GW27-e0345 The retrospective analysis of clinical characteristics and risk factors in elderly patients that complicated with pneumonia after ischemic stroke

ABSTRACT Background: Posterior circulation stroke (PCS), though less common, differs from stroke in anterior circulation in many aspects. Relatively, it portends a poorer prognosis. However, there is a paucity of data from African countries, in particular, where stroke is a menace. Objective: The study aimed to evaluate the etiology, clinical characteristics, outcome, and predictors of outcome in a cohort of patients with IPCS in Northwestern Nigeria. Materials and Methods: Out of 595 patients with stroke, we prospectively analyzed 57 patients with PCS in a Tertiary Care Center in Kano, Northwestern Nigeria. Patients were analyzed for demographic data, risk factors, clinical characteristics, stroke subtypes, mortality, and predictors of mortality. Results: Posterior circulation ischemic stroke accounted for 57 (9.6%) of 595 of all strokes seen in the study period. They comprised 44 males (mean age 47.8 ± 17.7) and 13 females (mean age 46.3 ± 13.7). Overall, their age ranged between 24 and 90 (mean age 47.4 ± 16.7). However, 52.7% of the patients were < 45 years of age. The most common site affected was the cerebellum seen in 33 (57.9%) patients. Hypertension was the most common risk factor (86%). Headache and vertigo were the most common features accounting for 83.6% and 86.3%, respectively. Thirty-eight (66.7%) patients had an ischemic stroke. Twenty-one (36.8%) of the patients died during the 1-month period of follow-up. Independent predictors of death in the study were hyperglycemia on admission and hemorrhagic stroke. Conclusions: IPCS occurred in a relatively younger age group. Headache and vertigo were the most common symptoms. The independent predictors of death in the study were hyperglycemia at presentation and hemorrhagic stroke.

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Abstract 140: Association Between Epilepsy and the Risk of Ischemic Stroke or Myocardial Infarction

Stroke ◽

10.1161/str.48.suppl_1.140 ◽

2017 ◽

Vol 48 (suppl_1) ◽

Author(s):

Matthew A Mercuri ◽

Alexander E Merkler ◽

Neal S Parikh ◽

Michael E Reznik ◽

Hooman Kamel

Keyword(s):

Risk Factors ◽

Myocardial Infarction ◽

Ischemic Stroke ◽

Elderly Patients ◽

Proportional Hazards ◽

Predictor Variable ◽

Cox Proportional Hazards ◽

Vascular Events ◽

Increased Risk ◽

Acute Mi

Background: Vascular brain injury can result in epilepsy. It is posited that seizures in elderly patients might reflect subclinical vascular disease and thus herald future clinical vascular events. Hypothesis: Seizures in elderly patients are associated with an increased risk of ischemic stroke or myocardial infarction (MI). Methods: We obtained inpatient and outpatient claims data from 2008-2014 on a 5% sample of Medicare beneficiaries ≥66 years of age. The predictor variable was epilepsy, defined as two or more inpatient or outpatient claims with a diagnosis of seizure. The primary outcome was a composite of ischemic stroke or acute MI. The predictors and outcomes were all ascertained with previously validated ICD-9-CM code algorithms. Survival statistics and Cox proportional hazards models were used to assess the relationship between epilepsy and incident ischemic stroke or MI while adjusting for demographic characteristics and vascular risk factors. Patients were censored at the first occurrence of a stroke or MI, at the time of death, or on December 31, 2014. Results: Among 1,548,556 beneficiaries with a mean follow-up of 4.4 (±1.8) years, 15,055 (1.0%) developed epilepsy and 121,866 (7.9%) experienced an ischemic stroke or acute MI. Patients with seizures were older (76.1 versus 73.7 years) and had a significantly higher burden of vascular comorbidities than the remainder of the cohort. The annual incidence of stroke or acute MI was 3.28% (95% confidence interval [CI], 3.10-3.47%) in those with seizures versus 1.79% (95% CI, 1.78-1.80%) in those without (unadjusted hazard ratio [HR], 1.89; 95% CI, 1.78-2.00). After adjustment for demographics and risk factors, epilepsy had a weak association with the composite outcome (adjusted HR, 1.36; 95% CI, 1.29-1.44), a stronger association with ischemic stroke (adjusted HR, 1.77; 95% CI, 1.65-1.90), and no association with acute MI (adjusted HR, 0.95; 95% CI, 0.86-1.04). Conclusions: We found an association between epilepsy in elderly patients and future ischemic stroke but not acute MI. Therefore, seizures might signify occult cerebrovascular disease but not necessarily occult disease in other vascular beds.

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Gender differences in stroke subtypes, severity, risk factors, and outcomes among elderly patients with acute ischemic stroke in Uzbekistan

Journal of the Neurological Sciences ◽

10.1016/j.jns.2017.08.3279 ◽

2017 ◽

Vol 381 ◽

pp. 377

Author(s):

N. Tolibova ◽

N. Vakhabova

Keyword(s):

Risk Factors ◽

Gender Differences ◽

Ischemic Stroke ◽

Elderly Patients ◽

Acute Ischemic Stroke ◽

Stroke Subtypes

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Intraoperative Hypotension and Related Risk Factors for Postoperative Mortality After Noncardiac Surgery in Elderly Patients: A Retrospective Analysis Report

Clinical Interventions in Aging ◽

10.2147/cia.s327311 ◽

2021 ◽

Vol Volume 16 ◽

pp. 1757-1767

Author(s):

Benhui Zhao ◽

Xingtong Chen ◽

Qian Chen ◽

Gaoming Li ◽

Zhe Chen ◽

...

Keyword(s):

Risk Factors ◽

Elderly Patients ◽

Retrospective Analysis ◽

Postoperative Mortality ◽

Noncardiac Surgery ◽

Intraoperative Hypotension ◽

Related Risk ◽

Surgery In Elderly

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Assessment of risk factors and clinical characteristics of elderly patients with hypertensive encephalopathy against the background of hypertension

East European Journal of Neurology ◽

10.33444/2411-5797.2015.5(5).35-39 ◽

2015 ◽

pp. 35-39

Author(s):

V. V. Jaworski

Keyword(s):

Risk Factors ◽

Elderly Patients ◽

Cerebrovascular Disease ◽

Detailed Analysis ◽

Neurological Examination ◽

Cognitive Functions ◽

Clinical Characteristics ◽

Basic Research ◽

Hypertensive Encephalopathy ◽

Middle Aged

The article presents the results of clinical and neurological examination of 105 elderly and middle- aged hipertenzivnoyu encephalopathy of II degree on a background of hypertension. The urgency of a detailed analysis of the patients to determine risk factors for cerebrovascular disease and basic research cognitive functions of patients.

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The Epidemiological, Risk Factors and Clinical Characteristics of Ischemic Stroke in Ardabil Province, Iran: a Hospital Based Study

Journal of Biostatistics and Epidemiology ◽

10.18502/jbe.v6i1.4759 ◽

2020 ◽

Author(s):

Ghasem Fattahzadeh-Ardalani ◽

Afshan Sharghi ◽

Abolfazl Atalu ◽

Farzad Noori

Keyword(s):

Risk Factors ◽

Ischemic Stroke ◽

Urban Areas ◽

Clinical Characteristics ◽

Heart Diseases ◽

Cross Sectional Study ◽

P Value ◽

City Hospital ◽

Cross Sectional ◽

Epidemiological Risk

Introduction: Stroke is the third most common cause of death in world after heart diseases and cancer. Due to the higher rate of stroke and less attention to its occurrence, assessing the prevalence of ischemic brain stroke and its clinical patterns across countries and nations such as Iran could be valuable and important. Objectives: The aim of this study was to assess the epidemiological, Risk factor and clinical characteristics of ischemic stroke in Ardabil province. Materials and Methods: This descriptive cross-sectional study has been done on 676 patients with ischemic stroke who referred to Ardabil city hospital during at year 2018. Data collected by using a checklist including demographic and clinical data of patients. Collected data were analyzed by statistical methods in SPSS version 21. The p-value less than 0.05 was considered as significant. Results: Of all patients, 294 (43.5%) were female and rest of them were male. The mean age of patients was 69.3±13.2 years. Of all patients, 25.3% arrived to the hospital in less than 4.5 hours. The difference between arrival time to the hospital in rural and urban patients was significant. The most risk factors were seen in both sexes was HTN and in female only was DM and in male only was CVA. The results of CT and MRI showed that 30% and 64.9% of patients had lesion respectively that of them the most lesion in MRI was SMALL VESSEL and in CT was Middle Cerebral Artery (MCA). Conclusion: Results showed that the patients who live in urban areas arrive to emergency sooner than rural patients. The significant relation was seen between AF, residence place and valvular with arriving time to hospital.

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