P3-077: A Translational Research Strategy to Individualize Prediction of Long-Term Cognitive Trajectory

2016 ◽  
Vol 12 ◽  
pp. P847-P847
Author(s):  
Chih-Lin Chi ◽  
Wenjun Zeng ◽  
Wonsuk Oh ◽  
Soo Borson
2016 ◽  
Vol 12 ◽  
pp. P185-P186
Author(s):  
Chih-Lin Chi ◽  
Wenjun Zeng ◽  
Wonsuk Oh ◽  
Soo Borson

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Silvia Regina Campos ◽  
Adriana Gomes de Menezes

This paper aims to present a methodological approach to align the strategic plans among Institutions in the area of Higher Education. It adopts an eight-phase research framework. It is a qualitative study which adopts a deductive and exploratory research strategy through the analysis of some institution's strategic plans and other relevant documents to propose a methodological approach for the alignment. Its contribution shall enable HEIs to improve synergy which is essential for achieving efficiency, efficacy and long-term sustainability in the light of the recent challenges facing their environment, considering that the strategy execution and its implementation has been considered much more difficult and complicated to overcome. Particular it shall contribute to alignment among other HEIs which have been subject to mergers and acquisitions processes, in the recent years.


Medicina ◽  
2019 ◽  
Vol 55 (7) ◽  
pp. 337 ◽  
Author(s):  
Rondanelli ◽  
Faliva ◽  
Gasparri ◽  
Peroni ◽  
Naso ◽  
...  

Background and objective: Often micronutrient deficiencies cannot be detected when patient is already following a long-term gluten-free diet with good compliance (LTGFDWGC). The aim of this narrative review is to evaluate the most recent literature that considers blood micronutrient deficiencies in LTGFDWGC subjects, in order to prepare dietary supplementation advice (DSA). Materials and methods: A research strategy was planned on PubMed by defining the following keywords: celiac disease, vitamin B12, iron, folic acid, and vitamin D. Results: This review included 73 studies. The few studies on micronutrient circulating levels in long-term gluten-free diet (LTGFD) patients over 2 years with good compliance demonstrated that deficiency was detected in up to: 30% of subjects for vitamin B12 (DSA: 1000 mcg/day until level is normal, then 500 mcg), 40% for iron (325 mg/day), 20% for folic acid (1 mg/day for 3 months, followed by 400–800 mcg/day), 25% for vitamin D (1000 UI/day or more-based serum level or 50,000 UI/week if level is <20 ng/mL), 40% for zinc (25–40 mg/day), 3.6% of children for calcium (1000–1500 mg/day), 20% for magnesium (200–300 mg/day); no data is available in adults for magnesium. Conclusions: If integration with diet is not enough, starting with supplements may be the correct way, after evaluating the initial blood level to determine the right dosage of supplementation.


2008 ◽  
Vol 13 (1) ◽  
pp. 37-52 ◽  
Author(s):  
Robert A. Roe

Against the background of a growing awareness of time among researchers, this articles sets out to assess the current position of time in applied psychological theory and research. A critical analysis of recent publications in The Journal of Applied Psychology and Applied Psychology, An International Review reveals that with some noticeable exceptions, the role of time in human behavior is still largely neglected. It is posited that this state of affairs can be explained by a conceptual bias among researchers, which makes them think in terms of “what is” rather than “what happens.” A proposal is made for an alternative way of conceptualizing, designated as temporalism, which starts from the concept of phenomenon, which is defined dynamically and operationalized with the help of time. A plea is made for a research strategy that comprises the identification of the dynamic features of phenomena, an analysis of their temporal relations, and an assessment of long term stability and changes of temporal parameters. It is argued that such an approach leads to theoretical innovations and to a substantial expansion of possibilities for intervention. This is illustrated by a discussion of three prototypical patterns of development referred to as improvement, bifurcation, and relapse, which underlie a broad range of practical problems known from social and organizational settings. Finally, attention is directed to the role that time plays when psychological knowledge is applied to such practical problems. It is concluded that time should not only be addressed in the study of behavior of other people but also in the complex interactions between psychologists and clients involved in the application of psychology.


2006 ◽  
Vol 42 (2) ◽  
pp. 127-146 ◽  
Author(s):  
C. M. STIRLING ◽  
D. HARRIS ◽  
J. R. WITCOMBE

There is no one widely accepted method of managing international agricultural research and numerous different models exist. Here we review one in particular, referred to as the ‘institute without walls’, from the perspective of the UK Department for International Development's (DFID) Renewable Natural Resource (RNR) Research Strategy (1990–2006). We begin with a brief history of the RNR Research Strategy from 1990 to 2004. We then draw on nearly 15 years experience of managing one of the programmes within the RNR Research Strategy to assess critically the impact of externally and internally imposed organizational and management changes on the performance of the DFID Plant Sciences Programme (PSP). The current RNR Research Strategy (1995–2006), with its emphasis on demand-led research, has greatly increased the relevance and effectiveness of DFID's natural resources research. A comparison between the PSP in 2004 and the early 1990s inevitably concludes that the programme has been transformed: unlike in 1991, research is now firmly demand-driven, much is based in developing countries and farmers are benefiting from the research. Over time, the outputs of the long-term strategic research have been applied in practical plant breeding and participatory crop improvement programmes. Key to the success of the PSP has been the provision of continuous, long-term funding which has allowed projects time to develop and produce outputs of real value to end users. Alongside this, the ability of the PSP to build long-term, in-country partnerships has ensured the effective adoption of its research outputs. We conclude that the successes of the PSP have largely derived from (i) identification of research that is clearly demand driven, (ii) continuous long-term funding that has allowed research to move from the strategic to adaptive phase, (iii) continuity of management, and (iv) the flexibility to develop a wide range of partnerships, both in-country and overseas, based on their ability to deliver.


2021 ◽  
Vol 8 ◽  
Author(s):  
Alexandru Szakács

The article discusses the controversial topic of the precursor-based earthquake prediction, based on a personal perspective intending to stir the current still waters of the issue after twenty years have passed since the influential debate on earthquake prediction hosted by Nature in 1999. The article challenges the currently dominant pessimistic view on precursor-based earthquake prediction resting on the “impossible in principle” paradigm. Instead, it suggests that a concept-based innovative research strategy is the key to obtain significant results, i.e., a possible paradigm shift, in this domain. The basic concept underlying such a possible strategy is the “precursory fingerprint” of individual seismic structures derived from the uniqueness of the structures themselves. The aim is to find as many unique fingerprints as possible for different seismic structures worldwide, covering all earthquake typologies. To achieve this, a multiparameter approach involving all possible sensor types (physical, chemical, and biological) of the highest available sensitivity and artificial intelligence could be used. The findings would then be extrapolated to other similar structures. One key issue is the emplacement location of the sensor array in privileged “sensitive” Earth surface sites (such as volcanic conduits) where the signal-to-noise ratio is maximized, as suggested in the article. The strategy envisages three stages: experimental phase, validation, and implementation. It inherently could be a costly, multidisciplinary, international, and long-term (i.e., multidecade) endeavor with no guaranteed success, but less adventurous and societally more significant to the currently running and well-funded SETI Project.


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