scholarly journals Assessment of risk factors and clinical characteristics of elderly patients with hypertensive encephalopathy against the background of hypertension

2015 ◽  
pp. 35-39
Author(s):  
V. V. Jaworski
Keyword(s):  
Risk Factors ◽  
Elderly Patients ◽  
Cerebrovascular Disease ◽  
Detailed Analysis ◽  
Neurological Examination ◽  
Cognitive Functions ◽  
Clinical Characteristics ◽  
Basic Research ◽  
Hypertensive Encephalopathy ◽  
Middle Aged

The article presents the results of clinical and neurological examination of 105 elderly and middle- aged hipertenzivnoyu encephalopathy of II degree on a background of hypertension. The urgency of a detailed analysis of the patients to determine risk factors for cerebrovascular disease and basic research cognitive functions of patients.

scholarly journals HsCRP Variation is the Main Risk Factor for Clinical Outcome in COVID-19 Hospitalized Young and Middle-Aged Patients

2020 ◽  
Author(s):  
Zhelong Liu ◽  
Danning Wu ◽  
Xia Han ◽  
Wangyan Jiang ◽  
Lin Qiu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Elderly Patients ◽  
Clinical Characteristics ◽  
The Elderly ◽  
Middle Aged ◽  
Aged Patients ◽  
Icu Admission ◽  
Discharged Patients ◽  
Independent Risk Factors

Abstract Background: The clinical characteristics and risk factors of clinical outcomes of COVID-19 in elderly and non-elderly patients show great difference. We are the first to explore the relationship between hsCRP variation and intensive care unit (ICU) admission in young and middle-aged COVID-19 patients compared with elderly patients.Methods: We included 273 hospitalized patients with confirmed COVID-19 from Tongji Hospital, Wuhan, China from Feb 10, 2020 to Mar 8, 2020. Clinical characteristics and risk factors of outcomes were compared between young and middle-aged patients with elderly patients.Results: Among young and middle-aged patients, hsCRP variation in those admitted to ICU was significantly higher than that in discharged patients. Among patients admitted to ICU, hsCRP variation showed significantly difference between young and middle-aged patients and elderly patients (median, 67.9 vs -10.2, P < 0.01). The hsCRP variation was an independent risk factor for ICU admission in young and middle-aged patients (OR = 1.068) and ROC curve revealed hsCRP variation significant for the prediction of ICU admission (AUC = 0.925) with 92.9% sensitivity and 95.5% specificity. Conclusion: HsCRP variation is the major independent risk factors for ICU admission in young and middle-aged COVID-19 inpatients, but not in the elderly patients.

scholarly journals Herb-Induced Liver Injury Related to Reynoutria multiflora (Thunb.) Moldenke: Risk Factors, Molecular and Mechanistic Specifics

2021 ◽  
Vol 12 ◽  
Author(s):  
Xing-Ran Zhai ◽  
Zheng-Sheng Zou ◽  
Jia-Bo Wang ◽  
Xiao-He Xiao
Keyword(s):  
Risk Factors ◽  
Herbal Medicine ◽  
Liver Injury ◽  
Clinical Characteristics ◽  
Molecular Mechanisms ◽  
Basic Research ◽  
Polygonum Multiflorum ◽  
The West ◽  
The World ◽  
Molecular Aspects

Herbal medicine is widely used in Asia as well as the west. Hepatotoxicity is one of the most severe side effects of herbal medicine which is an increasing concern around the world. Reynoutria multiflora (Thunb.) Moldenke (Polygonum multiflorum Thunb., PM) is the most common herb that can cause herb-induced liver injury (HILI). The recent scientific and technological advancements in clinical and basic research are paving the way for a better understanding of the molecular aspects of PM-related HILI (PM-HILI). This review provides an updated overview of the clinical characteristics, predisposing factors, hepatotoxic components, and molecular mechanisms of PM-HILI. It can also aid in a better understanding of HILI and help in further research on the same.

scholarly journals Prevalence and Related Risk Factors Associated with Coronary Heart Disease (CHD) Among Middle Aged and Elderly Patients with Vision Impairment (VI)

2021 ◽  
Author(s):  
Shengmei Qin ◽  
Hengjing Wu ◽  
Hao Wang ◽  
Qi Li ◽  
Jie Zhou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Elderly Patients ◽  
Weight Management ◽  
Visually Impaired ◽  
Vision Impairment ◽  
Middle Aged ◽  
Factors Associated ◽  
Related Risk

Abstract Objective: To investigate the prevalence and related risk factors associated with coronary heart disease（CHD） among middle aged and elderly patients with vision impairment (VI). Study design: cross-sectional research. Methods: The study was conducted with 1,355 visually impaired adults over 45 years old, recruited from a Rehabilitation Hospital in China. Visual impairment is diagnosed by a doctor according to guidelines. Data was analyzed using multiple correspondence and logistic regression analysis. This research represents an important step towards the development of empirically based practical suggestions for decision-makers and health professionals that support visually impaired middle-aged and elderly people to participate in physical exercise and weight management when needed. Results: Of the 1335 middle aged and elderly adults with VI, a total of 154 (11.5%) developed CHD. Statistical analysis based on age grouping indicated that hypertension, diabetes, blindness, gentle and moderate activity were shown to have a strong association with development of CHD. In addition, fasting plasma glucose, heart rate (<60), and BMI were important risk factors for CHD in the middle-aged group and the elderly group respectively.Conclusion: Suggestions for related policy changes should focus on the social and environmental aspects. This includes developing a more accessible and inclusive environments and providing meaningful information about physical activity and weight management to middle-aged and elderly people with visually impaired.

scholarly journals Age characteristics of risk cardiovascular complications in women with left breast cancer with preserved ejection fraction at the stage of chemotherapy and radiotherapy

Kardiologiia ◽  
2019 ◽  
Vol 59 (7S) ◽  
pp. 23-30
Author(s):  
I. V. Vologdina ◽  
R. M. Zhabina
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Ejection Fraction ◽  
Elderly Patients ◽  
The Elderly ◽  
Cardiovascular Complications ◽  
Left Breast ◽  
Middle Aged ◽  
Aged Patients ◽  
Score Risk

Aim. A study of the risk factors for middle-aged and elderly women HER2neu with negative left breast cancer and a normal ejection fraction at the stage of chemoradiotherapy in everyday clinical practice. Matherial and methods. 61 women with left breast cancer without severe cardiovascular pathology were examined at the stage of doxorubicin therapy and 3D conformal radiation therapy. Group 1 comprised 32 patients of middle age (49.8 ± 4.5 years). Group 2 comprised 29 elderly patients (68.3 ± 3.6 years). In addition to Score risk assessment, additional factors, including psychosocial factors, were studied. All patients underwent ECG, echocardiography and 24-hour ECG monitoring. Anxiety levels were assessed using the HADS scale and scale CH. D. Spielberger –Yu.L. Khanin. The study was conducted before the start of treatment, after the completion of the doxorubicin course and after the completion of the course of radiotherapy. Results with discussion. In middle-aged patients, moderate Score risk was found in 21.9%, in the elderly at 58.6% (p = 0.0043, RR 2.68, 95% CI 1.301–5.520). A high Score risk was found in 15.6% of middle-aged patients and 41.4% of elderly patients (p = 0.0438, RR 2.648, 95% CI 1061–6.607). The most common risk factors in the patients studied in addition to age were heredity, overweight, hypercholesterolemia and diabetes mellitus. All examined patients had moderate reactive anxiety. Patients of middle age have moderate personal anxiety, in elderly patients high personal anxiety. After treatment with doxorubicin in a cumulative dose not exceeding 360 mg/m2 , a reduction in the ejection fraction below 50% was found in 6 middle-aged patients and 17.2% in elderly patients. Asymptomatic diastolic dysfunction was detected in 31.3% of middle-aged patients and 55.2% of the elderly. In patients of both groups, after arranging treatment, arrhythmia was detected. Conclusions. The obtained data indicate to the need for in-depth examination of middle-aged and especially elderly patients with left breast cancer with an assessment of risk factors and conducting an in-depth examination using Echocardiography, 24-hour ECG monitoring and psychological testing to prevent and early detection of cardiovascular complications.

scholarly journals Influencing Factors of Hospital-Acquired Pneumonia Infection in the Middle-Aged and Elderly Patients With Schizophrenia

2021 ◽  
Vol 12 ◽  
Author(s):  
Mi Yang ◽  
Qiwen Li ◽  
Chunzhi Wang ◽  
Li Li ◽  
Min Xu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Elderly Patients ◽  
Infection Rate ◽  
Large Scale ◽  
Antipsychotic Drugs ◽  
Personal Characteristics ◽  
Middle Aged ◽  
Chi Square ◽  
Hospital Acquired Pneumonia ◽  
Hospital Acquired

Introduction: Pneumonia is an important cause of death in patients with schizophrenia. It is critical to understand the risk factors of hospital-acquired pneumonia (HAP) and determine prevention strategies to reduce HAP. The aim of this study is to elucidate the risk factors for HAP in the middle-aged and elderly hospitalized patients with schizophrenia.Methods: We retrospectively reviewed the medical records of 2,617 the middle-aged and elderly patients (age ≥ 50) with schizophrenia who were admitted for the first time to a large-scale psychiatric hospital between 2016 and 2020. The factors related to the incidence of HAP in patients were analyzed, including personal characteristics, antipsychotics, and non-antipsychotics.Results: The HAP infection rate of hospitalized the middle-aged and elderly patients with schizophrenia was 7.8%. Chi-square analyses showed that older age, male, and ≥60 days of hospitalization were risk factors for HAP infection (χ2 = 94.272, p &lt; 0.001; χ2 = 22.110, p &lt; 0.001; χ2 = 8.402, p = 0.004). Multivariate logistic regression showed that quetiapine, clozapine, and olanzapine significantly increased the incidence of HAP (OR = 1.56, 95% CI = 1.05–2.32, p = 0.029; OR = 1.81, 95% CI = 1.26–2.60, p = 0.001; OR = 1.68, 95% CI = 1.16–2.42, p = 0.006). Antipsychotic drugs combined with aceglutamide had an effect on HAP (OR = 2.19, 95% CI = 1.38–3.47, p = 0.001).Conclusion: The high HAP infection rate in hospitalized the middle-aged and elderly patients with schizophrenia may be related to the increase of age and the use of antipsychotic drugs. The types and dosages of antipsychotic drugs should be minimized while paying attention to the mental symptoms of patients.

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