Sexual dysfunctions and treatment compliance in individuals with psychotic disorder

IntroductionSexual dysfunctions are more common in individuals with psychotic disorders and has a major impact on both quality of life and compliance.ObjectivesThe purpose of this study is to investigate whether a relationship between sexual dysfunction and level of treatment compliance in individuals with psychotic disorders.MethodsThe sample group of the study consisted of 173 in-patients who agreed to participate were selected by random sampling method. The permission was obtained from the hospital's ethics committee. In this study, to assess the sexual functionality Golombok-Rust inventory of sexual satisfaction male and female form and to assess the treatment compliance; medical treatment compliance rate scale is used.ResultsWhen sexual problems and treatment compliance compared to gender, subscales of satisfaction (t = 4,423, P = 0.000), avoidance (t = 3.348, P = 0.001), touch (t = 2.165, P = 0.032) and overall total (t = 4.015, P = 0.000), although a statistically significant difference was found, there were no differences in treatment compliance. Aditionally, there is no relation between sexual problems and treatment compliance in men. It is also found that there is a weak negative statistical relation amongst treatment compliance and communication (r = −0.244, P = 0.027), avoidance (r = −0.270, P = 0.014), anorgasmia (r = −0.253, P = 0.022) and overall total (r = −0.249, P = 0.024) in women. According to these findings while sexual problems increase, treatment compliance decreases.ConclusionsThe level of compliance to the treatment and subscales of sexual problems; satisfaction, avoidance, and touch mean scores differ from each other. There was a weak negative correlation in between Women's compliance and sexual problems.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Psychiatric comorbidities in temporal lobe epilepsy: A case study

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.549 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S474-S474

Author(s):

L. Jouini ◽

U. Ouali ◽

R. Zaouche ◽

R. Jomli ◽

Y. Zgueb ◽

...

Keyword(s):

Temporal Lobe Epilepsy ◽

Temporal Lobe ◽

Psychotic Disorders ◽

Psychiatric Symptoms ◽

Complete Disappearance ◽

Therapeutic Implications ◽

Self Harm ◽

Competing Interest

IntroductionPsychiatric disorders frequently occur in patients with temporal lobe epilepsy (TLE) (70%). This combination further reduces the quality of life of patients as diagnosis is difficult and therapeutic opportunities are often missed.ObjectivesThe aim of this case study is to show the possible association between TLE and psychiatric semiology and its therapeutic implications.MethodsPresentation of the clinical case of Mr BH who experienced psychosis like symptoms, was finally diagnosed with TLE and put under anti-epileptic drugs.ResultsMr BH, aged 22, with no family or personal history, was admitted for aggressive behavior, self-harm, pyromania, and depression. Three years prior to onset of psychiatric symptoms, he reports episodes of pulsatile- left-temporal headache followed by hypertonic movements of the neck. Symptoms were intermittently followed by total amnesia or impaired consciousness. The patient explained symptoms by an inner presence that he called “his twin” and to whom he attributed those behaviors contrary to his will. The discovery of bilateral hippocampal atrophy in magnetic resonance imaging with a normal electroencephalography suggested the diagnosis of TLE with post-ictal psychotic disorders. Patient was put initially on diazepam and olanzapine with partial improvement. Association of valproate led to progressive but then complete disappearance of symptoms and so confirmed our diagnosis.ConclusionsIt is often difficult to attach psychiatric symptoms to epilepsy. The diagnosis should be done on a set of clinical, radiological and electrical arguments.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Insight and aggressive Behavior in acute Schizophrenic Patients

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.1602 ◽

2016 ◽

Vol 33 (S1) ◽

pp. S441-S441

Author(s):

S. Campi ◽

C. Esposito ◽

P. andreassi ◽

P. Bandinelli ◽

P. Girardi ◽

...

Keyword(s):

Aggressive Behavior ◽

Treatment Compliance ◽

Aggressive Behaviors ◽

Self Monitoring ◽

Poor Treatment ◽

Schizophrenic Patients ◽

Competing Interest ◽

The Relationship ◽

Acute Patients

Introductionaggressive behavior in wards is associated to poor treatment compliance and low clinical insight. Most studies focused on the clinical and cognitive dimensions of insight, while the relationship between metacognitive dimension and aggressive behaviors was not investigated. Our aim was to understand what relationship occurs between dimensions of insight (metacognitive, cognitive, clinical), and specific aggressive behaviors in acute patients.Methodswe recruited 75 acute schizophrenic patients using: aQ; MO aS; IS; P aNSS; BCIS.Resultsa positive correlation between the IS score and the hostility, angry and physical aggression sub-scores of the aQ was highlighted, while no correlation between the score of IS and MO aS total score was found. No correlation between the score of the P aNSS G12 item and the aQ scores and MO aS was found, and no correlation between BCIS scores, MO aS and aQ scores was found.Conclusionsin our patients, a higher level of metacognitive insight, but not clinical nor cognitive insight, was associated to higher levels of hostility. we suggest that a higher ability to monitor and appraise one's own altered processes of thought and related discomfort, feeling of destabilization and loss of control, could contribute to enhance resentment and suspiciousness. Findings help develop specific therapeutic strategies to enhance metacognitive and self-monitoring abilities, helping patient's understanding of the illness, improving compliance with treatment, and patient's quality of life. Our results support the multidimensional nature of insight in schizophrenia, confirming that clinical, cognitive and metacognitive dimensions are independent though related facets of the phenomenon of insight in schizophrenia.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Effectiveness of long-acting aripiprazole in schizoaffective disorders: A naturalistic longitudinal study

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.1416 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S757-S757

Author(s):

A. Nivoli ◽

M. Antonioli ◽

L. Folini ◽

L. Floris ◽

G. Meli ◽

...

Keyword(s):

Quality Of Life ◽

Schizoaffective Disorder ◽

Rating Scale ◽

Psychiatric Clinic ◽

Significant Difference ◽

Sample Test ◽

Competing Interest ◽

Long Acting ◽

Over Time

IntroductionIntramuscular paliperidone palmitate (PP) is a long-acting, atypical anti-psychotic for once monthly intramuscular (IM) administration in the treatment of patients with schizophrenia.ObjectiveTo study the effectiveness (efficacy and quality of life) of ARP in the maintenance treatment of schizoaffective disorder.MethodsA non-randomized, prospective naturalistic study was performed in out-patients with schizoaffective disorder unsuccessfully treated with oral anti-psychotics. Efficacy of ARP over time was evaluated by using brief psychiatric rating scale (BPRS 24-items), quality of life was evaluated by using QL-Index, both at T0 and at most recent visit (T1). Data were analyzed with Student's t-tests and Pearson correlations (α value, two tailed). Paired t-test was applied for BPRS and for Ql-Index total scores (T0–T1).ResultsData were available for 8 outpatients consecutively prescribed ARP and naturalistically treated attending at the psychiatric clinic, university of Sassari. Mean time on ARP treatment was 207.14 days (sd 137.2). BPRS mean total score at T0 was 57 (sd 13.2) and at T1 was 39.7 (sd 10.8). QL-Index mean total score was at T0 5.43 (sd 1.6) and at T1 7.14 (sd 2.7). Paired sample test showed a statistically significant difference in decreasing symptoms at BPRS over time (P = 0.001) and QL-Index total score (P = 0.023). The analyses showed a significant improving at the following BPRS sub-items: anxiety (P = 0.005), mood elevation (P = 0.014) conceptual disorganization (P = 0.048), emotional withdrawal (P = 0.05), tension (P = 0.02) and distractibility (P = 0.03).Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Comparison of Creativity and Self-Esteem in Students with Employed and Household Mothers

International Education Studies ◽

10.5539/ies.v10n2p63 ◽

2017 ◽

Vol 10 (2) ◽

pp. 63

Author(s):

Maryam Safara ◽

Zeinab Blori Alkaran ◽

Mojtaba Salmabadi ◽

Najmieh Rostami

Keyword(s):

University Students ◽

Undergraduate Students ◽

Sampling Method ◽

Self Esteem ◽

T Test ◽

Quality Of Education ◽

Statistical Population ◽

Significant Difference ◽

The University

Objective: The present study was carried out to compare creativity and self-esteem in the university students with employed and household mothers in academic years 2014-2015. Method: This research is a descriptive one which is of comparative-casual type. The statistical population includes all undergraduate students of Azad universities of Roudhen, Shahr-e Ray Central Tehran and national universities of Al-Zahra, Shahid Beheshti and Vali-e Asr that among them 240 students (120 males and 120 females) were selected by random and available sampling method. To collect the data, Arjmand’s (2003) questionnaire of creativity and Copper-Smith’s (1967) self-esteem questionnaire were used. To test the hypotheses, independent t-test was used. Findings: The results showed that there is a significant difference between self-esteem in students with employed and household mothers. Also, a significant difference was not observed between the rate of creativity in students with employed and household mothers. Conclusion: The results of the present research can be used to provide proper strategies for mothers, instructors, and those who are relevant with educational affairs to enhance the quality of education, to nurture and flourish creativity and self-esteem in individuals.

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Prescription profile of antipsychotics in inpatients with psychotic disorders

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.2289 ◽

2016 ◽

Vol 33 (S1) ◽

pp. S612-S612

Author(s):

M.D.C. García Mahía ◽

Á. Fernández Quintana ◽

M. Vidal Millares

Keyword(s):

Psychotic Disorders ◽

Treatment Resistance ◽

Psychiatric Inpatients ◽

Total Sample ◽

Response To Treatment ◽

Typical Antipsychotic ◽

Concurrent Use ◽

Significant Difference ◽

Schizophrenic Patients ◽

Competing Interest

IntroductionPrevious studies of prescribing in psychiatric services have identified the relatively frequent use of combined antipsychotics in schizophrenia.Aims– To analyze the proportion of patients treated with more than one antipsychotic;– to study clinical as sociodemographic variables associated with types of prescription.MethodsRetrospective descriptive study of treatment prescribed to psychiatric inpatients treated in an acute care unit of Psychiatry Service in a large teaching hospital during a period of 3 years. Consecutively admitted inpatients receiving concurrent antipsychotics were compared with those treated with a single antipsychotic. Prescription drug records at discharging were revised, n = 263.ResultsFrom the total sample, 61% received more than one antipsychotic. The most common types of combinations were atypical plus a typical antipsychotic followed by two atypical antipsychotics, being less frequent combination of three or more antipsychotics. There were 19 different drug combinations. Concurrent antipsychotics were most frequently prescribed in schizophrenia and schizoaffective disorder. Patients with more previous episodes of illness received more frequently concurrent antipsychotics than patients with low number of previous episodes of illness (P < 0.03). Patients with longer time of hospitalization, and age between 30 and 50 years were treated more frequently with several antipsychotics. Analysis with other variables is presented in the study.ConclusionsThere is a significant difference in the strategies of treatment with antipsychotics depending on diagnosis and number of previous episodes of illness. The concurrent use of multiple antipsychotics in psychiatric inpatients appears to be a response to treatment resistance and is frequent in schizophrenic patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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The use of Polygenic Risk Scores to Inform Aetiology of Mood and Psychotic Disorders

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.2051 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S166-S166

Author(s):

J. Harrison ◽

S. Mistry

Keyword(s):

Bipolar Disorder ◽

Genetic Basis ◽

Psychotic Disorders ◽

Mental Illnesses ◽

Risk Scores ◽

Psychotic Symptoms ◽

Polygenic Risk ◽

Genetic Overlap ◽

Competing Interest

IntroductionPolygenic risk scores (PRS) incorporate many small genetic markers that are associated with conditions. This technique was first used to investigate mental illnesses in 2009. Since then, it has been widely used.ObjectivesWe wanted to explore how PRS have been used to the study the aetiology of psychosis, schizophrenia, bipolar disorder and depression.AimsWe aimed to conduct a systematic review, identifying studies that have examined associations between PRS for bipolar disorder, schizophrenia/psychosis and depression and psychopathology-related outcome measures.MethodsWe searched EMBASE, Medline and PsychInfo from 06/08/2009 to 14/03/2016. We hand-searched the reference lists of related papers.ResultsAfter removing duplicates, the search yielded 1043 publications. When irrelevant articles were excluded, 33 articles remained. We found 24 studies using schizophrenia PRS, three using bipolar PRS and nine using depression PRS. Many studies successfully used PRS to predict case/control status. Some studies showed associations between PRS and diagnostic sub-categories. A range of clinical phenotypes and symptoms has been explored. For example, specific PRS are associated with cognitive performance in schizophrenia, psychotic symptoms in bipolar disorder, and frequency of episodes of depression. PRS have also demonstrated genetic overlap between mental illnesses. It was difficult to assess the quality of some studies as not all reported sufficient methodological detail.ConclusionsPRS have enabled us to explore the polygenic architecture of mental illness and demonstrate a genetic basis for some observed features. However, they have yet to give insights into the biology, which underpin mental illnesses.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Dyadic Satisfaction and Shared Affectivity Are Associated with Psycho-Sexual Functioning in Elderly Men and Women

Sexes ◽

10.3390/sexes3010006 ◽

2022 ◽

Vol 3 (1) ◽

pp. 68-77

Author(s):

Erika Limoncin ◽

Daniele Mollaioli ◽

Andrea Sansone ◽

Elena Colonnello ◽

Giacomo Ciocca ◽

...

Keyword(s):

Sexual Health ◽

Elderly People ◽

Linear Regression Analysis ◽

Sexual Life ◽

Elderly Subjects ◽

Sexual Dysfunctions ◽

Emotional Wellbeing ◽

Significant Difference ◽

Dyadic Satisfaction

Objectives The quality of sexual life of elderly people represents an understudied topic of sexual medicine and of psycho-sexology. Hence, we aimed to evaluate the association of specific psycho-relational variables, such as intimacy, increased affective gestures towards a partner (AGtP), daily shared activities, and dyadic satisfaction, with the psychosexual wellbeing of elderly people, expressed in terms of sexual satisfaction. Methods: A cohort of elderly people was selected from a sample of a broader study evaluating the role of sexual activity in protecting the emotional wellbeing of a population subjected to quarantine due to the COVID-19 pandemic. Specifically, the presence of sexual dysfunctions, the emotional wellbeing (i.e., absence of anxiety and/or depression), and the quality of the partners’ relationships were studied. For the study’s purpose, the Sexual Health Inventory for Males (SHIM), the Female Sexual Function Index (FSFI), the Orgasmometer and the Orgasmometer-F, the Generalized Anxiety Disorder scale (GAD-7), the Patient Health Questionnaire (PHQ-9), and the Dyadic Adjustment Scale were adopted. Results: A group of 124 elderly subjects (≥60) was selected for the study’s purposes. Among these, 84% were males (120/124), and 16% were females (20/124). All the subjects declared to be in a stable relationship and to be sexually active during the first lockdown period. Gender differences were found for the Dyadic Satisfaction subscale (males: 37.04 ± 6.57; females: 32.85 ± 10.04; p < 0.05) and the Orgasmometer (males: 7.64 ± 1.30; females: 6.60 ± 2.46; p < 0.01). Linear regression analysis showed the association between higher Orgasmometer scores and: (i) the absence of sexual dysfunctions (β = −1.213; SE = 0.271; p < 0.0001), (ii) higher dyadic satisfaction (β = 0.042; SE = 0.019; p < 0.05), and (iii) reduced shared activities with partner (β = −0.463; SE = 0.143; p < 0.01) and increased affective gestures towards partner (DAS measured AGtP) (β = 0.595; SE = 0.065; p < 0.0001). Post hoc analysis of ANCOVA with the Bonferroni correction method showed a significant difference in the Orgasmometer scores between subjects with and without sexual dysfunction (mean difference: 2.102; SE = 0.340; pBonf < 0.001), with healthy subjects reporting higher scores compared to dysfunctional ones. Conclusions: It is reasonable to suppose that, beyond the presence of sexual dysfunctions, the sexual health of elderly people may benefit from the quality of the relationship, and, specifically, from the presence of affective gestures towards the partner and the dyadic satisfaction. To the contrary, the quantity of time spent together, sharing specific activities, may be considered a factor worsening relational and sexual health. These data should be considered during the evaluation of sexual health among elderly people.

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Clinical experience with aripiprazole long-acting injection

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.615 ◽

2016 ◽

Vol 33 (S1) ◽

pp. s243-s244

Author(s):

M.P. Calvo Rivera ◽

B. Girela Serrano ◽

A. Porras Segovia ◽

L. Gutiérrez Rojas

Keyword(s):

Clinical Evaluation ◽

Psychotic Disorders ◽

Good Health ◽

Health Condition ◽

Sf 36 ◽

Monthly Injection ◽

Competing Interest ◽

Long Acting ◽

And Function

IntroductionAripiprazole long-acting injection is the latest long-acting injectable (LAI) antipsychotic medication released in the market which requires a monthly injection.ObjectivesThe aim of our study is to present our experience in the use of Aripiprazole long-acting injection as maintenance therapy in patients with schizophrenia and other psychotic disorders.MethodologyOur sample consists of 20 patients who started treatment with long acting aripiprazole during the last 6 months of its release. Validated scales for collecting information on sociodemographic, clinical evaluation (CGI scale), quality of life (health questionnaire SF-36) and function (Sheehan Disability Inventory and social relationship scale SBS) were used.ResultsThe health condition of the patients was generally good and 68% reported feeling better than during the last year. Social functioning was adequate (level 1 or 2) in about 70% of the patients. Social, employment and family's disability was mild in 57% of cases, the average stress’ perception was 23% and the average social support perception was 72%. Regarding the clinical evaluation, in comparison to the initiation of the treatment 18% of the patients were slightly better, 45% moderately better and 36% much better.ConclusionA remarkable clinical improvement was observed, maintaining good health, with an acceptable level of functionality. This study shows that the incorporation of long-acting Aripiprazole to the treatment of our sample has been a significant improvement in overall functioning of the patient.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Frequency of Sexual Problems and Related Psychosocial Characteristics in Cancer Patients—Findings From an Epidemiological Multicenter Study in Germany

Frontiers in Psychology ◽

10.3389/fpsyg.2021.679870 ◽

2021 ◽

Vol 12 ◽

Author(s):

Svenja Heyne ◽

Peter Esser ◽

Kristina Geue ◽

Michael Friedrich ◽

Anja Mehnert-Theuerkauf

Keyword(s):

Quality Of Life ◽

Social Support ◽

Cancer Patients ◽

Psychosocial Factors ◽

Multicenter Study ◽

Age Groups ◽

Well Being ◽

Sexual Problems ◽

Significant Difference

BackgroundMultimodal cancer treatments are often associated with sexual problems. Identifying patients with sexual problems could help further elucidate serious issues with their sexuality and thus promote or maintain patients’ sexual health. We aimed to assess the occurrence of sexual problems in patients across different tumor locations and to explore associated sociodemographic, medical and psychosocial factors.MethodsWe included 3,677 cancer patients (mean age 58 years, age range 18–75 years, 51.4% women) from a large epidemiological multicenter study in Germany on average 13.5 months after cancer diagnosis. The occurrence and frequency of sexual problems were assessed via a binary item on the problem checklist of the Distress Thermometer (DT). Controlled associations of these problems with sociodemographic, medical and psychosocial factors including distress (DT), anxiety (GAD-7), depression (PHQ-9), quality of life (EORTC-QLQ-C30), and social support (SSUK-8) are analyzed using logistic regression analysis.ResultsWe found that 31.8% of patients reported sexual problems, with a significant higher proportion in men (40.5%) compared to women (23.7%), OR 2.35, 95% CI [1.80–3.07] and a higher proportion in patients with a partner (35.6%) compared to those without a partner (3.5%), OR 2.83, 95% CI [2.17–3.70]. Tumor location was associated with occurrence of sexual problems: patients with cancer, affecting the male genital organs had the highest chance for sexual problems, OR 2.65, 95% CI [1.18–3.95]. There was no significant difference in the occurrence of sexual problems between age groups OR 0.99, 95% CI [2.13–3.53] and type of therapy (e.g., operation OR 0.91, 95% CI [0.72–1.15]). Sexual problems were further associated with elevated levels of anxiety, OR 1.05, 95% CI [1.02–1.10], less social support, OR 0.93, 95% CI [0.90–0.97] and lower quality of life in terms of impaired functioning (e.g., social function, OR 0.99, 95% CI [0.99–1.00]).ConclusionsSexual problems are commonly reported by patients. Male patients and those living with a partner are more likely to report sexual problems. Sexual problems are associated with different aspects of well-being. The findings imply the practical relevance to screen for sexual problems among patients and identified groups that should be particularly monitored.

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Analisis Perbedaan Penggunaan Metode Pengakuan Pendapatan Margin Murabahah Terhadap Kualitas Laba (Studi Kasus pada Bank Syariah di Indonesia Tahun 2011-2013)

Jurnal Ekonomi Syariah Teori dan Terapan ◽

10.20473/vol3iss20169pp699-712 ◽

2017 ◽

Vol 3 (9) ◽

pp. 699

Author(s):

Dwi Wulan Ramadani ◽

Noven Suprayogi

Keyword(s):

Earnings Management ◽

Sampling Method ◽

Earnings Quality ◽

Statistical Test ◽

Annual Reports ◽

Islamic Banks ◽

Revenue Recognition ◽

Recognition Method ◽

Significant Difference

This study aims to determine the presence or absence of differences in the earnings quality on murabaha margin revenue recognition. The sample used in this study selected by purposive sampling method. It produces 6 Islamic Banks (BUS) in Indonesia with the data obtained from their annual reports that have already been published. The research used a quantitative approach using equations of regression to detect the presence or absence of earnings management, which then in different test using independent t-test. The variable in this study is earnings quality that is categorised based on the use of murabaha margin revenue recognition method. Results shows that differences in using murabaha margin revenue recognition method has an impact on quality of earnings. However, the statistical test indicated that there was no significant difference to the quality of earnings.

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