has relied first on the development of a rigorous monitoring and evaluation (M&E) framework and then the willingness of the World Health Organization and its community of partners to modify this framework in response to the practical experiences of national programmes. This flexibility was facilitated by the strong partnership that developed among researchers, LF programme managers and donors willing to support the necessary research agenda. This brief review summarizes the historical evolution of the GPELF M&E strategies and highlights current research needed to achieve the elimination goal.


2020 ◽  
Vol 13 (Supplement_1) ◽  
pp. S17-S21
Author(s):  
D Ramaiah Kapa ◽  
Ahmed Jamsheed Mohamed

Abstract Background The South-East Asia regional programme to eliminate lymphatic filariasis (LF) was launched in 2000. This study presents the progress and impact of the programme in the region. Methods Mass drug administration (MDA) and morbidity management data were accessed from the WHO preventive chemotherapy databank. The status of the programme in the nine South-East Asia countries was reviewed and progress was assessed. The impact of the programme on LF disease burden was estimated on the basis of the effectiveness of the MDA drugs against microfilaraemia and chronic disease. Results Under the MDA programme, 8.1 billion treatments were delivered in nine countries and 5.7 billion treatments were consumed by the target population during 2001–2018. Three of nine countries eliminated LF. Bangladesh is poised to reach its elimination goal by 2021. In the other five countries, 38–76% of intervention units completed intervention and surveillance is in progress. The MDA programme prevented or cured 74.9 million infections, equivalent to an 84.2% reduction. Close to 1 million lymphoedema patients and 0.5 million hydrocele patients were reported and are being provided with the minimum package of care. Conclusions The South-East Asia region's LF elimination programme reduced the burden of LF appreciably and is moving towards achieving the elimination goal in the next 8–10 y.


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