The relationship between vitamin D and moderate/severe persistent allergic rhinitis

Author(s):  
P. Xiong ◽  
H. Wu ◽  
F. Wang ◽  
Q. Lu ◽  
B. Liu ◽  
...  
2018 ◽  
Vol 6 (8) ◽  
pp. 1405-1409 ◽  
Author(s):  
Lia Restimulia ◽  
Dwi Reno Pawarti ◽  
Haris Mayaguyang Ekorini

BACKGROUND: Allergic diseases and vitamin D deficiency were found to have a relationship. However, there was limited number of studies on the relationship between vitamin D with allergic rhinitis (AR) and total nasal symptom scores (TNSS), particularly in determining the cut-off points of serum vitamin D levels which correlated to AR.AIM: As this particular study has never been conducted in Indonesia, the main objective of this study was to investigate this issue.METHODS: The research was conducted at Dr Soetomo Hospital, Surabaya in January 2017. A group of 30 subjects were recruited using consecutive sampling. Levels of serum vitamin D were measured using electrochemiluminescence immunoassay (ECLIA) method while the total nasal symptom scores were obtained by accumulating all the nasal symptoms. Data of serum vitamin D levels and TNSS were analysed statistically with the Pearson correlation test.RESULTS: It was found that the mean of serum 25(OH) vitamin D levels (9.13 ng/mL) of the AR group was significantly lower than the non-AR group (26.22 ng/mL) (P = 0.000). The vitamin D cut-off points which correlated to AR was about 12.83 ng/mL (sensitivity = 80%; specificity = 100%). A Pearson correlation test found a strong, negative correlation between vitamin D levels and TNSS (P = 0.000; r = -0.800).CONCLUSION: There was a strong, negative correlation between serum vitamin D levels with AR and TNSS. The cut-off points of serum vitamin D levels correlated to AR were approximately12.83 ng/mL. Thus, further research needs to be conducted.


2019 ◽  
Vol 40 (2) ◽  
pp. 173-178 ◽  
Author(s):  
Shaghayegh Shahsavan ◽  
Ashkan Pirayesh ◽  
Omid Zargari Samani ◽  
Hedayatollah Shirzad ◽  
Mohamad Ali Zamani ◽  
...  

2021 ◽  
Vol 9 (E) ◽  
pp. 1109-1114
Author(s):  
S. B. Dyussenova ◽  
M. Y. Gordiyenko ◽  
M. S. Askarov ◽  
G. K. Tuleuova ◽  
S. B. Suleimenova ◽  
...  

Clinical studies and meta-analyzes have shown that reduced levels of 25 (OH) D in the blood contribute to impaired immunity and stimulate excessive inflammation that adversely affects the health of children: the risk of developing bronchial asthma (BA), obstructive bronchitis, and allergic rhinitis increases. The main purpose of this review is to summarize the current literature data on the relationship between vitamin D, VRI and other infectious diseases with a clinical example.


2016 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Roy David Sarumpaet ◽  
Mohammad Juffrie ◽  
Suprihati . ◽  
Indwiani Astuti

ABSTRAK Pendahuluan: Pengaruh asap rokok pada penderita Rinitis Alergi Persisten (RAP) yang prevalensinya semakin meningkat di Indonesia belum mendapat perhatian untuk diteliti, meskipun jumlah penduduk yang merokok semakin bertambah. Tujuan: Menganalisis hubungan asap rokok “side-stream” (SS)  dengan  perubahan kualitas hidup (KH) total penderita Rinitis Alergi Persisten (RAP).  Metode: Penelitian ini adalah dengan desain kasus kontrol, dimana 63  penderita RAP  sedang-berat yang dibuktikan dengan tes alergi dibagi menjadi kelompok perlakuan (32) dan kontrol (31) secara acak. 32 penderita RAP dipaparkan dengan asap rokok (SS) dari 5 batang rokok selama 2 jam dalam  suatu  ruangan. Seluruh responden diminta mengisi kuesioner kualitas hidup dari Juniper’s RQLQ. Hasil: KH total antara kelompok perlakuan dengan kontrol tidak berbeda bermakna. KH total yang terpapar asap rokok setiap hari  berbeda bermakna. Diskusi: Asap rokok yang dipaparkan pada penderita RAP tidak menyebabkan perubahan kualitas hidup.ABSTRACT Introduction: The effect of cigarette smoke on Persistent Allergic Rhinitis patients (RAP) prevalence is increasing in Indonesia. Although the number of people who smoke is increasing yet  it has not received attention for examination. Objective: To analyze the relationship between cigarette smoking "side-stream" (SS) with the change in total quality of life (TQL) among patients with Persistent Allergic Rhinitis (PAR). Method: This study is a case-control design, in which 63 patients with moderate-severe RAP evidenced by allergy tests are divided into treatment groups (32) and control (31) randomly. RAP 32 patients were exposed to cigarette smoke (SS) from 5 cigarettes for 2 hours in a room. All respondents were asked to fill out questionnaires quality of life of Juniper's RQLQ. Results: KH total between treatment groups was not significantly different with control. KH total exposed to secondhand smoke every day significantly different. Discussion: Cigarette smoke described in patients with RAP does not lead to changes in the quality of life.


Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1801 ◽  
Author(s):  
Hanna Sikorska-Szaflik ◽  
Barbara Sozańska

Asthma and allergic rhinitis are the most common chronic childhood diseases with an increasing prevalence worldwide. There is an urgent need to look for methods of preventing allergic diseases from an early age. The relationship between vitamin D status and allergic diseases has been discussed in several studies recently. 25-hydroxyvitamin D (25(OH)D) is suggested to affect the development and/or severity of asthma and allergic rhinitis. Observational studies have seemed to confirm that vitamin D deficiency may contribute to an increase in allergy and asthma. Following interventional studies, however, have yielded ambiguous results. In this review, we describe recent findings regarding 25(OH)D impact on allergic diseases and provide a systematic analysis of the causes of great variability of the achieved results in different studies.


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