Multifunctional Single‐Component Polypeptide Hydrogels: The Gelation Mechanism, Superior Biocompatibility, High Performance Hemostasis, and Scarless Wound Healing

2021 ◽  
pp. 2101809
Author(s):  
Qian Bai ◽  
Lin Teng ◽  
Xueliang Zhang ◽  
Chang‐Ming Dong
Keyword(s):  
Wound Healing ◽  
High Performance ◽  
Single Component ◽  
Gelation Mechanism

Recent advances in white light-emitting diodes of carbon quantum dots

Nanoscale ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 4826-4832 ◽  
Author(s):  
Ping He ◽  
Yuxin Shi ◽  
Ting Meng ◽  
Ting Yuan ◽  
Yunchao Li ◽  
...  
Keyword(s):  
Quantum Dots ◽  
White Light ◽  
High Performance ◽  
Light Emitting Diodes ◽  
Carbon Quantum Dots ◽  
Single Component ◽  
Light Emitting ◽  
Recent Advances ◽  
White Light Emitting Diodes

In this mini review, we update the latest research in the design of high-performance WLEDs with different correlated color temperatures by tuning the red component using red emissive CQDs and single-component white emissive CQDs.

scholarly journals Proteomic analysis of bladder biopsies from interstitial cystitis/bladder pain syndrome patients with and without Hunner’s lesions reveals differences in expression of inflammatory and structural proteins

BMC Urology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Elijah P. Ward ◽  
Sarah N. Bartolone ◽  
Michael B. Chancellor ◽  
Kenneth M. Peters ◽  
Laura E. Lamb
Keyword(s):  
Wound Healing ◽  
Interstitial Cystitis ◽  
High Performance ◽  
Stress Proteins ◽  
Pain Syndrome ◽  
Bladder Pain Syndrome ◽  
Cellular Adhesion ◽  
Bladder Tissue ◽  
Bladder Pain ◽  
Adhesive Proteins

Abstract Background Interstitial cystitis/bladder pain syndrome is a bladder disease usually characterized by pain, urgency, and frequency. Interstitial cystitis is currently classified into two subtypes, with and without Hunner’s lesions. However, the underlying etiology of interstitial cystitis and its subtypes are largely unknown. Methods To better understand the biological changes in the bladder of interstitial cystitis/bladder pain syndrome patients, we directly analyzed bladder tissue of interstitial cystitis patients, both those with Hunner’s lesions and those without. Proteins in the bladder biopsies were analyzed using nanoscale high-performance liquid chromatography-tandem mass spectrometry. Disease subgroups were compared and significantly expressed proteins were mapped using STRING to determine protein associations and functions. Results We found that patients with Hunner’s lesions had significant increases in inflammatory and endoplasmic reticulum stress proteins, with a decrease in cellular adhesive proteins, compared to patients without Hunner’s lesions. These patients also exhibited a decrease in proteins associated with the Rap1 signaling pathway, which regulates cell proliferation and wound healing. When comparing diseased and non-disease-apparent tissue in patients with Hunner’s lesions, diseased tissue exhibited a decrease in ubiquitination proteins. Conclusions In summary, there are significant differences in protein expression found in the bladders of interstitial cystitis patients with and without Hunner’s lesions, indicating a disturbance in proteins associated with cellular adhesion, proliferation, protein processing, and wound healing.

The investigation of the electrochemically supercapacitive performances of mesoporous CuCo2S4

RSC Advances ◽  
2016 ◽  
Vol 6 (87) ◽  
pp. 84236-84241 ◽  
Author(s):  
Yirong Zhu ◽  
Xiaobo Ji ◽  
Han Chen ◽  
Liujiang Xi ◽  
Wenqiang Gong ◽  
...  
Keyword(s):  
High Performance ◽  
Electrode Materials ◽  
Electronic Conductivity ◽  
Electrochemical Activity ◽  
Single Component ◽  
Metal Sulfides ◽  
Ternary Metal ◽  
Ternary Metal Sulfides

Ternary metal sulfides have been regarded as a promising class of electrode materials for high-performance supercapacitors since they can offer higher electronic conductivity and higher electrochemical activity than single-component metal sulfides.

scholarly journals Copercolating Networks: An Approach for Realizing High-Performance Transparent Conductors using Multicomponent Nanostructured Networks

Nanophotonics ◽  
2016 ◽  
Vol 5 (1) ◽  
pp. 180-195 ◽  
Author(s):  
Suprem R. Das ◽  
Sajia Sadeque ◽  
Changwook Jeong ◽  
Ruiyi Chen ◽  
Muhammad A. Alam ◽  
...  
Keyword(s):  
Flexible Electronics ◽  
Indium Tin Oxide ◽  
High Performance ◽  
Silver Nanowires ◽  
Optical Transmittance ◽  
Single Component ◽  
Transparent Conductors ◽  
Hybrid Networks ◽  
Gold Nanowires ◽  
Metallic Nanowire Networks

Abstract Although transparent conductive oxides such as indium tin oxide (ITO) are widely employed as transparent conducting electrodes (TCEs) for applications such as touch screens and displays, new nanostructured TCEs are of interest for future applications, including emerging transparent and flexible electronics. A number of twodimensional networks of nanostructured elements have been reported, including metallic nanowire networks consisting of silver nanowires, metallic carbon nanotubes (m-CNTs), copper nanowires or gold nanowires, and metallic mesh structures. In these single-component systems, it has generally been difficult to achieve sheet resistances that are comparable to ITO at a given broadband optical transparency. A relatively new third category of TCEs consisting of networks of 1D-1D and 1D-2D nanocomposites (such as silver nanowires and CNTs, silver nanowires and polycrystalline graphene, silver nanowires and reduced graphene oxide) have demonstrated TCE performance comparable to, or better than, ITO. In such hybrid networks, copercolation between the two components can lead to relatively low sheet resistances at nanowire densities corresponding to high optical transmittance. This review provides an overview of reported hybrid networks, including a comparison of the performance regimes achievable with those of ITO and single-component nanostructured networks. The performance is compared to that expected from bulk thin films and analyzed in terms of the copercolation model. In addition, performance characteristics relevant for flexible and transparent applications are discussed. The new TCEs are promising, but significant work must be done to ensure earth abundance, stability, and reliability so that they can eventually replace traditional ITO-based transparent conductors.

scholarly journals Aqueous Extract of Brazilian Green Propolis: Primary Components, Evaluation of Inflammation and Wound Healing by Using Subcutaneous Implanted Sponges

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Sandra Aparecida Lima de Moura ◽  
Giuseppina Negri ◽  
Antônio Salatino ◽  
Luiza Dias da Cunha Lima ◽  
Luana Pereira Antunes Dourado ◽  
...  
Keyword(s):  
Wound Healing ◽  
Aqueous Extract ◽  
Mass Spectroscopy ◽  
High Performance ◽  
Healing Process ◽  
Treated Group ◽  
Progressive Increase ◽  
Health Condition ◽  
Wound Healing Process ◽  
Morphometric Analyses

Propolis is a chemically complex resinous bee product which has gained worldwide popularity as a means to improve health condition and prevent diseases. The main constituents of an aqueous extract of a sample of green propolis from Southeast Brazil were shown by high performance liquid chromatography/mass spectroscopy/mass spectroscopy to be mono- and di-O-caffeoylquinic acids; phenylpropanoids known as important constituents of alcohol extracts of green propolis, such as artepillin C and drupanin were also detected in low amounts in the aqueous extract. The anti-inflammatory activity of this extract was evaluated by determination of wound healing parameters. Female Swiss mice were implanted subcutaneously with polyesther-polyurethane sponge discs to induce wound healing responses, and administered orally with green propolis (500 mg kg−1). At 4, 7 and 14 days post-implantation, the fibrovascular stroma and deposition of extracellular matrix were evaluated by histopathologic and morphometric analyses. In the propolis-treated group at Days 4 and 7 the inflammatory process in the sponge was reduced in comparison with control. A progressive increase in cell influx and collagen deposition was observed in control and propolis-treated groups during the whole period. However, these effects were attenuated in the propolis-treated group at Days 4 and 7, indicating that key factors of the wound healing process are modulated by propolis constituents.

scholarly journals Distribution of an Analgesic Palmitoylethanolamide and Other N-Acylethanolamines in Human Placental Membranes

2021 ◽  
Author(s):  
Alzbeta Svobodova ◽  
Vladimir Vrkoslav ◽  
Ingrida Smeringaiova ◽  
Katerina Jirsova
Keyword(s):  
Wound Healing ◽  
Analgesic Effect ◽  
High Performance ◽  
Fold Increase ◽  
Mass Spectrometry Analysis ◽  
Neuroprotective Effects ◽  
Endogenous Fatty Acid ◽  
Spectrometry Analysis ◽  
Fatty Acid Amides ◽  
Anti Inflammatory

Abstract Human amniotic and amniochorionic membranes (AM, ACM) are the most often used grafts accelerating wound healing due to their anti-inflammatory, anti-microbial, anti-fibrotic, and analgesic properties. We assessed the distribution of endogenous fatty acid amides N-acylethanolamines (NAEs): palmitoylethanolamide (PEA), oleoylethanolamide (OEA) and anandamide (AEA) in placental tissues, as they could participate in wound healing properties of AM/ACM grafts. Ten placentas were collected after caesarean delivery. NAEs were detected using ultra-high-performance liquid chromatography-tandem mass spectrometry analysis in fresh samples of AM, ACM, placental disc, umbilical cord, umbilical serum and vernix caseosa), and decontaminated samples of AM and ACM. NAEs were present in all studied tissue types, with mean concentrations in fresh tissues ranging: 76 – 350 (PEA); 31 – 220 (OEA); 7 – 30 ng/g (AEA). The highest mean concentrations were found in AM (PEA: 350 ng/g) or placenta (OEA: 220 ng/g; AEA: 30 ng/g), respectively. Low levels of NAEs were found in serum and vernix. Decontamination of AM, but not ACM, induced a significant (3 – 3.5-fold) increase in the levels of NAEs. PEA is the first compound with direct analgesic effect detected in AM and ACM. We thus propose NAEs, especially PEA, as one of the possible factors responsible for the anti-hyperalgesic, anti-inflammatory and neuroprotective effects of AM/ACM grafts, stimulating their wound healing effect. The increase of NAE levels in AM and ACM after tissue decontamination indicates that tissue processing may play an important role in maintaining the analgesic effect.

scholarly journals Insight into the mechanism and outcoupling enhancement of excimer-associated white light generation

2016 ◽  
Vol 7 (6) ◽  
pp. 3556-3563 ◽  
Author(s):  
Ying-Hsiao Chen ◽  
Kuo-Chun Tang ◽  
Yi-Ting Chen ◽  
Jiun-Yi Shen ◽  
Yu-Sin Wu ◽  
...  
Keyword(s):  
White Light ◽  
High Performance ◽  
Single Component ◽  
White Light Generation ◽  
Light Generation ◽  
Excimer Formation ◽  
Fundamental Insight ◽  
Insight Into

Fundamental insight into excimer formation of Cz9PhAn, achieving a single-component, high-performance WOLED.

scholarly journals Compounds from Vernonia arborea Buch.-Ham. Inhibit Microbes that Impair Wound Healing

2021 ◽  
pp. 103-113
Author(s):  
Lalitha Vaidyanathan ◽  
T. Sivaswamy Lokeswari
Keyword(s):  
Wound Healing ◽  
High Performance ◽  
Healing Process ◽  
Bioactive Compound ◽  
Wound Management ◽  
Methanolic Extracts ◽  
Agar Well Diffusion Assay ◽  
Microtiter Assay ◽  
Layer Chromatography ◽  
Antimicrobial Potency

Aims: To identify the antimicrobial potency of the leaf fractions of Vernonia arborea against selected wound microbes viz., Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae and Stenotrophomonas maltophilia. Background: Wound healing is often delayed due to the presence of polymicrobial load, that have to be abolished to facilitate the healing process. A major class of antimicrobial phytocompound reported to occur in Vernonia arborea species include sesquiterpenes. Reports on the wound healing potency of V. arborea in wound models of Wistar rats however did not report antimicrobial activity of the aqueous or methanolic extracts. Methodology: The column fractions of the hexane leaf extract were tested against the selected strains by agar well diffusion assay and the zone of inhibition confirmed with TLC bioautography at specific Rf. The minimum inhibitory concentration (MIC) of the bioactive fractions was identified using resazurin microtiter assay (REMA) and the minimum bactericidal concentration (MBC) was determined. HPTLC quantification was also performed. Results: Out of the 30 pooled fractions, six showed antimicrobial potency against all the five tested wound microbes. The minimum inhibitory concentrations of these fractions were determined, ranging from 15.62 µg/mL to 500 µg/mL for the different microbes. Quantitative High-Performance Thin Layer Chromatography (HPTLC) revealed two compounds (a and b) in the bioactive fraction10 with yields of 633 mg (63%) and 97 mg (9.7%) per gram of the extract. Conclusion: The findings suggest the potential use of the bioactive compound in chronic infectious wound management therapy.

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