scholarly journals Fabrication of β-carotene nanoemulsion-based delivery systems using dual-channel microfluidization: Physical and chemical stability

2017 ◽  
Vol 490 ◽  
pp. 328-335 ◽  
Author(s):  
Xiang Luo ◽  
Yanyan Zhou ◽  
Long Bai ◽  
Fuguo Liu ◽  
Yihui Deng ◽  
...  
2017 ◽  
Vol 69 ◽  
pp. 49-55 ◽  
Author(s):  
Jingjing Chen ◽  
Fang Li ◽  
Zhengze Li ◽  
David Julian McClements ◽  
Hang Xiao

2018 ◽  
Vol 242 ◽  
pp. 395-403 ◽  
Author(s):  
Fabienne Weigel ◽  
Jochen Weiss ◽  
Eric Andrew Decker ◽  
David Julian McClements

2019 ◽  
Vol 121 ◽  
pp. 229-237 ◽  
Author(s):  
Carina M. Borba ◽  
Millene N. Tavares ◽  
Luana P. Macedo ◽  
Gabriela S. Araújo ◽  
Eliana B. Furlong ◽  
...  

2016 ◽  
Vol 196 ◽  
pp. 821-827 ◽  
Author(s):  
Gabriel Davidov-Pardo ◽  
Cansu Ekin Gumus ◽  
David Julian McClements

Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 426
Author(s):  
Vaibhav Kumar Maurya ◽  
Amita Shakya ◽  
Manjeet Aggarwal ◽  
Kodiveri Muthukaliannan Gothandam ◽  
Torsten Bohn ◽  
...  

Nanotechnology has opened new opportunities for delivering bioactive agents. Their physiochemical characteristics, i.e., small size, high surface area, unique composition, biocompatibility and biodegradability, make these nanomaterials an attractive tool for β-carotene delivery. Delivering β-carotene through nanoparticles does not only improve its bioavailability/bioaccumulation in target tissues, but also lessens its sensitivity against environmental factors during processing. Regardless of these benefits, nanocarriers have some limitations, such as variations in sensory quality, modification of the food matrix, increasing costs, as well as limited consumer acceptance and regulatory challenges. This research area has rapidly evolved, with a plethora of innovative nanoengineered materials now being in use, including micelles, nano/microemulsions, liposomes, niosomes, solidlipid nanoparticles, nanostructured lipids and nanostructured carriers. These nanodelivery systems make conventional delivery systems appear archaic and promise better solubilization, protection during processing, improved shelf-life, higher bioavailability as well as controlled and targeted release. This review provides information on the state of knowledge on β-carotene nanodelivery systems adopted for developing functional foods, depicting their classifications, compositions, preparation methods, challenges, release and absorption of β-carotene in the gastrointestinal tract (GIT) and possible risks and future prospects.


2003 ◽  
Vol 807 ◽  
Author(s):  
T. Advocat ◽  
F. Jorion ◽  
T. Marcillat ◽  
G. Leturcq ◽  
X. Deschanels ◽  
...  

ABSTRACTZirconolite is a potential inorganic matrix that is currently investigated in France, in the framework of the 1991 radioactive waste management law, with a view to provide durable containment of the trivalent and tetravalent minor actinides like neptunium, curium, americium and small quantities of unrecyclable plutonium separated from other nuclear waste. To confirm the actinide loading capacity of the zirconolite calcium site and to study the physical and chemical stability of this type of ceramic when subjected to alpha self-irradiation, zirconolite ceramic pellets were fabricated with 10 wt% plutonium oxide (isotope 239 or 238). The 55 pellets are dense (> 93.3% of the theoretical density on average) and free of cracks. They are characterized by a grain size of between 10 and 20 micrometers. X-ray diffraction analyses confirmed the presence of the zirconolite 2M crystalline structure.


Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3610
Author(s):  
Jialin Yu ◽  
Huayu Qiu ◽  
Shouchun Yin ◽  
Hebin Wang ◽  
Yang Li

Pluronic polymers (pluronics) are a unique class of synthetic triblock copolymers containing hydrophobic polypropylene oxide (PPO) and hydrophilic polyethylene oxide (PEO) arranged in the PEO-PPO-PEO manner. Due to their excellent biocompatibility and amphiphilic properties, pluronics are an ideal and promising biological material, which is widely used in drug delivery, disease diagnosis, and treatment, among other applications. Through self-assembly or in combination with other materials, pluronics can form nano carriers with different morphologies, representing a kind of multifunctional pharmaceutical excipients. In recent years, the utilization of pluronic-based multi-functional drug carriers in tumor treatment has become widespread, and various responsive drug carriers are designed according to the characteristics of the tumor microenvironment, resulting in major progress in tumor therapy. This review introduces the specific role of pluronic-based polymer drug delivery systems in tumor therapy, focusing on their physical and chemical properties as well as the design aspects of pluronic polymers. Finally, using newer literature reports, this review provides insights into the future potential and challenges posed by different pluronic-based polymer drug delivery systems in tumor therapy.


2015 ◽  
Vol 6 (3) ◽  
pp. 2102-2109 ◽  
Author(s):  
Yue Zhang ◽  
Fangmao Ye ◽  
Wei Sun ◽  
Jiangbo Yu ◽  
I-Che Wu ◽  
...  

This paper describes photocrosslinkable Pdots with enhanced colloidal, physical, and chemical stability, and excellent encapsulating ability of functional small molecules.


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