Mechanical properties and bioactive surface modification via alkali-heat treatment of a porous Ti–18Nb–4Sn alloy for biomedical applications

Bacterial cellulose is a naturally occurring polysaccharide with numerous biomedical applications that range from drug delivery platforms to tissue engineering strategies. BC possesses remarkable biocompatibility, microstructure, and mechanical properties that resemble native human tissues, making it suitable for the replacement of damaged or injured tissues. In this review, we will discuss the structure and mechanical properties of the BC and summarize the techniques used to characterize these properties. We will also discuss the functionalization of BC to yield nanocomposites and the surface modification of BC by plasma and irradiation-based methods to fabricate materials with improved functionalities such as bactericidal capabilities.

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Development and Characterization of New Ti-25Ta-Zr Alloys for Biomedical Applications

Materials Science Forum ◽

10.4028/www.scientific.net/msf.1016.137 ◽

2021 ◽

Vol 1016 ◽

pp. 137-144

Author(s):

Pedro Akira Bazaglia Kuroda ◽

Fernanda de Freitas Quadros ◽

Mycaela Vieira Nascimento ◽

Carlos Roberto Grandini

Keyword(s):

Mechanical Properties ◽

Heat Treatment ◽

Elastic Modulus ◽

Biomedical Applications ◽

Solution Heat Treatment ◽

High Hardness ◽

Microstructural Characterization ◽

Β Phase ◽

Cp Ti ◽

Microscopy Techniques

This paper deals with the study of the development, structural and microstructural characterization and, selected mechanical properties of Ti-25Ta-50Zr alloy for biomedical applications. The alloy was melted in an arc furnace and various solution heat treatments were performed to analyze the influence of the temperature and time on the structure, microstructure, microhardness and elastic modulus of the samples. The structural and microstructural results, obtained by X-ray diffraction and microscopy techniques, showed that the solution heat treatment performed at high temperatures induces the formation of the β phase, while solution heat treatment performed at low temperatures induces the formation of the α” and ω metastable phases. Regarding the effect of time, samples subjected to heat treatment for 6 hours have only the β phase, indicating that lengthy treatments suppress the α” phase. Regarding the hardness and elastic modulus, the alloy with the α” and ω phases, after treatment performed at a temperature of 500 °C, has a high hardness value and elastic modulus due to the presence of the ω phase that hardens and weakens alloys. The titanium alloys developed in this study have excellent mechanical properties results for use in the orthopedic area, better than many commercial materials such as cp-Ti, stainless steel and Co-Cr alloys.

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Heat Treatment Effect on Mechanical Properties of 3D Printed Polymers

MATEC Web of Conferences ◽

10.1051/matecconf/201926402001 ◽

2019 ◽

Vol 264 ◽

pp. 02001 ◽

Cited By ~ 1

Author(s):

Eduardo de Avila ◽

Jaeseok Eo ◽

Jihye Kim ◽

Namsoo P. Kim

Keyword(s):

Mechanical Properties ◽

Heat Treatment ◽

Treatment Effect ◽

Biomedical Applications ◽

Treatment Process ◽

Heat Treatment Process ◽

Post Heat Treatment ◽

Intraocular Surgery ◽

Osteoinductive Potential ◽

3D Printed

PMMA, PC, and PEEK are thermoplastic polymers that possess favorable properties for biomedical applications. These polymers have been used in fields of maxillo-facial, orthopedic, intraocular surgery, and bio-implant, due to their excellent mechanical properties, osteoinductive potential, and antimicrobial capabilities. In this study, the effect of heat treatment on the mechanical properties of 3D printed polymers was characterized. By modifying printing temperature and post heat treatment process, the mechanical properties were specifically tailored for different applications, correlating with the properties of the implants that are commonly made using molding processes.

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Electrophoretic Deposition of Carbon Nanotubes over TiO2Nanotubes: Evaluation of Surface Properties and Biocompatibility

Bioinorganic Chemistry and Applications ◽

10.1155/2014/236521 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 7

Author(s):

Jung Eun Park ◽

Il Song Park ◽

Tae Sung Bae ◽

Min Ho Lee

Keyword(s):

Mechanical Properties ◽

Carbon Nanotubes ◽

Corrosion Resistance ◽

Surface Modification ◽

Electrophoretic Deposition ◽

Biomedical Applications ◽

Controlled Drug Delivery ◽

Chemical Durability ◽

Surface Modified ◽

Excellent Chemical

Titanium (Ti) is often used as an orthopedic and dental implant material due to its better mechanical properties, corrosion resistance, and excellent biocompatibility. Formation of TiO2nanotubes (TiO2NTs) on titanium is an interesting surface modification to achieve controlled drug delivery and to promote cell growth. Carbon nanotubes (CNTs) possess excellent chemical durability and mechanical strength. The use of CNTs in biomedical applications such as scaffolds has received considerable attention in recent years. The present study aims to modify the surface of titanium by anodizing to form TiO2NTs and subsequently deposit CNTs over it by electrophoretic deposition (EPD). Characteristic, biocompatibility, and apatite forming ability of the surface modified samples were evaluated. The results of the study reveal that CNTs coating on TiO2nanotubes help improve the biological activity and this type of surface modification is highly suitable for biomedical applications.

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Surface Modification of Biomedical Titanium Alloy: Micromorphology, Microstructure Evolution and Biomedical Applications

Coatings ◽

10.3390/coatings9040249 ◽

2019 ◽

Vol 9 (4) ◽

pp. 249 ◽

Cited By ~ 25

Author(s):

Wei Liu ◽

Shifeng Liu ◽

Liqiang Wang

Keyword(s):

Mechanical Properties ◽

Titanium Alloy ◽

Surface Modification ◽

Microstructure Evolution ◽

Biomedical Applications ◽

Cellular Level ◽

Implant Surface ◽

Potential Applications ◽

Biomedical Titanium Alloy ◽

Increasing Demand

With the increasing demand for bone implant therapy, titanium alloy has been widely used in the biomedical field. However, various potential applications of titanium alloy implants are easily hampered by their biological inertia. In fact, the interaction of the implant with tissue is critical to the success of the implant. Thus, the implant surface is modified before implantation frequently, which can not only improve the mechanical properties of the implant, but also polish up bioactivity and osseoconductivity on a cellular level. This paper aims at reviewing titanium surface modification techniques for biomedical applications. Additionally, several other significant aspects are described in detail in this article, for example, micromorphology, microstructure evolution that determines mechanical properties, as well as a number of issues concerning about practical application of biomedical implants.

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