Engineering in modern medicine using ‘magnetic nanoparticles’ in understanding physicochemical interactions at the nano–bio interfaces

2022 ◽  
Vol 23 ◽  
pp. 100733
Author(s):  
Y.-S. Borghei ◽  
S. Hosseinkhani ◽  
M.R. Ganjali
Keyword(s):  
Magnetic Nanoparticles ◽  
Modern Medicine ◽  
Physicochemical Interactions

A Novel Remote Controllable Drug Delivery System Triggered by Heating From Magnetic Nanoparticles

2009 ◽  
Author(s):  
Xiaoliang Wang ◽  
Hongchen Gu ◽  
Xinyuan Zhu
Keyword(s):  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Drug Targeting ◽  
New Technology ◽  
Modern Medicine ◽  
Target Drug Delivery ◽  
Target Drug ◽  
Long Time ◽  
Magnetic Filed ◽  
Core Issues

Target drug delivery is one of the core issues in modern medicine. Although both thermo-sensitive and magnetic drug vehicles have been developed for this purpose, reliable drug targeting is yet to achieve, because it’s hard to control local temperature in body for thermo-sensitive drugs, and it’s also difficult to control the colloidal sizes of magnetic vehicles to meet the requirements for both long-time circulation and magnetic responsibility. Here we present a new technology to solve these two problems. The drug (taxel) was combined with hyper-branched thermo-sensitive polymer and magnetic nanoparticles. Magnetic responsibility of the complex can be remotely controlled by applying an alternating magnetic field. The untreated complexes were stable in dispersion, while after exposing to the alternating magnetic filed for 5 minutes, the complexes were destabilized and deposited from dispersion quickly. Unlike the commonly used water bath, the technology present here can heat up the drug vehicles remotely from outside, which must have great potentials in the applications of magnetic or thermo-sensitive drug delivery.

Alkannins and Shikonins: From ancient codes to modern medicine

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
AN Assimopoulou ◽  
VP Papageorgiou
Keyword(s):  
Modern Medicine

Biotelemetry and Computer Analysis of Electrocardiograms

1969 ◽  
Vol 08 (03) ◽  
pp. 120-127 ◽  
Author(s):  
P. R. Amlinger
Keyword(s):  
Computer Analysis ◽  
Rural Areas ◽  
Applied Research ◽  
Research Effort ◽  
Pilot Project ◽  
Modern Medicine ◽  
Modern Technology ◽  
Long Distance ◽  
Regional Medical ◽  
Medical Program

Routine transmission of electrocardiograms and their computer interpretation via long-distance telephone lines has been proven feasible in the Automated Electrocardiogram Project of the Missouri Regional Medical Program. Though this Pilot Project — the first on a state-wide basis — is still viewed as an applied research effort rather than a service, such biotelemetry is rapidly gaining acceptance as a medium to bring modern medicine, through modern technology, to urban and remote rural areas as well, where it is most needed.The computer executes all the wave measuraments and calculations with incredible speed. It takes over a most boring, repetitive part of the physician’s work. However, it can only follow the instructions of the diagnostic program, compiled by expert cardiologists. Thus, it is an ever-ready, never-tiring servant for the physician and his patients.

Herba Reudeuep With Modification of Heating In Virgin Cocanut Oil

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Wahyuzan Wahyuzan ◽  
Lukmanul Hakim ◽  
Rahmat Afrizal ◽  
Asmeri Lamona ◽  
Khairuni Khairuni ◽  
...  
Keyword(s):  
Modern Medicine ◽  
Heating Time ◽  
Agricultural Product ◽  
Average Yield ◽  
Herbal Products ◽  
The Public ◽  
Randomized Design ◽  
Herbal Plants ◽  
Medicinal Properties ◽  
Completely Randomized Design

Traditional medicine in Indonesia has been known by the public before formal health services using modern medicine. Indonesia has many type of herbal plants which have medicinal properties including dadap (Erythrina orientalis). This study aims to utilized dadap herbal liniment by modifying heating in Vigin Cocanut Oil. The study conducted in the laboratory of Agricultural Product Processing using a Factorial Completely Randomized Design (CRD). The first factor is the addition of 250 ml (M1), 375 ml (m2), and 400 ml (M3) Virgin Cocanut Oil treatment. The second factor is the heating tim of 5 minutes (L1), 10 minutes (L2), and 15 minutes (L3). Observation variable consisted of yield, Specific gravity, and organoleptic test of aroma and colored. The result showed an average yield of 87.70-91.88%. The highest yield was found in the treatment of adding 400 ml Virgin Cocanut Oil and 15 minutes of heating time. The highest type of weight was found in the treatment of addition of 325 ml Virgin Cocanut Oil and 5 minutes heating time. Based on the organoleptic scent test, the everage penalist gives a like answer. Organoleptic colors of reudeuep herbal products is according to SNI number 06-23-2006.

Language Matters: ‘Counsel’ in Early Modern and Modern Medicine

2018 ◽  
Author(s):  
Ian Sabroe ◽  
Phil Withington
Keyword(s):  
Seventeenth Century ◽  
Early Modern ◽  
Scientific Revolution ◽  
Modern Medicine ◽  
Francis Bacon ◽  
Social Worlds ◽  
Founding Fathers ◽  
Human Understanding ◽  
Successful Scientist

Francis Bacon is famous today as one of the founding fathers of the so-called ‘scientific revolution’ of the seventeenth century. Although not an especially successful scientist himself, he was nevertheless the most eloquent and influential spokesperson for an approach to knowledge that promised to transform human understanding of both humanity and its relationship with the natural and social worlds. The central features of this approach, as they emerged in Bacon’s own writings and the work of his protégés and associates after 1605, are equally well known. They include the importance of experiment, observation, and a sceptical attitude towards inherited wisdom (from the ‘ancients’ in general and Aristotle in particular).

Clinical case of periostitis in pregnant women complicated by sepsis

2020 ◽  
pp. 61-63
Author(s):  
S. Sh. Kakvaeva ◽  
M. A. Magomedova ◽  
A. N. Dzhalilova
Keyword(s):  
Pregnant Woman ◽  
Multiple Organ Failure ◽  
Pregnant Women ◽  
Organ Failure ◽  
Clinical Case ◽  
Clinical Observation ◽  
Infectious Agent ◽  
Modern Medicine ◽  
Multiple Organ ◽  
Number Of Patients

One of the most serious problems of modern medicine is sepsis. The number of patients undergoing this complication is 20–30 million (WHO) annually and has no tendency to decrease. Sepsis is characterized by severe multiple organ failure due to a violation of the response of the macroorganism to an infectious agent. Moreover, it is dangerous with high mortality. Sepsis often develops in patients with immunodeficiency conditions, which primarily include pregnant women. The article presents a clinical observation of a case of periostitis in a pregnant woman complicated by a septic state.

The effects and use of negative pressure wound therapy – a set of case reports

2020 ◽  
Vol 99 (4) ◽  
pp. 183-188
Keyword(s):  
Wound Healing ◽  
High Risk ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Chronic Wounds ◽  
Wide Spectrum ◽  
Case Reports ◽  
Modern Medicine ◽  
Wound Therapy ◽  
Basic Set

Modern medicine offers a wide spectrum of wound healing resources for acute or chronic wounds. Negative pressure wound therapy (NPWT) is a very effective method, allowing complicated defects and wounds to heal. The basic set is usually provided with various special accessories to facilitate the use and support safe application of NPWT to high-risk tissue. Selected case reports are presented herein to document the special use and combinations of materials in negative pressure wound therapy.

Participation of ABCA1 transporter in development of chronic obstructive pulmonary disease

2020 ◽  
Vol 28 (3) ◽  
pp. 360-370
Author(s):  
Stanislav N. Kotlyarov ◽  
Anna A. Kotlyarova
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Significant Contribution ◽  
Modern Medicine ◽  
Lipid Homeostasis ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Reverse Transport ◽  
Current Paradigm

Despite all achievements of the modern medicine, the problem of chronic obstructive pulmonary disease (COPD) does not lose its relevance. The current paradigm suggests a key role of macrophages in inflammation in COPD. Macrophages are known to be heterogeneous in their functions. This heterogeneity is determined by their immunometabolic profile and also by peculiarities of lipid homeostasis of cells. Aim. To analyze the role of the ABCA1 transporter, a member of the ABC A subfamily, in the pathogenesis of COPD. The expression of ABCA1 in lung tissues is on the second place after the liver, which shows the important role of the carrier and of lipid homeostasis in the function of lungs. Analysis of the literature shows that participation of the transporter in inflammation consists in regulation of the content of cholesterol in the lipid rafts of the membranes, in phagocytosis and apoptosis. Conclusion. Through regulation of the process of reverse transport of cholesterol in macrophages of lungs, ABCA1 can change their inflammatory response, which makes a significant contribution to the pathogenesis of COPD.

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