Medication adherence in schizophrenia

2016 ◽  
Vol 33 (S1) ◽  
pp. S586-S586
Author(s):  
F. Fatma ◽  
I. Baati ◽  
S. Omri ◽  
R. Sallemi ◽  
J. Masmoudi
Keyword(s):  
Substance Use ◽  
Medication Adherence ◽  
Rating Scale ◽  
Paranoid Schizophrenia ◽  
Poor Adherence ◽  
University Hospital ◽  
Cross Sectional ◽  
Stigma Scale ◽  
Need For Treatment ◽  
Schizophrenic Patients

IntroductionCompliance is a major issue in the treatment of schizophrenia. Many studies have attempted to identify factors that influence it.ObjectiveTo assess treatment adherence in patients with schizophrenia. To identify factors correlated with poor adherence.MethodsIt was a cross-sectional, descriptive and analytical study, involving 37 outpatients with DSM-IV diagnosis of schizophrenia, followed in the psychiatry department at the Hédi Chaker University Hospital of Sfax (Tunisia). The questionnaire included socio-demographic, clinical and therapeutic data. We also used the Medication Adherence Rating Scale “MARS”, the Insight Scale “IS” and the Stigma Scale (9 items).ResultsThe average age was 36.4 years. The majority of patients was male (68.8%), did not exceed the level of secondary education (89.2%) and had a low socioeconomic level (84.4%).Paranoid schizophrenia was the most frequent type of schizophrenia (54.1%). Atypical antipsychotic were prescribed in 40.5% of cases.Patients were non-adherent to treatment in 56.8% of cases. The factors correlated with poor adherence were: psychoactive substance use (P = 0.036), sexual dysfunction (P = 0.036), complexity of treatment (P = 0.036), poor insight according to the subscale “awareness of the need for treatment” of the IS (P = 0.047) and high score on the subscale “discrimination” of the Stigma Scale (P = 0.008).ConclusionTunisian schizophrenic patients have a poor adherence to treatment. Acting on risk factors (such as substance use, sexual side effects, poor insight and discrimination perception) would improve patient compliance and management of schizophrenia.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Medication compliance in schizophrenic out patients with psychoactive substance use co-morbidity: a cross-sectional study

2021 ◽  
Vol 10 (1) ◽  
pp. 167
Author(s):  
Saurabh Ahlawat ◽  
Vikrant Aggarwal ◽  
Rakesh Kumar
Keyword(s):  
Substance Use ◽  
Medication Adherence ◽  
Rating Scale ◽  
Medication Compliance ◽  
Cross Sectional Study ◽  
High Rate ◽  
Psychoactive Substance ◽  
Cross Sectional ◽  
Co Morbidity ◽  
Schizophrenic Patients

Background: Medication adherence is an important issue in the treatment and management of persons with psychiatric disorders including schizophrenia. Apart from side effects and inefficient outcomes of psychiatric medications, substance abuse also complicates the adherence pattern to the prescribed medications. Present study was designed to estimate the magnitude of medication non-adherence and its correlates in patients with schizophrenia having co-morbid psychoactive substance use.Method: The 60 schizophrenic patients with active substance use were taken from OPD of institute of mental health and hospital, Agra. Positive and negative syndrome scale (PANSS), alcohol, smoking and substance involvement screening test (ASSIST), medication adherence rating scale (MARS) and Morisky 8-item medication adherence questionnaire (MMAQ-8) were used to gather relevant clinical data along with a proforma for recording socio-demographic characteristics.Results: The results revealed an alarming level of medication adherence. The 91.7% sample (55 patients) met the criteria for medication non-adherence. Majority of the patients were using alcohol (58.3%) and cannabis (51.7%). Conclusions: Given the high rate of medication non-compliance it is suggested that specific intervention aimed at compliance to prescribed medication is needed in this population.

scholarly journals Medication Adherence among Mentally Ill Patients with comorbid- Substance Use Disorder

KYAMC Journal ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 602-609
Author(s):  
Nasim Jahan ◽  
Mohammad Muntasir Maruf ◽  
Md Faruk Hossain ◽  
Md Waziul Alam Chowdhury ◽  
Anwara Begum
Keyword(s):  
Substance Use ◽  
Medication Adherence ◽  
Mentally Ill ◽  
Substance Misuse ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Psychiatric Medication ◽  
Cross Sectional ◽  
Care Givers

Substance misuse is usually associated with poorer psychiatric medication adherence among mentally ill patients. Identifying proportion & predictors of medication adherence among patients with dual psychiatric and substance misuse problems is important because poor adherence is associated with relapse and re-hospitalization. This study was a descriptive cross sectional study conducted among the patients dually diagnosed with psychiatric and substance use disorders attending OPD in a tertiary care hospital of Dhaka city, during the period from May 2013 to November 2013. The main objective of the study was to explore the proportion of psychotropic medication adherence among the respondents who were on such medication for at least last 6 months (N=151). Respondents were selected purposefully. An informed consent was taken from the patients or care givers and data were collected using the questionnaire designed by the researcher based on Factors Influencing Neuroleptic Medication Taking Scale (FNIMTS). Diagnoses were done previously according to DSM-IV TR by psychiatrist appointed in inpatient and outpatient department. Questionnaire was filled up by the researcher by interviewing the patients and attending care givers as needed. Over half of the respondents (57.0%) admitted they had missed taking their medications on more than one occasion in the week prior to the interview. Thus this study found the proportion of medication adherence to be 43% among the respondents.KYAMC Journal Vol. 6, No.-2, Jan 2016, Page 602-609

scholarly journals A comparison of pain registration by Visual Analog Scale and Numeric Rating Scale – a cross-sectional study of primary triage registration

2020 ◽  
Author(s):  
Jofrid Kollltveit ◽  
Malin Osaland ◽  
Marianne Reimers ◽  
Magnus Berle
Keyword(s):  
Emergency Department ◽  
Visual Analog Scale ◽  
Rating Scale ◽  
Emergency Admission ◽  
Numeric Rating Scale ◽  
University Hospital ◽  
Analog Scale ◽  
Cross Sectional ◽  
Significant Difference ◽  
Numeric Rating

BackgroundPain is a subjective sensation; self-reporting is important for quantifying pain intensity. There are several different validated tools for this, such as Visual Analog Scale and Numeric Rating Scale. In the clinic, these terms are often used as equivalent. The objective of this study was to examine correlation and agreement between the pain registration tools in triage in an emergency department.Materials and MethodsThe study was performed in the Department of Emergency Medicine at Haukeland University Hospital in the period June-August 2019. We registered the pain score with two tools in 200 unselected patients in emergency admission with pain. In addition, we registrered gender, age, triage and general department affiliation.ResultsWe found a strong correlation between the pain registration tools by Spearmans correlation test (rho=0,930, p<0,001). There were no significant difference between the pain registration tools within the subgroups. Bland-Altman analysis show agreement between the two pain registration tools.ConclusionsIn an Emergency Department triage is it acceptable to use Visual Analog Scale and Numeric Rating Scale as equivalent, as long as the correct terminology is used.

scholarly journals Medications adherence level and its associated factors among hypertensive patients at a major referral hospital, in Riyadh, KSA

2016 ◽  
Vol 7 (4) ◽  
pp. 24-30
Author(s):  
Shaffi Ahamed Shaik ◽  
Abeer Alsuwailem ◽  
Afnan Alhargan ◽  
Asma Alswailem ◽  
Dania Alshiha ◽  
...  
Keyword(s):  
Health Status ◽  
Associated Factors ◽  
Poor Adherence ◽  
University Hospital ◽  
Monthly Income ◽  
Self Perception ◽  
Adherence Level ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Perception Of Health

Aims and Objectives: To quantify the level of medications adherence among hypertensive patients and to identify factors of poor adherence.Materials and Methods: A cross sectional study was conducted during October 2013 to March 2014 in King Khalid University Hospital, Riyadh, KSA. Self-administrative questionnaires were used among 310 randomly selected hypertensive patients. Morisky adherence questionnaire was used to quantify adherence level of medications. Adherence scores were categorized as poor and high adherence. Bi-variate and multivariate analysis were used to identity factors associated with poor adherence.Results: Out of 287 patients who had responded, 124(44%) were of less than 50 years of age. Prevalence of poor adherence to medications was 55%. Age, educational status, monthly income, time of diagnosis, self-perception of health status, regular checkup at clinics, & regular blood pressure checkup were significantly associated with ‘level of adherence (poor and high) to medications. The independent associated factors of poor adherence were: age (<50 years): 2.30 (95% confidence interval(CI): 1.29,4.10), monthly income (<5000 Saudi Riyals): 6.58(1.67,25.97), self-perception of health status (uncontrolled): 2.66 (1.20,5.90), and regular checkup at clinics (No): 5.57(2.83,10.97).Conclusion: Level of adherence was low among hypertensive patients. Associated factors of poor adherence could be used to identity patients for counselling in improving level of adherence to medications.Asian Journal of Medical Sciences Vol.7(4) 2016 24-30

scholarly journals Prevalence and Type of Sexual Dysfunction in Female Patients Receiving Antidepressant Medications

2020 ◽  
Vol 2 (2) ◽  
pp. 158-164
Author(s):  
Sandeep Grover ◽  
Natasha Kate ◽  
Eepsita Mishra ◽  
Ajit Avasthi
Keyword(s):  
Medication Adherence ◽  
Sexual Dysfunction ◽  
Rating Scale ◽  
Sexual Experience ◽  
Interpersonal Relationship ◽  
Cutoff Score ◽  
Medical Illness ◽  
Cross Sectional ◽  
Female Patients ◽  
Antidepressant Medications

Aim: To assess the prevalence and typology of sexual dysfunction in female patients receiving antidepressant medications using the Arizona Sexual Experience Scale (ASEX). Method: A cross-sectional design was employed. A total of 71 married women with various psychiatric disorders receiving antidepressants for at least 3 months’ were evaluated on ASEX, Brief Adherence Rating Scale, Medication Adherence Questionnaire, and Global Assessment of Functioning (GAF) scale. Subjects with a history of sexual dysfunction prior to psychotropic intake, menopause, severe interpersonal relationship problems with spouse, or chronic medical illness were excluded. Results: The study sample had the mean age of 37.35 (SD: 6.82) years. More than four-fifth (80.2%) of patients had sexual dysfunction as per the ASEX. Using a cutoff score of 4 or more to define sexual dysfunction in various domains, decreased desire was seen in 81.7%, reduced arousal was seen in 80.3%, poor vaginal lubrication was seen in 76.1%, reduced satisfaction was seen in 57.7%, and reduced ability to reach orgasm was seen in 50.7%. Despite this, few patients (13.3%) discussed their sexual dysfunction with their treating psychiatrist. Sexual dysfunction did not influence the medication adherence. Conclusions: Sexual dysfunction is quite prevalent in female patients receiving antidepressant medications; however, this is not adequately discussed by the patient or the treating psychiatrist.

A Short Scale for Rating Paranoid Schizophrenia

1959 ◽  
Vol 105 (440) ◽  
pp. 815-818 ◽  
Author(s):  
P. H. Venables ◽  
N. O'Connor
Keyword(s):  
Rating Scale ◽  
Paranoid Schizophrenia ◽  
Experimental Studies ◽  
Short Scale ◽  
Chronic Schizophrenics ◽  
Schizophrenic Patients ◽  
Experimental Laboratory ◽  
Paranoid Symptoms

Experimental studies by O'Connor (2) and O'Connor and Rawnsley (3) have indicated the value of separating chronic schizophrenics into those who exhibit and those who do not exhibit paranoid symptoms. Other work by O'Connor and Venables (4) and Venables and O'Connor (6) has shown that performance of schizophrenic patients on experimental laboratory tasks may be clarified by dividing them into active or withdrawn groups by means of a rating scale (Venables, 5) in addition to a division on the basis of the presence of paranoid symptoms.

scholarly journals The influence of depressive symptoms and substance use on adherence to antiretroviral therapy. A cross-sectional prevalence study

2014 ◽  
Vol 133 (3) ◽  
pp. 179-186 ◽  
Author(s):  
Claudia Siqueira Tufano ◽  
Ricardo Abrantes do Amaral ◽  
Luciana Roberta Donola Cardoso ◽  
André Malbergier
Keyword(s):  
Substance Use ◽  
Depressive Symptoms ◽  
Rating Scale ◽  
Stable Condition ◽  
Treatment Interruption ◽  
Prevalence Study ◽  
Treatment Center ◽  
Cross Sectional ◽  
Cd4 Cell Count ◽  
The Past

CONTEXT AND OBJECTIVE:Adherence to antiretroviral treatment (ART) is not a stable condition, but is dynamic, like mental conditions. The aim of this study was to examine whether non-adherence to ART is related to demographic and immunological variables, substance use and presence of depressive symptoms.DESIGN AND SETTING:This was a cross-sectional prevalence study carried out at a public AIDS treatment center in the city of São Paulo, Brazil, between July 2006 and January 2007.METHODS:438 patients on regular ART schedules with recent laboratory tests answered a demographic questionnaire, questions about substance use, the Hamilton Depression Rating Scale (HDRS) and the Simplified Medication Adherence Questionnaire (SMAQ).RESULTS:The prevalence of non-adherence over the past three months (a pattern of treatment interruption) was 46.3%, and 27.2% also reported this in the past week (a pattern of missed doses). ART interruption was significantly related to older age, lower CD4+ cell count and homosexual/bisexual transmission. The pattern of missed doses was significantly related to younger age, higher HDRS scores and higher viral load of RNA HIV.CONCLUSION:ART interruption may reflect recall errors and changes to the Brazilian demographic characteristics of HIV infection. The missed doses may reflect lifestyle characteristics of younger individuals. Attendance for HIV-positive individuals, particularly younger patients, should involve interventions and counseling in relation to the presence of depressive symptoms.

scholarly journals Role of Clinical Pharmacist in Promoting Patient Compliance through Assessment of Reasons for Non-Compliance and Minimum Maintenance Dose Titrations in Schizophrenic Patients

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Mounica. Bollu ◽  
Shaik Faizan Ali ◽  
Dr. Desu Brahma Srinivasa Rao ◽  
Nallani Venkataramarao ◽  
Dr. Nalluri. Murali Krishna M.D
Keyword(s):  
Medication Adherence ◽  
Paranoid Schizophrenia ◽  
Therapeutic Interventions ◽  
Dose Titration ◽  
Improve Medication Adherence ◽  
Access To Treatment ◽  
Schizophrenic Patients ◽  
Area Of Concern ◽  
Group B ◽  
The Individual

Context: Medication non-compliance is an important area of concern in schizophrenia as it contributes to relapse and re-hospitalization of the patients. Constant advancement and study of therapeutic interventions designed to improve medication adherence and the outcome of dose titrations are required to reap the most valuable benefits from the pharmacologic treatment of schizophrenia. Aim & Objective: The aim of the present study is to find out the reasons for drug non-compliance and the effectiveness of treatment outcomes after dose titrations in schizophrenic patients and the main objective is to educate the patient by counseling about the disease, drugs and the importance of medication adherence. Materials and Methods: This study was conducted over a period of six months. All male and female subjects of age group 30-40 receiving anti-psychotic medications for a minimum of 1 year before the study starts and who were noncompliant to the prescribed medications were included. Results: Females were prominent in the non-adherent group and males were found to be higher in Group-B. Most of the schizophrenic patients were suffering with paranoid schizophrenia, living in the urban environment and running their nuclear families. Majority of the Subjects in the non-adherent group were illiterates and unemployed, where as in the dose titration group many have completed their primary education and were employed. Compared to first generation antipsychotics, second generation antipsychotic drugs were most commonly prescribed. Almost 56.07% do not have the support from their families. The main reasons stated by the patients to be noncompliant were difficulty in access to treatment, financial obstacles, forgetfulness. Dose titrations were made at an interval of 1 month for four antipsychotics (haloperidol, chlorpromazine, olanzapine and risperidone) and patients were benefited by the titration which was observed through the PANSS scores at each visit. Conclusion: Findings suggest that there is a need for identification and reduction of factors responsible for noncompliance. Strategies to improve adherence have the potential to reduce these costs. Dose titration shows beneficial effect to improve patient quality of life. Hence they should be implemented in clinical practice depending upon the individual patient.

scholarly journals Psychiatric Co-Morbidity and Substance Use Correlated with Medication Adherence Among People Living with HIV (PLWHIV) Attending the Virology Clinic of the University of Port Harcourt Teaching Hospital (UPTH)

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Nkporbu A. K ◽  
Ayodeji O.A
Keyword(s):  
Substance Use ◽  
Medication Adherence ◽  
Teaching Hospital ◽  
Rating Scale ◽  
Health Concern ◽  
People Living With Hiv ◽  
Port Harcourt ◽  
Co Morbidity ◽  
The University ◽  
Living With Hiv

HIV infection is an endemic communicable chronic disease, of enormous public health concern worldwide particularly, Sub-Saharan African. Substance use and associated psychiatric co-morbidity among the sufferers may affect medication adherence. The aim of this study, therefore, was to determine the effect of psychiatric comorbidity and substance use on medication adherence among people living with HIV at the University of Port Harcourt Teaching Hospital. A cross-sectional study was conducted among 230 Subjects Living with HIV. Sociodemographic questionnaire was used. A structured questionnaire was used to assess use of psychoactive substances. Psychiatric co-morbidity was assessed using the GHQ-12 in conjunction with the DSM 5. The Medication Adherence Rating Scale (MARS) was used to assess medication adherence. Data was analysed using the SPSS version 20. The prevalence of psychological co-morbidity among PLWHIV was 30.6%. Alcohol use disorders was the highest with 73 (31.7%), followed by cigarette smoking 38 (16.5%) while nicotine snuffing was the least with 1 (0.4%). Of the 43 (18.7%) with poor medication adherence, 31 (15.2%) had psychiatric co-morbidity, 26 (11.3%) had substance use, 25 (10.8%) had both psychiatric and substance use co-morbidity while 19 (8.2%) had none (p=0.004). Psychological co-morbidity and substance use are prevalent among PLWHIV, and may affect medication adherence.

scholarly journals To Assess the Effectiveness of Psycho Education on Medication Adherence among Schizophrenic Patients

2021 ◽  
pp. 656-661
Author(s):  
Samuel Vanlalpeka ◽  
Sr. Tessy Sebastian ◽  
Jaya Gawai ◽  
Pooja Kasturkar
Keyword(s):  
Medication Adherence ◽  
Rating Scale ◽  
Sampling Technique ◽  
Research Approach ◽  
Adherence Score ◽  
Post Test ◽  
Patient Will ◽  
Long Time ◽  
Schizophrenic Patients ◽  
Test Level

Background: Schizophrenia is one of the most leading perplexing complications, that creates a problem in an individual in which there is a disturbance in their thinking, emotion, and volition in the presence of their clear consciousness. Rehospitalization and reoccurrence of the symptoms are very common among these patients if medication is not taken properly. Objective: 1) To assess pre test level of medication adherence among Schizophrenic patients. 2) To assess the effectiveness of psycho education on medication adherence among Schizophrenic patients after intervention. 3) To evaluate the effectiveness of psycho education on medication adherence among Schizophrenic patients. 4) To associate the post test level of psycho education on medication adherence score with their selected demographic variables. Methodology: It is an interventional research approach study, and it will be conducted among 60schizophrenic inpatients who were selected by using a non-probability purposive sampling technique in psychiatric departments at Acharya Vinoba Bhava Rural Hospital, Sawangi (Meghe), Wardha. A standardized Medication Adherence Rating Scale (MARS) will be used to collect the data. Expected Outcome: It is expected that the psycho education given to the patient will be effective and thus improve their medication adherence. Conclusions: Medication non-adherence is not a recent problem among schizophrenic patients; it is a problem that remains for a long-time. This study thus will provide recent data regarding the effectiveness of psycho education among schizophrenic patients.

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