Modified Quantitative Testing and QoL in Allergic Rhinitis

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P29-P29
Author(s):  
Charles S. Coffey ◽  
Richard J. Harvey ◽  
Jamie I. Woody ◽  
Sarah K. Koepp ◽  
Patrick Sheahan ◽  
...  

Objective (1) Assess the relationship between QoL, objective assessment and confounding factors. (2) Describe a model representing the severity of pathology and predicting potential responses from therapeutic interventions beyond Quality of Life measurements alone. Methods A cross-sectional study of allergic rhinitis (AR) patients, from a teritary rhinology clinic in 2007, with Modified Quantitative Testing (MQT) and Mini-Rhinoconjuctivitis Quality of Life Questionnaire (mRQLQ) assessments was performed. Correlation and regression analyses assessed the relationship of mRQLQ, MQT endpoints, and number of reactive antigens. Results 47 patients (53% female, mean age 36.0 ± 16.3yrs) were assessed. Percentage of positive antigens was a significant factor that decreased mRQLQ (p=0.05). Maximal MQT endpoint (mMQT) correlates well to mRQLQ when controlled for percentage of positive antigens (p=0.038). In a regression analysis to predict mRQLQ, percentage of positive antigens and mMQT were good predictors (p=0.018 for percent positive antigens; p=0.038 for mMQT) and such a model was significantly linked to those factors (F=3.2, p=0.05). Conclusions Semi-quantitative measurement by MQT correlates with symptom severity in AR when broad reactivity does not exist. Adaptation in QoL scores may occur with more atopic individuals. A model for predicting QoL and symptom severity as measured by mRQLQ based upon MQT is presented. Such systems may enhance our ability to predict clinical outcomes, compare research cohorts, and better educate patients on treatment benefits.

2016 ◽  
Vol 8 (10) ◽  
pp. 250 ◽  
Author(s):  
Mahnaz Solhi ◽  
Marziyeh Shabani Hamedan ◽  
Masood Salehi

<p><strong>BACKGROUND &amp; AIM</strong><strong>:</strong> Women heading their households are the ones who lead their life alone. Burden of life probably decreases the quality of life of women-headed households. The aim of this study is to determine the relationship between quality of life of women-headed households and some related factors in Iran.</p><p><strong>METHODS</strong><strong>:</strong> The study was a cross-sectional study and 180 women-head households were selected from Welfare Organization, Tehran Province, using stratified random sampling method in 2015(January up to April). Social World Health Organization's quality of life questionnaire was used to gather information. The data were analyzed using SPSS statistical software (15) and suitable descriptive and analytical methods were applied.</p><p><strong>RESULTS: </strong>Quality of life was moderate in the studied women. The <em>highest mean score </em>(50.35) <em>was</em> related to the physical aspect and the lowest <em>mean </em>(37.82) was about the environmental aspect.</p><p><strong>CONCLUSION:</strong> Quality of life of the studied women is not desirable; so, it is necessary to design appropriate interventions to improve their quality of life.</p>


2017 ◽  
Vol 4 (9) ◽  
pp. 1629 ◽  
Author(s):  
Rasoul Nasiri Kalmarzi ◽  
Zaher Khazaei ◽  
Jafar Shahsavar ◽  
Fardin Gharibi ◽  
Marzieh Tavakol ◽  
...  

Introduction: Chronic diseases, due to their prolonged and debilitating nature, dramatically affect patient quality of life. Allergic rhinitis (AR) is one of the most common chronic diseases. The present study aimed to determine quality of life in patients with allergic rhinitis in Western Iran. Methods: In a cross-sectional study, 146 patients with AR were enrolled in this study. The required data were collected using the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). The questionnaire was distributed among the patients by a physician and analysis of data was carried out by SPSS version 16. Results: Of the total of 146 AR patients admitted to the clinic, 61% were female and 39% were male; the mean age was 29±10.17. Rhinorrhea (82.2%) was the most common symptom, and moderate to severe intermittent rhinitis (38.4%) was the most common type of the disease. A dramatic reduction in quality of life was observed in 62% of the patients, and the severity of the disease significantly reduced the quality of life (P=0.000). Conclusion: Allergic rhinitis can adversely affect every aspect of a patient's life, including sleep quality, mood and daily activities.


2017 ◽  
Vol 135 (4) ◽  
pp. 332-338 ◽  
Author(s):  
Letícia Baltieri ◽  
Luiz Claudio Martins ◽  
Everton Cazzo ◽  
Débora Aparecida Oliveira Modena ◽  
Renata Cristina Gobato ◽  
...  

ABSTRACT CONTEXT AND OBJECTIVE: The combined effect of obesity and asthma may lead to significant impairment of quality of life (QOL). The aim here was to evaluate the prevalence of asthma among obese individuals, characterize the severity of impairment of quality of life and measure its relationship with pulmonary function. DESIGN AND SETTING: Observational cross-sectional study in public university hospital. METHODS: Morbidly obese individuals (body mass index &gt; 40 kg/m2) seen in a bariatric surgery outpatient clinic and diagnosed with asthma, were included. Anthropometric data were collected, the Standardized Asthma Quality of Life Questionnaire (AQLQ(S)) was applied and spirometry was performed. The subjects were divided into two groups based on the median of the score in the questionnaire (worse &lt; 4 and better &gt; 4) and were compared regarding anthropometric data and pulmonary function. RESULTS: Among the 4791 individuals evaluated, 219 were asthmatic; the prevalence of asthma was 4.57%. Of these, 91 individuals were called to start multidisciplinary follow-up during the study period, of whom 82 answered the questionnaire. The median score in the AQLQ(S) was 3.96 points and, thus, the individuals were classified as having moderate impairment of their overall QOL. When divided according to better or worse QOL, there was a statistically difference in forced expiratory flow (FEF) 25-75%, with higher values in the better QOL group. CONCLUSION: The prevalence of asthma was 4.57% and QOL was impaired among the asthmatic obese individuals. The worst QOL domain related to environmental stimuli and the best QOL domain to limitations of the activities. Worse QOL was correlated with poorer values for FEF 25-75%.


2018 ◽  
Vol 7 (10) ◽  
pp. 323 ◽  
Author(s):  
Jerzy Konstantynowicz ◽  
Pawel Abramowicz ◽  
Wojciech Glinkowski ◽  
Ewa Taranta ◽  
Ludmila Marcinowicz ◽  
...  

Recently, SarQoL® (Sarcopenia and Quality of Life), a quality of life (QoL) questionnaire specific to sarcopenia, was successfully developed. For practical reasons, there is a great interest in validating this questionnaire in other populations. The aim of this cross-sectional study was to translate and adjust the SarQoL® into Polish and to standardize the validity of this method for the assessment of sarcopenic individuals in Poland with regard to psychometric properties. The English version was used for the translation process. A total of 106 community-dwelling Caucasian subjects aged 73.3 ± 5.94 years (65.1% females) were studied, with 60 participants being diagnosed sarcopenic. The translation and cross-cultural adaptation was carried out in five phases according to specific standard guidelines. There were no major linguistic issues in the translation process. The data confirmed a good discriminant validity, i.e., significantly lower scores for all domains (reduced global QoL in sarcopenic subjects compared to non-sarcopenic ones; 54.9 ± 16.5 vs. 63.3 ± 17.1, p = 0.013), and high internal consistency (Cronbach’s alpha coefficient was 0.92). The significant correlation of the SarQoL® scores with those of other questionnaires (SF-36v2® Health Survey and EuroQoL-5-Dimension) that are supposed to have similar dimensions indicated the consistent construct validity of the SarQoL®-PL questionnaire. No floor/ceiling effects were found. An excellent agreement was found between the test and the re-test (intraclass coefficient correlation (ICC): 0.99). The first Polish version of the SarQoL® questionnaire is valid and consistent and therefore may be used with reliability for clinical and research purposes regarding QoL assessment of sarcopenic individuals. However, further research, in particular prospective studies, is needed to determine potential limitations and the suitability of the new tool for the Polish scenario and specificity.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Sarah Raes ◽  
Sophie Vandepitte ◽  
Delphine De Smedt ◽  
Herlinde Wynendaele ◽  
Yannai DeJonghe ◽  
...  

Abstract Background Knowledge about the relationship between the residents’ Quality of Life (QOL) and the nursing home price is currently lacking. Therefore, this study investigates the relationship between 11 dimensions of QOL and nursing homes price in Flemish nursing homes. Methods The data used in this cross-sectional study were collected by the Flemish government from years 2014 to 2017 and originates from 659 Flemish nursing homes. From 2014 to 2016, data on the QOL of 21,756 residents was assessed with the InterRAI instrument. This instrument contains 11 QOL dimensions. Multiple linear regression analyses were conducted to examine the research question. Results The multiple linear regressions indicated that a 10 euro increase in the daily nursing home price is associated with a significant decrease (P <  0.001) of 0.1 in 5 dimensions of QOL (access to services, comfort and environment, food and meals, respect, and safety and security). Hence, our results indicate that the association between price and QOL is very small. When conducting a subgroup analysis based on ownership type, the earlier found results remained only statistically significant for private nursing homes. Conclusion Our findings show that nursing home price is of limited importance with respect to resident QOL. Contrary to popular belief, our study demonstrates a limited negative effect of price on QOL. Further research that includes other indicators of QOL is needed to allow policymakers and nursing home managers to improve nursing home residents’ QOL.


2019 ◽  
Vol 31 (4) ◽  
pp. 213-218 ◽  
Author(s):  
Nooshin Masoudian ◽  
Mohammad Sarmadi ◽  
Rasool Najafi ◽  
Fereshteh Najafi ◽  
Shirin Maleki

The purpose of this study was to investigate the relationship between Burden of Care and Quality of Life in informal home caregivers of stroke patients in Iran. Also we were trying to explore the factors that affect the burden of care. In this cross-sectional study, we have selected 62 informal home caregivers of the patients admitted to “the stroke outpatient unit of the neurology clinic” of the central hospital in Semnan province, Iran, to take part in the investigation. We interviewed them using the Caregiver Burden Inventory and SF-36 Questionnaire for assessing their quality of life. There was a negative and significant correlation between different aspects of quality of life and burden of care. In the bivariate regression model, being married and having lower levels of education (minimum years of schooling) were associated with higher levels of the burden. Our study shows that increasing burden of care in informal home caregivers reduces the quality of life in all domains. Thus, the results of this study indicate that an increase in the burden of caregiving on caregivers lowers their quality of life in all aspects; especially, caregivers who provide care to their spouses encountered more burden. Therefore, these caregivers must be in the center of interest while planning to reduce the burden of care.


2005 ◽  
Vol 90 (6) ◽  
pp. 3337-3341 ◽  
Author(s):  
Susannah V. Rowles ◽  
L. Prieto ◽  
X. Badia ◽  
Steven M. Shalet ◽  
Susan M. Webb ◽  
...  

Acromegaly Quality of Life Questionnaire (AcroQoL) is a new disease-generated quality of life (QOL) questionnaire comprising 22 questions covering physical and psychological aspects of acromegaly and subdivided into “appearance” and “personal relations” categories. We have performed a cross-sectional study of QOL in 80 patients [43 male (mean age, 54.2 yr; range, 20–84); median GH, 0.93ng/ml (range, &lt;0.3 to 23.7); IGF-I, 333.1 ng/ml (range, 47.7–899)] with acromegaly. In addition to AcroQoL, patients completed three generic QOL questionnaires: Psychological General Well-Being Schedule (PGWBS), EuroQol, and a signs and symptoms score (SSS). All three generic questionnaires confirmed impairment in QOL [mean scores: PGWBS, 69.6; EuroQol, visual analog scale, 66.4 (range, 20–100) and utility index, 0.7 (range, −0.07 to 0.92); and SSS, 12 (range, 0–27)]. There was no correlation between biochemical control and any measure of QOL. AcroQoL (57.3%; range, 18.2–93.2) correlated with PGWBS (r = 0.73; P &lt; 0.0001); and in patients with active disease, AcroQoL-physical dimension correlated with SSS (r = −0.67; P &lt; 0.0003). In all questionnaires, prior radiotherapy was associated with impaired QOL. In conclusion, these data underline the marked impact that acromegaly has on patients’ QOL and provide the first evidence validating AcroQoL against well-authenticated measures of QOL. This indicates the potential of AcroQoL as a patient-friendly measure of disease activity.


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