The impact of cichorium intybus L. On GDF-15 level in obese diabetic albino mice as compared with metformin effect

Author(s):  
Amira Kamel Eltokhy ◽  
Haidy Abdelaziz Khattab ◽  
Hanem Mohamed Rabah
2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Ashyana Kouser ◽  
Athar Ali Khan

This study was conducted to determine the impact of different concentrations (25, 37.5 and 50 mg kg-1 soil) of chromium (Cr) on growth, photosynthetic pigments, protein content, proline content, activities of antioxidant enzymes and seed yield of Cichorium intybus in a pot experiment. The results revealed that all the Cr treatments significantly (P </= 0.05) reduced the growth, photosynthetic pigments (chlorophyll a, chlorophyll b and total chlorophyll and carotenoids contents), protein content and seed yield in C. intybus. The activities of catalase (CAT), superoxide dismutase (SOD), peroxidase (POD) and proline content in C. intybus leaves increased significantly (P </= 0.05) with increasing levels of Cr treatments. Cr accumulation was found greater in the roots than in the shoots and enhanced with increasing Cr concentrations. Hence, C. intybus may serve as a bio-meter of Cr in Cr contaminated soils.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Muhammad Torequl Islam ◽  
Thoufiqul Alam Riaz ◽  
Seyed Abdulmajid Ayatollahi ◽  
Javad Sharifi-Rad

AbstractAnxiety disorders are general and psychological problems that are also linked to symptoms of depression. This study aimed to investigate the anxiolytic-like effects of Urena lobata L. (MEUL) methanolic extract in different behavioral paradigms in Swiss albino mice. For this, after an oral acute toxicity study, adult male mice were treated with MEUL (250 and 500 mg/kg, p.o.) and/or diazepam (2 mg/kg, i.p.), and subjected to a number of behavioral studies. In the open-field test, the number of square field cross, grooming, and rearing, was counted, while in the light/dark and swing test, the time spent in the dark portion and number of swings was calculated, respectively. Additionally, the phytochemical analysis was also done. Results reveal that the MEUL possesses alkaloids, glycosides, flavonoids, phenols, saponins, terpenes (including triterpenes), gums, and reducing sugars. MEUL showed a significant (p < 0.05) anxiolytic-like effect in experimental animals, where it’s dose-dependently modulated the test parameters in an open-field test. The MEUL also increased the light residence time and the number of swings in a dose-dependent manner. A dose of 500 mg/kg of MEUL caused the highest calming effect when combined with the experimental animals’ diazepam group. Taken together, findings expand an understanding of the impact of U. lobata on the central nervous system and show that this plant may be useful for the treatment of disorders associated with anxiety.


2015 ◽  
Vol 66 (2) ◽  
pp. 168 ◽  
Author(s):  
Julia M. Lee ◽  
Nivonne R. Hemmingson ◽  
Elena M. K. Minnee ◽  
Cameron E. F. Clark

Chicory (Cichorium intybus L.) and narrow-leaved plantain (Plantago lanceolata L.) are able to grow a large amount of high-quality summer feed. Limited information is available on the effect of grazing management on plantain, and no comparison been undertaken of modern chicory and plantain cultivars used in dairy production systems. This study determined the effect of defoliation interval (as determined by the extended leaf height, ELH) and residual height on the yield, nutritive characteristics and plant density of chicory and plantain over 18 months. Chicory leaf yield was reduced in swards defoliated at 150 mm ELH compared with those defoliated at 250, 350 or 550 mm (14.3 v. 17.5 t DM ha–1), and chicory stem yield was least in swards defoliated at 150 or 250 mm. Plantain swards defoliated at 350 or 450 mm ELH yielded more leaf than those defoliated at 150 or 250 mm (20.4 v. 16.7 t DM ha–1); however, stem yield also increased with increasing defoliation interval. Over all seasons, as defoliation interval increased, generally, neutral detergent fibre content increased and crude protein, ash and digestibility declined. Residual height had less of an effect on yield and nutritive characteristics than did defoliation interval. To maximise chicory leaf growth while minimising growth of lower quality stem, the optimal ELH over 18 months was 250 mm, or if the chicory was used only as a 9-month ‘summer’ crop, 350 mm. Recommendations for plantain are not as simple because longer defoliation intervals increase both leaf and stem yield and reduce nutritive value. Defoliating plantain swards at 250 mm ELH appeared to provide a balance between yield and nutritive value; however, further work is required to determine the impact of applying these recommendations on a dairy farm system.


2014 ◽  
Vol 11 (2) ◽  
pp. 913-919
Author(s):  
Baghdad Science Journal

the current study Included, evaluation the impact of Nitrofurantoin drug on liver in albino mice, 128 male albino mice have been used . Animals treared with (150,200 Mg/Kg) for 8 weeks . NFI caused histological changes in liver represented by , swelling of hepatocytes, disappearance of radial arrangement , vaculation of liver cells , increasing of kupffer cells and appearance of giant cells. NFT caused Congestion of blood vessels and infiltration of inflammatory cells in liver in all used concentrations.


2021 ◽  
Vol 121 (2) ◽  
pp. 21-32
Author(s):  
Susan Y. Jaconis ◽  
Theresa M. Culley ◽  
Timothy Keener ◽  
Alexandra M. Odom ◽  
Robert Elam ◽  
...  

Plants growing along roadways are often exposed to vehicle exhaust containing both particulate matter (PM) and various gases that could affect gas exchange and thus plant reproduction. To investigate effects of diesel exhaust exposure on plant ecophysiology, growth, and fecundity, individuals of soybean (Glycine max (L.) Merr.) and chicory (Cichorium intybus L.) were exposed to either exhaust from a diesel generator or ambient air. Exposure occurred daily over a 5-day period (beginning 18 June 2013) using open-top chambers in an agricultural field in southwestern Ohio, United States. Plants were evaluated at 3 times (before, directly after exposure, and following a 5.5-week post-treatment recovery period) for photosynthetic rate (A), stomatal conductance (g), water use efficiency (WUE), stomatal clogging due to PM deposition, and number of nodes. Aboveground biomass, fruit number, mean seed number, and seed mass were measured for soybean after the recovery period. In soybean, A minimally decreased with exposure to diesel exhaust (compared to the control), but an increase in g and a decrease in WUE were detected after the exhaust treatment. Chicory exhibited a relatively low increase in A after the treatment, but there were no clear differences in g or WUE. Growth and fecundity were similar among all soybean plants directly after treatment, but after 5.5 weeks plants exposed to diesel exhaust had increased vegetative biomass while exhibiting no difference in fecundity. These plant species reacted differently to short-term diesel exhaust exposure, suggesting that the impact of diesel exhaust will depend on both the plant species and its physiology.


2021 ◽  
Vol 3 (3) ◽  
pp. 669-680
Author(s):  
Oliver Jonas Jorg ◽  
Mino Sportelli ◽  
Marco Fontanelli ◽  
Christian Frasconi ◽  
Michele Raffaelli ◽  
...  

Vegetable transplanting is an important and advantageous practice in vegetables production systems. In recent years, the development of vegetable transplanting tools has increased, as well as the interest for automatic and robotic transplanters. However, at present, the feeding of transplanting machines is often still performed by hand. This paper presents the design, development and testing of a needle gripper and a two-finger gripper for vegetable transplanting. Both grippers were self-designed and tested for picking, lifting and transplanting plug seedlings. Tests have been conducted on fennel (Foeniculum vulgare L.), leek (Allium ampeloprasum L.) chicory (Cichorium intybus L.) and lettuce (Lactuca sativa L.) seedlings to determine the impact that gripper typology might have on the further growth of plants after transplanting. The average success rate of the two-finger gripper in the transplanting experiment was 95% and of the needle gripper 81.75%, respectively. Although neither gripper typology affected the growth of the seedlings after transplanting, several design implications were identified in order to improve the performance of both grippers. Furthermore, the two-finger gripper is more reliable for lettuce and chicory, while the needle gripper requires root plugs with higher firmness and cohesion to prevent shattering.


2015 ◽  
Vol 66 (10) ◽  
pp. 1071 ◽  
Author(s):  
Julia M. Lee ◽  
Elena M. K. Minnee ◽  
Cameron E. F. Clark

Chicory (Cichorium intybus L.) and narrow-leaved plantain (Plantago lanceolata L.) are capable of producing a large amount of high quality feed during summer. Like many species, grazing management decisions influence their dry matter (DM) production. One of the factors implicated in the grazing-management effect on yield of other forages are plant non-structural carbohydrate (NSC) or nitrogen (N) reserves. The aim of this experiment was to characterise the patterns of NSC and N reserve depletion and replenishment for chicory and plantain during a 35-day regrowth cycle in summer, and investigate the impact of residual height on NSC and N reserves. In chicory roots, the NSC concentration tended (P = 0.09) to decline for 7 days post-defoliation before replenishment began and pre-defoliation concentrations were attained by Day 21 of regrowth (310 growing degree-days; GDD). Similarly, the amount of NSC in plantain roots declined for 14 days post-defoliation (P < 0.001), increasing again from Day 21 and with full replenishment to pre-defoliation levels by Day 35 of regrowth (532 GDD). The two residual heights tested (30 and 60 mm) had minimal impact on NSC reserves during regrowth in either chicory or plantain, likely because the majority of NSC reserves are stored in the roots rather than the stubble. In other plant species, a failure to replenish NSC reserves before the next defoliation is one factor associated with reduced DM production. This also appears to be the case with chicory and plantain, with reductions in DM production occurring if swards are defoliated during NSC mobilisation or the early stages of replenishment (i.e. before 21 days of regrowth or 310 GDD in chicory and 35 days of regrowth or 532 GDD in plantain).


1962 ◽  
Vol 14 ◽  
pp. 415-418
Author(s):  
K. P. Stanyukovich ◽  
V. A. Bronshten

The phenomena accompanying the impact of large meteorites on the surface of the Moon or of the Earth can be examined on the basis of the theory of explosive phenomena if we assume that, instead of an exploding meteorite moving inside the rock, we have an explosive charge (equivalent in energy), situated at a certain distance under the surface.


1962 ◽  
Vol 14 ◽  
pp. 169-257 ◽  
Author(s):  
J. Green

The term geo-sciences has been used here to include the disciplines geology, geophysics and geochemistry. However, in order to apply geophysics and geochemistry effectively one must begin with a geological model. Therefore, the science of geology should be used as the basis for lunar exploration. From an astronomical point of view, a lunar terrain heavily impacted with meteors appears the more reasonable; although from a geological standpoint, volcanism seems the more probable mechanism. A surface liberally marked with volcanic features has been advocated by such geologists as Bülow, Dana, Suess, von Wolff, Shaler, Spurr, and Kuno. In this paper, both the impact and volcanic hypotheses are considered in the application of the geo-sciences to manned lunar exploration. However, more emphasis is placed on the volcanic, or more correctly the defluidization, hypothesis to account for lunar surface features.


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