scholarly journals R&D, Innovative Collaborations and the Role of Public Policies

Author(s):  
Riccardo Crescenzi

Abstract R&D investments have the potential to boost innovation at the local level. However, this only happens where appropriate complementary skills and conditions are available locally to support knowledge generation and absorption. Where major R&D facilities are located in regions that lack the appropriate receptive environment the local mismatch between R&D and skilled labor can persistently hinder innovation and local spillovers. How can this be avoided? Public policies have an important role to play. They should facilitate the development of connections between local teams and those active in the research facility. The presence of star researchers in large research facilities might—for example—be a key factor to facilitate collaboration with local industrial partners offering significant opportunities for technological upgrading.

Publications ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 20
Author(s):  
Vasily Bunakov ◽  
Frances Madden

We present an information resource prototype that was developed by the FREYA project for the integration of a national e-thesis service and institutional repositories supported by a large national laboratory. The integration allows us to mutually enrich the metadata in the e-thesis service and institutional repositories with new entities and attributes, and can offer novel ways of reasoning over research outcomes that are supported by direct funding and funding-in-kind by large research facilities. The integrated information resource can be presented as a labeled-property graph for its exploration with a declarative query language and visualizations. We emphasize the role of persistent identifiers (PIDs), including for entities that are currently not necessarily or not consistently assigned PIDs.


2020 ◽  
Vol 2 (2) ◽  
pp. 69-82
Author(s):  
Didid Haryadi

The presence of the hijrah community in Indonesia directly resulted in the emergence of a new religious authority. Social media is a key factor in the massive campaign and regeneration carried out by the hijrah community. 'Terang Jakarta' and 'Shift Bandung' are two hijrah communities that have a very large number of congregations, especially on social media. This research attempts to answer the role of social media in shaping new patterns of new religious authority and to describe its relationship with traditional religious authority. Using a qualitative approach, this research finds that the formation of new religious authorities is more dominated by the prseference for preaching through social media, both by public figures and new religious teachers at the local level. These new religious authorities were actively involved in the hijrah community which they directly cultivated. Traditional religious authorities such as Nahdlatul Ulama (NU) and Muhammadiyah need to synergize programs with hijrah groups, especially in dakwah activities and religious moderation. This research considers that the Islamic Progressive group is an alternative movement capable of providing advocacy to all groups in Indonesia.


2016 ◽  
pp. 73-76
Author(s):  
B.M. Ventskivskiy ◽  
◽  
I.V. Poladych ◽  
S.O. Avramenko ◽  
◽  
...  

In recent years there has been an increase in the frequency of multiple pregnancies and the associated perinatal losses. It is a result of multiple pregnancy in ART refers to a high-risk gestation, at which premature births occur in 2 times more often than in singleton pregnancies. The objective: to determine the role of pro-inflammatory cytokines in the pathogenesis of premature labor in multiple pregnancy, as a result of assisted reproductive technology. Patients and methods. to determine the pro-inflammatory cytokines that all pregnant with bagtopliddyam held immunosorbent assay, defined concentrations of interleukin (IL) in serum and cervical mucus. Results. The analysis of the levels of pro-inflammatory cytokines (IL-1, IL-8) in the test environment, found high concentrations in the surveyed women with multiple pregnancy, due to the use of ART, compared with spontaneous multiple and singleton pregnancy. Increased concentration of proinflammatory cytokines in patients with multiple pregnancy by ART is associated with their synthesis at the system level, it stimulated foci of inflammation in the female genitals and extragenital localization. This correlates with the clinical data and statistical analysis, patients with multiple pregnancy as a result of ART had weighed infectious-inflammatory history. Conclusion. The study showed that elevated levels of proinflammatory cytokines in the systemic and local level in patients with multiple pregnancy due to ART, typical for women with miscarriage, because of the physiological course of pregnancy characterized by the predominance of anti-inflammatory cytokines that prevent rejection of the fetus as a foreign factor. Based on the data obtained proved the role of systemic inflammatory factors in the genesis of preterm labor in women with a multiple pregnancy, as a result of assisted reproductive technology. Key words: multiple pregnancy, assisted reproductive technology, premature birth, interleukine-1, interleukine-8.


2017 ◽  
pp. 163
Author(s):  
Nicolás Gómez Núñez

En tres breves capítulos, el artículo pone a disposición las ideas básicas que cruzan la reflexión sobre las actividades económicas que las personas realizan en condiciones de pobreza, destacándose la preocupación sobre si estos desempeños pueden constituirse en alternativas de crecimiento económico a nivel local o si ellas son actores que inciden en las políticas públicas que organizan los supuestos del desarrollo.Palabras clave Actividades Económicas Autogestionadas / Autonomía / Capacitación / Desarrollo Endógeno.Abstract:In three brief chapters, the article displays the basic ideas that intersect the reflection on the economic activities that people perform in conditions of poverty, standing out the concern whether these performances can constitute in alternatives of economic growth at the local level or whether they are activities that affect the public policies which organize the theories of development.Key words Self-managed economic activities / Autonomy / Training / Endogenous Development


2019 ◽  
pp. 3-9
Author(s):  
Krzysztof Rejman ◽  
Roman Fedan

Processes of the expected spatial socio-economic changes arise as a result of rational planning and continuation of development at regional and local level. A three-tier division ofthe local self-government creates opportunities for engagement of community in the rational planning model and local resource management, as well as usage of production factors; for socio-economic growth and improvement in the quality of life of the residents. The aim of the article is to show the functional structure and role of local government units in formation of regional and local policy toincrease economic growth, while maintaining the environmental protection requirements.


2021 ◽  
Vol 22 (15) ◽  
pp. 7765
Author(s):  
Youichirou Higashi ◽  
Takaaki Aratake ◽  
Takahiro Shimizu ◽  
Shogo Shimizu ◽  
Motoaki Saito

Stroke is a major cause of death worldwide, leading to serious disability. Post-ischemic injury, especially in the cerebral ischemia-prone hippocampus, is a serious problem, as it contributes to vascular dementia. Many studies have shown that in the hippocampus, ischemia/reperfusion induces neuronal death through oxidative stress and neuronal zinc (Zn2+) dyshomeostasis. Glutathione (GSH) plays an important role in protecting neurons against oxidative stress as a major intracellular antioxidant. In addition, the thiol group of GSH can function as a principal Zn2+ chelator for the maintenance of Zn2+ homeostasis in neurons. These lines of evidence suggest that neuronal GSH levels could be a key factor in post-stroke neuronal survival. In neurons, excitatory amino acid carrier 1 (EAAC1) is involved in the influx of cysteine, and intracellular cysteine is the rate-limiting substrate for the synthesis of GSH. Recently, several studies have indicated that cysteine uptake through EAAC1 suppresses ischemia-induced neuronal death via the promotion of hippocampal GSH synthesis in ischemic animal models. In this article, we aimed to review and describe the role of GSH in hippocampal neuroprotection after ischemia/reperfusion, focusing on EAAC1.


2021 ◽  
Vol 57 ◽  
pp. 165-181
Author(s):  
Aniello Ferraro ◽  
Massimiliano Cerciello ◽  
Massimiliano Agovino ◽  
Antonio Garofalo

2021 ◽  
Vol 13 (11) ◽  
pp. 5861
Author(s):  
Marianne Pedinotti-Castelle ◽  
Pierre-Olivier Pineau ◽  
Kathleen Vaillancourt ◽  
Ben Amor

Transportation is a key factor in the fight against climate change. Consumer behavior changes in transportation are underrepresented in energy policies, even if they could be essential to achieve the fixed GHG emission reduction targets. To help quantify the role of behaviors in energy transition and their implications on the dynamics of an energy system, this study is conducted using the North American TIMES Energy Model, adapted to Quebec (Canada). A behavioral disruption scenario (an increase in carpooling) is introduced in the model’s transportation sector and is compared to a massive electrification scenario. Our results highlight the fact that a behavioral disruption can lead to the same GHG emission reductions (65%) by 2050 as an electrification policy, while alleviating different efforts (such as additional electrical capacity and additional costs) associated with massive electrification. Moreover, the results are sensitive to behavior-related parameters, such as social discount rates and car lifetimes.


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