STUDY OF CRITICAL POWER INTERRUPTION FOR SELFSTARTING SUCCESS

The work is devoted to modeling electromechanical transients when powered from a local source. The object of the study is TKG-1 «Pervomayskaya CHPP», LLC «Shchekinoazot». The time critical for maintaining the initial mode of power interruption is obtained when the design conditions are varied. The problem of evaluating the success of self-launching is programmatically solved in Matlab.

The effects of a special sequential mixed-mode design, and reminders, on panellists’ participation in a probability-based panel study

The sequential mixed-mode strategy has become standard practice in the survey management of longitudinal studies, in order to achieve consistently high response rates. To realise this aim in a cost-efficient way, a first mode is often an online questionnaire, towards which the target persons are pushed, and a second mode is then a telephone interview, offered to those who do not respond to the initial mode. However, the rationale for using the sequential mixed-mode plus “push-to-web” strategy to reduce the burden of choosing between survey modes, in order to maximise survey participation, could be undermined if there is an overlapping field period during which the target persons could choose between two or more offered modes. The use of reminders might be useful in solving this problem of competing risks. In the context of a multiple-panel study, this question was investigated by utilising longitudinal paradata from the fieldwork, as well as procedures of event history analysis that are adequate for the analysis of processes with competing risks. First, for a web survey as the initial mode and computer-assisted telephone interview (CATI) as the subsequent mode, it was found that the idea of a sequential mixed-mode plus “push-to-web” strategy does work even in the case of competing risks in the choice of a survey mode. Second, it was confirmed that reminders are a useful instrument for stimulating panellists to choose the running survey mode. Third, and finally, it was found that this feature of survey management is effective in countering panellists’ procrastination in regard to responding to a survey.

Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC

In bacteria, adenosine 5′-triphosphate (ATP)–binding cassette (ABC) importers are essential for the uptake of nutrients including the nonreducing disaccharide trehalose, a metabolite that is crucial for the survival and virulence of several human pathogens including Mycobacterium tuberculosis. SugABC is an ABC transporter that translocates trehalose from the periplasmic lipoprotein LpqY into the cytoplasm of mycobacteria. Here, we report four high-resolution cryo–electron microscopy structures of the mycobacterial LpqY-SugABC complex to reveal how it binds and passes trehalose through the membrane to the cytoplasm. A unique feature observed in this system is the initial mode of capture of the trehalose at the LpqY interface. Uptake is achieved by a pivotal rotation of LpqY relative to SugABC, moving from an open and accessible conformation to a clamped conformation upon trehalose binding. These findings enrich our understanding as to how ABC transporters facilitate substrate transport across the membrane in Gram-positive bacteria.

Factors Associated with Initial Mode of Breast Cancer Detection among Black Women in the Women’s Circle of Health Study

Mammogram-detected breast cancers have a better prognosis than those identified through clinical breast exam (CBE) or through self-detection, primarily because tumors detected by mammography are more likely to be smaller and do not involve regional nodes. In a sample of 1,322 Black women, aged 40-75 years, diagnosed with breast cancer between 2002 and 2016, we evaluated factors associated with CBE and self-detection versus screening mammogram as the initial mode of breast cancer detection, using multivariable logistic regression models. Compared with screening mammogram, history of routine screening mammogram (OR 0.20, 95% CI: 0.07, 0.54) and performance of breast self-examination (BSE) (OR 0.31, 95% CI: 0.13, 0.74) before diagnosis were associated with lower odds of CBE as the initial mode of detection, while performance of CBEs before diagnosis (OR 11.04, 95% CI: 2.24, 54.55) was positively associated. Lower body mass index (<25.0 kg/m2 vs. ≥35.0 kg/m2: OR 2.46, 95% CI: 1.52, 3.98), performance of BSEs before diagnosis (less than once per month: OR 4.08, 95% CI: 2.45, 6.78; at least monthly: OR 4.99, 95% CI: 3.13, 7.97), and larger tumor size (1.0-2.0 cm vs. <1.0 cm: OR 2.92, 95% CI: 1.84, 4.64; >2.0 cm vs. <1.0 cm: OR 6.41, 95% CI: 3.30, 12.46) were associated with increased odds of self-detection relative to screening mammogram. The odds of CBE and self-detection as initial modes of breast cancer detection among Black women are independently associated with breast care and breast cancer screening services before diagnosis and with larger tumors at diagnosis.

Электрохимическая аморфизация как метод повышения скоростных характеристик кристаллических кремниевых анодов для литий-ионных аккумуляторов

Anodes made of macroporous silicon were studied. The galvanostatic cyclic tests carried out in half-cells with a Li counter electrode in the mode, when charging capacity was limited by Q1 = 1000 mAh/g, showed that the inclusion into the test program of a modifying cycle with an increased time of electrochemical lithiation allows to increase the charge/discharge rate upon the returning back to the initial mode. To interpret the obtained results, a two-phase model with a sharp a-LixSi/c-Si boundary was used. The introduction of a larger amount of lithium during the modifying cycle leads to an increase in the thickness of the amorphous layer, within which the introduction and extraction of lithium in subsequent cycles occur at a higher rate.

The Effect of a Dominant Initial Single Mode on the Kelvin–Helmholtz Instability Evolution: New Insights on Previous Experimental Results

This paper brings new insights on an experiment, measuring the Kelvin–Helmholtz (KH) instability evolution, performed on the OMEGA-60 laser facility. Experimental radiographs show that the initial seed perturbations in the experiment are of multimode spectrum with a dominant single-mode of 16 μm wavelength. In single-mode-dominated KH instability flows, the mixing zone (MZ) width saturates to a constant value comparable to the wavelength. However, the experimental MZ width at late times has exceeded 100 μm, an order of magnitude larger. In this work, we use numerical simulations and a statistical model in order to investigate the vortex dynamics of the KH instability for the experimental initial spectrum. We conclude that the KH instability evolution in the experiment is dominated by multimode, vortex-merger dynamics, overcoming the dominant initial mode.

A Microstructural Study of Load Distribution in Cartilage: A Comparison of Stress Relaxation versus Creep Loading

The compressive response of articular cartilage has been extensively investigated and most studies have focussed largely on the directly loaded matrix. However, especially in relation to the tissue microstructure, less is known about load distribution mechanisms operating outside the directly loaded region. We have addressed this issue by using channel indentation and DIC microscopy techniques that provide visualisation of the matrix microstructural response across the regions of both direct and nondirect loading. We hypothesise that, by comparing the microstructural response following stress relaxation and creep compression, new insights can be revealed concerning the complex mechanisms of load bearing. Our results indicate that, with stress relaxation, the initial mode of stress decay appears to primarily involve relaxation of the surface layer. In the creep loading protocol, the main mode of stress release is a lateral distribution of load via the mid matrix. While these two modes of stress redistribution have a complex relationship with the zonally differentiated tissue microstructure and the depth of strain, fourmechanostructuralmechanisms are proposed to describe succinctly the load responses observed.