Associations of Cardiovascular Risk Factors With Antioxidative Capacity of High-Density Lipoproteins in Indigenous Australians

2018 ◽  
Vol 27 ◽  
pp. S408
Author(s):  
K. Takata ◽  
T. Shemesh ◽  
S. Kim ◽  
M. Duong ◽  
J. Lyons ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
High Density ◽  
High Density Lipoproteins ◽  
Indigenous Australians ◽  
Antioxidative Capacity

scholarly journals Fatores de Risco Cardiovascular e Medidas Antropométricas em Crianças e Adolescentes / Cardiovascular Risk Factors and Anthropometric Measures in Children and Adolescents

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Jayne Ramos Araujo Moura ◽  
Eugênio Barbosa de Melo Júnior ◽  
Mayara Vidal Torres Pimenta ◽  
Cyléa Abdalla de Miranda Silva ◽  
Ana Míria De Oliveira Batista ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Children And Adolescents ◽  
Cardiovascular Risk Factors ◽  
High Density ◽  
High Density Lipoproteins ◽  
Anthropometric Measures

O objetivo do estudo foi analisar a associação entre alterações nas medidas antropométricas e a frequência de fatores de risco cardiovascular em crianças e adolescentes. Estudo transversal, com amostra de 421 crianças e adolescentes. A coleta de dados foi realizada no período de agosto a novembro de 2014, por meio do preenchimento do formulário com informações referentes a identificação, aos aspectos socioeconômicos, às medidas antropométricas, à aferição da pressão arterial e de prática de atividades físicas, além de exames bioquímicos.Os principais resultados encontrados foram: 59,6% eram do sexo feminino, com idade média de 11,4 anos. Aqueles que apresentaram maiores índices de massa corporal e/ou circunferência da cintura alterada tinham mais chances de apresentar pressão arterial sistólica elevada, triglicerídeo elevado e high density lipoproteins – colesterol baixo.Conclui-se que aqueles que estavam acima do peso e/ou com excesso de adiposidade central apresentaram expressivas frequências de fatores de risco, como hipertensão arterial e desordens no perfil lipídico, para o desenvolvimento de doenças cardiovasculares.

scholarly journals Study of the high prevalence and cardiovascular risk factors: students aged 11 to 16 years from Caceres-Spain and Paranavaí-Brazil

2020 ◽  
Vol 37 (6) ◽  
pp. 372-378
Author(s):  
Walcir Ferreira-Lima ◽  
Silvia B Silva-Lima ◽  
Flávia E Bandeira-Lima ◽  
Fellipe Bandeira-Lima ◽  
Amanda Santos ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Blood Glucose ◽  
Cardiovascular Risk Factors ◽  
Fasting Blood Glucose ◽  
High Density ◽  
High Density Lipoproteins ◽  
General Obesity ◽  
A Value

Objective: to investigate the association of risk factors for the development of cardiovascular diseases in students from 11 to 16 years old in different contexts. Material and method: Sample composed by students of Cáceres - Spain (n = 165) and Paranavaí - Brazil (n = 237). Body Mass Index, level of physical activity, blood pressure, total cholesterol, low- and high-density lipoproteins, triglycerides and fasting blood glucose were analyzed. For the analysis of variables, the Kolmogorov-Smirnov tests, Student t, Mann-Whitney U, Chi-square, and Odds Ratio were used, with a 95% confidence interval, a value of p <0.05 was considered statistically significant. Results: Spanish students have higher average values of age, physical activity level, obesity in general, low- and high-density lipoproteins and fasting blood glucose (p <0.05). Brazilians had a greater accumulation of risk factors compared to the Spanish, specifically only 8.5% of Brazilians are exempt from RF compared to 28.2% of Spanish. It is observed that there is a higher prevalence of two RFs (G-BRA: 40.7% vs. G-ESP: 24.2%); and three or more RF (G-BRA 27.0% vs. G-ESP: 13.7%), considering a value of p <0.001. Being more active was associated with HDL levels among Brazilians. Although Spanish students had a higher prevalence of general obesity, they were more active. Conclusion: Spanish students showed better results in physical activity levels, fasting glucose concentration, high and low density lipoproteins, in addition to a lower number cardiovascular risk factors, despite being mainly from public schools; with higher average age and higher general obesity prevalence, compared to Brazilians

Abstract 1316: Preclinical Atherosclerosis in Primary Antiphospholipid Syndrome: The Impact of Oxidative Properties of High Density Lipopoprotein

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Marietta Charakida ◽  
Julian Halcox ◽  
Joanna Batuca ◽  
Ann Donald ◽  
Shirish Sangle ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Arterial Stiffness ◽  
Systolic Blood Pressure ◽  
Cardiovascular Risk Factors ◽  
Antiphospholipid Syndrome ◽  
High Density ◽  
Primary Antiphospholipid Syndrome ◽  
The Impact

Background: Antiphospholipid syndrome (APS) is characterised by increased thrombogenicity and/or pregnancy morbidity in the presence of raised levels of antiphospholipid antibodies (aPL). Increased oxidative properties of high density lipoprotein (HDL)(decreased activity of paraoxonase (PON)) is associated with increased risk for atherosclerosis and has been described in APS. The impact of PON on atherosclerotic disease progression in APS is unclear. We therefore examined the effect of PON on intima media thickness (IMT), and pulse wave velocity (PWV) in patients with positive aPL. Methods: We studied 77 women with positive aPL (aPL) aged 46.6±1.2 yrs (mean±SE) and a control group of 77 women aged 47.5±1.2 yrs matched for traditional cardiovascular risk factors. High resolution ultrasound was used to determine carotid IMT. Arterial stiffness was assessed non-invasively by carotid-radial PWV. PON activity was assessed by measuring p-nitrophenol formation and activity expressed as nmoles p-nitrophenol/ml serum/minute. Results: APL patients had significantly increased IMT and PWV compared to controls (0.75±0.02mm vs 0.65±0.01mm, p<0.001 and 9.14±0.18 m/s vs 8.56±0.21m/s, p<0.05 respectively). PON activity was significantly reduced in aPL compared to controls (91.5[64.3, 05.1]mmol/ml/min, median[IQR] vs 103.1[80.4, 111.5] mmol/ml/min, p<0.006). Although PON activity was not associated with vascular measures in controls, an inverse association was noted in aPL patients (r=−0.26 [cIMT] and r=−0.23 [PWV], both p<0.05). In multivariate analysis, accounting for cardiovascular risk factors, PON activity (β=−0.42, p<0.001), age (β=0.33, p<0.001) and systolic blood pressure (β=0.24, p<0.05) were independent determinants of cIMT while PON activity (β=−0.32, p<0.01) and systolic blood pressure (β=0.28, p<0.05) remained the only independent predictors of PWV in aPL positive patients. Conclusions: APS is associated with increased arterial stiffness and carotid intimal thickening. Paraoxonase activity is inversely associated with IMT and PWV in ApL positve patients. These findings indicate that oxidative stress may play an important role in the development of atherosclerosis in patients with primary antiphospholipid syndrome.

scholarly journals Interrelation of cardiovascular risk factors with high albuminury among patients with arterial hypertension living in Mountain Shoriya

2019 ◽  
Vol 91 (1) ◽  
pp. 71-77
Author(s):  
T A Mulerova ◽  
E S Filimonov ◽  
S A Maksimov ◽  
V N Maksimov ◽  
M I Voevoda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Arterial Hypertension ◽  
Cardiovascular Risk Factors ◽  
Abdominal Obesity ◽  
Clinical Laboratory ◽  
Medical Society ◽  
High Density Lipoproteins ◽  
Russian Society ◽  
Lipid Metabolism Disorders

Aim: to evaluate the association of a complex of cardiovascular risk factors and genetic markers with the development of high albuminuria among patients with arterial hypertension in the population of Mountain Shoriya, taking into account ethnicity. Materials and methods. A clinical epidemiological study of a compactly residing population in remote areas of Mountain Shoria was carried out. 1409 people were examined [901 people - representatives of the indigenous nationality (Shorians), 508 people - representatives of non-indigenous nationality (90% of them are Caucasians)]. Hypertension was diagnosed according to the National Guidelines of the Russian Society of Cardiology/the Russian Medical Society on Arterial Hypertension (2010). All patients underwent clinical, laboratory and instrumental investigation. To study the state of the kidneys, the concentration (the presence of elevated levels) of albumin (albuminuria) in the morning portion of urine by an immunoturbidimetric method was analyzed. Polymorphisms of genes ACE (I/D, rs4340), АGT (c.803T>C, rs699), AGTR1 (А1166С, rs5186), ADRB1 (с.145A>G, Ser49Gly, rs1801252), ADRA2B (I/D, rs28365031), MTHFR (c.677С>Т, Ala222Val, rs1801133) and NOS3 (VNTR, 4b/4a) were tested using PCR. Results. In the group of shors with arterial hypertension, high albuminuria was associated with polymorphisms of the ACE genes (OR=2.05), ADRA2B (OR=6.00), elevated triglyceride level (OR=2.86), decreased index of cholesterol of high density lipoproteins (OR=5.57) and increased index of low density lipoproteins (OR=2.49); in the new population - with polymorphisms of the AGTR1 genes (OR=8.66), ADRA2B (OR=6.53), MTHFR (OR=7.16), obesity (OR=2.72), and abdominal obesity (OR=3.14). Conclusion. The primary predictors determining the development of high albuminuria among patients with arterial hypertension in both ethnic groups were genetic ones. In addition to them, non-genetic risk factors also contributed to the development of this organ damage to the kidneys: age and lipid metabolism disorders in representatives of indigenous nationality; age and abdominal obesity in the examined patients non-indigenous nationality.

CARDIOVASCULAR RISK FACTORS PECULIARITIES IN MEN UNDER 50 YEARS OLD WITH MYOCARDIAL INFARCTION, COMPLICATED CARDIOGENIC SHOCK

2021 ◽  
pp. 234-240
Author(s):  
Gordienko A.V. ◽  
Balabanov A.S. ◽  
Biyaliev E.K.
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiovascular Risk ◽  
Cardiogenic Shock ◽  
Cardiovascular Risk Factors ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Study Group ◽  
Type I ◽  
Low Density

Relevance. Mortality in cardiogenic shock remains high. Aim. To evaluate the structure of cardiovascular risk factors features in men under 50 years old with myocardial infarction complicated by cardiogenic shock, in order to improve the prevention of this complication. Material and methods. The study included men 19-50 years old with type I myocardial infarction. The patients were divided into two age-comparable groups: I - the study group, with cardiogenic shock - seven patients; II - control, without it - 202 patients. A comparative analysis of the of cardiovascular risk factors structure in the selected groups and a risk analysis (ANOVA) of the development of cardiogenic shock were performed. Results. In the study group, the predominance of renal dysfunction (100 and 10.3%, respectively; p=0.004), alcohol abuse (71.4 and 35.2%; p=0.049), the presence of atrial fibrillation (57.1 and 5,0%; p˂0.0001), urolithiasis 28.6 and 6.4%; p=0.001), cholelithiasis 14.3 and 5.5%; p=0.001 and gout 14.3 and 0.5%; p=0.001) in history. In the control group, a history of unstable angina pectoris was more often recorded (0 and 38.1%; p=0.04). When assessing the risks, in addition to those listed, smoking 20 cigarettes per day, a decrease in lipid metabolism indicators (very low density lipoproteins 0.36 mmol/l, low density 2.7 mmol/l, cholesterol˂3,8 mmol/l, triglycerides 1.2 mmol/l, cholesterol/high density lipoproteins˂4.63), creatinine≥140 μmol/l in combination with overweight (≥96.0 kg and Quetelet index ≥31,0 kg/m2) and age (≥48 years). Conclusions. The listed factors can be used in the formation of high-risk groups for observation and timely implementation of the necessary treatment as well as for prognostic modeling of cardiogenic shock.

scholarly journals Effects of 12 Weeks of Resistance Training on Cardiovascular Risk Factors in School Adolescents

Medicina ◽  
2020 ◽  
Vol 56 (5) ◽  
pp. 220
Author(s):  
Lorrany da Rosa Santos ◽  
Silvan Silva de Araujo ◽  
Erlânyo Francisco dos Santos Vieira ◽  
Charles dos Santos Estevam ◽  
Jymmys Lopes dos Santos ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Resistance Training ◽  
Cardiovascular Risk Factors ◽  
Training Program ◽  
The Body ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Resistance Training Program ◽  
Se Brazil

Background and objectives: The practice of physical exercise, especially resistance exercise, is important for the treatment and/or prevention of cardiovascular risk factors in adult individuals. However, there are few studies on its effects on adolescent individuals. Therefore, the aim of the present study was to evaluate the effects of applying a 12-week resistance training program on cardiovascular risk factors in adolescents. Materials and Methods: Thus, 122 adolescents aged 13–16 years of both genders participated in the study from school in the city of Lagarto, Sergipe (SE), Brazil, divided into two groups: Control Group (CG) and Group undergoing resistance training (RTG). Blood collection and anthropometric measurements were performed before and after the 12-week resistance training program (RTP). Results: After 12 weeks of the RTP in the adolescents, there was a reduction in the triglyceride variables (9.55%, p = 0.0286), Low-Density Lipoproteins (LDL) (5.42%, p = 0.0244), non-High-Density Lipoproteins (HDL) (5.40%, p = 0.0019), blood glucose (6.71%, p = 0.0040), systolic blood pressure (10.13%, p < 0.0001), as well as an increase in the body weight variable (1.73%, p = 0.0003). Conclusions: It was concluded that a 12-week RTP can prevent and/or alleviate the development of several chronic degenerative diseases in adulthood and that resistance training is important for maintaining the health of adolescents.

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