Comparative effect of quail and chicken egg consumption on lipid profile, total proteins and blood parameters of male albino rats (Rattus norvegicus)

Datura metel is commonly found locally and it is readily available to the people, consequently, it is abused and deliberately used as poison. The aim of this study is to ascertain the effect of Datural metel through blood parameters and lipid profile when consumed through food intake using albino rat model. The leaves were extracted with ethanol and the phytochemical parameters determined. Different concentration of the extract were mixed with rat food and the food were fed to albino rats placed in four groups of five. The blood and lipid profile of rats were picked from each group determined at the end of week 1,2 and 3. Rats from each group was sacrificed and the blood was collected through cardiac puncture which was later analyzed for blood parameters and lipid profile. The results obtained from the first set of rats did not show any significant effect on the blood parameters and lipid profile, but the results obtained from subsequent sacrificed rats showed gradual increase in the values of the rate of haemoglobin (HB) 6.7 – 10G/DL, Red blood cells (RBC) 3.82 – 4.43 x 106µl and mean cell volume (MCV) 52.36 – 69.98FL. The results obtained for mean corpuscular haemoglobin concentration (MCHC) and mean corpuscular haemoglobin (MCH) and high density lipoproteins (HDL) are irregular. There is gradual decrease in the results obtained for low density lipoproteins (LDL) 27.2 – 20.2 mg/dl and cholesterol 79 -71 mg/dl. This study suggests that the concentration of ethanolic extracts of Datura metel leaves have different active components that have diverse revamping effects on the blood parameters and lipid profile based on concentration of the extracts and duration of intake of the extract. This invariably portray that presence of Datura metel in food can enhance the quality of the food in the body and also maintain good cardiovascular wellbeing based on its concentration and timeline of consumption.

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Influence of irisin on diet-induced metabolic syndrome in experimental rat model

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2020-0030 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Dalia Medhat ◽

Mona A. El-Bana ◽

Sherien M. El-Daly ◽

Magdi N. Ashour ◽

Tahany R. Elias ◽

...

Keyword(s):

Skeletal Muscle ◽

Lipid Profile ◽

Histopathological Examination ◽

Retinol Binding Protein ◽

Albino Rats ◽

Standard Diet ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Alcoholic Fatty Liver ◽

Kidney Functions

Abstract Objective To evaluate the influence of irisin on the experimental paradigm of non-alcoholic fatty liver (NAFL) as a part of MetS cluster. Methods Forty male albino rats were divided into four groups; normal control, standard diet + irisin, high carbohydrate and fat diet (HCHF), and HCHF + irisin. After the experimental period, levels of fasting blood sugar (FBS), insulin, lipid profile, kidney functions, salusin-alpha (Sal-α), adropin, and retinol-binding protein-4 (RBP-4) were evaluated. Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1α) expression in skeletal muscle was evaluated by quantitative real-time PCR. Aorta, liver, pancreas, and skeletal muscle tissue samples were prepared for histopathological examination. Results Rats administrated HCHF showed elevated levels of FBS, lipid profile, kidney functions, RBP-4, and downregulation of PGC-1α expression along with a decline in levels of insulin, Sal-α, and adropin while administration of irisin significantly attenuated these levels. Conclusions Irisin as based therapy could emerge as a new line of treatment against MetS and its related diseases.

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Comparative effect of Nauclea latifolia leaf fractions on blood glucose and lipid profile parameters of alloxan induced-diabetic rats

Journal of Medicinal Plants Research ◽

10.5897/jmpr2017.6355 ◽

2017 ◽

Vol 11 (24) ◽

pp. 387-392

Author(s):

Sylvester Effiong Grace ◽

Emmanuel Essien Grace

Keyword(s):

Blood Glucose ◽

Lipid Profile ◽

Diabetic Rats ◽

Comparative Effect ◽

Nauclea Latifolia

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Effect of Whole Quail (Coturnix japonica) Egg Consumption on some Reproductive Parameters and Lipid Profile of Male Albino Rat (Rattus norvegicus)

Notulae Scientia Biologicae ◽

10.15835/nsb9310093 ◽

2017 ◽

Vol 9 (3) ◽

pp. 315-320 ◽

Cited By ~ 1

Author(s):

Chidozie N. OKOYE ◽

Samuel O. EKERE ◽

Onyinyechukwu A. AGINA ◽

Ikechukwu J. UDEANI ◽

Chukwunonso K. EZEASOR

Keyword(s):

Lipid Profile ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Control Group ◽

Low Density ◽

Epididymal Sperm ◽

Treatment Groups ◽

Egg Consumption ◽

Group A ◽

The Mean

The present study evaluated the effect of whole egg consumption on the liver, testes, cauda epididymal sperm reserve and lipid profile of male rats. These evaluations were carried out on adult twenty (20) male albino rats, which were randomly selected into four groups of 5 rats each, designated groups A, B, C and D. Group A was the control group and received only equivalent volume of distilled water, while groups B, C and D received 0.25mg/kg, 0.5mg/kg; and 1.0mg/kg body weight of the quail egg respectively. Standard procedures were carried out in the tissue processing, cauda epididymal sperm reserve and in lipid profile determinations. On days 35 and 49, the mean serum total cholesterol value of group D was significantly lower than that of the control group. On day 35, the mean serum low density lipoprotein and high density lipoprotein (LDL and HDL cholesterol) values of all the treatment groups were significantly lower and higher than that of the control group, respectively. However, on days 49 and 63, the mean serum very low density lipoprotein (VLDL cholesterol) and triglyceride values of all the treatment groups were significantly higher than that of the control group. A significant increase in cadual epididymal sperm count (CESR) was recorded on day 63 at the mid and high doses. No obvious pathological lesions were observed in the histomorphology of the testes and liver when compared to the control. Therefore, whole quail egg consumption caused an increase in serum triglyceride and very low density lipoprotein concentration, and also improved fertility. In other words, prolonged consumption of quail egg should be done with caution as it may predispose one to cardiovascular disease.

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Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids

Memórias do Instituto Oswaldo Cruz ◽

10.1590/s0074-02761973000100005 ◽

1973 ◽

Vol 71 (1-2) ◽

pp. 87-93 ◽

Cited By ~ 2

Author(s):

Helly A. Lage ◽

Suelena A. Lage

Keyword(s):

Rattus Norvegicus ◽

Guinea Pigs ◽

Pneumocystis Carinii ◽

Albino Rats ◽

The Past ◽

Albino Mice

A survey was made on the incidence of Pneumocystis carinii in 361 rodents including sewer rats, albino rats, albino mice, guinea-pigs and rabbits. P. carinii was found in 4 of the 215 Rattus norvegicus examined (1,8%). These results accord with recent observations but disagree with investigations made by the researchers who first studied this parasite in the past when high indexes of infection were found. However, in 20 albino rats treated with corticosteroids (betamethazone) we found 8 positive (40%) and in 20 albino mice treated by the same way, 9 were positive for P. carinii (45%). These results confirm the opportunistic character of P. carinii in rodents already well demonstrated in man.

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