scholarly journals Incidence of surgical procedures for gastrointestinal complications after abdominal wall closure in patients with gastroschisis and omphalocele

Author(s):  
M. Haghshenas ◽  
U. Rolle ◽  
M. Hutter ◽  
T. M. Theilen

Abstract Purpose This study aims to define the extent of additional surgical procedures after abdominal wall closure (AWC) in patients with gastroschisis (GS) and omphalocele (OC) with special focus on gastrointestinal related operations. Methods A retrospective chart review was performed including all operations in GS and OC patients in the first year after AWC (2010–2019). The risk for surgery was calculated using the one-year cumulative incidence (CI). Results 33 GS patients (18 simple GS, 15 complex) and 24 OC patients (12 without (= OCL), 12 OC patients with liver protrusion (= OCL +)) were eligible for analysis. 43 secondary operations (23 in GS, 20 in OC patients) occurred after a median time of 84 days (16–824) in GS and 114.5 days (12–4368) in OC. Patients with complex versus simple GS had a significantly higher risk of undergoing a secondary operation (one-year CI 64.3% vs. 24.4%; p = 0.05). 86.5% of surgical procedures in complex GS and 36.3% in OCL + were related to gastrointestinal complications. Complex GS had a significantly higher risk for GI-related surgery than simple GS. Bowel obstruction was a risk factor for surgery in complex GS (one-year CI 35.7%). Conclusion Complex GS and OCL + patients had the highest risk of undergoing secondary operations, especially those with gastrointestinal complications.

2019 ◽  
pp. 80-85
Author(s):  
S. A. Berns ◽  
E. A. Schmidt ◽  
A. G. Neeshpapa ◽  
A. A. Potapenko ◽  
K. V. Smirnov ◽  
...  

Purpose: to identify the factors associated with the development of death events during the year follow-up after hospitalization for pulmonary embolism (PE). Materials and methods: 93 patients with PE discharged to the outpatient stage of observation were studied. 45 (61,6%) patients were female with an average age of 66 years. The examination of patients at the stage of inclusion in the study consisted of standard methods of examination for this pathology. The diagnosis was confirmed by multislice computed tomography. Follow-up was 12 months. Statistical analysis was performed using the MedCalc Version 16.2.1. Results: during the one-year follow-up period 62 (66,7%) patients with PE were alive but 11 patients (11,8%) died, and no information was obtained about 20 patients. The causes of death were as follows: the development of recurrent PE – 4 (36,4%) patients, cancer – 3 patients (27,3%), stroke – 2 (18,1%), one patient (9,1%) died due to severe heart failure and one – myocardial infarction. A comparative analysis in the groups of alive patients (n = 62) and patients with a fatal events (n = 11) showed that the dead patients were older (78 (68; 81) vs. 65 (49; 75) years; p = 0,003), had a higher PESI score (119,0 (99,7; 137,2) vs. 88,0 (68,0; 108,0); p = 0,016) and were less compliant to prolonged anticoagulant therapy during the one year of observation (45,5% of patients (n = 5) vs. 82,3% ( = 51); p = 0,015). The ROC curve determined that a high risk of death during the one year after PE is associated with age over 70 years (p = 0,0001) and more than 95 points by PESI in the hospital period (p = 0,0001). Conclusion: The death events were developed in 11,8% of cases in patients with pulmonary embolism during the first year of follow-up. The death outcomes were significantly associated with elderly age, intermediate and high risk by PESI in the hospital period and low compliance to anticoagulant therapy extended during the year after pulmonary embolism.


2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Charles Sing Lok Lau ◽  
Jeffrey Chi Wang Chan ◽  
Sophia Fei So ◽  
Orlando Chia Chieh Chan ◽  
Kenneth Kai Wang Li

Purpose. To compare the surgical outcome of combined phacoemulsification and endoscopic cyclophotocoagulation (phacoECP) versus combined phacoemulsification and mitomycin C-augmented trabeculectomy (phacoTbx) in patients with coexisting glaucoma and visually significant cataract. Methods. A retrospective review of 89 eyes of 89 patients who received phacoECP (N=49) and phacoTbx (N=40) was carried out at a tertiary eye center in Hong Kong. The minimum follow-up period was 6 months. Criterion of success was reduction of IOP at least 30% or absolute IOP of 15 mmHg or below without (complete success) or with (qualified success) antiglaucomatous medication. Results. PhacoTbx had more reduction of antiglaucomatous medication (4 vs 1, P<0.001). At postoperative year one, there was more IOP reduction for phacoTbx than phacoECP (8 mmHg vs 3 mmHg, P=0.012). The one-year complete success rate was also higher for phacoTbx (46.2% vs 8.2%, P<0.001), while qualified success was comparable between the 2 groups (74.4% vs 73.5%, P=0.925). Operation time was shorter for phacoECP (37 vs 73 minutes, P<0.001). The number of postoperative follow-up visits was less (6 vs 11.5, P<0.001) for phacoECP. Additional surgical procedures were more common in phacoTbx (55% vs 0%, P<0.001). There was no postoperative cystoid macula edema, hypotony, or endophthalmitis reported in both groups. Conclusions. PhacoECP is significantly less effective than phacoTbx in reduction of both IOP and number of antiglaucomatous medications for patients with medically uncontrolled glaucoma and cataract. Its complete success rate is also significantly lower than that of phacoTbx. With its comparable qualified success, shorter operation time, less number of postoperative visits, and secondary surgical intervention, phacoECP may still have a role in very selected cases.


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Isabel Pérez-Flores ◽  
Jose Luis Santiago ◽  
Natividad Calvo-Romero ◽  
Alberto Barrientos-Guzmán ◽  
Ana Isabel Sánchez-Fructuoso

It is well know that anti-HLA antibodies are an important obstacle in kidney transplantation. Our aim was to study the clinical impact of pretransplant donor specific anti-HLA antibodies (HLA-DSA), in highly sensitized (HS) patients. We analyzed retrospectively the day-of-transplant sera by Luminex Single Antigen Assay (LSA) in HS patients, and the results were correlated with episodes of humoral and cellular rejection as well as with graft and patient survival. All HS subjects received the same induction therapy and rejection episodes were biopsy proven. Thirteen patients (56.5%) preformed HLA-DSA, and we observed higher incidence of acute rejection in aforementioned patients than in the pre-transplant negatives DSA recipients (77% versus 30%, ). The one-year graft survival was significantly reduced in positive pre-transplant HLA-DSA patients (60% versus 100%, Breslow). The positive predicted value of HLA-DSA in relation to rejection reached 100% if patients lost their previous graft in the first year after transplant. Among anti-HLA antibodies present in patients before transplant, HLA-DSA were significantly associated with high risk of acute humoral and cellular rejection and reduced graft survival in posttransplant outcome. The negative impact of these antibodies was even higher when patients suffered an early loss of the previous transplant.


2018 ◽  
Vol 2 (2) ◽  
pp. 53-54 ◽  
Author(s):  
Carolyn A. Young ◽  
Linda L. Kinkel
Keyword(s):  
One Year ◽  

It is hard to believe that we have just celebrated the one-year anniversary of our first issue of the Phytobiomes journal! As we celebrate our first year, and as the term ‘phytobiome’ becomes more deeply embedded in our science, it is worth pausing to reflect on the impetus and science behind the phytobiome concept, and on the next steps for our journal.


2018 ◽  
Vol 5 (8) ◽  
pp. 2701
Author(s):  
Moharam Abdelsamie Mohamed Abd El Shahid ◽  
Fawzy Abo Bakre Mahmoud ◽  
Said Ebrahim Elmallah

Background: An efficient technique for abdominal wall closure should provide strength and be a barrier against infection. Method of closure and type of suture material are critical aspects of an effective abdominal wall closure after midline laparotomy. Dehiscence of abdominal wounds after closure is a serious complication especially in emergency laparotomies. Our study was done to know whether our method of abdominal closure was helpful in reducing incidence of wound dehiscence.Methods: Present study was carried out as a retrospective randomized clinical study in the department of general surgery, Menoufia University Hospitals for one year starting from March 2017 to March 2018. 168 patients had midline laparotomies (either elective or emergent) for inflammatory, traumatic or neoplastic indications.Results: In present study for this new technique of abdominal wall closure after midline laparotomies, wound infection was noticed in 12/168 (7.2%) cases and 2/168 (1.2%) patients developed wound dehiscence.Conclusions: Present study demonstrates that our new technique (Moharam Repair) of abdominal wall closure after midline laparotomies) is efficient in reducing post-operative wound dehiscence (burst abdomen). So, this technique is applicable, safe, and can minimize morbidities and mortalities related to wound dehiscence (as a short-term complication) after midline exploratory laparotomies (MEL).


2021 ◽  
Vol 11 (9) ◽  
pp. 3756
Author(s):  
Axel Dabbous-Wach ◽  
Margherita Rodolfi ◽  
Julien Paolini ◽  
Jean Costa ◽  
Tommaso Ganino

Hops (Humulus lupulus L.) is a species that grows spontaneously in Corsica, but the characterization of this species in this territory has not yet been investigated. The main objectives of this study are to explore the features of wild hops from Corsica and to determine the effect of the island terroir on some cultivars in the first year of growth. A multidisciplinary approach consisting of the genetic analysis, morphological comparison and chemical characterization of essential oils was carried out on four wild Corsican hops and three hop cultivars grown in Tettnang, Germany and Corsica, France. The morphological and GC-MS analysis of Corsican wild hops, set cluster coastal samples apart from the one far from the coast. This dissimilarity is supported by the SSR analysis by two of the three coastal accessions. The genetics demonstrate a proximity between the European noble cultivar Tettnanger and the mountain Corsican wild hop from Corte. The morphological comparison between German hops cultivated in Tettnang and in Corsican soil, and the GC-MS characterization of their essential oils’ chemical profiles, show different features between year 0 and year +1 for each sample. This multidisciplinary approach highlights an acclimatization of hop cultivars to the Corsican terroir one year after planting.


PEDIATRICS ◽  
1951 ◽  
Vol 7 (5) ◽  
pp. 731-731
Author(s):  
E. H. WATSON

George Wheatley's letter reminding us of the frightful toll of child life exacted by accidents prompts me to mention a practice I have tried to make routine. Probably many other Academy members have done about the same. The one year check-up, practically universally practiced by pediatricians, is a strategic time to bring up the danger of accidents which are so frequent in the preschool period. Before giving the routine booster of triple vaccine and tuberculin test, I like to make a point of reminding the mother that her child has safely passed one of the most dangerous periods of life—the first year. I believe it impresses the mother when I tell her that from now on the principal danger to her child is not poliomyelitis, not scarlet fever, diphtheria, whooping cough or pneumonia, but that if she should lose her child, it is more likely to be through accidental injury. She is reminded that many household cleaning powders and liquids may fatally poison her child or horribly disfigure him, that a few aspirin tablets or two or three of grandmother's heart pills might kill him. This statement is reinforced with the true statement that I have seen children die from exactly these causes.


PEDIATRICS ◽  
1953 ◽  
Vol 12 (1) ◽  
pp. 38-55

Two combinations of drugs were compared in a cooperative study of 32 children with acute hematogenous miliary tuberculosis treated at seven different pediatric centers under a common protocol. Eighteen children were given intramuscular streptomycin with oral para-aminosalicylic acid and promizole®; 14 children were given streptomycin and para-aminosalicylic acid without promizole®. A one year follow-up of this small group showed no significant differences in the results due to the use of promizole®. However, 5 of 10 children treated initially with a streptomycin dose of 20 mg./kg. intramuscularly twice a day were either dead or had developed meningitis, while only 2 of 22 children treated with a 50 mg. dose died, one of these having developed meningitis. Twenty-six of the original 32 patients were alive 12 months after the start of treatment. Relapse of miliary disease was not encountered during the first year of this study. The optimum duration of treatment is still uncertain. The combination of para-aminosalicylic acid with streptomycin may be assumed to delay the emergence of streptomycin-resistant organisms in miliary and meningeal diseases just as it does in pulmonary tuberculosis. Thus, a six month or even one year course of streptomycin can now be considered feasible. Although some patients may have been treated longer than necessary, the observation that three patients developed meningitis at 110, 125 and 130 days of study suggests that treatment should be relatively long. A child who survives miliary tuberculosis only to develop tuberculous meningitis has received little real benefit from therapy. As the over-all mortality in miliary tuberculosis is lowered, the prevention of meningitis in the survivors becomes an increasingly important goal. Disturbing side effects of promizole® therapy were less frequent among the patients reported here than among other reported groups. The daily dose, however, was small in comparison with the amounts recommended by Lincoln. Ninety-three children with tuberculous meningitis, 23 of whom also had miliary tuberculosis, were observed for a period of one year while under treatment with a combination of tuberculostatic agents. Half the patients were given intramuscular streptomycin, intrathecal streptomycin, and para-aminosalicylic acid and promizole® by mouth. The remainder received an identical regimen except that promizole® was omitted. Forty-two patients (45%) survived the first year; 24 of these had no serious sequelae from the disease. No differences were noted in the course of the disease among those who received promizole® and those who did not, and the one year survival rates in the two groups were practically identical. Revision of the streptomycin dosage, which took place after the study had been in progress seven months, produced results which appear to justify the change. An intramuscular streptomycin dose of 50 mg./kg. twice daily to a maximum of 1.5 gm. twice daily was apparently more effective than 20 mg./kg. twice daily. Lincoln whose results in childhood meningitis are the most successful yet reported and the British Medical Research Council both depend on a regimen which includes intrathecal streptomycin. The investigators in this study favor its use and had no unusual difficulty with it. Relapse occurred in eight children, all of whom survived the first year. A poorer prognosis was noted in infants, in nonwhites, and in patients with miliary tuberculosis. The most common toxic effects were due to streptomycin, which caused vestibular damage in a large number of patients, but the capacity of children to compensate for this dysfunction is so great that this risk is minor in the face of the otherwise hopeless outcome. Streptomycin may have been partially responsible for marked hearing loss in six. Para-aminosalicylic acid and promizole® act less rapidly than streptomycin. They are easily administered and rarely produce significant toxicity even when given over extended periods. They appear to reinforce the effect of streptomycin, and para-aminosalicylic acid at least postpones the emergence of streptomycin resistance. Their use appears to decrease the likelihood of relapse. Finally, their daily use at home maintains the patient's awareness that he requires prolonged medical supervision and brings him back for examination when his drug supply needs replenishing. The use of these drugs with streptomycin in tuberculous meningitis is recommended.


1961 ◽  
Vol 93 (9) ◽  
pp. 764-771 ◽  
Author(s):  
R. F. Shepherd

The spruce budworm, Choristoneura fumiferana (Clem.), is indigenous to most of the boreal forests in Canada and adjacent Eastern and Western United States. Throughout most of this range the budworm maintains a one-year cycle, overwintering as second instar larvae. In some mountainous areas of Alberta and British Columbia, a form of the budworm has a two-year cycle and over-winters as second instar larvae in the first year and as fourth instar larvae in the second year. The habitat temperatures of these two forms were investigated and related to rates of development in an attempt to discover the environmental factor which maintains the two-year cycle budworm as a distinct form even though it is geographically surrounded by the one-year cycle budworm.


2005 ◽  
Vol 11 (4) ◽  
pp. 671-705
Author(s):  
Daniel L. Seiler ◽  
Michel Duquette

This study covers the one-year period since the first election of the European Assembly by universal suffrage, the results of which were rather misleading. The authors attempt to elaborate a conceptual framework capable of analyzing empirically the programs and ideological stands of the parties in the Strasbourg Chamber as they have evolved since the election. As a point of reference, the analysis has recourse to three socio-political cleavages which were observable throughout late European history or tend to appear in the modem context of political life; these include the divisions between 1) "bourgeois" and working class parties; 2) europeanist versus nationalist parties, and 3) industralist (or productivist) as opposed to "ecological" party formations. A detailed examination of both the interventions of euro-deputies in Assembly debates, and data recorded in several interviews with some deputies during this first year of their mandate, reflects not only the existing constellations of power and party alliances within the Assembly that reaffirm themselves on specific issues, but also the potential coalitions which may arise due to the rapidly changing political scene. These new coalitions, which tend to form more easily among members of different parties who share common interests with regard to social and economic issues, may eventually serve to overcome the traditional ideological divisions among parties. In terms of the near future, it doesn't matter so much whether the Euro-right or the Euro-left will succeed in imposing its majority in the Assembly, but whether the European Parliament itself, as an institution, will be able to demonstrate that it can have an effective and more representative voice in the formulation of EEC policies.


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