Stress Condition Modeling to Optimize Mud Weight Window for Efficient Drilling

2021 ◽  
pp. 77-89
Author(s):  
Dharmendra Kumar Gupta ◽  
Kamal Chandra Dani ◽  
Pushpa Sharma
Keyword(s):  
Stress Condition ◽  
Weight Window ◽  
Condition Modeling

Improved Burn-In Stress Methodology for Stress Uniformity

2018 ◽  
Author(s):  
Jungsuk Ko ◽  
Hoonchang yang ◽  
Hyungchae Jeon ◽  
Gyuyoung Nam ◽  
Youngseok Ryu ◽  
...  
Keyword(s):  
Temperature Stress ◽  
Stress Condition ◽  
Temperature Deviation ◽  
Stress Effects ◽  
Hot Temperature ◽  
Production Environments ◽  
Stress Environment ◽  
The Stability ◽  
Stress Uniformity ◽  
Stress Voltage

Abstract The necessity of hot temperature stress is widely recognized as the initial stress methodology to maintain the stability of products from infant defects in device [1, 2]. However, hot temperature stress has a disadvantage in terms of stress uniformity because temperature variation according to stress environment such as chamber, board, and tester accelerates different stress effects per chips. In addition, this stress condition can cause serious reliability problem in the mass production environments. Therefore, the stress temperature should be lowered to minimize the temperature deviation due to the production environments. The reduction of stress temperature cause the lack of stress amount, so optimized stress voltage and time to maintain the stress condition is required. In this study, various stress voltage and time with decreasing temperature were evaluated in consideration of lifetime that unit elements such transistors and capacitors did not degrade by any stress conditions. In addition, it was confirmed that stress uniformity can be improved in the stress condition obtained by the evaluation. Furthermore, the enhanced initial failure screen ability was proven with mass evaluations.

scholarly journals Interplay between Hypoxia and Extracellular Vesicles in Cancer and Inflammation

Biology ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 606
Author(s):  
Marta Venturella ◽  
Mattia Criscuoli ◽  
Fabio Carraro ◽  
Antonella Naldini ◽  
Davide Zocco
Keyword(s):  
Extracellular Vesicles ◽  
Stress Condition ◽  
Biological Functions ◽  
Severe Stress ◽  
Cancer And Inflammation

Hypoxia is a severe stress condition often observed in cancer and chronically inflamed cells and tissues. Extracellular vesicles play pivotal roles in these pathological processes and carry biomolecules that can be detected in many biofluids and may be exploited for diagnostic purposes. Several studies report the effects of hypoxia on extracellular vesicles’ release, molecular content, and biological functions in disease. This review summarizes the most recent findings in this field, highlighting the areas that warrant further investigation.

Effect of low power lasers on prokaryotic and eukaryotic cells under different stress condition: a review of the literature

2021 ◽  
Author(s):  
Adenilson de Souza da Fonseca ◽  
Larissa Alexsandra da Silva Neto Trajano ◽  
Eduardo Tavares Lima Trajano ◽  
Flavia de Paoli ◽  
Andre Luiz Mencalha
Keyword(s):  
Low Power ◽  
Stress Condition ◽  
Eukaryotic Cells ◽  
Review Of The Literature

Numerical solutions for strain-softening surrounding rock under three-dimensional principal stress condition

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Sheng Yu-ming ◽  
Li Chao ◽  
Xia Ming-yao ◽  
Zou Jin-feng
Keyword(s):  
Finite Element ◽  
Principal Stress ◽  
Stress Condition ◽  
Strain Softening ◽  
Numerical Solutions ◽  
Three Dimensional ◽  
Strength Criterion ◽  
Surrounding Rock ◽  
Flow Rule ◽  
Finite Element Software

Abstract In this study, elastoplastic model for the surrounding rock of axisymmetric circular tunnel is investigated under three-dimensional (3D) principal stress states. Novel numerical solutions for strain-softening surrounding rock were first proposed based on the modified 3D Hoek–Brown criterion and the associated flow rule. Under a 3D axisymmetric coordinate system, the distributions for stresses and displacement can be effectively determined on the basis of the redeveloped stress increment approach. The modified 3D Hoek–Brown strength criterion is also embedded into finite element software to characterize the yielding state of surrounding rock based on the modified yield surface and stress renewal algorithm. The Euler implicit constitutive integral algorithm and the consistent tangent stiffness matrix are reconstructed in terms of the 3D Hoek–Brown strength criterion. Therefore, the numerical solutions and finite element method (FEM) models for the deep buried tunnel under 3D principal stress condition are presented, so that the stability analysis of surrounding rock can be conducted in a direct and convenient way. The reliability of the proposed solutions was verified by comparison of the principal stresses obtained by the developed numerical approach and FEM model. From a practical point of view, the proposed approach can also be applied for the determination of ground response curve of the tunnel, which shows a satisfying accuracy compared with the measuring data.

scholarly journals Heat-tolerant hot pepper exhibits constant photosynthesis via increased transpiration rate, high proline content and fast recovery in heat stress condition

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sherzod Nigmatullayevich Rajametov ◽  
Eun Young Yang ◽  
Myeong Cheoul Cho ◽  
Soo Young Chae ◽  
Hyo Bong Jeong ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Heat Stress ◽  
Heat Tolerance ◽  
Transpiration Rate ◽  
Stress Condition ◽  
Proline Content ◽  
Hot Pepper ◽  
Fast Recovery ◽  
Heat Stress Condition ◽  
Heat Tolerant

AbstractUnderstanding the mechanism for heat tolerance is important for the hot pepper breeding program to develop heat-tolerant cultivars in changing climate. This study was conducted to investigate physiological and biochemical parameters related to heat tolerance and to determine leaf heat damage levels critical for selecting heat-tolerant genotypes. Seedlings of two commercial cultivars, heat-tolerant ‘NW Bigarim’ (NB) and susceptible ‘Chyung Yang’ (CY), were grown in 42 °C for ten days. Photosynthesis, electrolyte conductivity, proline content were measured among seedlings during heat treatment. Photosynthetic rate was significantly reduced in ‘CY’ but not in ‘NB’ seedlings in 42 °C. Stomatal conductivity and transpiration rate was significantly higher in ‘NB’ than ‘CY’. Proline content was also significantly higher in ‘NB’. After heat treatment, leaf heat damages were determined as 0, 25, 50 and 75% and plants with different leaf heat damages were moved to a glasshouse (30–32/22–24 °C in day/night). The growth and developmental parameters were investigated until 70 days. ‘NB’ was significantly affected by leaf heat damages only in fruit yield while ‘CY’ was in fruit set, number and yield. ‘NB’ showed fast recovery after heat stress compared to ‘CY’. These results suggest that constant photosynthetic rate via increased transpiration rate as well as high proline content in heat stress condition confer faster recovery from heat damage of heat-tolerant cultivars in seedlings stages.

scholarly journals Swallowing Gel for Patients with Dysphagia: A Novel Application of Chitosan

Gels ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. 108
Author(s):  
Tanikan Sangnim ◽  
Pornsak Sriamornsak ◽  
Inderbir Singh ◽  
Kampanart Huanbutta
Keyword(s):  
Molecular Weight ◽  
Carboxymethyl Cellulose ◽  
Stress Condition ◽  
Reference Product ◽  
The Elderly ◽  
Oral Drug ◽  
Disintegration Time ◽  
Tablet Disintegration ◽  
Tablet Dosage ◽  
Chitosan Gel

Dysphagia refers to difficulty swallowing certain foods, liquids, or pills. It is common among the elderly with chronic diseases who need to take drugs for long periods. Therefore, dysphagia might reduce compliance with oral drug administration in the aging population. Many pharmaceutical companies search for new products to serve as swallowing aids. Existing products are expensive and do not suit all geriatric patients. Therefore, this study aimed to develop and investigate pill swallowing aid gels prepared from carboxymethyl cellulose and chitosan. We formulated gels by dissolving different concentrations of carboxymethyl cellulose and low or high molecular weight chitosan in solvents to find appropriate gel rheology properties. We then added several portions of glycerin as the glidant of the formulation. We found that the optimized gel formulation was 6.25% (w/w) chitosan with a molecular weight of 80–120 kDa dissolved in 1.2% acetic acid and 4% (w/w) glycerin. The developed pill swallowing gel’s rheology was pseudoplastic with a viscosity of 73.74 ± 3.20 Pa⸱s. The developed chitosan gel had enhanced flow ability; it allowed the pill to cross a 300 mm tube within 6 s, while the reference product took 3 s. Even though the reference product could carry the pill in the tube faster, the chitosan gel better covered the pill, making it more convenient to use. Finally, using a theophylline tablet as a model tablet dosage form, we assessed the gel’s effect on drug disintegration and dissolution. The chitosan gel delayed the tablet disintegration time by about 3–7 min and slightly affected the theophylline dissolution rate. Lastly, all gels were physically stable after a month of storage in the stress condition. These results show the feasibility of manufacturing a chitosan gel usable as a pill swallowing gel for patients with dysphagia.

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