scholarly journals Effect of Whole Quail (Coturnix japonica) Egg Consumption on some Reproductive Parameters and Lipid Profile of Male Albino Rat (Rattus norvegicus)

2017 ◽  
Vol 9 (3) ◽  
pp. 315-320 ◽  
Author(s):  
Chidozie N. OKOYE ◽  
Samuel O. EKERE ◽  
Onyinyechukwu A. AGINA ◽  
Ikechukwu J. UDEANI ◽  
Chukwunonso K. EZEASOR

The present study evaluated the effect of whole egg consumption on the liver, testes, cauda epididymal sperm reserve and lipid profile of male rats. These evaluations were carried out on adult twenty (20) male albino rats, which were randomly selected into four groups of 5 rats each, designated groups A, B, C and D. Group A was the control group and received only equivalent volume of distilled water, while groups B, C and D received 0.25mg/kg, 0.5mg/kg; and 1.0mg/kg body weight of the quail egg respectively. Standard procedures were carried out in the tissue processing, cauda epididymal sperm reserve and in lipid profile determinations. On days 35 and 49, the mean serum total cholesterol value of group D was significantly lower than that of the control group. On day 35, the mean serum low density lipoprotein and high density lipoprotein (LDL and HDL cholesterol) values of all the treatment groups were significantly lower and higher than that of the control group, respectively. However, on days 49 and 63, the mean serum very low density lipoprotein (VLDL cholesterol) and triglyceride values of all the treatment groups were significantly higher than that of the control group. A significant increase in cadual epididymal sperm count (CESR) was recorded on day 63 at the mid and high doses. No obvious pathological lesions were observed in the histomorphology of the testes and liver when compared to the control. Therefore, whole quail egg consumption caused an increase in serum triglyceride and very low density lipoprotein concentration, and also improved fertility. In other words, prolonged consumption of quail egg should be done with caution as it may predispose one to cardiovascular disease.

2020 ◽  
Vol 22 (4) ◽  
pp. 238-242
Author(s):  
Sanita Kayastha ◽  
B Tiwari ◽  
R Subedi

The main objective of the study was to see the association of dyslipidemia in preeclampsia (PET) as compare to normotensive (NT) patients. It was a descriptive study done in Nepal Medical College Teaching Hospital Department of Obstetrics and Gynecology from April 2019 from April 2020. A total of 75 PET (test group) and 75 NT (control group) in their third trimester were included. Their fasting lipid profile was studied. It was found that triglyceride (TG) and very low density lipoprotein (VLDL) was significantly high among PET group as compared to that of NT patients. The mean TG of PET group was 266.11± 98.61 and the NT group was 187±58.56 (p=0.00) and the mean VLDL of PET group was 46.00±15.31 and NT group was 37.88±12.85 (p=0.001). On the other hand, the total cholesterol (TC), low density lipoprotein (LDL) and high density lipoprotein (HDL) were not significantly different in both the groups. It was also found that with the severity of the disease (Preeclampsia), the level of TG and VLDL increased significantly. Therefore, among the investigation done for PET, we should include lipid profile, especially the TG and VLDL. Furthermore, TG and VLDL should be measured serially (at least once a week) so as to predict the progress of PET and manage the patient accordingly.


Author(s):  
Eman A. Al-Rekabi ◽  
Dheyaa K. Alomer ◽  
Rana Talib Al-Muswie ◽  
Khalid G. Al-Fartosi

The present study aimed to investigate the effect of turmeric and ginger on lipid profile of male rats exposed to oxidative stress induced by hydrogen peroxide H2O2 at a concentration of 1% given with consumed drinking water to male rats. Methods: 200 mg/kg from turmeric and ginger were used, and the animals were treatment for 30 days. Results: the results showed a significant increase in cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipoprotein (VLDL), whereas it explained a significant decrease in high density lipoprotein (HDL) of male rats exposed to oxidative stress when compared with control group. the results showed a significant decrease in cholesterol, triglycerides, (LDL), (VLDL), whereas it explained a significant increase in (HDL) of rats treated with turmeric and ginger at dose 200 mg/kg when compared with male rats exposed to oxidative stress.


2021 ◽  
Vol 8 (32) ◽  
pp. 2980-2987
Author(s):  
Navjot Kaur Layal ◽  
Tejinder Sikri ◽  
Jaskiran Kaur ◽  
Jasmine Kaur ◽  
Hardeep Singh Deep

BACKGROUND Chronic kidney disease (CKD) includes a spectrum of different pathophysiology processes associated with abnormal kidney function, and a progressive decline in GFR. Progression of CKD is associated with having a number of complications, including thyroid dysfunction, dyslipidaemia, and cardiovascular diseases. METHODS The present study was conducted among 60 CKD patients (cases) and 60 healthy controls to compare their thyroid and lipid profile, who attended the Department of Medicine in SGRDIMSR, Sri Amritsar from January 2019 to December 2020.These 60 CKD patients were grouped as group A. Group A was further divided into various stages as per KIDGO staging according to GFR. 60 healthy individuals were taken as controls and were kept as Group B. Demographic features (age and sex) and medical history of diabetes mellitus, hypertension were noted and blood samples (5mL) were analysed for blood urea, serum creatinine, free triiodothyronine (T3), free thyroxine (T4), thyroid stimulating hormone (TSH), total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), very low density lipoprotein (VLDL) and triglycerides. RESULTS Thyroid dysfunction was observed in patients of CKD, the most common being overt hypothyroidism (56.6 %) followed by subclinical hypothyroidism (16.6 %), low T3 (15 %), and hyperthyroidism (1.6 %). Hypercholesterolemia, low HDL, elevated LDL, VLDL and triglyceride levels were observed in 74.9 %, 85.0 %, 38.3 %, 41.6 % and 76.6 % patients, respectively. Patients with CKD with 5 had significantly higher risk of having thyroid dysfunction and dyslipidaemia as compared to patients with stage 3 and 4. CONCLUSIONS Thyroid dysfunction and dyslipidaemia were common in patients with CKD. Prevalence of hypothyroidism, dyslipidaemia increases with progression of CKD. Hence early detection of thyroid dysfunction and dyslipidaemia is imperative to improve mortality and morbidity of CKD patients. KEYWORDS Chronic Kidney Disease, Dyslipidaemia, Thyroid Dysfunction


Author(s):  
Hymavathi K. Reddy ◽  
Vineela P. ◽  
Bhargavi M. Chowdary

Background: A comparative study of serum lipid profile and magnesium levels in normal pregnancy versus preeclampsia (PE).Methods: A prospective study done for 2 years (October 2014 to October 2016) in the Department of Obstetrics and Gynecology, Narayana medical college and hospital, a tertiary care centre, Nellore, Andhra Pradesh, India. A sample size of 200 pregnant women, recruited and divided into group A and B. group A being women with PE and group B is normal pregnant women.A10ml of venous blood was collected in the fasting state and serum collected from clotted blood to measure lipid profile, magnesium, Apo lipoprotein A-I and Apo lipoprotein B 100.Serum Lipid profile  measured by enzymatic method using commercially available kit Human (GmbH Germany) using humastar 600 chemistry analyzer (Human GmbH Germany). Serum magnesium measured by dye binding method using commercially available kit Human (GmbH Germany) using Humastar 600 chemistry analyzer (Human GmbH Germany). Serum ApoA-I and ApoB were measured by immune-turbidometry using commercial kits from Spinreact Spain. Urine albumin done by dipstick method.Results: Serum total cholesterol (TC), Triglyceride (TG), low density lipoprotein (LDL), very low-density lipoprotein (VLDL), Apo lipoprotein B 100 (Apo B100) were high and serum Magnesium, high density lipoprotein (HDL) and Apo lipoprotein A1(Apo A1) were low in the study group (group A) compared to controls (group B).Conclusions: Abnormal lipid profile (low HDL and increased TG concentration) and serum hypomagnesaemia may be contributing etiologies of preeclampsia, having good predictive value as a screening procedure for PE in high risk pregnant population.


2021 ◽  
Vol 8 (3) ◽  
pp. 030-039
Author(s):  
Funmilola Comfort Oladele ◽  
Bashirat Motunrayo Oluokun ◽  
Omotola Blessing Adam

This study was aimed at evaluating the effect of Parkia biglobosa seed on dexamethasone-treated pregnant rats. Locust bean seeds were purchased from an open market in Ado Ekiti, Nigeria. It was processed and ground into powder which was subsequently used in formulating feed for experimental animals. Fifteen female pregnant rats were divided in three groups of five each. Animals in group A were exposed to standard animal feed only. This served as the control group. Those in group B were exposed to animal feed mixed with locust beans + 0.3 mg/kg body weight of dexamethasone, while those in group C were exposed to animal feed mixed with locust beans. At the end of eight days treatment, animals were sacrificed and blood sample was collected into EDTA bottles and centrifuged. Plasma was separated and used for the determination of glucose and lipid profile. Exposure of animals to dexamethasone was observed to significantly (p<0.05) increased the concentration of plasma glucose concentration when compared with the control as well as animals treated with P. biglobosa only. Animals treated with dexamethasone along with P. biglobosa were observed to have higher concentrations of triglyceride, total cholesterol, low density lipoprotein (LDL) and very low density lipoprotein (VLDL) when compared with those in animals in the control group as well as those treated with P. biglobosa only. Observations from this study revealed that dexamethasone adversely perturbed and unhinged plasma glucose and lipid profile in female pregnant rats while P. biglobosa-formulated diet was observed to be a potent hypoglycemic and hypolipidemic agent.


2012 ◽  
Vol 17 (1) ◽  
pp. 37-40
Author(s):  
MKH Azad ◽  
SS Hussain ◽  
MBK Choudhury ◽  
FR Mowsumi

As dyslipidemia is responsible for remarkable cause of cardiovascular disease which is considered as the number one cause of death globally, this study was undertaken to evaluate the lipid profile status of offspring of dyslipidemic parents in comparison with the offspring of normolipidemic parents. In this study, carried out on 89 subjects, the mean total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-c) and low density lipoprotein (LDL-c) were 162.18 ± 20.97, 168.98 ± 33.51, 39.09 ± 3.62 and 90.41 ± 18.64 mg/dl respectively in adolescents with parental dyslipidemia and 158.38 ± 12.67, 157.22 ± 15.06, 40.51 ± 2.90 and 86.42 ± 12.39 mg/dl respectively in control adolescents. There were significant differences (p < 0.05) of TG and HDL-c between cases and controls where HDL-c choesterol was significantly lower in offspring of dyslipidemic parents then the offspring of normolipidemic parents. The findings of this study reflect the association of offspring dyslipidemia with parental dyslipidemia, probably due to some genetic predisposition. Offspring of dyslipidemic parents have higher levels of TC, TG, LDL-c and lower level of HDL-c compared to age and sex matched control subjects. DOI: http://dx.doi.org/10.3329/jdnmch.v17i1.12191 J. Dhaka National Med. Coll. Hos. 2011; 17 (01): 37-40


2012 ◽  
Vol 36 (0A) ◽  
pp. 181-186
Author(s):  
Suad A. Jashamy

A total of 15 Turkish- Awassi rams at ages ranged 2 - 2.5 years, and their weight rangedbetween 79.5 – 80.3 kg, Rams were randomly divided into 3 equal groups of 5 rams eachgroup. The first group were taken1000 while the second group were taken 2000 gaussmagnetic water, the third group were taken normal streaming water which is considered as a(control group). Blood sample were taken at the beginning of the experiment, and repeatedevery two weeks during the experimental period (four months). Results revealed that treatedthe rams with magnetically treated water resulted in significantly decreased (p<0.01) incholesterol (1.78-4.08), triglycerides (0.94-0.054), low density lipoprotein (LDL) (1.4-0.2),Very low density lipoprotein (VLDL) (1.87-0.14) and significant increase (p<0.01) in highdensity lipoprotein (HDL)(0.17-0.49) .It could be concluded that rams received magneticallytreated water resulted in significant improvement in level of lipid involved in this experiment.


1991 ◽  
Vol 37 (8) ◽  
pp. 1394-1397 ◽  
Author(s):  
M Sentí ◽  
J Pedro-Botet ◽  
X Nogués ◽  
J Rubiés-Prat

Abstract Values of low-density lipoprotein (LDL) cholesterol (C) according to the Friedewald formula (Clin Chem 1972;18:499-502) were compared with those obtained by lipoprotein fractionation in 98 healthy subjects (control group), 135 specimens from patients with peripheral vascular and cerebrovascular disease (atherosclerotic group), and 45 with chronic renal failure on hemodialysis (CRF group). All had concentrations of total cholesterol between 3.23 and 7.76 mmol/L (1.25-3.00 g/L) and triglycerides less than 3.39 mmol/L (less than 3.00 g/L). The percentage error of calculated LDL-C was 4% in controls with a cholesterol/triglycerides (C/TG) ratio for very-low-density lipoprotein (VLDL) of 0.20, but greater than 60% in those with a (C/TG)VLDL ratio of 0.40. The percentage of error in sera of patients with atherosclerosis and chronic renal failure was higher than in controls with a similar mean (C/TG)VLDL ratio. The percentage of error of calculated LDL-C increases progressively with the increase in the C/TG intermediate-density lipoprotein (IDL) ratio, both in controls and in the atherosclerotic and CRF groups. Similar findings are observed when the mean percentage of error of measured LDL-C is evaluated. The percentage of error from calculated LDL-C in the atherosclerotic and CRF groups is significantly lower than that obtained by comparison of LDL-C separated by ultracentrifugation when the "broad cut" LDL (IDL plus LDL, both by ultracentrifugation) was used. The high percentage of errors found in the groups of patients studied underlines the need for caution when assessing the reliability of the Friedewald formula, particularly in cases in which disturbances in IDL composition are suspected.


2012 ◽  
Vol 36 (0E) ◽  
pp. 120-126
Author(s):  
Khalisa Kadim Khudiar

The present study was undertaken to search out thebeneficial effect of magnetized water on serumantioxidant, lipid profile and total protein of adult male rabbits. Twenty adult male rabbits were randomly divided into two equal groups and were treated daily for 60 days as follows:Group C:Rabbits of this group were allowed to ad libitumsupplyofdrinking water (control group),Group MG:Rabbits of this group were allowed to ad libitum supply of magnetic water.Fasting blood (for 8-12 hrs) samples were drawn by cardiac puncture technique at different times 0, 30 and 60 days of experiment for measuring the following parameters. Serum glutathione concentration (GSH), lipid profile including serum triacylglycerol (TAG), total cholesterol - (TC), high density lipoprotein - cholesterol (HDL-C), low density lipoprotein - cholesterol (LDL-C) and very low density lipoprotein cholesterol - (VLDL-C), total serum protein concentrations (TSP). The result revealed that drinking of magnetic water had beneficial effect on some physiological aspects manifested by a significant elevation in serum GSH, HDL-C and total serum proteins concentration. In addition to significant suppression in serums TC, TAG, LDL-C, and VLDL-C concentrations .In conclusion the results of this study pointed to the prevalence of magnetic water upon normal drinking water in all measures issued.


2021 ◽  
Vol 19 (2) ◽  
pp. 39-43
Author(s):  
Monique Kafle ◽  
Madhu Gyawlee ◽  
Amit Amatya ◽  
Bhaskar Mohan Meher Kayastha ◽  
Smarika Upadhyaya

INTRODUCTION:  Psoriasis is a chronic inflammatory condition of skin which can be associated with other ailments including dyslipidemia which is an abnormal serum lipid profile. OBJECTIVE: The aim of present study was to determine correlation between dyslipidemia and Psoriasis of patients visiting the Out-patient Department of Patan Hospital METHODS: Ninety patients were selected for study. Among them 30 patients with psoriasis were taken as cases and 60 patients that matched for age and sex with Psoriasis patients were taken as controls. The lipid profile that comprised four parameters: serum High-density Lipoprotein, Low-density Lipoprotein, Total Cholesterol and Triglyceride were determined and compared for both case and control groups. RESULTS: More than 95% of the psoriatic patients had dyslipidemia. The odds of dyslipidemia among Psoriatic patients were 1.709 times higher compared to control group (p <0.001). Among the parameters, results showed High-density lipoprotein was significantly lower while Triglyceride was significantly higher among the cases compared to controls with p value of 0.012 and 0.001 respectively. The risk factors like smoking and alcohol were present in higher proportions among the patients with dyslipidemia but it failed to reach statistical significance. With increase in duration of Psoriasis and PASI scores, lipid parameters i.e., Total cholesterol, triglyceride and Low-density lipoprotein increased while High density lipoprotein decreased but this correlation was insignificant. CONCLUSION: This study showed Dyslipidemia is significantly higher among patients with Psoriasis especially lipid profile parameters Triglyceride and total cholesterol. Thus, timely screening and management of dyslipidemia among Psoriatic patients might be helpful in prevention of future cardiovascular events.


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