Treatment with adapalene-benzoyl peroxide improve quality of life in patients with severe acne vulgaris

2013 ◽  
Vol 68 (4) ◽  
pp. AB19
2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Mohammad Sarwar Mir

Background: It is well-known that acne vulgaris is a common malady of adolescence and is easily recognized Objective: To evaluate the level of impact among acne patients on their quality of life. Methods: A total of 200 patients studied. Acne severity was graded using Global Acne Grading System (GAGS) after the clinical diagnosis. All the patients went through self-administered questionnaire of Cardiff Acne Disability Index (CADI) to fill out, to assess the reflection of patients’ experiences and perceptions. Result: Out of 200 patients, 114(57.0%) were females and 86(43.0%) were males. The maximum number of patients was in the age group of 16-20 years (142/200, 71%). Out of total 86 males, 50 (58.3%) had moderate to severe acne, whereas 62(54.38%) females had such a severe acne. 50.87% (58/114) of females had high CADI scores in comparison to only 27.9(24/86) of males. The impact on quality of life was more in the age-group of 21-30 years even though in this age group clinical severity of acne was mild to moderate only. Conclusion: Study found that individuals with acne had profound emotional, as well as, social impact on their quality of life.


2012 ◽  
Vol 87 (6) ◽  
pp. 862-869 ◽  
Author(s):  
Eleni Tasoula ◽  
Stamatis Gregoriou ◽  
John Chalikias ◽  
Dimitris Lazarou ◽  
Ifigenia Danopoulou ◽  
...  

BACKGROUND: Acne vulgaris can severely affect social and psychological functioning. OBJECTIVE: The aim of this study was to investigate the impact of acne vulgaris and its severity on Quality of Life of young adolescents in Greece. METHODS: We conducted a questionnaire based survey among 1560 adolescent between the ages of 11 and 19 years old and 1531 of these were completed. Adolescents with acne filled all the questions including the Children Dermatology Life Quality Index. Adolescents without acne filled the questions about age, family history of acne, stress and smoking. Data were analyzed with Pearson Chi Square test. RESULTS: Acne prevalence was 51.2% affecting both sexes equally. Self reported mild acne was present in 71.2% and moderate-severe acne in 28.8% of the study population. The mean age of the study population was 15.77y. The median score of Children Dermatology Life Quality Index was 4.02. The impact of acne on quality of life is associated with the severity of the acne (p<0.0001). Patients with moderate/severe acne experience greater psychosocial and emotional impairment (p<0.0001). Body image is modified proportionally to the severity of acne (p<0.0001). Symptoms and treatment of acne are factors that also influence their quality of life. Girls and boys are equally affected. Stress and heredity are correlated with acne and its severity (p<0.0001). We didn't find any correlation between smoking and acne. CONCLUSION: Acne affects Quality of Life of young adolescents in Greece. The impact is proportional to the severity of acne. More severe acne is associated with greater effect on quality of life with implications for self esteem, body image and relationships with others.


Author(s):  
Mohamad Ebrahimzadeh Ardakani ◽  
Farideh Dehghani ◽  
Narges Ghanei ◽  
Fatemeh Hoseini Kasnavie ◽  
Fariba Sepehri ◽  
...  

Background: Acne vulgaris is a common skin disease that can affect people in any ages. The development of acne have adverse effects on life quality. Psychological disorders increased in these patients and their psycho social activities have been affected. Since few studies have been done regarding illness perception in people with acne in Iran, this study aimed to investigate the association of perception of acne disease and quality of life in central of IranMethods: we analyzed 200 patients Acne Vulgaris referred to Khatam-Al Anbia in 2013-14 by questionnaire of perception of disease (Brief IPQ) and quality of life (DLQL. the data was analyzed using t-test and Chi-square by SPSS-16Results: Mean age of patients was 24.3 years and 158 people (79%) were women and 42 people (21 %) were men. Mean quality life score in women was 8.79±5.3 and in men was 8.69±5.18. Most patients had moderate acne and duration of their disease was between 1 to 5 years. 136 people were 18 to 25 years old and 64 persons were higher than 25 years. The mean perception scores in men and women were 51.83 and 53.26 respectively In this study, there was a relation between sex (P=0.03), Acne severity and duration with quality of life score.Conclusion: Women and patients with severe acne and longer duration of symptoms had higher quality life score that had more disorder in life.. There was relation between perception and sex and duration of symptoms.


2020 ◽  
Vol 21 (6) ◽  
pp. 891-899
Author(s):  
Stephen K. Tyring ◽  
Leon Kircik ◽  
David M. Pariser ◽  
Heather C. Woolery-Lloyd ◽  
Julie C. Harper ◽  
...  

2021 ◽  
Vol 19 (2) ◽  
Author(s):  
Ghadah Mohammad Alasbi ◽  
Fatima Riaz ◽  
Halimah Nasser Kidwan ◽  
Zanah Abdullah Zanah Abdullah ◽  
Tabinda Ashfaq ◽  
...  

Objective: To know the impact of acne among female university students on their quality of life. Methodology: A cross sectional study conducted included 260 female students at the King Khalid University. A self-administered questionnaire was used in Arabic for data collection. It consisted of personal data, practices and conditions related to health, specific questions on acne vulgaris and the Acne Quality of Life (QOL) questionnaire. Results: Prevalence of acne among participant students was 87%. Its severity among 48% of participants was mild, 39.6% was moderate, while 12.3% had severe acne. Its prevalence did not differ significantly according to participants’ personal characteristics. The mean score for self-perception was 18.4+8.0, for role emotional was 14.4+8.8, for role social was 14.4+6.4, for acne symptoms was 13.4+5.2, while mean overall score was 60.5+24.4. Acne QOL scores for all domains were significantly lower among students who have acne. Scores for all domains and overall scores were lowest among students having severe acne. Students’ acne QOL scores differed significantly according to their family monthly income regarding “self-perception” (p=0.005), role emotional (p=0.037) and overall (p=0.012). Conclusions: Prevalence of facial acne is very high among students and significantly affects their QOL. During management of acne patients, health care professionals should consider its psychosocial aspect. Limitations: Generalizability of the results is limited to female university students only and limited personal characteristics were assessed in the present study. Conflict of interest: There is no conflict of interest involved with this study Key words: Acne, quality of life, female university students.


2021 ◽  
Vol 11 (9) ◽  
pp. 33-40
Author(s):  
Shabnam .

Background and Objective: Acne vulgaris is a chronic condition affecting more than 85% of adolescents and young adults. It is one of the most common diseases affecting humanity and its impact on quality of life (QoL) is important. The interaction of acne and psychosocial issues is complex and, in adolescence, can be associated with developmental issues of body image, socialization and sexuality. Thus, the present study was conducted to assess the prevalence of acne vulgaris, its impact on quality of life and to study socio-demographic factors, family history and lifestyle among the selected schools in Jalahalli area of Bengaluru. Methods: The present study was descriptive cross sectional school based study conducted in the Jallahalli area of Bengaluru city from January 2017 to December 2017. A total of 200 subjects were included. A predesigned, pretested, structured questionnaire consisting of questions on various aspects regarding socio-demographic profile, assessment of quality of life and symptoms of acne vulgaris were administered to the participants fulfilling inclusion criteria. Data regarding the severity of acne vulgaris and Quality of life status were obtained by using Global Acne Grading System and CADI and CDLQI/DLQI respectively. SPSS 18.0 software was used for data analysis. Results: Findings of the study revealed that, Acne prevalence was 87% affecting both sexes. Self reported mild acne was present in 85.1% and moderate severe acne in 14.9% of the adolescents. The mean age of the subjects was 14.78 years. 52.5% were females and 47.5% were males. A strong relation was found between the severity of acne and quality of life (p<0.001).Subject with moderate/severe acne experience greater impairment in quality of life (p<0.001). Heredity is correlated with acne and its severity was significant. Interpretation and Conclusion: Acne affects the quality of life of an adolescent. The impact is proportional to the severity of acne. More severe acne is associated with greater effect on quality of life. The present study reveals that increasing prevalence of Acne vulgaris and poor quality of life among the adolescents. Evaluation of quality of life in such patients may greatly help in the better management of acne, hence improving their quality of life. Key words: Acne vulgaris; Adolescent; Quality of life; GAGS; CDLQI/DLQI.


2021 ◽  
Vol 37 (3) ◽  
Author(s):  
Shaheen Naveed ◽  
Sadia Masood ◽  
Atiya Rahman ◽  
Safia Awan ◽  
Saadia Tabassum

Objectives: The current study aimed to determine the effect of acne vulgaris on quality of life of young adults and to assess the correlation between acne severity and impairment of quality of life (QOLI). Methods: In this multi-center cross-sectional study, 163 young adults with acne vulgaris were assessed for severity and quality of life impairment between December 2016 and May 2017 at three tertiary care hospitals. Cardiff Acne Disability Index (CADI) was used to assess the quality of life while the severity of acne measured by Global Acne Grading System (GAGS). Data were collected on standardized forms, with CADI, GAGS scores, and sociodemographic data and analyzed using SPSS version 9. The quantitative variables were presented as means, median and qualitative variables expressed as frequency and percentages. P-value ≤0.05 was considered as statistically significant.  Results: Out of 163 patients enrolled in this study, the mean age was 21.6 ± 4.9 years and 124 were females and 39 males. In mild QOLI, 56 (87.5%) cases were affected with mild, 11 (13.4%) with moderate and 1 (1.5%) case had severe acne. While, in moderate QOLI, 8(12.5%) cases were of mild, 60 (73.2%) were moderate and 6 (35.3%) cases affected with severe acne. The severe impairment of QOL noted in 11 (13.4%) moderate and 10 (58.8%) severe acne cases. The relationship between sex was statistically significant, (P<0.001). The result showed significant correlation between severity of acne vulgaris and the quality of life impairment of these patients (P<0.001). Conclusion: This study showed significant correlation between acne vulgaris and quality of life impairment. Cardiff acne disability index has proven to be a reliable tool to assess the quality of life. It is recommended to be used routinely in dermatology clinics to provide tailored treatment to individuals because mild disease may be disproportionately distressing for patients. doi: https://doi.org/10.12669/pjms.37.3.2819 How to cite this:Naveed S, Masood S, Rahman A, Awan S, Tabassum S. Impact of acne on quality of life in young Pakistani adults and its relationship with severity: A multicenter study. Pak J Med Sci. 2021;37(3):---------. doi: https://doi.org/10.12669/pjms.37.3.2819 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Dermatology ◽  
2019 ◽  
Vol 235 (6) ◽  
pp. 463-470 ◽  
Author(s):  
Marianna Donnarumma ◽  
Davide Fattore ◽  
Vincenzo Greco ◽  
Maria Ferrillo ◽  
Maria Vastarella ◽  
...  

Introduction: Acne is a common skin disease with important psychosocial impact. Often inadequate compliance affects the efficacy of the therapy. Because of emerging use of mobile and electronic health technology, the recent literature evaluated the helpfulness of the tools in medication adherence. The first goal of our study was to evaluate the adherence to therapy with topical adapalene 0.3%/benzoyl peroxide (A-BPO) 2.5% in different groups of patients who received explicative information supported by different strategies. The second goal was to evaluate the patient’s quality of life and skin parameters. Materials and Methods: We enrolled 126 subjects with mild to severe acne vulgaris. They were randomized into 3 groups of 42 patients each and applied daily topical A-BPO (0.3%, 2.5%) for 12 weeks. The first group (G1) was trained on the gel application by an explicative leaflet. The second group (G2) received the same instructions as group 1 and a daily SMS to remind them of the application of the product. The third group (G3) only received standard instructions. Evaluations were performed at the beginning of treatment (T0) and after 12 weeks (T1): assessment of acne severity using the Investigator’s Global Assessment (IGA) Scale for Acne Severity, quality of life by the Cardiff Acne Disability Index (CADI) and the Patient-Doctor Relationship Depth-of-Relationship Scale (PDRDS), skin pH, grade of hydration and adherence to treatment with a 7-day recall calendar were also measured. Results: After 12 weeks of therapy, we observed a reduction in IGA in all groups confirming the clinical efficacy of the product. In the multiple comparison analysis of IGA score reduction, a significant difference was found in G2 versus G1 and G2 versus G3, while the G1 versus G3 comparison was not statistically significant. However, the leaflet group (G1) showed better results compared to the no-leaflet group (G3). Supporting these data, we observed that adherence days correlated positively with the improvement of the single parameters. Moreover, we observed that SMS and leaflet groups had a greater improvement in quality of life evaluated by CADI and PDRDS scores. Conclusions: According to our data, this experimental setup based on text message service and leaflet service is inexpensive and easy to use. Physicians could consider using these items in their practice to enhance patient adherence and satisfaction as well as treatment outcome.


2021 ◽  
pp. 11-15
Author(s):  
N. V. Gryazeva ◽  
A. V. Tamrazova

Acne vulgaris is a common disease affecting up to 85 % of adolescents. Localization of dermatosis in cosmetically signifiant areas, the duration of the therapy and the formation of post-acne symptoms have a high psycho-emotional load and negatively affect the quality of life. Due to the fact that acne affects the most vulnerable and socially sensitive age group, it is imperative not to overlook psychological abnormalities such as anxiety, depression and suicidal thoughts. This review presents the types of diagnostic scales for assessing the quality of life of patients with acne, pathogenesis and risk factors for scar formation – the main factor affecting the self-esteem of patients with acne vulgaris, and also proposed new methods of combination therapy with the use of corticosteroids and isotretinoin in the treatment of severe forms.


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