scholarly journals Association of hypogonadism with vitamin D status: the European Male Ageing Study

2012 ◽  
Vol 166 (1) ◽  
pp. 77-85 ◽  
Author(s):  
David M Lee ◽  
Abdelouahid Tajar ◽  
Stephen R Pye ◽  
Steven Boonen ◽  
Dirk Vanderschueren ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Multinomial Logistic Regression ◽  
Community Dwelling ◽  
Sex Hormone Binding Globulin ◽  
Gas Chromatography Mass Spectrometry ◽  
Relative Risk Ratio ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Hpt Axis

ObjectiveInterrelationships between hormones of the hypothalamic–pituitary–testicular (HPT) axis, hypogonadism, vitamin D and seasonality remain poorly defined. We investigated whether HPT axis hormones and hypogonadism are associated with serum levels of 25-hydroxyvitamin D (25(OH)D) in men.Design and methodsCross-sectional survey of 3369 community-dwelling men aged 40–79 years in eight European centres. Testosterone (T), oestradiol (E2) and dihydrotestosterone were measured by gas chromatography–mass spectrometry; LH, FSH, sex hormone binding globulin (SHBG), 25(OH)D and parathyroid hormone by immunoassay. Free T was calculated from total T, SHBG and albumin. Gonadal status was categorised as eugonadal (normal T/LH), secondary (low T, low/normal LH), primary (low T, elevated LH) and compensated (normal T, elevated LH) hypogonadism. Associations of HPT axis hormones with 25(OH)D were examined using linear regression and hypogonadism with vitamin D using multinomial logistic regression.ResultsIn univariate analyses, free T levels were lower (P=0.02) and E2and LH levels were higher (P<0.05) in men with vitamin D deficiency (25(OH)D <50 nmol/l). 25(OH)D was positively associated with total and free T and negatively with E2and LH in age- and centre-adjusted linear regressions. After adjusting for health and lifestyle factors, no significant associations were observed between 25(OH)D and individual hormones of the HPT axis. However, vitamin D deficiency was significantly associated with compensated (relative risk ratio (RRR)=1.52,P=0.03) and secondary hypogonadism (RRR=1.16,P=0.05). Seasonal variation was only observed for 25(OH)D (P<0.001).ConclusionsSecondary and compensated hypogonadism were associated with vitamin D deficiency and the clinical significance of this relationship warrants further investigation.

Vitamin D deficiency and hyperparathyroidism in relation to ethnicity: a cross-sectional survey in healthy adults

2008 ◽  
Vol 48 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Rodrigo Moreno-Reyes ◽  
Yvon A. Carpentier ◽  
Marleen Boelaert ◽  
Khadija El Moumni ◽  
Ghislaine Dufourny ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Healthy Adults ◽  
Cross Sectional Survey ◽  
Cross Sectional

scholarly journals High Prevalence of Vitamin D Deficiency in Pregnant Women: A National Cross-Sectional Survey

PLoS ONE ◽  
2012 ◽  
Vol 7 (8) ◽  
pp. e43868 ◽  
Author(s):  
Stefanie Vandevijvere ◽  
Sihame Amsalkhir ◽  
Herman Van Oyen ◽  
Rodrigo Moreno-Reyes
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
High Prevalence

scholarly journals Underweight and overweight/obesity among adults in Afghanistan: Prevalence and correlates from a national survey in 2018

2021 ◽  
Author(s):  
Supa Pengpid ◽  
Karl Peltzer
Keyword(s):  
Logistic Regression ◽  
Multinomial Logistic Regression ◽  
Normal Weight ◽  
Relative Risk Ratio ◽  
Adjusted Relative Risk ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Dual Burden ◽  
Male Sex

Abstract Background The study aimed to estimate the prevalence and correlates of underweight and overweight/obesity among adults in Afghanistan. Methods National cross-sectional survey data of 3,779 persons aged 18–69 years were analysed. Multinomial logistic regression was used to estimate factors associated with underweight and overweight/obesity relative to normal weight. Results In all, 7.8% of the study sample was underweight (BMI < 18.5 kg/m²), 49.5% had normal weight (BMI 18.5–24.9 kg/m²), 25.5% overweight (25.0-29.9 kg/m²), and 17.2% obesity. In adjusted multinomial logistic regression, factors negatively associated with underweight were male sex (Adjusted Relative Risk Ratio-ARRR: 0.55, Confidence Interval-CI: 0.32–0.95). Factors positively associated with overweight/obesity were aged 30–44 years (ARRR: 1.92, CI: 1.46–2.53) and aged 45–69 years (ARRR: 1.49, CI: 1.05–2.11) (compared to 18–29 years) (ARRR: 1.28, CI: 1.14–2.18), hypertension (ARRR: 2.69, CI: 1.88–3.85), type 2 diabetes (ARRR: 1.81, CI: 1.15–2.86), and raised cholesterol (ARRR: 2.04, CI: 1.41–2.95). Conclusion Almost one in ten adult respondents were underweight and more than two in five were overweight/obese, confirming a dual burden of malnutrition in Afghanistan.

scholarly journals The association between 25(OH)D levels, frailty status and adiposity indices in older adults

2018 ◽  
Author(s):  
Ana Rita Sousa-Santos ◽  
Cláudia Afonso ◽  
Alejandro Santos ◽  
Nuno Borges ◽  
Pedro Moreira ◽  
...  
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Multinomial Logistic Regression ◽  
Positive Association ◽  
Serum Levels ◽  
Shape Index ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Adiposity Indices

AbstractBackgroundVitamin D deficiency is common in older adults and has been linked with frailty and obesity, but it remains to be studied whether frail obese older adults are at higher risk of vitamin D deficiency. Therefore, the aim of this study is to explore the association between frailty, adiposity indices and serum 25(OH)D concentrations.Methods1447 individuals with 65 years or older, participating in a cross-sectional study (Nutrition UP 65). Frailty, according to Fried et al., body mass index (BMI), waist circumference (WC), body roundness index (BRI) and body shape index (ABSI) were evaluated. A stepwise multinomial logistic regression was carried out to quantify the association between 25(OH)D quartiles and independent variables.ResultsMedian 25(OH)D levels were lower in individuals presenting both frailty and obesity (p<0.001). In the multivariate analysis, pre-frailty (OR 2.65; 95% CI 1.63-4.32) and frailty (OR 3.76; 95% CI 2.08-6.81) were associated with increased odds of lower 25(OH)D serum levels (first quartile). Regarding adiposity indices, obesity (OR 1.75; 95% CI 1.07-2.87) and the highest categories of WC (OR 3.46; 95% CI 1.95-6.15), BRI (OR 4.35; 95% CI 2.60-7.29) and ABSI (OR 3.17 95% CI 1.86-5.38) were directly associated with lower 25(OH)D serum levels (first quartile).ConclusionsA positive association between frailty or obesity and lower levels of vitamin D was found. Moreover, besides BMI and WC, other indicators of body adiposity, such as BRI and ABSI, were associated with lower 25(OH)D serum concentrations.

scholarly journals Overweight and Obesity Among Adults in Iraq: Prevalence and Correlates From a National Survey in 2015

2020 ◽  
Author(s):  
Supa Pengpid ◽  
Karl Peltzer
Keyword(s):  
Logistic Regression ◽  
Multinomial Logistic Regression ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
Relative Risk Ratio ◽  
Adjusted Relative Risk ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Adult Participants ◽  
Nationally Representative

The study aimed to estimate the prevalence and correlates of overweight and obesity among adults in Iraq. Data from a 2015 nationally representative cross-sectional survey of 3,916 persons 18 years and older were analysed that responded to a questionnaire, physical and biochemical measures. Multinomial logistic regression was utilized to predict determinants of overweight and obesity relative to under or normal weight. Results indicate that 3.6% of the participants were underweight (BMI &lt;18.5 kg/m&sup2;), 30.8% had normal weight (BMI 18.5-24.9 kg/m&sup2;), 31.8% were overweight (25.0-29.9 kg/m&sup2;), and 33.9% had obesity (BMI &ge; 30.0 kg/m&sup2;). In adjusted multinomial logistic regression, aged 40-49 years (Adjusted Relative Risk Ratio-ARRR: 4.47, Confidence Interval-CI: 3.39-5.91), urban residence (ARRR: 1.28, CI: 1.14-2.18), hypertension (ARRR: 3.13, CI: 2.36-4.17) were positively, and male sex (ARRR: 0.47, CI: 0.33-0.68), having more than primary education (ARRR: 0.69, CI: 0.50-0.94), and larger household size (&ge;5 members) (ARRR: 0.45, CI: 0.33-0.60) were negativey associated with obesity. About two in three adult participants were overweight/obese, and sociodemographic and health risk factors were found that can be utilized in targeting interventions.

scholarly journals Vitamin D deficiency is associated with increased risk of postural hypotension in older men: a cross-sectional analysis from The British Regional Heart Study

2020 ◽  
Vol 70 (suppl 1) ◽  
pp. bjgp20X711209
Author(s):  
Artaza Gilani ◽  
Sheena Ramsay ◽  
Paul Welsh ◽  
Olia Papacosta ◽  
Lucy Lennon ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vitamin D ◽  
Parathyroid Hormone ◽  
Vitamin D Deficiency ◽  
Postural Hypotension ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Increased Risk ◽  
Sectional Analysis

BackgroundThere is growing interest in the role of vitamin D in extra-skeletal health, including postural hypotension. Postural hypotension is found in 1 in 5 community-dwelling adults aged 60 years and above. It increases risk of falls, fractures, cardiovascular disease and all-cause mortality. Better understanding of the aetiology of postural hypotension may help yield more effective treatment options than those that are currently available.AimThe aim of this study was to investigate the association between circulating vitamin D, parathyroid hormone and postural hypotension.MethodThis was a cross-sectional analysis of 3620 community-dwelling men living in the UK (mean age 68.6 years; standard deviation 5.5 years). Vitamin D status (nmol/L) was categorised as sufficient (≥50), insufficient (≥25 – <50), or deficient (<25). Parathyroid hormone levels were categorised by quintiles. Postural hypotension was defined by consensus criteria as a decrease in systolic blood pressure ≥20 mmHg and/or diastolic blood pressure ≥10 mmHg that occurred within three minutes of standing.ResultsCompared to sufficient levels of vitamin D, vitamin D deficiency increased risk of postural hypotension that specifically occurred within one minute of standing (OR 1.51, 95% CI = 1.06 to 2.15) in multinomial, multiple logistic regression. Neither vitamin D insufficiency, nor elevated parathyroid hormone, were associated with postural hypotension.ConclusionIn this study, vitamin D deficiency was associated with increased risk of postural hypotension. Further research may help clarify whether treating vitamin D deficiency can reduce the degree of postural hypotension, or if preventing the progression to vitamin D deficiency can reduce the incidence of postural hypotension.

scholarly journals Students’ ”D”ILEMMA: An Assessment of Knowledge, Attitudes and Practice Toward Vitamin D Among University Students

2020 ◽  
Author(s):  
Negia Mohamed ◽  
Walid Al-Qerem ◽  
Ezeddin Gassar ◽  
Mohammad Hailat ◽  
Faiza Elhamdy ◽  
...  
Keyword(s):  
Vitamin D ◽  
University Students ◽  
Vitamin D Deficiency ◽  
Binary Logistic Regression ◽  
Sun Exposure ◽  
Knowledge Score ◽  
Binary Logistic Regression Analysis ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Supplement Use

Abstract Background: The message delivered to the public regarding vitamin D is unclear, and contradictory; particularly regarding sun exposure; previous studies in Jordan have revealed high prevalence of low vitamin D among university students. The aim of this study was to investigate university students’ knowledge, attitudes and practice regarding vitamin D.Method: A web-based cross-sectional survey completed by students at a Jordanian university in 2019. Binary logistic regression analysis was used to predict supplement use.Results: 496 students completed the questionnaire. The mean knowledge score was 31.3 (± 11.3) out of 100. Women had significantly higher beliefs that vitamin D deficiency is an escalating health issue (p<0.01). Negative practices regarding sun exposure was significantly higher in women than men (p<0.01). The majority of participants recognized that insufficient sun exposure was a cause of vitamin D deficiency, but 50.7 % avoid sun exposure, and 67.6% expose only their face and hands. The consumption of fortified foods (OR 3.59-;p<0.001) was the only studied variable associated with vitamin D consumption.Conclusion: There is a gap between knowledge, attitude, and practice regarding vitamin D which can be bridged by promoting Vitamin D related awareness.

scholarly journals Vitamin D Deficiency in Lebanese Adults: Prevalence and Predictors from a Cross-Sectional Community-Based Study

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Asma Arabi ◽  
Nariman Chamoun ◽  
Mona P. Nasrallah ◽  
Hani M. Tamim
Keyword(s):  
Vitamin D ◽  
Alcohol Consumption ◽  
Serum Creatinine ◽  
Vitamin D Deficiency ◽  
Middle Eastern ◽  
Serum Vitamin ◽  
Community Dwelling ◽  
Cluster Sampling ◽  
Cross Sectional ◽  
Serum Vitamin D

Background/Objectives. The prevalence of vitamin D deficiency in the Middle Eastern population remains among the highest in the world, despite the region enjoying sunlight most days of the year. This study aimed at assessing the status of serum vitamin D and determining factors associated with vitamin D deficiency among community-dwelling adults residing in Greater Beirut, Lebanon. Methods. A random sample of Lebanese adults residing in the Greater Beirut area was selected based on area probability and multistage cluster sampling. Data from 446 participants (68% females) with mean age 45.3 ± 15 years were used for the analyses. Participants were recruited between March and May. Serum 25-hydroxyvitamin D levels were measured using electrochemiluminescent immunoassay. Results. Vitamin D deficiency was highly prevalent whether using the cutoff of 50 nmol/L or using the more conservative cutoff of 30 nmol/L; more specifically, 71.9% and 39.1% of the study population were deficient using the above cutoffs, respectively In the bivariate analyses, gender, BMI and body fat mass, socioeconomic factors (income and education level), alcohol consumption, dietary intake of fat and of vitamin D, serum LDL-cholesterol, and serum creatinine were all associated with vitamin D status. After adjustment for multiple covariates, age, income, alcohol consumption, and serum creatinine were independent predictors of vitamin D deficiency. Conclusion. Vitamin D deficiency is highly prevalent in Lebanon. Preventive measures should target the modifiable risk factors.

scholarly journals Overweight and Obesity among Adults in Iraq: Prevalence and Correlates from a National Survey in 2015

2021 ◽  
Vol 18 (8) ◽  
pp. 4198
Author(s):  
Supa Pengpid ◽  
Karl Peltzer
Keyword(s):  
Logistic Regression ◽  
Multinomial Logistic Regression ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
Relative Risk Ratio ◽  
Adjusted Relative Risk ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Adult Participants ◽  
Nationally Representative

This study aimed to estimate the prevalence and correlates of overweight and obesity among adults in Iraq. Data from a 2015 nationally representative cross-sectional survey of 3916 persons 18 years or older (M (median) age = 40 years, IQR (interquartile range) age = 29–52 years; men: M = 41 years, IQR = 29–54 years; women: M = 40 years, IQR = 30–51 years) who responded to a questionnaire, and physical and biochemical measures were analysed. Multinomial logistic regression was utilised to predict the determinants of overweight and obesity relative to under or normal weight. The results indicate that 3.6% of the participants were underweight (body mass index (BMI) <18.5 kg/m2), 30.8% had normal weight (BMI 18.5–24.9 kg/m2), 31.8% were overweight (25.0–29.9 kg/m2), and 33.9% had obesity (BMI ≥30.0 kg/m2). In the adjusted multinomial logistic regression, being aged 40–49 years (compared to 18–39 years old) (adjusted relative risk ratio (ARRR): 4.47, confidence interval (CI): 3.39–5.91), living in an urban residence (ARRR: 1.28, CI: 1.14–2.18), and having hypertension (ARRR: 3.13, CI: 2.36–4.17) were positively associated with obesity. Being male (ARRR: 0.47, CI: 0.33–0.68), having more than primary education (ARRR: 0.69, CI: 0.50–0.94), and having a larger household size (five members or more) (ARRR: 0.45, CI: 0.33–0.60) were negatively associated with obesity. Approximately two in three adult participants were overweight/obese, and sociodemographic and health risk factors were found that can be utilised in targeting interventions.

Sign in / Sign up

Export Citation Format

Share Document