Vitamin D deficiency and hyperparathyroidism in relation to ethnicity: a cross-sectional survey in healthy adults

2008 ◽  
Vol 48 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Rodrigo Moreno-Reyes ◽  
Yvon A. Carpentier ◽  
Marleen Boelaert ◽  
Khadija El Moumni ◽  
Ghislaine Dufourny ◽  
...  
PLoS ONE ◽  
2012 ◽  
Vol 7 (8) ◽  
pp. e43868 ◽  
Author(s):  
Stefanie Vandevijvere ◽  
Sihame Amsalkhir ◽  
Herman Van Oyen ◽  
Rodrigo Moreno-Reyes

2012 ◽  
Vol 166 (1) ◽  
pp. 77-85 ◽  
Author(s):  
David M Lee ◽  
Abdelouahid Tajar ◽  
Stephen R Pye ◽  
Steven Boonen ◽  
Dirk Vanderschueren ◽  
...  

ObjectiveInterrelationships between hormones of the hypothalamic–pituitary–testicular (HPT) axis, hypogonadism, vitamin D and seasonality remain poorly defined. We investigated whether HPT axis hormones and hypogonadism are associated with serum levels of 25-hydroxyvitamin D (25(OH)D) in men.Design and methodsCross-sectional survey of 3369 community-dwelling men aged 40–79 years in eight European centres. Testosterone (T), oestradiol (E2) and dihydrotestosterone were measured by gas chromatography–mass spectrometry; LH, FSH, sex hormone binding globulin (SHBG), 25(OH)D and parathyroid hormone by immunoassay. Free T was calculated from total T, SHBG and albumin. Gonadal status was categorised as eugonadal (normal T/LH), secondary (low T, low/normal LH), primary (low T, elevated LH) and compensated (normal T, elevated LH) hypogonadism. Associations of HPT axis hormones with 25(OH)D were examined using linear regression and hypogonadism with vitamin D using multinomial logistic regression.ResultsIn univariate analyses, free T levels were lower (P=0.02) and E2and LH levels were higher (P<0.05) in men with vitamin D deficiency (25(OH)D <50 nmol/l). 25(OH)D was positively associated with total and free T and negatively with E2and LH in age- and centre-adjusted linear regressions. After adjusting for health and lifestyle factors, no significant associations were observed between 25(OH)D and individual hormones of the HPT axis. However, vitamin D deficiency was significantly associated with compensated (relative risk ratio (RRR)=1.52,P=0.03) and secondary hypogonadism (RRR=1.16,P=0.05). Seasonal variation was only observed for 25(OH)D (P<0.001).ConclusionsSecondary and compensated hypogonadism were associated with vitamin D deficiency and the clinical significance of this relationship warrants further investigation.


2020 ◽  
Author(s):  
Negia Mohamed ◽  
Walid Al-Qerem ◽  
Ezeddin Gassar ◽  
Mohammad Hailat ◽  
Faiza Elhamdy ◽  
...  

Abstract Background: The message delivered to the public regarding vitamin D is unclear, and contradictory; particularly regarding sun exposure; previous studies in Jordan have revealed high prevalence of low vitamin D among university students. The aim of this study was to investigate university students’ knowledge, attitudes and practice regarding vitamin D.Method: A web-based cross-sectional survey completed by students at a Jordanian university in 2019. Binary logistic regression analysis was used to predict supplement use.Results: 496 students completed the questionnaire. The mean knowledge score was 31.3 (± 11.3) out of 100. Women had significantly higher beliefs that vitamin D deficiency is an escalating health issue (p<0.01). Negative practices regarding sun exposure was significantly higher in women than men (p<0.01). The majority of participants recognized that insufficient sun exposure was a cause of vitamin D deficiency, but 50.7 % avoid sun exposure, and 67.6% expose only their face and hands. The consumption of fortified foods (OR 3.59-;p<0.001) was the only studied variable associated with vitamin D consumption.Conclusion: There is a gap between knowledge, attitude, and practice regarding vitamin D which can be bridged by promoting Vitamin D related awareness.


2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Ellen Smith ◽  
Jessica Alvarez ◽  
Greg Martin ◽  
Susu Zughaier ◽  
Thomas Ziegler ◽  
...  

2020 ◽  
Vol 134 ◽  
pp. 110125
Author(s):  
Sun-Young Kim ◽  
Sang-Won Jeon ◽  
Weon-Jeong Lim ◽  
Kang-Seob Oh ◽  
Dong-Won Shin ◽  
...  

Author(s):  
Ramadevi Kundur ◽  
Ramaiah Itumalla ◽  
Eitimad Hashim Abdel-Rahman ◽  
Malak Saad Althawainy

Introduction: Vitamin D Deficiency (VDD) and several other metabolic factors are known to be involved in the aggravation of Osteoarthritis (OA). A better understanding of the role of these metabolic factors and diseases is required to alleviate the OA progression. Aim: To analyse the prevalence of VDD in OA patients and its correlation with co-morbidities such as diabetes, hypertension (HT), Cardiovascular Disease (CVD) and acidity and also to assess the effect of Body Mass Index (BMI) and increasing age on the developmental process of OA. Materials and Methods: A cross-sectional survey was undertaken during September 2018 to March 2019 in King Khaled, King Salman and Hail General Hospitals located in Ha’il province of Kingdom of Saudi Arabia (KSA). The study included 501 participants of OA patients that visited these hospitals. Data pertaining to the variables in this study such as diabetes, HT, cardiovascular problems, vitamin D and calcium deficiency, acidity and anthropometric details was obtained using a structured questionnaire. Data analysis was done using descriptive statistics and Pearson’s correlation with the statistical program SPSS version 21. Results: VDD, calcium deficiency and acidity were the most prevalent factors observed in the patients. Vitamin D and calcium deficiency was observed to be higher in females than males. VDD significantly correlated to diabetes, HT, acidity and age, both in females and males. Cardiovascular disease and BMI correlated with VDD only in males but not in females. BMI showed positive correlation with HT in males (p<0.01) but not females, and also correlated with age (p<0.01) irrespective of gender. Conclusion: The study concluded that VDD is more prevalent in females than males in Ha’il region. It is correlated to variables such as diabetes, HT, acidity, BMI and increasing age, which are identified as risk factors contributing to the progression of OA.


2020 ◽  
Vol 90 (3-4) ◽  
pp. 346-352
Author(s):  
Vincenzo Pilone ◽  
Salvatore Tramontano ◽  
Carmen Cutolo ◽  
Federica Marchese ◽  
Antonio Maria Pagano ◽  
...  

Abstract. We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index [BMI] of 34.9 ± 10.7 years, and 44.3 ± 6.99 kg/m2, respectively) met the inclusion criteria and were enrolled for data analysis. VDD (<19.9 ng/mL), severe VDD (<10 ng/mL), and vitamin D insufficiency (20–29.9 ng/mL) were present in 68.8 %, 12.5 %, and 31.2 % of patients, respectively. A significant inverse correlation was found between vitamin D levels and initial BMI, parathyroid hormone, and homeostatic model assessment of insulin resistance (r = −0.280, p < 0.05; r = −0.407, p = 0.038; r = −0.445, p = 0.005), respectively. VDD was significantly more prevalent in patients with higher BMI [−0.413 ± 0.12, CI95 % (−0.659; −0.167), p = 0.006], whereas no significant association between hypertension [−1.005 ± 1.65, CI95 % (−4.338; 2.326), p = 0.001], and diabetes type 2 (T2D) [−0.44 ± 2.20, CI95 % (−4.876; 3.986), p = 0.841] was found. We observed significant association between female sex and levels of vitamin D [6.69 ± 2.31, CI95 % (2.06; 11.33), p = 0.006]. The present study shows that in patients scheduled for BS, VDD deficiency is common and was associated with higher BMI, and female sex.


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