Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

AbstractBackground:Infertility has been associated with psychological distress, but whether these symptoms persist after achieving pregnancy via assisted reproductive technology (ART) remains unclear. We compared the prevalence of anxiety and depressive symptoms between women seeking for infertility treatment and women who conceived after ART or naturally.Methods:Four hundred and sixty-eight sub-fertile non-pregnant women, 2972 naturally pregnant women and 143 women pregnant after ART completed a questionnaire in this cross-sectional study. The Anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A≥8) and Edinburgh Postnatal Depression Scale (EPDS≥12) were used for assessing anxiety and depressive symptoms, respectively. Multivariate Poisson regression models with robust variance were applied to explore associations with anxiety and depressive symptoms.Results:The prevalence of anxiety and depressive symptoms among sub-fertile, non-pregnant women (57.6% and 15.7%, respectively) were significantly higher compared to women pregnant after ART (21.1% and 8.5%, respectively) and naturally pregnant women (18.8% and 10.3%, respectively). History of psychiatric diagnosis was identified as an independent risk factor for both anxiety and depressive symptoms. The presence of at least one unhealthy lifestyle behavior (daily tobacco smoking, weekly alcohol consumption, BMI≥25, and regular physical exercise < 2 h/week) was also associated with anxiety (Prevalence Ratio, PR: 1.24; 95%CI: 1.09–1.40) and depressive symptoms (PR: 1.25; 95%CI: 1.04–1.49).Conclusions:Women pregnant after ART showed no difference in anxiety and depressive symptoms compared to naturally pregnant women. However, early psychological counseling and management of unhealthy lifestyle behaviors for sub-fertile women may be advisable, particularly for women with a previous history of psychiatric diagnosis.

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Public Beliefs About the Helpfulness of Interventions for Depression: Effects on Actions Taken When Experiencing Anxiety and Depression Symptoms

Australian & New Zealand Journal of Psychiatry ◽

10.1080/j.1440-1614.2000.00761.x ◽

2000 ◽

Vol 34 (4) ◽

pp. 619-626 ◽

Cited By ~ 108

Author(s):

Anthony F. Jorm ◽

Jo Medway ◽

Helen Christensen ◽

Ailsa E. Korten ◽

Patricia A. Jacomb ◽

...

Keyword(s):

Mental Health ◽

Mental Health Professionals ◽

Health Professionals ◽

Psychiatric Symptoms ◽

Postal Survey ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Public Beliefs ◽

Actual Use ◽

History Of

Objective: Previous research has shown that the public have different beliefs to mental health professionals about the helpfulness of interventions for mental disorders. However, it is not known whether the public's beliefs actually influence their behaviour when they develop psychiatric symptoms. Method: A postal survey of 3109 Australian adults was used to assess beliefs about the helpfulness of a broad range of interventions for depression, as well as respondents' current level of anxiety and depression symptoms and any history of treated depression. A follow-up survey of 422 persons who had a high level of symptoms at baseline was conducted 6 months later. These people were asked which interventions they had used to reduce their symptoms. An analysis was carried out to see whether beliefs and other factors at baseline predicted subsequent use of interventions. Results: There were some major discrepancies between the ranking of interventions as likely to be helpful and the ranking of how frequently they were actually used. Interventions involving mental health professionals were often rated as likely to be helpful, but were rarely used in practice. Other simple, cheap and readily available interventions were used the most frequently, but were not the most likely to be rated as helpful. The most consistent predictors across all interventions used were gender, history of treatment, current symptoms and belief in a particular intervention. Of particular interest was the finding that beliefs in the helpfulness of antidepressants predicted their use. However, beliefs were not predictors of use for all interventions. Conclusions: Beliefs about the helpfulness of an intervention did not always predict actual use of that intervention, although beliefs did predict use of antidepressants. Therefore, campaigns that change public beliefs about effective treatments may also influence actual use of treatments. Interventions preferred by professionals are not frequently used at present. Most people with anxiety and depression symptoms rely primarily on simple self-help interventions, the effectiveness of which has been little researched.

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Post-Treatment Adverse Health Correlates among Prostate Cancer Survivors in a Sample of Men Residing in Atlantic Canada

Current Oncology ◽

10.3390/curroncol28040246 ◽

2021 ◽

Vol 28 (4) ◽

pp. 2812-2822

Author(s):

Gabriela Ilie ◽

Robert Rutledge ◽

Ellen Sweeney

Keyword(s):

Mental Health ◽

Prostate Cancer ◽

Large Population ◽

Predictor Variable ◽

Population Based ◽

Treatment Modalities ◽

Depression Symptoms ◽

Cross Sectional ◽

Care Plans ◽

History Of

Background: Recent large population-based studies have shed light on an association between prostate cancer (PCa) survivorship and mental health, which emerged when the comparison group was either men without a history of cancer or those with any other type of cancer except prostate. Here we examine the role of surgery alone, compared to other types of treatment modalities in this association in a population-based sample of men with prostate or other types of cancer. Methods: A cross-sectional analysis was conducted on a subsample of 632 male participants aged 36–69 from the 2009–2015 survey cycle of the Atlantic PATH cohort study. The primary outcomes were the presence of mild, moderate or severe depression or anxiety indicators and were assessed using the seven-item generalized anxiety disorder (GAD-7) scale and the nine-item Patient Health Questionnaire (PHQ-9), respectively. The presence of a lifetime history of PCa or other form of cancer (except PCa) was the main predictor variable and was assessed in cancer treatment modality (surgery or other types of treatment modalities) stratified analyses. Covariates included age, marital status, household income, comorbidity, and survivorship time. Results: The presence of depression in this sample was prevalent among 17.7% of men, and of anxiety among 9.3% of men. Survivors who were treated with surgery for their PCa diagnosis had 7.55 statistically significantly higher odds of screening positive for current depression symptoms compared with those of other forms of cancer in controlled analyses. These differences were not observed for anxiety. Conclusions: These findings emphasize the need for multidisciplinary survivorship care plans among PCa patients, especially those who undergo surgery. Targeted programming aimed at prioritizing and delivering comprehensive mental health support to PCa survivors early in the survivorship journey is justified.

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Genetic and environmental risk factors for depression assessed by subject-rated Symptom Check List versus Structured Clinical Interview

Psychological Medicine ◽

10.1017/s0033291701004755 ◽

2001 ◽

Vol 31 (8) ◽

pp. 1413-1423 ◽

Cited By ~ 30

Author(s):

D. L. FOLEY ◽

M. C. NEALE ◽

K. S. KENDLER

Keyword(s):

Risk Factors ◽

Major Depression ◽

Environmental Risk ◽

Genetic Risk ◽

Genetic Risk Factors ◽

Depression Symptoms ◽

Check List ◽

Lifetime History ◽

History Of ◽

Symptom Check List

Background. It is not known if a subject's characteristic level of self-rated depression symptoms index their genetic or environmental liability to major depressive disorder when measurement error and other occasion-specific influences are taken into account.Method. Monozygotic (N = 408) and dizygotic (N = 295) adult female twin pairs from a population-based registry were surveyed twice with an average follow-up interval of 61 months. At each occasion subjects completed a structured clinical interview (SCID) to assess lifetime history of major depression and the subject-rated Symptom Check List (SCL) to assess current level of depressive symptomatology. A bivariate measurement model was used to estimate the genetic and environmental correlations between liability to reliably diagnosed lifetime history of major depression and the characteristic or temporally stable SCL depression score.Results. The genetic and non-familial environmental correlation between liability to reliably diagnosed major depression and the characteristic level of SCL depression symptoms (and the proportion of variance shared between measures) is +0·70 and +0·24 respectively.Conclusions. When allowance is made for diagnostic unreliability and temporal fluctuations in the level of subject-rated symptoms, 70% of the variance in genetic risk factors and 24% of the variance in environmental risk factors is shared by a diagnosis of lifetime major depression and total SCL depression symptom score. SCL depression scores may therefore be a useful screening measure for many of the genetic risk factors which influence liability to major depression.

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Abstract 12613: Patient-reported Outcomes in a Multidisciplinary Electrophysiology-psychology Ventricular Arrhythmia Clinic

Circulation ◽

10.1161/circ.142.suppl_3.12613 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Andrew Nguyen ◽

John Dornblaser ◽

Andrew Gray ◽

Karen Paladino ◽

Adrienne Kovacs ◽

...

Keyword(s):

Health Status ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Clinical Settings ◽

Cardiac Device ◽

Patient Reported ◽

Item Level ◽

History Of ◽

Icd Shock ◽

Level Analysis

Background: Ventricular arrhythmias (VAs) and their treatment have been associated with psychological distress and poorer quality of life (QOL) in research studies. Patient-reported outcome (PRO) measures are beginning to be introduced in clinical settings and early experiences with their clinical utility warrant attention. We wanted to describe PROs of patients attending a multidisciplinary VA clinic in order to elucidate roles that PRO measures might have in clinical settings. Methods: In this retrospective study, we enrolled patients with history of sustained VA and/or ICD shock at their initial visit to a clinic staffed by an electrophysiologist and a psychologist. Patients completed several PRO measures including the following: anxiety and depression symptoms, visual analog scales for health status and QOL, cardiac device acceptance, ICD shock anxiety, and general cardiac anxiety. Here we report total scores for general PROs and item-level analysis of the three cardiac-specific measures. Results: A total of 57 patients (56 ±15 years; 84% male) were included; 39% had a history of sudden cardiac arrest, 70% had prior ICD shock and 44% had previously undergone VA ablation. Symptoms that exceeded clinical thresholds were common for anxiety (49%) and depression (20%). On 0-100 visual analogue scales, the mean rating for health status was 57 ± 16 and for QOL was 66 ± 18. Item-level analysis of cardiac-specific PROs revealed that between 40% and 50% of patients endorsed specific concerns regarding return to work, resumption of physical activities, and sexual relations (Table 1). Conclusion: Among patients attending a VA clinic, elevated symptoms of anxiety and depression were common and self-reported health status and QOL were low. Although PRO total scores provided general information, review at the individual item level provided critical information about potential sources of anxiety that can guide cardiologists during discussions with patients.

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The Role of Third Trimester Oxytocin Level in Predicting Postpartum Depression Symptoms among Jordanian Mothers.

10.21203/rs.3.rs-172460/v1 ◽

2021 ◽

Author(s):

Hasan RAWASHDEH ◽

Zahra ALALWANI ◽

Amer SINDIANI ◽

Rana ALODETALAH ◽

Mohammad ALQUDAH

Keyword(s):

Postpartum Depression ◽

Low Income ◽

Early Onset ◽

T Test ◽

Depression Symptoms ◽

Third Trimester ◽

Lifetime History ◽

History Of ◽

History Of Depression ◽

Oxytocin Level

Abstract Background: About one in five women suffer from postpartum depression, placing it the leading complication during childbirth. Oxytocin has been suggested to play a key role in modulating maternal behaviour and stress-related disorders. However, there is little evidence to support its role in predicting postpartum depression. Our aim is to investigate the relationship between serum oxytocin level in the third trimester and early-onset postpartum depression symptoms and whether oxytocin is capable of predicting postpartum depression symptoms.Methods: A total of 172 healthy pregnant women participated in this cross-sectional descriptive study. The serum oxytocin level was measured between 34 and 37 weeks. A validated Edinburgh Postnatal Depression Scale (EPDS) was used to assess symptoms of depression four to six weeks postpartum. Participants with EPDS scores of 13 or more were considered having depressive symptoms. SPSS version 23 was used for data analysis. Descriptive statistics were provided. Independent sample t-test and Pearson r were used to examine differences in depression scores between selected demographic, psychosocial, and clinical variables. The level of significance for all analyses was set at α=0.05.Results: 8% of participants have scored 13 or above at the EPDS. Pearson r indicated that there was no correlation between EPDS scores and oxytocin level r(170)=0.10, p=0.23. Furthermore, there was no correlation between EPDS scores and oxytocin level among women with a lifetime history of depression, r(43)= - 0.13, p=0.37. Independent t-test has shown that participants with low education, low income, previous history of depression, positive family history of depression, positive family issues and absent emotional family support have scored significantly higher on EPDS scores than their counterparts. The association with a previous lifetime history of depression was noticeable t(170)= - 4.40, p<0.001.Conclusions: There was no relation between late antenatal third trimester serum oxytocin level and early onset postpartum depression symptoms. Third trimester serum oxytocin level alone was not capable of predicting early onset postpartum depression.

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A-23 Mental Health Outcomes of Elite Athletes Following Sport Related Concussion

Archives of Clinical Neuropsychology ◽

10.1093/arclin/acaa036.23 ◽

2020 ◽

Vol 35 (5) ◽

pp. 619-619

Author(s):

C Hoyle ◽

M Mrazik ◽

D Naidu

Keyword(s):

Mental Health ◽

Return To Play ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Football Players ◽

Short Term ◽

Post Injury ◽

Time Points ◽

Healthy Control ◽

History Of

Abstract Objective Investigation of anxiety and depression symptoms at baseline and following sport related concussion in a population of professional and collegiate football players. Method A quasi-experimental prospective longitudinal design was implemented. Participants included 198 Canadian Football League and University of Alberta varsity football players at baseline. Additionally, this study tracked 13 concussed athletes, 12 orthopaedic control athletes, and 15 healthy control athletes over approximately a 2 month period. Statistical analysis included an ANOVA and repeated measures ANOVA to identify differences in mental health at baseline as well as after injury at 3 time points (24-48 hours post injury, asymptomatic, and 1 month post return to play). Results At baseline, players who had a history of 1 or more concussions reported a greater number of anxiety and depression symptoms in comparison to players who did not have a history of concussion (F(2, 197) = 66.75, (p =.000)). At the group level, there were no differences in anxiety and depression symptoms between players who sustained a concussion, orthoepic injury, or no injury across the four time points measured (depression (F(3, 58) = 1.05, (p =.404); anxiety (F(3, 58) = 1.65, (p =.151)). However, individuals who sustained a concussion displayed significant changes in symptoms of anxiety (F(3, 12) = 9.004, (p =.000)) and depression (F(3, 12) = 11.396, (p =.000)) over time. Specifically, concussed players reported an increase in anxiety related symptoms between baseline report and 24-48 hours post injury (p = .042), a decrease between 24-48 hours and 1 month post return to play (p = .002) and a decrease between asymptomatic and 1 month post return to play (p = .036) time points. Additionally, players who sustained a concussion reported a significant increase in depressive symptoms between 24-48 hours post injury and 1 month post return to play (p = .029) and a decrease between asymptomatic and 1 month post return to play (p = .014) time points. This change over time was not found in the orthopaedic injury (depression (F(3, 11) = 2.467, (p =.14); anxiety (F(3, 11) = 2.242, (p =.15)) or healthy control groups (depression; (F(3, 14) = 2.177, (p =.17); anxiety; F(3, 14) = 1.435, (p =.30)). Conclusions Results from this study suggest that a history of concussion impacts baseline self-report of anxiety and depression symptoms. Furthermore, players who sustained a concussion experienced subtle increases in anxiety and depressive symptoms in the short term and not in the long term. Players with who sustained an orthopaedic injury and healthy players did not show these changes in anxiety and depression symptom report. It appears that in this small sample concussion produced unique outcomes related to mental health functioning in the short term.

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Assessment of Current Mental Health Status in a Population-Based Sample of Canadian Men With and Without a History of Prostate Cancer Diagnosis: An Analysis of the Canadian Longitudinal Study on Aging (CLSA)

Frontiers in Psychiatry ◽

10.3389/fpsyt.2020.586260 ◽

2020 ◽

Vol 11 ◽

Author(s):

Louise Moodie ◽

Gabriela Ilie ◽

Robert Rutledge ◽

Pantelis Andreou ◽

Susan Kirkland

Keyword(s):

Mental Health ◽

Prostate Cancer ◽

Health Outcomes ◽

Cancer Diagnosis ◽

Smoking Status ◽

Population Based ◽

Mental Health Outcomes ◽

Prostate Cancer Diagnosis ◽

Lifetime History ◽

History Of

Background: Small-scale studies indicate an increase in mental health disorders among prostate cancer survivors compared to the general population, but large population-based data assessing this relationship are scarce. The present study examined the prevalence of lifetime history of prostate cancer in a cross-sectional sample of Canadian men and assessed the contribution of lifetime history of a prostate cancer diagnosis, multimorbidity, and current alcohol and smoking status to the association with current mental health outcomes in this population.Methods: The analytical sample included 25,183 men (aged 45 to 85 years old), who completed a survey as part of the Canadian Longitudinal Study on Aging (CLSA). The Center for Epidemiological Studies Depression Scale (CES-D10), Kessler's Psychological Distress Scale (K10), and self-reported mental health were mental health outcomes. Multiple logistic regression analyses, and controlling for the complexity of the design and covariates, evaluated the association between prostate cancer survivorship, multimorbidity, alcohol and smoking status, and current mental health outcomes.Results: The prevalence of lifetime history of prostate cancer diagnosis in this population-based sample of men was 4% (95% CI: 3.7, 4.4). Our results indicate statistically significantly higher odds of current psychological distress (aOR = 1.52, 95% CI: 1.09, 2.11) and screening positive for depression (aOR = 1.24; 95% CI: 1.02, 1.51) among survivors of prostate cancer, compared to men without a history of prostate cancer diagnosis in demographics controlled analyses. After addition of multimorbidity and substance use, the odds of screening positive for depression among survivors of prostate cancer are 1.32 (95% CI: 1.06, 1.64) higher compared to men who never had a history of prostate cancer diagnosis.Interpretation: Patient education and empowerment programs aimed at addressing concerns during the diagnosis and treatment and enhancing survivorship care plans by adding routine screening for mental distress to help survivors overcome poor mental health during the cancer survivorship journey, are warranted.

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Anxiety and depression levels of the general population during the rapid progressing stage in the coronavirus disease 2019 outbreak: a cross-sectional online investigation in China

BMJ Open ◽

10.1136/bmjopen-2021-050084 ◽

2021 ◽

Vol 11 (5) ◽

pp. e050084

Author(s):

Zeya Shi ◽

Yuelan Qin ◽

Sek Ying Chair ◽

Yanhui Liu ◽

Yu Tian ◽

...

Keyword(s):

Chinese Medicine ◽

General Population ◽

Psychological Health ◽

Political Party ◽

Associated Factors ◽

Anxiety And Depression ◽

Depression Symptoms ◽

Party Membership ◽

Cross Sectional ◽

History Of

ObjectiveThe outbreak of COVID-19 has major impacts on the psychological health of the public. This study aimed to investigate the anxiety and depression levels of the general population during the rapid progressing stage of COVID-19 pandemic in China and to explore the associated factors.Design and settingA cross-sectional online survey.Participants2651 Chinese people.MeasuresThe Hospital Anxiety and Depression Scale was used to measure their psychological health. A structured questionnaire collected possible associated factors, including sociodemographic characteristics, health information, contact history-related information, experience and perceptions, knowledge and education and adopted precautions. Multiple linear regression was conducted to explore the factors associated with anxiety and depression.ResultsThe mean score of anxiety and depression was 4.35 and 4.38, respectively. The rates of people with anxiety and depressive symptoms (with >7 score in the subscale) were 14.15% and 17.35%, respectively. Participants without political party membership, with contact history of COVID-19, going out or gathering, taking Chinese medicine herbs, being unsatisfied with current precautions, perceiving higher risks of infection, lower knowledge and poorer health presented higher anxiety and depression levels. Moreover, those who were females, married, lived alone and wore mask were more anxious; whereas people who were younger, experienced public health crisis, did not take precautions (regular work-rest, exercise) had higher depression level.ConclusionsDuring the rapid progressing stage of COVID-19 pandemic in China, one-seventh and one-sixth respondents presented anxiety and depression symptoms, respectively. The risk factors for anxiety and depression included the following: without political party membership, with contact history of COVID-19, going out or gathering, wearing masks, taking Chinese medicine herbs, being unsatisfied with current precautions, perceiving higher susceptibility, lower knowledge and poorer health status. Extensive information and psychological support should be provided to improve the mental health of the general population.

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An Examination of the Role of Socioeconomic Status in the Relationship between Depression and Prostate Cancer Survivorship in a Population-Based Sample of Men from Atlantic Canada

Oncology ◽

10.1159/000512444 ◽

2021 ◽

pp. 1-11

Author(s):

Gabriela Ilie ◽

Robert Rutledge ◽

Ellen Sweeney

Keyword(s):

Prostate Cancer ◽

Skin Cancer ◽

Cancer Survivorship ◽

Household Income ◽

Severe Depression ◽

Population Based ◽

Lifetime History ◽

History Of ◽

The Relationship

Objective: Prostate and skin cancer are among the most prevalent forms of cancer among men and have favorable survival rates compared to other, more aggressive forms of cancers. Recent studies have shown that the odds of depression among men with a lifetime history of prostate cancer are higher compared to men without a lifetime history of prostate cancer. Here we extend previous findings and examine the role of socioeconomic status in the relationship between depression and cancer survivorship status in a population-based sample of men from Atlantic Canada. Methods: A cross-sectional analysis was conducted on a subsample of 6,585 male participants aged 49–69 years from the 2009–2015 survey cycle of the Atlantic PATH study. The primary outcome was screening positive for mild, moderate or severe depression using the Patient Health Questionnaire (PHQ-9). The main predictor variable was cancer survivorship status (the presence of a lifetime history of prostate cancer, skin cancer, forms of cancer other than prostate or skin cancer, or absence of a lifetime cancer diagnosis). Covariates included age, education, marital status, household income, province, ethnicity, comorbidity, and survivorship time. Results: An estimated 14.7% of men in this sample screened positive for mild, moderate or severe depression. Men with a history of prostate cancer were 2.60 (95% CI: 1.02, 6.65) times more likely to screen positive for depression than men with a history of any other form of cancer. The odds ratios were 10.23 (95% CI: 2.82, 37.49) or 4.00 (95% CI: 1.20, 13.34) times higher for survivors of prostate or skin cancer who reported a low household income to screen positive for depression compared to men with a history of any other form of cancer and high household income. Conclusions: These results extend current evidence of the association between prostate cancer survivorship and depression compared with men who never had a history of cancer diagnosis by indicating that this association still stands when the survivors of prostate cancer are compared to survivors of any other form of cancer, and further indicates that this association is moderated by household income. The findings highlight the importance of delivering mental health screening and support to prostate cancer survivors during the cancer journey, especially those with low household incomes.

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