K1. Global trends in oral cancer burden and control

Abstract Background HIV/AIDS is a critical public health concern worldwide. This article aimed to demonstrate th trends of HIV/AIDS burden from 1990 to 2019.Methods Data was extracted from the Global Burden of Disease study (GBDs) 2019. Estimated annual percentage change (EAPC) and age-standardized rate (ASR) were estimated to quantify the trends at global, regional and national levels.Results During the period 1990-2004, the trend in incidence of HIV/AIDS was stable globally. Whereas the trends in prevalence, death and disability-adjusted life years (DALYs) had pronounced increasing trends, with the respective EAPCs were 7.47 (95%confidence interval [CI]: 5.84 to 9.12), 10.85(95%CI: 8.90 to 12.84), and 10.40(95%CI: 8.47 to 12.36). Meanwhile, the pronounced increasing trends were seen in low-resource settings, particularly that of death in Oceania and South Asia, in which the respective EAPCs were 44.76 (95%CI: 40.81 to 48.82) and 40.82 (95%CI: 34.31 to 47.64). However, the global trends in incidence, death and DALYs of HIV/AIDS pronouncedly decreased from 2005 to 2019, with the respective EAPCs were −2.68(95%CI: −2.82 to −2.53), −6.73(95%CI: −6.98 to −6.47) and −6.75(95%CI: −6.95 to −6.54). Whereas prevalence showed increasing trend (EAPC: 0.71, 95%CI: 0.54 to 0.87). Decreasing trends of HIV/AIDS were observed in most regions and countries, particularly that of death and DALYs in Burundi respectively were −15.28 (95%CI: −16.08 to −14.47) and −15.07 (95%CI: −15.79 to −14.33). Conclusions Decreasing trends of HIV/AIDS were observed worldwide over the past 15 years. However, HIV/AIDS remains one of the most critical causes of health loss worldwide, which emphasized the effective prevention and control strategies.

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Investment marketing strategy for diversified enterprises

Economic Analysis ◽

10.35774/econa2019.04.146 ◽

2019 ◽

pp. 146-152

Author(s):

Oleksandr Kalinin

Keyword(s):

Business Models ◽

Growth Strategy ◽

Entrepreneurial Activity ◽

Global Trends ◽

Scientific Methods ◽

Goods And Services ◽

Analysis And Synthesis ◽

General Scientific ◽

And Control ◽

The Impact

Introduction The amount of capital that individual, corporate and institutional investors are willing to invest in certain assets is increasing every year. This leads to a revitalization of entrepreneurial activity and growth of the economy as a whole. It is also very active in creating certain disparities in the distribution of investment flows at the cross-sectoral level. There are industries that perceive investors more positively, and other industries perceive less positively. Among these industries, and even more types of businesses, are diversified companies or conglomerates that are perceived by investors as a chaotic set of assets that management is unable to manage effectively. Purpose The purpose of this article is to study the global trends in managing strategies for competitive advantage in the capital market by diversified enterprises. The purpose of the article is to study the theoretical aspects of management and planning the choice of growth strategy for diversified enterprises; to analyze the systems of strategic management of investment marketing for diversified companies; develop solutions to improve the marketing management system for various companies in the context of attracting investment. Method (methodology) In the course of the research, the following general scientific methods are used: analysis and synthesis, grouping and systematization of revealing the essence of investment marketing, its structure, principles of its formation, development of the concept of diagnostics of efficiency of investor attraction systems and control of this process; induction and deduction - to summarize the theoretical aspects of the peculiarities of the formation of the structure of investment marketing; statistical and economic - to evaluate the investment attractiveness of a diversified enterprise. Results It was suggested to the conglomerate companies to distance their company brand from its subsidiaries as much as possible so that there was no problem in identifying the main focus of the conglomerate's business activity. For the analysis of companies that should be considered for placement of their own and borrowed funds by conglomerates and to demonstrate this investment policy, investors can distinguish the following areas of analysis of potential companies: whether the leadership of a company in a particular segment can lead to the possibility of controlling the pricing of goods or / or company services; whether it is possible to create a competitive business through the attraction of additional investment opportunities. Thus, solving the problem of finances, and more precisely the ability to run a business for a certain time, can bring to positive indicators of profit and return on invested capital; the impact on the aggregate industry reserve of profits, which makes it possible to receive more profit from the industry of related fields from consumers than competitors can, thus ensuring long-term competitiveness. Also regarding the display of client base of goods and services that we can distinguish for investors is: demonstrating the presence of privileged clients; the existence of diversified profit strategies; availability of special copy - protected goods and business models; the presence of unique and difficult to copy distribution and communication channels; the presence of barriers to competitors (patents. Brand, licensing, large investments in market entry, etc.).

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Correlation of Arsenic Levels in Smokeless Tobacco Products and Biological Samples of Oral Cancer Patients and Control Consumers

Biological Trace Element Research ◽

10.1007/s12011-015-0355-y ◽

2015 ◽

Vol 168 (2) ◽

pp. 287-295 ◽

Cited By ~ 4

Author(s):

Sadaf S. Arain ◽

Tasneem G. Kazi ◽

Hassan I. Afridi ◽

Farah N. Talpur ◽

Atif G. Kazi ◽

...

Keyword(s):

Oral Cancer ◽

Cancer Patients ◽

Smokeless Tobacco ◽

Biological Samples ◽

Tobacco Products ◽

Smokeless Tobacco Products ◽

Oral Cancer Patients ◽

And Control

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Oral cancer in Brazil: a secular history of Public Health Policies

RGO - Revista Gaúcha de Odontologia ◽

10.1590/1981-8637201400020000091688 ◽

2014 ◽

Vol 62 (2) ◽

pp. 159-164

Author(s):

Paulo Ricardo Saquete MARTINS FILHO ◽

Thiago de Santana SANTOS ◽

Luiz Carlos Ferreira da SILVA ◽

Marta Rabello PIVA

Keyword(s):

Public Health ◽

Oral Cancer ◽

Low Income ◽

Cancer Control ◽

Public Health Issue ◽

History Of Public Health ◽

Assistance Programs ◽

Control Programs ◽

History Of ◽

And Control

The oral cancer in Brazil is considered an important public health issue. Despite almost a century of combat disease, with oncological assistance programs and prevention campaigns based public policies, the incidence of oral cancer in several regions is still high. The major goal of cancer prevention and control is a reduction in both the incidence of the disease and the associated morbidity and mortality, as well as improved life for cancer patients and their families. Low-income and disadvantage groups are generally more exposed to avoidable risk factors such as tobacco and alcohol consumption. These groups have less access to the health services and education that would empower them to make decisions to protect and improve their own health. Thus, cancer control programs are the most effective instrument to bridge the gap between knowledge and practice and achieve this goal. The authors report some key historical facts concerning the fight against oral cancer in Brazil, in addition to addressing the epidemiological aspects of disease.

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Evaluating the levels of D-dimer as a primary marker in oral cancers using immunoturbidimetric assay: The original research

International Journal of Molecular and Immuno Oncology ◽

10.25259/ijmio_11_2020 ◽

2020 ◽

Vol 5 ◽

pp. 96-100

Author(s):

Ashok K. Vikey ◽

Rajkumar Parwani ◽

Madhusudan Asteker ◽

Deepali Gupta ◽

Simran Parwani

Keyword(s):

Oral Cancer ◽

Cell Biology ◽

Control Group ◽

Original Research ◽

Oral Cancers ◽

Cancer Group ◽

Tissue Factors ◽

Dual Action ◽

And Control ◽

D Dimer

Objectives: Oral cancer is major health threat; with 90% mortality and ranks sixth among worldwide cancers. So to overcome this mortality; newer bio-markers are explored and one of such biomarker is D-dimer, which is end product of fibrinogen formed by plasmin. The raised levels of D-dimer play significant role in proliferation and progress of cancer cells. In cancers D-dimer is formed by dual action, where UPA (Urokinase type Plasminogen Activator) and Tissue factor play important role simultaneously. To understand correlation between D- dimer and oral cancers, by immunoturbidimetry; quantitative assay. Material and Methods: After obtaining consents of patients and Institutional ethical clearance, we randomly selected; age and sex matched; 216 samples. Further these samples were subdivides as oral cancer group and control group, consisting 108 samples in each group respectively. Results: Statistical analysis was done; using SPSS version 20, unpaired -T test, and one way ANOVA were applied. Plasma D-dimer levels were; 497.32±872.28μl/ml and 165.30±150.43 28μl/ml, among cancer and control groups respectively, (P≤ 0.0001), which was statistically highly significant. Conclusion: D-dimer is altered during carcinogenesis by activation of UPA and Tissue factors, and this distinguishes form routine levels of D-dimer. This suggests that, cancer cell biology is greatly affected by D-dimer levels during growth and spread of cancers. So raised levels of D-dimer can be considered during interventions of cancers, and incorporated as a biomarker. However for its scientific applications; there is need of further study, with collaborative approach and larger samples, to restrict cancer related mortalities.

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Global trends in the development of low-orbit space systems for optoelectronic Earth observation

Technical mechanics ◽

10.15407/itm2020.03.039 ◽

2020 ◽

Vol 2020 (3) ◽

pp. 39-53

Author(s):

O.L. Volosheniuk ◽

Keyword(s):

Orbit Space ◽

Earth Observation ◽

Transport Infrastructure ◽

Satellite Constellations ◽

Global Trends ◽

Foreign Companies ◽

The Usa ◽

Performance Capture ◽

Dynamics Models ◽

And Control

The aim of this work is to identify the global trends in the use of low-orbit spacecraft constellations, which have a number of substantial advantages in Earth remote sensing (ERS). Much attention is given to the construction of large constellations of single- and different-type spacecraft by foreign companies and operators, such as Digital Globe, Planet Labs, Black Sky, Satellogic S.A. etc., and to the plans of deployment of constellations of this type in the USA, China, Japan, Canada, Europe, and other countries. The characteristics of the various, mainly commercial, low-orbit constellations of optoelectronic Earth observation spacecraft put into orbit over the past five years are considered. It is shown that low-orbit spacecraft constellations can be used to good advantage in the solution of numerous socio-economic problems, such as geodesy and cartography, urban development, transport infrastructure, crop estimate, environmental monitoring, health monitoring, etc., and new problems aimed at prompt continuous monitoring of various objects. The paper presents a comparative analysis of the technical implementations and ways of achievement of the main target spacecraft characteristics, such as information performance, capture range, revisit time, geodetic connection accuracy, imaging immediacy, and the possibility of stereo and video imaging by satellite constellations. It is shown that the construction of large low-orbit constellations is a new trend in the world astronautics, which requires systematic methods for their design and control. The results obtained allows one to make recommendations on the design of low-orbit constellations of home ERS spacecraft, in particular on the development of orbit determination models and algorithms and spacecraft dynamics models.

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