scholarly journals Evaluation of Economic Impact of tuberculosis control In Malaysia Using Dynamic Transmission Model

2015 ◽  
Vol 18 (3) ◽  
pp. A244
Author(s):  
W.H. Fun ◽  
D.B. Wu ◽  
Y.M. Cheong ◽  
N. Mohamad Noordin ◽  
K.K. Lee
Keyword(s):  
Economic Impact ◽  
Transmission Model ◽  
Tuberculosis Control ◽  
Dynamic Transmission Model

The Effect of Thermo-Hydrodynamics on Manual Automotive Transmissions Gear Rattle

2009 ◽  
Author(s):  
Miguel De la Cruz ◽  
Stephanos Theodossiades ◽  
Homer Rahnejat ◽  
Patrick Kelly
Keyword(s):  
Contact Stiffness ◽  
Hertzian Contact ◽  
Transmission Model ◽  
System Response ◽  
Common Denominator ◽  
Gear Teeth ◽  
Lubricated Contacts ◽  
Engine Order ◽  
Dynamic Transmission Model ◽  
Gear Rattle

Manual transmission gear rattle is the result of repetitive impacts of gear meshing teeth within their backlash. This NVH phenomenon is a major industrial concern and can occur under various loaded or unloaded conditions. It fundamentally differs from other transient NVH phenomena, such as clonk or thud, which are due to impulsive actions. However, they all have their lowest common denominator in the action of contact/impact forces through lubricated contacts. Various forms of rattle have, therefore, been defined: idle rattle, drive rattle, creep rattle and over-run rattle. This paper presents a dynamic transmission model for creep rattle conditions (engaged gear at low engine RPM). The model takes into account the lubricated impact force between a gear teeth pair during a meshing cycle as well as the friction between their flanks. Hertzian contact conditions are applied to the gear pair along the torque path. Additionally, isoviscous hydrodynamic regime of lubrication is assumed for unselected (loose gear pairs) with lightly loaded impact conditions. The highly non-linear impacts induce a range of system response frequencies. These include engine order harmonics, harmonics of meshing frequency and natural frequencies related to contact stiffness. The last of these are dependent on the contact geometry and lubricant rheology. The analysis includes lubricant viscosity variation due to generated contact pressures as well as temperature. For loose gears, subject to oscillations on their retaining bearings, bearing friction is also considered.

scholarly journals Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England

Science ◽  
2021 ◽  
Vol 372 (6538) ◽  
pp. eabg3055 ◽  
Author(s):  
Nicholas G. Davies ◽  
Sam Abbott ◽  
Rosanna C. Barnard ◽  
Christopher I. Jarvis ◽  
Adam J. Kucharski ◽  
...  
Keyword(s):  
United States ◽  
Severe Acute Respiratory Syndrome ◽  
Reproduction Number ◽  
The United States ◽  
Control Measures ◽  
Transmission Model ◽  
Educational Institutions ◽  
Stringent Control ◽  
Dynamic Transmission Model ◽  
Credible Intervals

A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant, VOC 202012/01 (lineage B.1.1.7), emerged in southeast England in September 2020 and is rapidly spreading toward fixation. Using a variety of statistical and dynamic modeling approaches, we estimate that this variant has a 43 to 90% (range of 95% credible intervals, 38 to 130%) higher reproduction number than preexisting variants. A fitted two-strain dynamic transmission model shows that VOC 202012/01 will lead to large resurgences of COVID-19 cases. Without stringent control measures, including limited closure of educational institutions and a greatly accelerated vaccine rollout, COVID-19 hospitalizations and deaths across England in the first 6 months of 2021 were projected to exceed those in 2020. VOC 202012/01 has spread globally and exhibits a similar transmission increase (59 to 74%) in Denmark, Switzerland, and the United States.

scholarly journals Mathematical Models for Assessing Vaccination Scenarios in Several Provinces in Indonesia

2020 ◽  
Author(s):  
N. Nuraini ◽  
K. Khairudin ◽  
P. Hadisoemarto ◽  
H. Susanto ◽  
A. Hasan ◽  
...  
Keyword(s):  
Mathematical Models ◽  
Age Groups ◽  
Transmission Model ◽  
West Java ◽  
Dynamic Transmission Model ◽  
Simulation Results ◽  
Age Structured

AbstractTo mitigate more casualties from the COVID-19 outbreak, this study assessed optimal vaccination scenarios, considering some existing healthcare conditions and some assumptions, by developing SIQRD (Susceptible-Infected-Quarantine-Recovery-Death) models for Jakarta, West Java, and Banten, in Indonesia. The models included an age-structured dynamic transmission model that naturally could give different treatments among age groups of population. The simulation results show that the timing and period’s length of the vaccination should be well planned and prioritizing particular age groups will give significant impact on the total number of casualties.

Multi-objective optimization of hydro-viscous flexible drive for dynamic characteristics using genetic algorithm

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Jianzhong Cui ◽  
Hu Li ◽  
Dong Zhang ◽  
Yawen Xu ◽  
Fangwei Xie
Keyword(s):  
Genetic Algorithm ◽  
Dynamic Characteristics ◽  
Transmission Efficiency ◽  
Outer Radius ◽  
Transmission Model ◽  
Design Parameters ◽  
Multi Objective Optimization ◽  
Content Type ◽  
Multi Objective ◽  
Dynamic Transmission Model

Purpose The purpose of this study is to investigate the flexible dynamic characteristics about hydro-viscous drive providing meaningful insights into the credible speed-regulating behavior during the soft-start. Design/methodology/approach A comprehensive dynamic transmission model is proposed to investigate the effects of key parameters on the dynamic characteristics. To achieve a trade-off between the transmission efficiency and time proportion of hydrodynamic and mixed lubrication, a multi-objective optimization of friction pair system by genetic algorithm is presented to obtain the optimal combination of design parameters. Findings Decreasing the engagement pressure or the ratio of inner and outer radius, increasing the lubricating oil viscosity or the outer radius will result in the increase of time proportion of hydrodynamic and mixed lubrication, as well as the transmission efficiency and its maximum value. After optimization, main dynamic parameters including the oil film thickness, angular velocity of the driven disk, viscous torque and total torque show remarkable flexible transmission characteristics. Originality/value Both the dynamic transmission model and multi-objective optimization model are established to analyze the effects of main design parameters on the dynamic characteristics of hydro-viscous flexible drive.

scholarly journals Agent-based modelling study of antimicrobial-resistant Neisseria gonorrhoeae transmission in men who have sex with men: towards individualised diagnosis and treatment

Sexual Health ◽  
2019 ◽  
Vol 16 (5) ◽  
pp. 514 ◽  
Author(s):  
Adam K. Zienkiewicz ◽  
Nicolás Verschueren van Rees ◽  
Martin Homer ◽  
Jason J. Ong ◽  
Hannah Christensen ◽  
...  
Keyword(s):  
Index Case ◽  
Point Of Care ◽  
New Technology ◽  
Drug Dose ◽  
Transmission Model ◽  
Contact Network ◽  
Global Public Health ◽  
Reference Case ◽  
Dynamic Transmission Model ◽  
Sex With Men

Background Antimicrobial-resistant (AMR) gonorrhoea is a global public health threat. Discriminatory point-of-care tests (POCT) to detect drug sensitivity are under development, enabling individualised resistance-guided therapy. Methods: An individual-based dynamic transmission model of gonorrhoea infection in MSM living in London has been developed, incorporating ciprofloxacin-sensitive and resistant strains. The time-dependent sexual contact network is captured by periodically restructuring active connections to reflect the transience of contacts. Different strategies to improve treatment selection were explored, including discriminatory POCT and selecting partner treatment based on either the index case or partner susceptibility. Outcomes included population prevalence of gonorrhoea and drug dose counts. Results: It is shown that using POCT to detect ciprofloxacin-sensitive infections could result in a large decrease in ceftriaxone doses (by 70% compared with the reference case in the simulations of this study). It also suggests that ceftriaxone use can be reduced with existing technologies, albeit to a lesser degree; either using index case sensitivity profiles to direct treatment of partners, or testing notified partners with strain discriminatory laboratory tests before treatment, reduced ceftriaxone use in our model (by 27% and 47% respectively). Conclusions: POCT to detect ciprofloxacin-sensitive gonorrhoea are likely to dramatically reduce reliance on ceftriaxone, but requires the implementation of new technology. In the meantime, the proportion of unnecessary ceftriaxone treatment by testing partners before treatment could be reduced significantly. Alternatively, index case sensitivity profiles could be used to select effective treatments for partners.

Cost-effectiveness of influenza control measures: a dynamic transmission model-based analysis

2013 ◽  
Vol 141 (12) ◽  
pp. 2581-2594 ◽  
Author(s):  
S.-C. CHEN ◽  
C.-M. LIAO
Keyword(s):  
Cost Effectiveness ◽  
Natural Ventilation ◽  
Seasonal Influenza ◽  
School Setting ◽  
Control Measures ◽  
Transmission Model ◽  
Model Based ◽  
Dynamic Transmission Model ◽  
Influenza Transmission ◽  
The Cost

SUMMARYWe investigated the cost-effectiveness of different influenza control strategies in a school setting in Taiwan. A susceptible-exposure-infected-recovery (SEIR) model was used to simulate influenza transmission and we used a basic reproduction number (R0)–asymptomatic proportion (θ) control scheme to develop a cost-effectiveness model. Based on our dynamic transmission model and economic evaluation, this study indicated that the optimal cost-effective strategy for all modelling scenarios was a combination of natural ventilation and respiratory masking. The estimated costs were US$10/year per person in winter for one kindergarten student. The cost for hand washing was estimated to be US$32/year per person, which was much lower than that of isolation (US$55/year per person) and vaccination (US$86/year per person) in containing seasonal influenza. Transmission model-based, cost-effectiveness analysis can be a useful tool for providing insight into the impacts of economic factors and health benefits on certain strategies for controlling seasonal influenza.

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