Pharmaceutical Industry and Clinical Medicine

2021 ◽  
pp. 137-176
Author(s):  
Sanjeev Kelkar
Keyword(s):  
Pharmaceutical Industry ◽  
Clinical Medicine

Conclusion

2021 ◽  
pp. 323-326
Author(s):  
Edward Shorter
Keyword(s):  
Pharmaceutical Industry ◽  
Clinical Psychiatry ◽  
Clinical Medicine ◽  
Treatment Practices

The psychopharmacologic model has led to the prescription of the wrong drugs for the wrong indications. This chapter cites Max Fink's judgment, which describes clinical psychiatry as an extraordinarily weak discipline that is split from clinical medicine, with its roots in unfounded psychological fantasies that disregard effective diagnostic and treatment practices. It also emphasizes how clinical psychiatry as a profession is unable to identify and treat most of the complaints of patients coming to the psychiatric clinics because it has floundered in its confusion of syndromes and studies of causes. The chapter analyzes how the psychopharmacologic model that started out with a promising future has become little more than an ad copy for the pharmaceutical industry. It mentions diseases that the system offers that are now considered wrong, because drugs cannot be discovered for ailments that don't exist.

A Review on “Phytochemical and Pharmacological activity of Bauhinia racemosa”

2021 ◽  
pp. 256-260
Author(s):  
Habeeba S Shaikh ◽  
Ravindra S Jadhav ◽  
Dattaprasad N Vikhe
Keyword(s):  
Pharmaceutical Industry ◽  
Antitumor Activity ◽  
Natural Product ◽  
Clinical Medicine ◽  
Higher Plants ◽  
Dominant Role ◽  
Stem Bark ◽  
Development Programs ◽  
Natural Sources ◽  
Ancient Times

Nature has provide a medicinal agents since, for thousands of years and a impressive number of modern medicines. The medicines are isolated from natural sources; several supported their use in ancient medication. Higher plants, as sources of medicinal compounds, have continuing to play a dominant role in the upkeep of human health since ancient times. Over five hundredth of all trendy clinical medicine area units of natural product origin and play an necessary role in drug development programs in the pharmaceutical industry. Bauhinia racemosa Lam. are the plant which is broadly distributed in tropical climate regions. Bauhinia species are flowering trees found in Caesalpiniaceae family. The root and stem bark fibers which possesses curative properties. Ethnopharmacologically, varied elements of the plant starting from the bark of the plant to the gum obtained has been used in diseases like, Diarrhea, dysentery, fever etc. B. racemosa have the different photochemical constituents like flavonoids, glycosides, phenols, saponins, and tannins. several pharmacological actions of the plant already proved, that embrace anti-microbial, anthelmintic, antitumor activity. This review focus on the pharmacological actions and phytoconstituets of Bauhinia racemosa.

Drug Induced Changes in Cell Organelles

1968 ◽  
Vol 26 ◽  
pp. 110-111
Author(s):  
Sarah A. Luse
Keyword(s):  
Clinical Medicine ◽  
Cell Organelles ◽  
Riboflavin Deficiency ◽  
Drug Induced ◽  
New Era ◽  
Health And Disease ◽  
In The Beginning ◽  
Cellular Pathology ◽  
Induced Changes ◽  
The Impact

In the mid-nineteenth century Virchow revolutionized pathology by introduction of the concept of “cellular pathology”. Today, a century later, this term has increasing significance in health and disease. We now are in the beginning of a new era in pathology, one which might well be termed “organelle pathology” or “subcellular pathology”. The impact of lysosomal diseases on clinical medicine exemplifies this role of pathology of organelles in elucidation of disease today.Another aspect of cell organelles of prime importance is their pathologic alteration by drugs, toxins, hormones and malnutrition. The sensitivity of cell organelles to minute alterations in their environment offers an accurate evaluation of the site of action of drugs in the study of both function and toxicity. Examples of mitochondrial lesions include the effect of DDD on the adrenal cortex, riboflavin deficiency on liver cells, elevated blood ammonia on the neuron and some 8-aminoquinolines on myocardium.

Methods and clinical applications in nuclear cardiology: a position statement

2002 ◽  
Vol 41 (01) ◽  
pp. 3-13 ◽  
Author(s):  
M. Schäfers
Keyword(s):  
Nuclear Cardiology ◽  
Clinical Medicine ◽  
Imaging Techniques ◽  
Cost Savings ◽  
Cost Benefit ◽  
Position Statement ◽  
Electron Beam Tomography ◽  
Partial Functions ◽  
Cost Benefit Ratio ◽  
Medicine Today

SummaryNuclear cardiological procedures have paved the way for non-invasive diagnostics of various partial functions of the heart. Many of these functions cannot be visualised for diagnosis by any other method (e. g. innervation). These techniques supplement morphological diagnosis with regard to treatment planning and monitoring. Furthermore, they possess considerable prognostic relevance, an increasingly important issue in clinical medicine today, not least in view of the cost-benefit ratio.Our current understanding shows that effective, targeted nuclear cardiology diagnosis – in particular for high-risk patients – can contribute toward cost savings while improving the quality of diagnostic and therapeutic measures.In the future, nuclear cardiology will have to withstand mounting competition from other imaging techniques (magnetic resonance imaging, electron beam tomography, multislice computed tomography). The continuing development of these methods increasingly enables measurement of functional aspects of the heart. Nuclear radiology methods will probably develop in the direction of molecular imaging.

Towards Systematization

1977 ◽  
Vol 16 (03) ◽  
pp. 125-130 ◽  
Author(s):  
P. L. Reichertz
Keyword(s):  
Clinical Medicine ◽  
Medical Science ◽  
User Involvement ◽  
Empirical Science ◽  
Target System ◽  
General Strategy ◽  
System Construction ◽  
Formal Approach ◽  
Methodology Development ◽  
Planning Development

Data processing has become an important tool in theoretical and clinical medicine. The main categories of applications are : information analysis, (bio)signal processing and the field of information logistics (information systems).The problems encountered lie in the discrepancy of the basic methods of a formal approach to an empirical science, the complexity of the target system and the system ecology, i.e. the involvement of the user and the system environment during system construction and utilization.Possible solutions to these problems are the application of system techniques, inductive planning, development of medical methodology, development of methods and techniques for user involvement and assessment of motivation and education and educational planning.The necessary general strategy in the development in medical informatics is seen in the continuing systematization of the theoretical and practical approach. It is estimated that this will eventually contribute to the systematization of medical science and practice.

On the Early Detection of Intravascular Coagulation

1972 ◽  
Vol 27 (03) ◽  
pp. 365-376 ◽  
Author(s):  
G Fedder ◽  
Elisabeth M. Prakke ◽  
J Vreeken
Keyword(s):  
Early Detection ◽  
Clinical Medicine ◽  
Blood Platelets ◽  
Factor V ◽  
Intravascular Coagulation ◽  
Fibrin Monomer ◽  
Gelation Test

SummarySince the conception of intravascular coagulation has been introduced in clinical medicine, the interest of clinicians in the early detection of this syndrome is continuously increasing. Therefore small amounts of thrombin and thromboplastin were infused into rabbits and special parameters, such as presence of an activated form of factor V and occurrence of a positive fibrin monomer test, were checked. As it turned out, activation of factor V (proaccelerin, accelerator globulin or AcG) was an earlier sign of intravascular coagulation than the appearance of a positive gelation test, which may occur without changes in fibrinogen or the number of blood platelets. These experiments could be of value for the early detection of intravascular coagulation in man.

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