Treatment of vaginal mucosa in post-menopausal women before and after vaginal surgery

Maturitas ◽  
1984 ◽  
Vol 6 (2) ◽  
pp. 152
Keyword(s):  
Vaginal Surgery ◽  
Vaginal Mucosa ◽  
Menopausal Women ◽  
Before And After ◽  
Post Menopausal

Chai-Hu-Gui-Zhi-Gan-Jiang-Tang Regulates Plasma Interleukin-6 and Soluble Interleukin-6 Receptor Concentrations and Improves Depressed Mood in Climacteric Women with Insomnia

2005 ◽  
Vol 33 (05) ◽  
pp. 703-711 ◽  
Author(s):  
Takahisa Ushiroyama ◽  
Atsushi Ikeda ◽  
Kou Sakuma ◽  
Minoru Ueki
Keyword(s):  
Herbal Medicine ◽  
Depressed Mood ◽  
Interleukin 6 ◽  
Depression Score ◽  
Stress Reactions ◽  
Menopausal Women ◽  
Before And After ◽  
Interleukin 6 Receptor ◽  
Dsm Iv ◽  
Post Menopausal

This study was performed to compare the effects of Chai-hu-gui-zhi-gan-jiang-tang (Saiko-keishi-kankyo-to), an herbal medicine, in improving depressed mood and on plasma interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R) concentrations with those of anti-depressants in peri- and post-menopausal women. Ninety patients complaining of menopausal symptoms including insomnia who were diagnosed with mood disorder based on DSM-IV were recruited and separated into two groups (Chai-hu-gui-zhi-gan-jiang-tang group was selected on the basis of SHO for 42 cases, while anti-depressants were used for 48 cases), and plasma IL-6 and sIL-6R concentrations were determined before and after three months of the treatment. There were no significant differences in the decrease in both climacteric and Hamilton depression score after treatment between the two groups. Plasma IL-6 and sIL-6R concentrations were significantly lower in the Chai-hu-gui-zhi-gan-jiang-tang group (-34.8 ± 15.5% and -22.4 ± 14.6%, respectively) than in the anti-depressant group (7.5 ± 4.8% and 2.4 ± 3.8%, respectively) after 3 months of treatment. Correlations between rate of decrease in climacteric score and plasma IL-6 ( R = 0.498, P = 0.0056) and sIL-6R ( R = 0.512, P = 0.0045) concentrations were observed. Chai-hu-gui-zhi-gan-jiang-tang reduced plasma IL-6 and sIL-6R concentrations in relation to improvement of depressed mood during treatment. The findings of this study suggest that Chai-hu-gui-zhi-gan-jiang-tang has the potential to decrease morbidity by alleviation of stress reactions in peri- and post-menopausal women.

Free Living Energy Expenditure in Post Menopausal Women before and after Exercise Training

2001 ◽  
Vol 11 (2) ◽  
pp. 226-237 ◽  
Author(s):  
Lara R. Keytel ◽  
Michael I. Lambert ◽  
Judith Johnson ◽  
Timothy D. Noakes ◽  
Estelle V. Lambert
Keyword(s):  
Heart Rate ◽  
Body Composition ◽  
Energy Expenditure ◽  
Exercise Training ◽  
Moderate Exercise ◽  
Free Living ◽  
Menopausal Women ◽  
Before And After ◽  
Post Menopausal ◽  
Submaximal Heart Rate

The aim of the study was to determine the effects of 8 weeks of moderate exercise training, on 24-hour free living energy expenditure in previously sedentary post-menopausal women. The experimental group (EX) included 9 women. Ten non-exercising control subjects (CON) were recruited to undergo pre- and post-testing. Estimated total daily energy expenditure (TDEE), total 24-hour heart beats (HB), total energy intake (TEI), resting metabolic rate, maximal oxygen consumption (V̇O2max), body composition, and submaximal heart rate were measured before and after the exercise intervention. Body composition did not change (body fat % in CON 34.0 ± 4.0% vs. 33.9 ± 3.6% and EX 34.1 ± 4.0% vs. 34.0 ± 3.4%). Mean submaximal heart rate during steady-state exercise in EX was lower after training compared to CON (p < .05); however, V̇O2max did not significantly (CON 1.96 ± 0.23 vs. 1.99 ± 0.241 LO2/min and EX 1.86 ± 0.39 vs. 1.94 ± 0.30 LO2/min). Neither estimated TDEE (CON, 11.6 ± 2.0 vs. 11.4 ± 2.78 MJ; and EX 11.4 ± 3.3 vs. 11.5 ± 2.5 MJ, pre vs. post, respectively), RMR (CON 134.2 ± 9.4 vs. 136.9 ± 15.0 KJ/kgFFM/day, and EX 138.4 ± 6.4 vs. 140.7 ± 14.2 KJ/kgFFM/day, pre vs. post, respectively), TEI (CON 7.9 ± 2.2 vs. 8.2 ± 2.5 MJ, and EX 9.4 ±1.6 vs. 8.3 ± 2.8 MJ), nor HB (CON 110,808 ± 12,574 vs. 107,366 ± 12,864 beats, and EX 110,188 ± 9,219 vs. 114,590 ± 12,750 beats) change over 8 weeks in either group. These data suggest that a moderate exercise program may not impact on TDEE, RMR, TEI, or HB in previously sedentary, older women.

Sonographic Abnormalities of Thyroid Gland in pre and post-menopausal women

2021 ◽  
Vol 15 (8) ◽  
pp. 1781-1784
Author(s):  
Namra Adnan ◽  
Syeda Khadija Tul Sughra Murrium ◽  
S. Mohammad Yousaf Farooq ◽  
Syed Amir Gilani
Keyword(s):  
Thyroid Gland ◽  
Postmenopausal Women ◽  
Scientific Literature ◽  
Thyroid Stimulating Hormone ◽  
Mesh Terms ◽  
Key Words Thyroid Gland ◽  
Menopausal Women ◽  
Study Results ◽  
Before And After ◽  
Post Menopausal

Background: Women that are over 50 years are usually diagnosed by thyroid disorders. The prevalence of Thyroiditis, thyroid cancer, found more under postmenopausal women than premenopausal. In the postmenopausal phase the prevalence of biochemical (or subclinical) hypothyroidism rising from 10% to 20%, or increases steadily with age in women. The study results show an enlargement in the activities of Thyroid stimulating hormone among menopausal women. Aim: To compare the sonographic findings of thyroid gland in before and after-menopausal women. Method: An Analysis of scientific literature concerning the correlation of Sonographic abnormalities of thyroid gland in pre and post-menopausal women was done. Different platforms including medical journals, books and online resources (e.g., PubMed, Google Scholar & Medline) were explored to find the relevant data using the mesh Terms: Thyroid gland, premenopausal and postmenopausal women, etc. The main focus was given to the latest data published in the last 10 years. Key words: Thyroid gland, premenopausal and postmenopausal women.

Effects of 28 days of dairy or soy ingestion on skeletal markers of inflammation and proteolysis in post-menopausal women

2012 ◽  
Vol 21 (2) ◽  
pp. 117-130 ◽  
Author(s):  
Monica C Serra ◽  
Kristen M Beavers ◽  
Daniel P Beavers ◽  
Darryn S Willoughby
Keyword(s):  
Skeletal Muscle ◽  
Controlled Trial ◽  
Post Exercise ◽  
Markers Of Inflammation ◽  
Menopausal Women ◽  
Before And After ◽  
Calpain 2 ◽  
Exercise Induced ◽  
Post Menopausal ◽  
Dairy Milk

Background: Aging is associated with increased local inflammation and resultant proteolysis in skeletal muscle. In animal models, soy supplementation is a beneficial countermeasure against muscle inflammation and proteolysis; however, the effect on aging humans is not clear. Methods: A single-blinded, randomized, controlled trial was conducted on 31 post-menopausal women. Volunteers were randomly assigned to consume three servings of soy ( n=16) or dairy ( n=15) milk each day for 28 days. The expression of inflammation-responsive (TNF-α, IL-1β, IL-6) and proteolytic (calpain 1, calpain 2, ubiquitin, E2, atrogin-1, muRF-1) genes in skeletal muscle was determined using real-time polymerase chain reaction before and after supplementation, and then after a downhill run performed to elicit muscle damage. Results: While no group by time interactions were observed, significant main effects for time were observed for IL-1β, IL-6, calpain 2, and atrogin-1 mRNA post exercise. Further analysis revealed that, compared with post-supplementation values, calpain 2 and atrogin-1 mRNA significantly increased at 4 h post exercise ( p=0.01 and p<0.01, respectively), whereas IL-1β and IL-6 mRNA significantly decreased at 4 h post exercise (both p<0.01). Conclusions: Soy or dairy milk supplementation at the amount ingested for 28 days does not appear to preferentially inhibit the expression of inflammation-responsive and proteolytic genes that were assessed, and does not attenuate the eccentric exercise-induced up-regulation in the proteolytic genes.

Elevated Levels of sE-selectin in Post-menopausal Females Are Decreased by Hormone Replacement Therapy to Levels Observed in Pre-menopausal Females

1999 ◽  
Vol 82 (11) ◽  
pp. 1433-1436 ◽  
Author(s):  
Margaret McLaren ◽  
Jill Belch ◽  
Mary Seed ◽  
Gwen Kennedy
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Hormone Replacement ◽  
Endothelial Activation ◽  
Control Group ◽  
Menopausal Women ◽  
Before And After ◽  
Post Menopausal

SummaryObservational epidemological studies have shown that mortality from coronary heart disease is reduced in post-menopausal women by hormone replacement therapy (HRT). The aim of this study was to measure sE-selectin levels in post-menopausal females before and after HRT and to compare these with pre-menopausal females and aged matched males. Post-menopausal females (n = 70) were given HRT or no treatment to act as a control group. sE-selectin levels were significantly lower in the pre-menopausal (n = 36) when compared with the post-menopausal females (n = 70) (p = 0.027), whereas no difference between two age matched male groups was found (n = 40). Oral and transdermal HRT significantly decreased sE-selectin levels (p <0.0001 and p = 0.0005 respectively) with no change in the control group. The reduction in the levels of this marker of endothelial activation after HRT, may reflect a decrease in leucocyte/endothelial interaction which may reduce atherosclerotic risk in post-menopausal females.

Oestrogens, gonadotrophins and SHBG during oral and cutaneous administration of oestradiol-17β to menopausal women

1982 ◽  
Vol 101 (4) ◽  
pp. 592-596 ◽  
Author(s):  
Lars Fåhraeus ◽  
Ulf Larsson-Cohn
Keyword(s):  
Plasma Concentrations ◽  
Sex Hormone Binding Globulin ◽  
Clinical Effects ◽  
Routes Of Administration ◽  
Menopausal Women ◽  
Before And After ◽  
The Mean ◽  
Post Menopausal ◽  
Cutaneous Administration ◽  
The Given

Abstract. Thirty-eight post-menopausal women were randomly allocated to 6 months of treatment with either 2–4 mg of micronized oestradiol-17β taken orally or 3 mg of oestradiol-17β applied cutaneously. The plasma concentrations of oestrone, oestradiol, LH, FSH and sex hormone binding globulin (SHBG) were determined twice before and after 2,4 and 6 months of treatment. In both groups the clinical effects were satisfactory. During treatment the mean oestradiol levels showed similar increases in the two groups while the oestrone concentration was markedly raised only among those taking oestradiol orally. The mean LH and FSH concentrations were significantly lowered in both groups. SHBG was increased with both treatments although more marked in the group on oral medication. Doubling of the oral dose from 2 mg to 4 mg gave significant changes of the LH, FSH and oestrone concentrations. Thus, in the given doses, the two routes of administration seemed to have similar effects on post-menopausal symptoms and on the plasma concentrations of gonadotrophins and oestradiol. However the plasma oestrone and SHBG levels became significantly higher during the oral than during the cutaneous treatment.

scholarly journals COMPARISON OF THE EFFECTS OF WALKING AND BENCH-STEP EXERCISE ON OSTEOCALCIN AND CTX-1 IN POST-MENOPAUSAL WOMEN WITH OSTEOPENIA

2017 ◽  
Vol 20 (02) ◽  
pp. 1750012
Author(s):  
Ignatio Rika Haryono ◽  
Angela Tulaar ◽  
Herawati Sudoyo ◽  
Ambrosius Purba ◽  
Murdani Abdullah ◽  
...  
Keyword(s):  
Bone Formation ◽  
Wilcoxon Test ◽  
Enzyme Linked Immunosorbent Assay ◽  
Test Results ◽  
T Score ◽  
Menopausal Women ◽  
Before And After ◽  
Walking Exercise ◽  
The Difference ◽  
Post Menopausal

Purpose: Bench-step exercise produces biomechanical movements beneficial to improve bone remodeling. However, no studies have confirmed the effects of bench-step exercise (BE) on bone formation and resorption. The goal of this study is to compare the effects of bench-step and walking exercise (WE) on changes in osteocalcin and CTX-1 levels. Methods: Fifty-nine sedentary post-menopausal women with osteopenia (T-score between [Formula: see text]1 and [Formula: see text]2.5) were randomly divided into two groups: WE group ([Formula: see text]) and BE group ([Formula: see text]). Subjects performed 12 weeks of exercise. The osteocalcin and CTX-1 levels were analyzed using enzyme-linked immunosorbent assay. Independent [Formula: see text]-test or Wilcoxon test was used to analyze the osteocalcin and CTX-1 levels. The difference in changes in the osteocalcin and CTX-1 between the groups before and after was analyzed using Mann–Whitney test. Results: The results showed a significant increase in the osteocalcin and CTX-1 levels in both groups ([Formula: see text]). The increased levels of osteocalcin between groups were not statistically different ([Formula: see text]). The increase in CTX-1 resulting from BE was lower than that from WE ([Formula: see text]). Conclusion: This study indicates that BE may inhibit resorption stronger than WE.

Bioavailability of oestriol

1982 ◽  
Vol 99 (1) ◽  
pp. 136-140 ◽  
Author(s):  
D. E. Englund ◽  
K. B. Elamsson ◽  
E. D. B. Johansson
Keyword(s):  
Oral Administration ◽  
Diethyl Ether ◽  
Plasma Levels ◽  
Gradual Decrease ◽  
Specific Antiserum ◽  
Receptor Affinity ◽  
Menopausal Women ◽  
Before And After ◽  
Low Levels ◽  
Post Menopausal

Abstract. A rapid radioimmunoassay, using a specific antiserum against oestriol (Oe3) was developed for the analyses of unconjugated oestriol in post-menopausal women before and after oral administration of oestriol. One ml plasma was extracted once with 10 ml diethyl ether and assayed without further purification. The plasma levels of oestriol in post-menopausal women appear to be below 5 pg/ml. When 10 ml plasma from a pool was assayed 2.9 pg/ml was found. When 1 ml was assayed from individual patients levels between 10–20 pg was found, which was not different from the plasma blank. A rise in plasma oestriol was found already 15 min after oral administration of 6 mg or 12 mg oestriol (Ovesterin®). On the average there was a plasma oestriol peak after 45 min and then a gradual decrease to low levels within 3 to 4 h. It is concluded that oestriol is rapidly absorbed when administered orally. However, the duration of the plasma oestriol elevation is short. Oestriol is rapidly metabolized. The short elevation probably explains the weak oestrogenic effect exerted by oestriol when administered once a day as receptor affinity for oestriol is low.

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