Engineering Escherichia coli for Fermentative Dihydrogen Production: Potential Role of NADH-Ferredoxin Oxidoreductase from the Hydrogenosome of Anaerobic Protozoa

2009 ◽  
Vol 153 (1-3) ◽  
pp. 21-33 ◽  
Author(s):  
Phi Minh Do ◽  
Alexander Angerhofer ◽  
Ivan Hrdy ◽  
Lucie Bardonova ◽  
Lonnie O. Ingram ◽  
...  
2017 ◽  
Vol 42 (1) ◽  
pp. 28-32
Author(s):  
K M Anwarul Haque ◽  
Kazuhiro Tateda ◽  
Yoshikazu Ishii ◽  
Qumrul Huda ◽  
Ruhul Amin Miah

Pathogens that carry antibacterial resistant genes represent a threat for failure of antibiotic therapy and are associated with high mortality, morbidity and expenses. In Bangladesh, although quinolone resistance in clinical infections has been reported, environmental influence to this resistance is poorly known. Thus, to examine the existence of quinolone resistant bacterial strains in surface water in Dhaka, the study was conducted during June 2012 to January 2014. Surface water samples from Dhaka city were screened and isolated quinolone resistant Pseudomonas putida, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Molecular and genetic analysis identified the resistant determinants in these isolates. The study suggests that potential role of water for the dissemination and transmission of resistant genes among microorganisms causing human and animal infections in Bangladesh.


1991 ◽  
Vol 10 (10) ◽  
pp. 746-751 ◽  
Author(s):  
CHRISTINE A. WANKE ◽  
JOHN B. SCHORLING ◽  
LEAH J. BARRETT ◽  
MARIA A. DESOUZA ◽  
RICHARD L. GUERRANT

2018 ◽  
Author(s):  
Ji Lu ◽  
Min Jin ◽  
Son Hoang Nguyen ◽  
Likai Mao ◽  
Jie Li ◽  
...  

ABSTRACTAntibiotic resistance poses a major threat to public health. Overuse and misuse of antibiotics are generally recognised as the key factors contributing to antibiotic resistance. However, whether non-antibiotic, anti-microbial (NAAM) chemicals can directly induce antibiotic resistance is unclear. We aim to investigate whether the exposure to a NAAM chemical triclosan (TCS) has an impact on inducing antibiotic resistance on Escherichia coli. Here, we report that at a concentration of 0.2 mg/L TCS induces multi-drug resistance in wild-type Escherichia coli after 30-day TCS exposure. The oxidative stress induced by TCS caused genetic mutations in genes such as fabI, frdD, marR, acrR and soxR, and subsequent up-regulation of the transcription of genes encoding beta-lactamase and multi-drug efflux pump, together with down-regulation of genes related to membrane permeability. The findings advance our understanding of the potential role of NAAM chemicals in the dissemination of antibiotic resistance in microbes, and highlights the need for controlling biocide applications.


2005 ◽  
Vol 71 (1) ◽  
pp. 326-330 ◽  
Author(s):  
Jeffrey T. LeJeune ◽  
Michael D. Kauffman

ABSTRACT Farm management practices that reduce the prevalence of food-borne pathogens in live animals are predicted to enhance food safety. To ascertain the potential role of livestock bedding in the ecology and epidemiology of Escherichia coli O157:H7 on farms, the survival of this pathogen in used-sand and used-sawdust dairy cow bedding was determined. Additionally, a longitudinal study of mature dairy cattle housed on 20 commercial dairy farms was conducted to compare the prevalence of E. coli O157:H7 in cattle bedded on sand to that in cattle bedded on sawdust. E. coli O157:H7 persisted at higher concentrations in used-sawdust bedding than in used-sand bedding. The overall average herd level prevalence (3.1 versus 1.4%) and the number of sample days yielding any tests of feces positive for E. coli O157:H7 (22 of 60 days versus 13 of 60 days) were higher in sawdust-bedded herds. The choice of bedding material used to house mature dairy cows may impact the prevalence of E. coli O157:H7 on dairy farms.


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