Collection and Characterisation of Malabar Tamarind [Garcinia cambogia (Gaertn.) Desr.]

2006 ◽  
Vol 53 (2) ◽  
pp. 401-406 ◽  
Author(s):  
Z. Abraham ◽  
S. K. Malik ◽  
Gangadhar Eashwar Rao ◽  
S. Lakshmi Narayanan ◽  
S. Biju
2014 ◽  
Vol 52 (9) ◽  
pp. 5906-5913 ◽  
Author(s):  
Tharachand Choppa ◽  
Chinnadurai Immanuel Selvaraj ◽  
Abraham Zachariah

2012 ◽  
Vol 506 ◽  
pp. 351-354 ◽  
Author(s):  
T. Phaechamud ◽  
K. Sarunyakasitrin ◽  
C. Choncheewa

Garcinia cambogia (Malabar tamarind) is a native plant of Southeast Asia which its dried rind has been extensively employed as an ingredient of the traditional food seasoning and dietary supplements for weight loss. This study aims to prepare the malabar tamarind fruit extract in form of stable foam mat. The development was performed using 1% w/v hydroxypropyl methylcellulose (Methocel K15M) and maltodextrin as foaming agent and foam carrier respectively. The contents of foaming agent were varied: 10, 20, 30, 40 and 50 percent and the contents of foam carrier were also varied: 20, 30, 40 and 50 percent. Highest content of foamed powder received when 50 percent of foaming agent was used and the content of foamed powder was much higher when maltodextrin was added. However, maltodextrin higher than 20 % can cause the disruption of foam formation and resulting in lower yield of foamed powder. Thus malabar tamarind instant powder could be prepared by foam-mat method using 50 percent of 1% methocel and 20 percent of maltodextrin as foaming agent and foam carrier, respectively. Foamed powder of malabar tamarind extract obtained after drying with hot air oven at 70 °C was bulky and stable.


2006 ◽  
Vol 11 (3) ◽  
pp. 210-217 ◽  
Author(s):  
Ju-Yeon Park ◽  
Hee-Sun Lee ◽  
Ju-Young Kim ◽  
Jin-Hee Lee ◽  
Kang-Pyo Lee ◽  
...  

2021 ◽  
Author(s):  
Michael K. Ibrahim ◽  
Marina Aboelsaad ◽  
Fatma Tony ◽  
Moustafa Sayed

Abstract Background: Obesity is a global concern, closely allied with somatic and psychosomatic disorders. Herbal drugs are available in modern medicine to treat obesity. Garcinia camobogia being used by so many people trying to lose weight produces various systemic side effects. The study was conducted to assess its effect on anxiety, sociability, and dopamine turnover in male mice. Methodology: Male Swiss albino mice of either were divided into three groups with seven mice in each group. Different groups were given distilled water (0.5ml p.o.) and Garcinia cambogia extract at two different doses (100mg/kg and 500 mg/kg p.o.). Effect of test drugs on anxiety was evaluated using open field test. Sociability and social novelty were evaluated using three chambers test. Results (mean ± standard deviation) were analyzed using one-way ANOVA test followed by Tukey’s test. Result: Garcinia cambogia extract significantly increased the time spent in the corners in the open field test, significantly reduced sociability and social novelty in the three chamber test, significantly reduced dopamine turnover and increased D2 receptor expression in ventral tegmental area. Conclusion: Garcinia cambogia extract have significant anxiogenic effect along with reduced sociability and social novelty in male mice. Moreover, these effects could be related to the altered dopamine turnover and D2 receptor expression in mice brain.


2018 ◽  
Vol 5 (1) ◽  
pp. 35
Author(s):  
Titilope Olanipekun ◽  
Valery Effoe ◽  
Ganiat Adeogun ◽  
Agniezka Gaertig ◽  
Myrtle White ◽  
...  

Exertional rhabdomyolysis from sickle cell trait has been documented. Also, cases of rhabdomyolysis from the use of weight loss supplements in the setting of sickle cell trait and exertion have been described. However, the role of sickle cell trait in non-exertional rhabdomyolysis is not clear. We present a case of severe non-exertional rhabdomyolysis from weight loss supplement in a patient with sickle cell trait.A 45-year-old African American female with sickle cell trait presented to the emergency department with two days history of fatigue and mild breathlessness. She also reported diarrhea and vomiting for five days before presentation. She admitted to taking Garcinia cambogia (a dietary supplement) for weight loss one week prior to the onset of symptoms. She denied alcohol or drug use, rigorous physical activity or trauma.She was dehydrated on examination. Laboratory values revealed markedly elevated serum creatine phosphokinase (CPK) and creatinine levels. Garcinia cambogia was discontinued and she was hydrated with intravenous fluids. Her CPK and creatinine levels significantly trended down and she was discharged home with no apparent sequelae.Our patient had multiple episodes of diarrhea and vomiting likely from the use of Garcinia cambogia. We believe she suffered non-exertional rhabdomyolysis from dehydration in the setting of sickle cell trait. Though dietary weight loss supplements are marketed as generally safe, this case suggests otherwise. We emphasize that clinicians routinely inquire about use of these supplements and provide appropriate counseling to patients on the adverse effects, especially among those with sickle cell trait.


2021 ◽  
Vol 15 (11) ◽  
pp. 2956-2957
Author(s):  
Gul Afshan ◽  
Ponum Mirani ◽  
Imtiaz Aslam ◽  
Sobia Ibrahim

Aim: Effects of available weight reducing drugs on the weights of a normal albino mice. Methodology: In this study, total 39 adult albino mice were used and were divided in three groups containing 13 animals in each. Group I served as control and was given 1 ml of distilled water once a day for 8 weeks. Group II and Group III served as experimental group and mice in these groups were given 0.5 mg of Slim Smart and Ultra Slim Plus drugs dissolved in 1 ml of distilled water respectively once a day for 8 weeks. To support these results weights of kidneys were also measured and relative tissue width index was calculated and compared with control group. Results: The weight of the animals increased in the experimental groups as compared to the control group. The overall difference for final weight among three groups was highly significant with p-value <0.01. When final weight compared group wise, the experimental groups had significantly higher weight as compared to control with p-values <0.01and 0.028 Conclusion: Both Ultra Slim Plus and Slim Smart drugs cause weight to increase in the individuals who are not obese and have BMI in normal range Keywords: Weight loss, Garcinia Cambodia, kidney, Albino mice


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