Photocatalytic effects of titanium dioxide nanoparticles on aquatic organisms—Current knowledge and suggestions for future research

Titanium dioxide nanoparticles (nano-TiO2), one of the most produced engineered nanoparticles (ENPs), are used in pigments, photocatalysis, food additives, and personal care products.

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Study on titanium dioxide nanoparticles as MALDI MS matrix for the determination of lipids in the brain

Green Processing and Synthesis ◽

10.1515/gps-2021-0056 ◽

2021 ◽

Vol 10 (1) ◽

pp. 700-710

Author(s):

Congnan Peng ◽

Qian Zhang ◽

Jian-an Liu ◽

Zhen-peng Wang ◽

Zhen-wen Zhao ◽

...

Keyword(s):

Mass Spectrometry ◽

Titanium Dioxide ◽

Titanium Dioxide Nanoparticles ◽

Brain Homogenate ◽

Maldi Ms ◽

Absolute Ethanol ◽

Future Research ◽

Ionization Mass ◽

The Matrix

Abstract The structures of lipids are diverse, and thus, lipids show various biological functions. Systematic determination of lipids in organisms has always been a concern. In this paper, a methodology on the matrix-assisted laser desorption ionization mass spectrometry (MALDI MS), with titanium dioxide nanoparticles (TiO2 NPs) as the matrix, was studied for lipid determination. The results showed that the following conditions were preferable in the determination of small-molecule lipids (such as hypoxanthine, guanosine, uridine, and cytidine), lipid standards (such as GC, GM, TG, phosphatidylethanolamine, phosphatidylcholine, and ceramide), and mixed lipids (extracted from brain homogenate with methanol alone and with the B&D method): TiO2 NPs as the matrix, absolute ethanol as the solvent, 1 mg of TiO2 NPs dispersed in 1 mL of absolute ethanol as the matrix solution, NaCl as the ionization reagent, and positive mass spectrometry (MS) as the mode. Modified TiO2 NP as a new matrix for MALDI MS will be a future research direction; in addition, the characteristics of TiO2 NPs make it a potential matrix for imaging MS.

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Effects of Glyphosate and Their Metabolite AMPA on Aquatic Organisms

10.20944/preprints202109.0028.v1 ◽

2021 ◽

Author(s):

Nikola Tresnakova ◽

Alzbeta Stara ◽

Josef Velisek

Keyword(s):

Current Knowledge ◽

Aquatic Organisms ◽

Aquatic Organism ◽

Major Metabolite ◽

Future Research ◽

Oxidative Stress Biomarkers ◽

Research Knowledge ◽

Stress Biomarkers ◽

Aminomethylphosphonic Acid ◽

Herbicide Glyphosate

Glyphosate (N-(phosphonomethyl)glycine) is a herbicide used to kill broadleaf weeds and grass, developed in the early 1970s. The widely occurring degradation product aminomethylphosphonic acid (AMPA) is a result of glyphosate and amino-polyphosphonate degradation. The massive use of the parent compounds leads to the ubiquity of AMPA in the environment, and particularly in water. Considering this, it can be assumed that glyphosate and its major metabolites could pose a potential risk to aquatic organisms. This review summarises current knowledge about residual glyphosate and their major metabolite AMPA in the aquatic environment, including status and toxic effects in aquatic organisms, mainly fish, are reviewed. Based on the above, we identify major gaps in the current knowledge and some directions for future research knowledge about the effects of worldwide use of herbicide glyphosate and its major metabolite AMPA. The toxic effect of glyphosate and their major metabolite AMPA has mainly influenced growth, early development, oxidative stress biomarkers, antioxidant enzymes, haematological, biochemical plasma indices, caused histopathological changes in the aquatic organism.

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Residual pharmaceutically active compounds (PhACs) in aquatic environment – status, toxicity and kinetics: a review

Veterinární Medicína ◽

10.17221/97/2009-vetmed ◽

2009 ◽

Vol 54 (No. 7) ◽

pp. 295-314 ◽

Cited By ~ 42

Author(s):

Z.H. Li ◽

T. Randak

Keyword(s):

Aquatic Environment ◽

Current Knowledge ◽

Influence Factors ◽

Aquatic Organisms ◽

Future Research ◽

Pharmacokinetic Parameters ◽

Pharmaceutically Active Compounds ◽

Active Compounds ◽

Environmental Evaluation ◽

Detection Techniques

Awareness of residual pharmaceutically active compounds (PhACs) in aquatic ecosystems is growing as research into these pollutants increases and analytical detection techniques improve. For most pharmaceuticals analyzed, the effects on aquatic organisms have usually been investigated by toxic assays in the laboratory. However, little is known about integral analysis of pharmacokinetics in aquatic organisms and specific relations between pharmacokinetic parameters and influence factors. Moreover, the influence of the organisms involved and numerous other external factors complicates development of standard tests for environmental evaluation. Current knowledge about residual pharmaceuticals in the aquatic environment, including status, toxic effects, and pharmacokinetics in aquatic organisms, are reviewed. Based on the above, we identify major gaps in the current knowledge and some directions for future research, such as improvement of techniques to remove residual pharmaceuticals from wastewater, and the establishment of standard pharmaceutical modes of action.

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Effects of Glyphosate and Its Metabolite AMPA on Aquatic Organisms

Applied Sciences ◽

10.3390/app11199004 ◽

2021 ◽

Vol 11 (19) ◽

pp. 9004

Author(s):

Nikola Tresnakova ◽

Alzbeta Stara ◽

Josef Velisek

Keyword(s):

Current Knowledge ◽

Parent Compound ◽

Aquatic Organisms ◽

Major Metabolite ◽

Future Research ◽

Oxidative Stress Biomarkers ◽

Research Knowledge ◽

Stress Biomarkers ◽

Aminomethylphosphonic Acid ◽

Herbicide Glyphosate

Glyphosate (N-(phosphonomethyl)glycine) was developed in the early 1970s and at present is used as a herbicide to kill broadleaf weeds and grass. The widely occurring degradation product aminomethylphosphonic acid (AMPA) is a result of glyphosate and amino-polyphosphonate degradation. The massive use of the parent compound leads to the ubiquity of AMPA in the environment, and particularly in water. Considering this, it can be assumed that glyphosate and its major metabolites could pose a potential risk to aquatic organisms. This review summarizes current knowledge about residual glyphosate and its major metabolite AMPA in the aquatic environment, including its status and toxic effects in aquatic organisms, mainly fish. Based on the above, we identify major gaps in the current knowledge and some directions for future research knowledge about the effects of worldwide use of herbicide glyphosate and its major metabolite AMPA. The toxic effect of glyphosate and its major metabolite AMPA has mainly influenced growth, early development, oxidative stress biomarkers, antioxidant enzymes, haematological, and biochemical plasma indices and also caused histopathological changes in aquatic organisms.

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Hazardous Effects of Titanium Dioxide Nanoparticles in Ecosystem

Bioinorganic Chemistry and Applications ◽

10.1155/2017/4101735 ◽

2017 ◽

Vol 2017 ◽

pp. 1-12 ◽

Cited By ~ 44

Author(s):

Syed Niaz Ali Shah ◽

Zahir Shah ◽

Muzammal Hussain ◽

Muzaffar Khan

Keyword(s):

Titanium Dioxide ◽

Biomedical Research ◽

Molecular Level ◽

Titanium Dioxide Nanoparticles ◽

Future Research ◽

Future Prospects ◽

The Past ◽

Toxicological Profile

Although nanoparticles (NPs) have made incredible progress in the field of nanotechnology and biomedical research and their applications are demanded throughout industrial world particularly over the past decades, little is known about the fate of nanoparticles in ecosystem. Concerning the biosafety of nanotechnology, nanotoxicity is going to be the second most priority of nanotechnology that needs to be properly addressed. This review covers the chemical as well as the biological concerns about nanoparticles particularly titanium dioxide (TiO2) NPs and emphasizes the toxicological profile of TiO2at the molecular level in both in vitro and in vivo systems. In addition, the challenges and future prospects of nanotoxicology are discussed that may provide better understanding and new insights into ongoing and future research in this field.

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