Increased Trabecular Volumetric Bone Mass Density in Familial Hypocalciuric Hypercalcemia (FHH) Type 1: A Cross-Sectional Study

2014 ◽  
Vol 95 (2) ◽  
pp. 141-152 ◽  
Author(s):  
Niels Frederik Breum Jakobsen ◽  
Lars Rolighed ◽  
Emil Moser ◽  
Peter H. Nissen ◽  
Leif Mosekilde ◽  
...  
2020 ◽  
Vol 11 (4) ◽  
pp. 224
Author(s):  
MohitKishore Srivastava ◽  
Neetu Singh ◽  
Dileep Kumar ◽  
Ganesh Yadav ◽  
SudhirRamkishore Mishra ◽  
...  

2017 ◽  
Vol 33 (6) ◽  
pp. 267
Author(s):  
Widya Asih Lestari ◽  
Diah Mulyawati Utari

Dominant factors of hypercholesterolemia among pre-elderly in working area of Rangkapanjaya public health center in DepokPurposeThis study aimed to analyze the dominant factors of hypercholesterolemia among 45-59 years old elderly persons.MethodA cross-sectional study was conducted, involving 160 elderlies aged 45-49 years old in Rangkapanjaya. The data collection used Accutrend GC, BoneScan QUS, questionnaires, food recall, and Food Frequency Questionnaire. The data analysis used chi-square and logistic regression tests.ResultsThe factors most influencing hypercholesterolemia were vegetable intake frequency, body mass index, physical activity and bone mass density.ConclusionPeople with low total bone mass density have higher risk of getting hypercholesterolemia.


Author(s):  
Doley Lakhiprova ◽  
Sarma Tikendrajit ◽  
Baishya Pranabjyoti

Menopause is associated with a natural decline in estrogen, progesterone and testosterone. These leads to certain health concern signs and symptoms like vasomotor symptoms, urogenital atrophy, cardiovascular diseases, psychological changes, decrease bone mass density leading to osteoporosis and fracture, diminished of muscle mass and strength. In Ayurveda, Rajanivritti is the word found in relation with menopause. In female, ageing influences Rajanivritti where Dhatuksyaya has observed. There is limitation of presence of sign and symptoms of Rajanivritti, except the age which is mentioned as 50 years. Increased of Vata dosa, imbalance in Pitta and Kapha with subsequence Anulumakkshyay are observed in ageing, leading to abnormalities in all Dhatus specially Mamsa and Asthidhatu. In this work muscle strength, joint movement, bone mass density (BMD) has observed in 60 menopause women, where significant alteration noted in muscle strength of upper extremities and bone mass density (BMD) shows osteopenia.


2015 ◽  
Vol 7 (S1) ◽  
Author(s):  
Patrícia Ramos Guzatti ◽  
Amely PS Balthazar ◽  
Maria Heloisa Busi da Silva Canalli ◽  
Thais Fagnani Machado

Author(s):  
Dislene Nascimento dos Santos ◽  
Katia Nunes Sá ◽  
Fernanda C. Queirós ◽  
Alaí Barbosa Paixão ◽  
Kionna Oliveira Bernardes Santos ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Andrzej S. Januszewski ◽  
Yoon Hi Cho ◽  
Mugdha V. Joglekar ◽  
Ryan J. Farr ◽  
Emma S. Scott ◽  
...  

AbstractThe aim of this cross-sectional study was to compare plasma C-peptide presence and levels in people without diabetes (CON) and with Type 1 diabetes and relate C-peptide status to clinical factors. In a subset we evaluated 50 microRNAs (miRs) previously implicated in beta-cell death and associations with clinical status and C-peptide levels. Diabetes age of onset was stratified as adult (≥ 18 y.o) or childhood (< 18 y.o.), and diabetes duration was stratified as ≤ 10 years, 10–20 years and > 20 years. Plasma C-peptide was measured by ultrasensitive ELISA. Plasma miRs were quantified using TaqMan probe-primer mix on an OpenArray platform. C-peptide was detectable in 55.3% of (n = 349) people with diabetes, including 64.1% of adults and 34.0% of youth with diabetes, p < 0.0001 and in all (n = 253) participants without diabetes (CON). C-peptide levels, when detectable, were lower in the individuals with diabetes than in the CON group [median lower quartile (LQ)–upper quartile (UQ)] 5.0 (2.6–28.7) versus 650.9 (401.2–732.4) pmol/L respectively, p < 0.0001 and lower in childhood versus adult-onset diabetes [median (LQ–UQ) 4.2 (2.6–12.2) pmol/L vs. 8.0 (2.3–80.5) pmol/L, p = 0.02, respectively]. In the childhood-onset group more people with longer diabetes duration (> 20 years) had detectable C-peptide (60%) than in those with shorter diabetes duration (39%, p for trend < 0.05). Nine miRs significantly correlated with detectable C-peptide levels in people with diabetes and 16 miRs correlated with C-peptide levels in CON. Our cross-sectional study results are supportive of (a) greater beta-cell function loss in younger onset Type 1 diabetes; (b) persistent insulin secretion in adult-onset diabetes and possibly regenerative secretion in childhood-onset long diabetes duration; and (c) relationships of C-peptide levels with circulating miRs. Confirmatory clinical studies and related basic science studies are merited.


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