Principal component analysis of routine blood test results with Parkinson's disease: A case-control study

2021 ◽  
Vol 144 ◽  
pp. 111188
Author(s):  
Yuling Wang ◽  
Hua Gao ◽  
Sen Jiang ◽  
Qin Luo ◽  
Xuejie Han ◽  
...  
Keyword(s):  
Principal Component Analysis ◽  
Blood Test ◽  
Case Control Study ◽  
Principal Component ◽  
Component Analysis ◽  
Case Control ◽  
Test Results ◽  
Routine Blood ◽  
Routine Blood Test ◽  
Control Study

scholarly journals Clinical Signs and Blood Test Results Among Humans Infected With Zoonotic Simian Foamy Virus: A Case-Control Study

2018 ◽  
Author(s):  
Florence Buseyne ◽  
Edouard Betsem ◽  
Thomas Montange ◽  
Richard Njouom ◽  
Chanceline Bilounga Ndongo ◽  
...  
Keyword(s):  
Blood Test ◽  
Case Control Study ◽  
Foamy Virus ◽  
Clinical Signs ◽  
Case Control ◽  
Test Results ◽  
Simian Foamy Virus ◽  
Control Study

scholarly journals Dietary Pattern in Relation With CRC Risk Among Moroccan Population; A Multicenter Case-Control Study

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 11s-11s
Author(s):  
H.A. Boudouaya ◽  
K. Elkinany ◽  
M. Sidi Deoula ◽  
Z. Hatime ◽  
A. Elasri ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Principal Component Analysis ◽  
Olive Oil ◽  
Dairy Products ◽  
Case Control Study ◽  
Principal Component ◽  
Case Control ◽  
Dietary Factors ◽  
Study Population ◽  
Control Study

Background: Colorectal cancer (CRC) is a global public health problem, an estimated of 1.4 million cases were diagnosed worldwide in 2012. Studies in health and nutrition confirmed that dietary factors were strongly associated with CRC risk. Aim: The objective of this empirically study was to reveal unobserved dietary profiles that were associated favorably or unfavorably with CRC risk in Moroccan study population. Methods: This case-control study included a total of 2906 participants in five centers, 1453 cases and 1453 controls, and was gender, age and center matched. Statistical exploratory data reduction methods were performed in this study population based on a specific scientific hypothesis linking dietary behavior and colorectal cancer risk. Principal component analysis (PCA) was applied separately in cases and in controls as individuals and with FFQ nutritional group's heads items as variables. The correlation matrix of food variables was examined to explain most of the variation in the data, reducing a large number of food variables to a smaller set that captures the major dietary factors differences in Moroccan population. Results: Three alimentary profiles were identified for controls based on three principal component analysis, which the first one was highly positive with high cereals, fruits and nuts, legumes, fish, olive oil, dairy products and legumes consumption, and was highly negative with an increasing consumption of poultry and red meat. This component explained 26.5% of the variance in initial data and described a healthy pattern characterized with high fiber intake. In opposite, five principal components were identified for cases that indicated five nutritional profiles with a predominance of dairy products, nuts, fish consumption and low legumes, olive oil and fruits intake: its explained 15.37% of total variance. Conclusion: PCA analysis is a multidimensional factor analysis method that was used in this epidemiologic study to describe the variance in our big database in relation with CRC risk among Moroccan people. This method needs a supervised analysis such as linear discriminant analysis (LDA) to give interpretation and prediction models of CRC risk related to nutritional behavior among this study population.

scholarly journals Predictive Value of Routine Blood Test in patients with Early Esophageal Cancer: A Matched Case-Control Study

2021 ◽  
Vol 12 (15) ◽  
pp. 4739-4744
Author(s):  
Xiaoying Zhou ◽  
Han Chen ◽  
Weifeng Zhang ◽  
Xueliang Li ◽  
Xinmin Si ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Predictive Value ◽  
Blood Test ◽  
Case Control Study ◽  
Case Control ◽  
Early Esophageal Cancer ◽  
Routine Blood ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Suspected cancer symptoms and blood test results in primary care before a diagnosis of lung cancer: a case–control study

2019 ◽  
Vol 15 (33) ◽  
pp. 3755-3762 ◽  
Author(s):  
Laura McDonald ◽  
Robert Carroll ◽  
Akash Harish ◽  
Nikhil Tanna ◽  
Faisal Mehmud ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Blood Test ◽  
Case Control Study ◽  
Case Control ◽  
Test Results ◽  
Cancer Symptoms ◽  
Lung Cancer Patients ◽  
Diagnosis Of Lung Cancer ◽  
Control Study

Aim: To compare symptoms and blood test results prior to cancer diagnosis in individuals who developed lung cancer and those who did not. Patients & methods: Nested case–control study, lung cancer patients were matched to up four controls with no record of cancer. Differences in symptoms and blood test results were investigated in the 2-year period prior to diagnosis. Results: 26,379 lung cancer patients were matched to 92,125 controls. Elevated C-reactive protein (CRP) was independently predictive of lung cancer at every 2-month interval 12 months prior to diagnosis. Elevated CRP in conjunction with at least one symptom was associated with greater than fourfold higher odds of lung cancer. Conclusion: CRP may be a prediagnostic marker for lung cancer, and when present with other symptoms could facilitate the investigation of high-risk individuals.

scholarly journals FAKTOR YANG MEMPENGARUHI PENERAPAN INISIASI MENYUSU DINI (IMD) DI WILAYAH KERJA PUSKESMAS JUMPANDANG BARU KOTA MAKASSAR

2020 ◽  
Vol 15 (2) ◽  
pp. 207
Author(s):  
Nurjaya Nurjaya ◽  
Djuhadiah Saadong ◽  
Subriah Subriah
Keyword(s):  
Health Center ◽  
Case Control Study ◽  
Case Control ◽  
The Philippines ◽  
Breastfeeding Initiation ◽  
Test Results ◽  
Birth Attendants ◽  
Consecutive Sampling ◽  
Control Study

ABSTRAK Latar Belakang :  IMD sangat bermanfaat bukan hanya bagi bayi yang baru lahir tetapi juga bagi ibu yang melakukan IMD. Jika bayi berada dalam dekapan ibu, maka bayi tersebut dengan sendirinya merangkak ke payudara ibu dan akan mulai menghisap puting susu ibunya. Data menunjukkan bahwa di Indonesia, persentase pemberian Air Susu Ibu (ASI) dalam 1 jam pertama setelah bayi dilahirkan masih rendah yaitu sebesar 38%. Angka tersebut masih jauh tertinggal bila dibandingkan dengan negara-negara berkembang lainnya seperti Oman (85%), Srilangka (75%), Filipina (54%), dan Turki (54%)(SDKI 2017). Oleh karena itu tujuan dari penelitian ini adalah untuk Mengetahui faktor yang mempengaruhi penerapan inisiasi menyusu dini di wilayah kerja Puskesmas Jumpandang Baru Makassar tahun 2018..Jenis penelitian ini: Penelitian ini menggunakan desain case control study. Populasi pada penelitian ini adalah semua ibu yang melahirkan di Wilayah kerja Puskesmas Jumpandang Baru. Pengambilan sampel dilakukan dengan Consecutive Sampling yaitu dengan perbandingan 1 : 2 yang dibutuhkan adalah 30 kasus dan 60 kontrol.. Pengumpulan data dilakukan menggunakan lembaran kuesioner. Data dianalisis secara univariat, bivariat dan multivariat dengan menggunakan uji Regresi Berganda LogistikHasil penelitian : Ada pengaruh pengetahuan ( OR = 5,5), peran bidan/penolong persalinan (OR = 12,571), dukungan dari suami ( OR = 3,3) terhadap penerapan inisiasi menyusu dini dan Hasil uji multivariat menunjukkan bahwa variabel peran bidan/penolong persalinan merupakan faktor yang paling berpengaruh terhadap penerapan inisiasi menyusu dini dengan nilai Wald sebesar 13 dan signifikansi sebesar 0,010.Kesimpulan : Terdapat pengaruh pengetahuan, peran bidan/penolong persalinan , dukungan dari suami terhadap penerapan inisiasi menyusu dini, dan variable peran bidan/penolong persalinan yang paling berpengaruh terhadap penerapan inisiasi menyusu dini. Kata Kunci: Penerapan Inisiasi Menyusu DiniABSTRACT Background: IMD is very beneficial not only for newborns but also for mothers who do IMD. If the baby is in the mother's arms, the baby naturally crawls into the mother's breast and will start sucking her mother's nipples. Data shows that in Indonesia, the percentage of breastfeeding in the first 1 hour after the baby is born is still low at 38%. This figure is far behind when compared to other developing countries such as Oman (85%), Sri Lanka (75%), the Philippines (54%), and Turkey (54%) (IDHS 2017) . Therefore the purpose of the research This is to find out the factors that influence the application of early breastfeeding initiation in the working area of the Jumpandang Baru Makassar Health Center in 2018 ..Type of research: This study uses a case control study design. The population in this study were all mothers who gave birth in the Working Area of the Jumpandang Baru Health Center. Sampling was done by Consecutive Sampling, which is a ratio of 1: 2. It takes 30 cases and 60 controls. Data collection is done using a questionnaire sheet. Data were analyzed by univariate, bivariate and multivariate using the Multiple Logistic Regression testResults: There was influence of knowledge (OR = 5,5), role of midwife / birth attendant (OR = 13), support from husband (OR = 3,3) on the application of early breastfeeding initiation and multivariate test results showed that the role of midwives / birth attendants was a factor the most influential on the application of early breastfeeding initiation with a Wald value of 12,956 and a significance of 0.010.Conclusion: There is an influence of knowledge, the role of midwives / birth attendants, support from husbands on the application of early breastfeeding initiation, and the role variables of midwives / birth attendants who most influence the application of early breastfeeding initiation. Keywords: Application of Early Breastfeeding Initiation 

scholarly journals Is Opium Use Associated with an Increased Risk of Lung Cancer? A Case-Control Study

2019 ◽  
Author(s):  
Ahmad Naghibzadeh-Tahami ◽  
Maryam Marzban ◽  
Vahid Yazdi-Feyzabadi ◽  
Shahryar Dabiri ◽  
Reza Abbasi Rayeni ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Case Control Study ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Test Results ◽  
Increased Risk ◽  
Study Support ◽  
Control Study ◽  
Opium Use ◽  
Structured Questionnaire

Abstract Background: In recent years, lung cancer (LC) incidence has increased in Iran. The use of opium and its derivatives (O&D) has increased as well. The aim of this study was to investigate the association between the use of O&D and LC incidence. Methods: In this case-control study conducted in Kerman, Iran; 140 patients with lung cancer and 284 healthy controls matched by age, sex, and place of residence were included. Data including O&D use, cigarette smoking, alcohol use, and diet were collected using a structured questionnaire. The relation between the use of O&D and LC was evaluated using conditional logistic regression test. Results: The use of opium was associated with an increased risk of LC (Adjusted Odds Ratio (AOR) = 7.95, 95% CI: 3.78 -16.73). A significant dose-response relation between the use of opium and its derivatives was observed (low use AOR = 7.47, 95% CI: 2.33-23.98 and high use AOR = 11.57, 95% CI: 2.25-59.49). Also, there was a relation between starting to use O&D at lower ages and an increased risk of LC (AOR = 5.78, 95 % CI: 2.36 - 14.14). Conclusion: The results of this study support that opium use could be considered as a strong risk factor for LC. Thus, it is highly suggested that tailored policies to be applied in order to reduce use of opium.

A healthy dietary pattern may be associated with primary insomnia among Iranian adults: A case-control study

2020 ◽  
pp. 1-12
Author(s):  
Samaneh Sadat ◽  
Ammar Salehi-sahlabadi ◽  
Makan Pourmasoumi ◽  
Awat Feizi ◽  
Cain C. T. Clark ◽  
...  
Keyword(s):  
Dietary Patterns ◽  
Dietary Pattern ◽  
Case Control Study ◽  
Principal Component ◽  
Severity Index ◽  
Case Control ◽  
Primary Insomnia ◽  
Health Centers ◽  
Control Study ◽  
Healthy Dietary Pattern

Abstract. Objective: While it has been reported that both foods and nutrients for individuals are connected with sleep, there is no evidence regarding the association of dietary patterns, identified by factor analysis, with primary insomnia. The present study sought to evaluate the association between major dietary patterns and the chance of having primary insomnia. Methods: The present case-control study was performed using 444 people (111 cases and 333 control), aged 18 to 60 years, referred to Isfahan health centers. Dietary intake was assessed via a food frequency questionnaire in a case-control study in Isfahan, Iran. Principal component analysis was used to determine major dietary patterns. The presence of primary insomnia was measured via the insomnia severity index questionnaire, and the subjects were grouped as healthy or insomniac. Results: Three major dietary patterns were recognized, and named; Western, Iranian Traditional and Healthy, respectively. The cumulative percentage of variance explained by three dietary patterns was 48.2%. Those in second (OR = 0.30; 95%CI: 0.2–0.46) and third (OR = 0.22; 95%CI: 0.15–0.35) tertiles of healthy dietary pattern were less likely suffer with insomnia. This association remained significant only in the highest tertile after adjusting potential confounders (OR = 0.45; 95%CI: 0.32–0.95). We found no significant association between greater adherence to Western or Iranian traditional dietary patterns and primary insomnia. Conclusions: The findings showed that although no statistically significant association was observed between both Western and Iranian traditional dietary patterns with primary insomnia, people with greater adherence to the healthy dietary pattern are less likely to have primary insomnia.

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