Antibiotic resistance and enhanced insecticide catabolism as consequences of steroid induction in the Gram-negative bacterium Comamonas testosteroni

1996 ◽  
Vol 58 (2) ◽  
pp. 217-223 ◽  
Author(s):  
Udo C.T. Oppermann ◽  
Ivan Belai ◽  
Edmund Maser
Keyword(s):  
Antibiotic Resistance ◽  
Comamonas Testosteroni ◽  
Negative Bacterium ◽  
Gram Negative

scholarly journals Draft Genome Sequence of the Industrially Significant Bacterium Pseudomonas fluorescens ATCC 13525

2018 ◽  
Vol 7 (17) ◽  
Author(s):  
M. J. Meier ◽  
R. M. Subasinghe ◽  
L. A. Beaudette
Keyword(s):  
Antibiotic Resistance ◽  
Pseudomonas Fluorescens ◽  
Virulence Factors ◽  
Draft Genome ◽  
Antibiotic Resistance Genes ◽  
Strain Atcc ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Content Type ◽  
Metabolic Functions

Pseudomonas fluorescens is a Gram-negative bacterium with versatile metabolic functions and potential industrial uses. We sequenced P. fluorescens strain ATCC 13525 with the goal of determining virulence factors and antibiotic resistance genes to predict the potential impacts on human and environmental health in the event of exposure.

scholarly journals Complete Genome Sequence of Escherichia coli Myophage Minorna

2019 ◽  
Vol 8 (23) ◽  
Author(s):  
Katherine Rogers ◽  
Lorna Min ◽  
Heather Newkirk ◽  
Mei Liu ◽  
Jolene Ramsey
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Resistance ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Negative Bacterium ◽  
Treatment Alternative ◽  
Gram Negative ◽  
Content Type ◽  
Viable Treatment

The Gram-negative bacterium Escherichia coli causes many diseases, and antibiotic resistance has become a problem for their treatment. Bacteriophages may present a viable treatment alternative.

scholarly journals Complete Genome Sequence of Multidrug-ResistantPlesiomonas shigelloidesStrain MS-17-188

2018 ◽  
Vol 6 (18) ◽  
Author(s):  
Hossam Abdelhamed ◽  
Ozan Ozdemir ◽  
Hasan C. Tekedar ◽  
Mark A. Arick ◽  
Chuan-Yu Hsu ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Molecular Mechanisms ◽  
Multidrug Resistant ◽  
Negative Bacterium ◽  
Gram Negative ◽  
Plesiomonas Shigelloides ◽  
Content Type

ABSTRACTPlesiomonas shigelloidesis a Gram-negative bacterium isolated from diverse environments. Here, we describe the complete genome sequence of the multidrug-resistantP. shigelloidesstrain MS-17-188, isolated from a diseased catfish. Availability of this genome will be beneficial for characterizing the molecular mechanisms of antibiotic resistance in this strain.

scholarly journals Complete Genome Sequence of Klebsiella pneumoniae Siphophage Sugarland

2018 ◽  
Vol 7 (19) ◽  
Author(s):  
Samuel G. Erickson ◽  
Lauren Lessor ◽  
Chandler J. O'Leary ◽  
Jason J. Gill ◽  
Mei Liu
Keyword(s):  
Antibiotic Resistance ◽  
Gastrointestinal Tract ◽  
Klebsiella Pneumoniae ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Phage Therapy ◽  
Negative Bacterium ◽  
Nosocomial Pathogen ◽  
Gram Negative ◽  
Content Type

Klebsiella pneumoniae is a Gram-negative bacterium associated with the gastrointestinal tract and is a significant nosocomial pathogen due to its antibiotic resistance. Phage therapy against K. pneumoniae may prove useful in treating infections caused by this bacterium.

Extended Spectrum Beta Lactamase (ESBL), bla TEM,bla SHVand bla CTX-M,resistance genes in Community and Healthcare Associated Gram Negative Bacteria from Osun State, Nigeria

2020 ◽  
Vol 20 ◽  
Author(s):  
Ganiyat Shitta ◽  
Olufunmilola Makanjuola ◽  
Olusolabomi Adefioye ◽  
Olugbenga Adekunle Olowe
Keyword(s):  
Antibiotic Resistance ◽  
Resistance Genes ◽  
Gram Negative Bacteria ◽  
Beta Lactamase ◽  
Multiple Antibiotic Resistance ◽  
Esbl Production ◽  
Gram Negative ◽  
Extended Spectrum Beta Lactamase ◽  
Healthcare Associated ◽  
Esbl Producers

Background: Extended Spectrum Beta Lactamase (ESBL) production in gram negative bacteria confers multiple antibiotic resistance, adversely affecting antimicrobial therapy in infected individuals. ESBLs result from mutations in β-lactamases encoded mainly by the bla TEM,bla SHVand bla CTX-Mgenes. The prevalence of ESBL producing bacteria has been on the increase globally especially its upsurge among isolates from community-acquired infections. Aim: To determine ESBL prevalence and identify ESBL genes among clinical isolates in Osun State, Nigeria. Material and Methods: A cross-sectional study was carried out from August 2016 –July 2017 in Osun State, Nigeria. Three hundred and sixty Gram negative bacteria recovered from clinical samples obtained from both community and healthcare associated infections were tested. They included147 Escherichia coli(40.8%), 116 Klebsiella spp(32.2%), 44 Pseudomo-nas aeruginosa(12.2%) and23 Proteus vulgaris (6.4%) isolates. Others were Acinetobacter baumannii, Serratia rubidae, Citrobacter spp, Enterobacter spp and Salmonella typhi. Disk diffusion antibiotic susceptibility testing was carried out, isolates were screened for ESBL production and confirmed using standard laboratory procedures. ESBLs resistance genes were identified by Polymerase Chain Reaction (PCR). Results: All isolates demonstrated multiple antibiotic resistance. Resistance to ampicillin, amoxicillin with clavulanate and erythromycin was 100%, whereas resistance to Imipenem was very low (5.0%). : Overall prevalence of ESBL producers was 41.4% with Klebsiellaspp as the highest ESBL producing Enterobacteriacaea. ESBL producers were more prevalent among the hospital pathogens than community pathogens, 58% vs 29.5% (p=0.003). ESBL genes were detected in all ESBL producers with the blaCTX-Mgene predominating (47.0%) followed by blaTEM(30.9%) and blaSHVgene was the least, 22.1%. The blaCTX-Mgene was also the most prevalent in the healthcare pathogens (62%) but it accounted for only 25% in those of community origin. Conclusion: A high prevalence of ESBL producing gram negative organisms occurs both in healthcare and in the community in our environment with the CTX-M variant predominating. Efforts to control spread of these pathogens should be addressed.

scholarly journals Massiliamide, a cyclic tetrapeptide with potent tyrosinase inhibitory properties from the Gram-negative bacterium Massilia albidiflava DSM 17472T

2020 ◽  
Author(s):  
Andri Frediansyah ◽  
Jan Straetener ◽  
Heike Brötz-Oesterhelt ◽  
Harald Gross
Keyword(s):  
Absolute Configuration ◽  
Inhibitory Activity ◽  
Liquid Culture ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Negative Bacterium ◽  
Gram Negative ◽  
The Absolute ◽  
Potent Inhibitory Activity ◽  
Cyclic Tetrapeptide

AbstractA cyclic tetrapeptide, designated massiliamide, was isolated from the liquid culture of the Gram-negative bacterium Massilia albidiflava DSM 17472T. The structure was elucidated through extensive spectroscopic analysis, including HR-MS and 1D and 2D NMR experiments. The absolute configuration was determined using the Marfey´s method. Massiliamide showed potent inhibitory activity towards tyrosinase with an IC50 value of 1.15 µM and no cytotoxicity.

scholarly journals Porphyromonas gingivalis fimbrial protein Mfa5 contains a von Willebrand factor domain and an intramolecular isopeptide

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Thomas V. Heidler ◽  
Karin Ernits ◽  
Agnieszka Ziolkowska ◽  
Rolf Claesson ◽  
Karina Persson
Keyword(s):  
Porphyromonas Gingivalis ◽  
Von Willebrand Factor ◽  
Host Cells ◽  
Negative Bacterium ◽  
Oral Biofilm ◽  
Gram Negative ◽  
Type V ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Fimbrial Protein

AbstractThe Gram-negative bacterium Porphyromonas gingivalis is a secondary colonizer of the oral biofilm and is involved in the onset and progression of periodontitis. Its fimbriae, of type-V, are important for attachment to other microorganisms in the biofilm and for adhesion to host cells. The fimbriae are assembled from five proteins encoded by the mfa1 operon, of which Mfa5 is one of the ancillary tip proteins. Here we report the X-ray structure of the N-terminal half of Mfa5, which reveals a von Willebrand factor domain and two IgG-like domains. One of the IgG-like domains is stabilized by an intramolecular isopeptide bond, which is the first such bond observed in a Gram-negative bacterium. These features make Mfa5 structurally more related to streptococcal adhesins than to the other P. gingivalis Mfa proteins. The structure reported here indicates that horizontal gene transfer has occurred among the bacteria within the oral biofilm.

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