Prevalence and Risk Factors for Typical Signs and Symptoms of Toxoplasmosis in Children Born to at Risk Pregnant Women Attending Prenatal Care in Temeke District, Tanzania

Objective The process of detecting people at high risk of schizophrenia from a community sample is a major challenge for prevention of psychotic disorders. The aim of this paper is to describe early detection procedures that can be implemented in primary care settings. Methods A selected literature review is supplemented by experiences and data obtained during the Buckingham Integrated Mental Health Care Project. Results General medical practitioners have been favoured as the agents most likely to prove helpful in detecting the key risk factors that predict the onset of schizophrenic disorders, as well as in recognising the earliest signs and symptoms of these conditions. However, the practical problems of screening for multiple and subtle risk factors in general practice are substantial, and general practitioners (GPs) often have difficulty recognising the earliest signs of a psychotic episode. A range of strategies to assist GPs detect early signs of psychosis in their patients are considered. Conclusions It is feasible to implement primary care setting early detection procedures for people at risk of schizophrenia. Implementation is aided by the use of a brief screening questionnaire, training sessions and case supervision; and increased collaboration with mental health services and other community agencies.

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315. Prenatal Hepatitis C Viral (HCV) Screening Practices and HCV-Associated Fetal, Neonatal and Pregnancy Outcomes in a Large Regional Healthcare System

Open Forum Infectious Diseases ◽

10.1093/ofid/ofz360.388 ◽

2019 ◽

Vol 6 (Supplement_2) ◽

pp. S167-S167

Author(s):

Tripti Adhikari ◽

Rachel Scott ◽

Utsav Timalsina ◽

Ariunzaya Amgalan ◽

Shari L Sawney ◽

...

Keyword(s):

Risk Factors ◽

Prenatal Care ◽

Pregnant Women ◽

Behavioral Health ◽

Healthcare System ◽

Categorical Variables ◽

Opioid Use ◽

Screening Practices ◽

Hcv Screening ◽

In Pregnancy

Abstract Background Prevalence of HCV in pregnancy is 0.1–3.6%. AASLD and IDSA now recommend HCV screening in pregnancy although CDC, USPSTF, or ACOG still do not—though HCV can be perinatally transmitted and carries associated complications for the mother and fetus. Our study objectives were to analyze prenatal HCV screening practices at a large regional healthcare system and the prevalence of HCV-associated maternal and fetal/neonatal outcomes. Methods We performed a nested propensity score (PS) case–control study of pregnant women who tested HCV Ab+ in a cross-sectional study of women presenting for prenatal care at a large regional healthcare system from January 17 to December 18. We collected retrospective EHR data, including state of residency, HCV Ab, RNA, care engagement, HCV risk factors, comorbidities, maternal and fetal/neonatal morbidity, and neonatal HCV testing (when available). Mixed and generalized linear models were used to examine differences in continuous and categorical variables, respectively, between cases and controls Results 14,363 women were seen for prenatal care; 4,891 (34%) were HCV tested, 75 (1.5%) tested HCV Ab+. Demographic and comorbidity data are shown in Table 1. HCV Ab+ cases had more co-morbidities, including obesity, heart disease, opioid use, and behavioral health issues compared with the controls. HCV risk factors included IVDU (64%) and tattoos (24%) (Figure 1). Neither past/current pregnancy-related complications nor fetal or neonatal adverse events (Figure 2) were statistically significantly different except for cholestasis in HCV Ab+ cases (5.3 vs. 0%, P = 0.04). Conclusion Our study showed only one-third of pregnant women are currently HCV screened in our health system. Universal screening would likely increase the number of HCV-infected women identified. Early HCV detection, repeated testing, and behavioral health intervention of those at high-risk may decrease further horizontal and vertical transmission of HCV in pregnancy. Disclosures All authors: No reported disclosures.

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Risk Factors for premature birth in a hospital

Revista Latino-Americana de Enfermagem ◽

10.1590/1518-8345.0775.2750 ◽

2016 ◽

Vol 24 (0) ◽

Cited By ~ 7

Author(s):

Margarita E. Ahumada-Barrios ◽

German F. Alvarado

Keyword(s):

Risk Factors ◽

Prenatal Care ◽

Pregnant Women ◽

Premature Birth ◽

Bivariate Analysis ◽

Control Group ◽

Case Group ◽

Retrospective Case ◽

History Of ◽

Inadequate Prenatal Care

Abstract Objective: to determine the risk factors for premature birth. Methods: retrospective case-control study of 600 pregnant women assisted in a hospital, with 298 pregnant women in the case group (who gave birth prematurely <37 weeks) and 302 pregnant women who gave birth to a full-term newborn in the control group. Stata software version 12.2 was used. The Chi-square test was used in bivariate analysis and logistic regression was used in multivariate analysis, from which Odds Ratios (OR) and Confidence Intervals (CI) of 95% were derived. Results: risk factors associated with premature birth were current twin pregnancy (adjusted OR= 2.4; p= 0.02), inadequate prenatal care (< 6 controls) (adjusted OR= 3.2; p <0.001), absent prenatal care (adjusted OR= 3.0; p <0.001), history of premature birth (adjusted OR= 3.7; p <0.001) and preeclampsia (adjusted OR= 1.9; p= 0.005). Conclusion: history of premature birth, preeclampsia, not receiving prenatal care and receiving inadequate prenatal care were risk factors for premature birth.

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Alcohol use, pregnancy and associated risk factors: a pilot cross-sectional study of pregnant women attending antenatal care in an urban city

10.21203/rs.2.12608/v3 ◽

2019 ◽

Author(s):

Imelda K Moise

Keyword(s):

Risk Factors ◽

Alcohol Use ◽

Prenatal Care ◽

Pregnant Women ◽

Screening Tool ◽

Demographic Factors ◽

Continuous Variables ◽

Cross Sectional ◽

Urban City ◽

Associated Risk Factors

Abstract Background Alcohol consumption during pregnancy is associated with adverse pregnancy outcomes such as preventable alcohol-related developmental disability fetal alcohol syndrome. In Zambia, alcohol use and associated risk factors have not been investigated, and screening in prenatal care is nonexistent. This study determined individual correlates and the prevalence of alcohol use in pregnant women attending prenatal care at two health clinics in Lusaka, Zambia. Methods A study adopted a cross-sectional design and recruited 188 pregnant women after seeking their informed consent from July 19 to 31, 2017. Participants aged 18 or over completed the T-ACE (Tolerance, Annoyance, Cut Down and Eye Opener) screening tool and validated alcohol-screening questionnaires on self-reported alcohol use periconceptional and during conception period while at their regular prenatal visit. The T-ACE screening tool assessed the risk of alcohol dependence in four short questions. The questionnaires included demographic questions. Bivariate analyses were performed using the χ2 test for dichotomous variables and the t-test for continuous variables. Mixed-effects linear models were used to evaluate the effect of outcome variables with patient-level variables. Results About 40 (21.2%) pregnant women were identified by the T-ACE as at-risk for problem drinking during pregnancy. Except for regular prenatal care and distance, there was no difference in the demographic factors between pregnant women who scored <2 on the T-ACE and those that scored > 2 points (all p’s > 0.05). A small proportional of women at both clinics reported binge drinking during the periconceptional period (12.7% vs. 3.2%, p=0.003) and beyond periconception period. Excluding employed women, no significant relationships were observed between alcohol use and demographic factors. Conclusion These findings underscore the need for targeted screening and intervention for alcohol use in all pregnant women in Zambia.

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RISK FACTORS OF HIV-1 VERTICAL TRANSMISSION (VT) AND THE INFLUENCE OF ANTIRETROVIRAL THERAPY (ART) IN PREGNANCY OUTCOME

Revista do Instituto de Medicina Tropical de São Paulo ◽

10.1590/s0036-46652014000200008 ◽

2014 ◽

Vol 56 (2) ◽

pp. 133-138 ◽

Cited By ~ 12

Author(s):

Maria F.M. Barral ◽

Gisele R. de Oliveira ◽

Rubens C. Lobato ◽

Raul A. Mendoza-Sassi ◽

Ana M.b. Martínez ◽

...

Keyword(s):

Risk Factors ◽

Prenatal Care ◽

Pregnant Women ◽

Pregnancy Outcome ◽

Vertical Transmission ◽

First Trimester ◽

Antiretroviral Drugs ◽

Vertical Transmission Of Hiv ◽

Hiv 1 ◽

In Pregnancy

In the absence of intervention, the rate of vertical transmission of HIV can range from 15-45%. With the inclusion of antiretroviral drugs during pregnancy and the choice of delivery route this amounts to less than 2%. However ARV use during pregnancy has generated several questions regarding the adverse effects of the gestational and neonatal outcome. This study aims to analyze the risk factors for vertical transmission of HIV-1 seropositive pregnant women living in Rio Grande and the influence of the use of ARVs in pregnancy outcome. Among the 262 pregnant women studied the rate of vertical transmission of HIV was found to be 3.8%. Regarding the VT, there was a lower risk of transmission when antiretroviral drugs were used and prenatal care was conducted at the referral service. However, the use of ART did not influence the outcome of pregnancy. However, initiation of prenatal care after the first trimester had an influence on low birth weight, as well as performance of less than six visits increased the risk of prematurity. Therefore, the risk factors analyzed in this study appear to be related to the realization of inadequate pre-natal and maternal behavior.

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Risk factors associated to fetal death

Sao Paulo Medical Journal ◽

10.1590/s1516-31801998000600005 ◽

1998 ◽

Vol 116 (6) ◽

pp. 1852-1857 ◽

Cited By ~ 6

Author(s):

Márcia Maria Auxiliadora de Aquino ◽

José Guilherme Cecatti ◽

Coríntio Mariani Neto

Keyword(s):

Risk Factors ◽

Prenatal Care ◽

Pregnant Women ◽

Fetal Death ◽

Abruptio Placentae ◽

Factors Associated ◽

Gestation Age ◽

The Social ◽

Independent Variable ◽

Social Demographic

OBJECTIVE: The purpose of this study was to investigate risk factors associated to fetal death in a Brazilian population. DESIGN: A case control study. SETTING: The Hospital Maternidade Leonor Mendes de Barros in São Paulo. PARTICIPANTS:122 pregnant women with diagnosis of fetal death and gestation age of 20 or more weeks and 244 controls of pregnant women who delivered liveborns. VARIABLES STUDIED: The fetal death (dependent variable), independent variable (the social demographic factors, clinical and obstetrical history, prenatal care indicators and pathological conditions). RESULTS: The risk factors associated to fetal death were abruptio placentae, syphilis, few prenatal care visits, one or more previous stillbirths, hospitalization during pregnancy, diabetes, age above or equal to 25 years, hypertension during pregnancy, anemia and age below 20 years. CONCLUSIONS: Results of the current study might be useful to orientate a primary prevention health program, specially those concerning antenatal care.

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PREGNANCY - ASSOCIATED PLASMA PROTEIN-A AND PREDICTION OF PREECLAMPSIA AMONG ANTENATING PREGNANT WOMEN IN LAGOS, NIGERIA

International Journal of Medical Science and Diagnosis Research ◽

10.32553/ijmsdr.v5i6.817 ◽

2021 ◽

Vol 5 (6) ◽

Author(s):

Abidoye Gbadegesin ◽

Taiwo Kuye-Kuku ◽

Ishaq A. Adesanya ◽

Joy O. Agbara ◽

Yusuf A. Oshodi ◽

...

Keyword(s):

Risk Factors ◽

At Risk ◽

Pregnant Women ◽

Plasma Protein ◽

Protein A ◽

University Teaching ◽

Significant Difference ◽

Patients At Risk ◽

The Relationship ◽

Risk Of Preeclampsia

Background: Preclampsia is a leading cause of maternal morbidity and mortality which accounts for 5%-10% of deaths worldwide. Several studies have attempted to effectively predict preclampsia early in pregnancy. The effective method of detection and treatment are yet to be determined. Early identification of women at risk would enhance prompt monitoring and treatment of both mother and fetus. International Federation of Gynaecology and obstetrics FIGO recommends that the use of risk factors along with biomarkers would be beneficial in predicting the disease among pregnant women. Thus, the discovery of a sensitive and specific biomarker would reduce the unwanted effect of preeclampsia. Several biomarkers have been studied but efforts to find an effective one for the prediction of preeclampsia is still elusive. The study evaluated the relationship between pregnancy-associated plasma protein-A (P PPA) and preeclampsia as a biomarker in predicting preeclampsia. Objectives: To determine the relationship between the levels of pregnancy-associated plasma protein-A and the onset of pre-eclampsia among pregnant women with risk factors for preeclampsia and those without known risk factors (control). Materials and Methods: A prospective cohort study of consenting patients who presented at the maternity unit of Ifako-Ijaiye Mother and Child Centre between 11-15 weeks gestation with risk factors for preeclampsia (cases) and those without known risk factors for preeclampsia (controls). Blood samples were obtained and sent to Lagos State University Teaching Hospital Medical Research Laboratory for analysis of Pregnancy Associated Plasma Protein-A (PAPP-A). Results: No significant correlation was found between the onset of preeclampsia and the levels of Pregnancy Associated Plasma Protein-A in pregnant women with risk as well as those without risk factors who later on developed the disease. p>0.05. Among women without identifiable risk of preeclampsia, median Pregnancy Associated Plasma Protein-A was significantly higher in pregnant women who did not develop Preeclampsia compared to those who subsequently developed preeclampsia (p=0.004). There was a statistically significant difference in the median PAPP-A levels between patients at risk of preeclampsia (cases) compared with those without risk (controls). p<0.05. Conclusion: There was a significantly lower median level of PAPP-A among patients with risk factors for preeclampsia when compared with low-risk patients. Meanwhile, there is no significant correlation between the levels of PAPP-A and onset of preeclampsia among those who subsequently developed the disease in those at risk and those without.

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GAMBARAN KEJADIAN PRE EKLAMSIA PADA IBU HAMIL

Midwifery Journal Jurnal Kebidanan UM Mataram ◽

10.31764/mj.v6i1.1694 ◽

2021 ◽

Vol 6 (1) ◽

pp. 6

Author(s):

Evi Wahyuntari ◽

Pratika Wahyuhidaya

Keyword(s):

Risk Factors ◽

At Risk ◽

Pregnant Women ◽

Medical Record ◽

Gestational Hypertension ◽

Tertiary Education ◽

Chronic Hypertension ◽

Medical Record Data ◽

Work Area ◽

Record Data

Kelainan tekanan darah selama kehamilan seperti preeklampsia, hipertensi gestasional, dan chronic hipertensi terjadi pada 10% wanita hamil. Kelainan tekanan darah ini akan berefek pada morbiditas, ketidakmampuan ibu dan penyebab kamatian tertinggi pada ibu hamil. Penelitian ini bertujuan untuk mengetahui faktor yang berhubungan dengan pre eklamsia pada kehamilan Penelitian deskriptif Populasi dalam penelitian ini adalah seluruh ibu hamil baik yang mengalami Preeklampsia maupun yang tidak mengalami Preeklampsia dan melakukan pemerikasaan di RSKIA Sadewa diambil dari data rekam medik pada bulan Januari sampai bulan Nopember 2018 dengan jumlah 2862 ibu hamil. Kriteria Inklusi semua ibu hamil normal yang tidak mengalami Preeklampsia dan data yang ada di dalam rekam medis pasien yang terisi lengkap. Kriteri eksklusi data rekam medis yang tidak terisi lengkap atau tidak adanya data salah satu dari kriteria insklusi Hasil: gambaran faktor risiko preeklampsia di RSKIA Sadewa 31 (31%) responden rentang usia berisiko, 95 (95%) dengan pendidikan tinggi, 53 (53%) responden dengan paritas multigravida, 83 (93%) riwayat kesehatan tidak berisiko. Kesimpulan gambaran preeklampsia di RSKIA Sadewa sebagian besar responden yang mengalami preeklamsia tidak memiliki riwayat kesehatan yang berisiko. Saran dengan mengetahui karakteristik responden, maka kejadian preeklampsia dapat di minimalisir.Blood pressure abnormalities during pregnancy such as pre-eclampsia, gestational hypertension, and chronic hypertension occur in 10% of pregnant women. This blood pressure disorder will influence morbidity, maternal disability and the highest cause of death in pregnant women. This study aims to determine factors associated with pre-eclampsia in pregnancy. Descriptive research the population in this study were all pregnant women both experiencing pre-eclampsia and those not experiencing pre-eclampsia and conducting examinations in RSKIA Sadewa taken from medical record data from January to November 2018 with a total of 2862 pregnant women. Criteria for inclusion of all normal pregnant women without preeclampsia and the data contained in the complete medical records of patients. Criteria for exclusion of incomplete medical record data or absence of data from one of the inclusion criteria Results: description of pre-eclampsia risk factors in RSKIA Sadewa 31 (31%) respondents at-risk age range, 95 (95%) with tertiary education, 53 (53 %) respondents with multigravida parity, 83 (93%) medical history was not at risk. Conclusion Anaemia's description in the work area of Kalasan Public Health Center most of the respondents did not experience anaemia before. Suggestions by knowing the characteristics of respondents, then events can be minimized by doing early detection of risk factors

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Alcohol use, pregnancy and associated risk factors: a pilot cross-sectional study of pregnant women attending antenatal care in an urban city

10.21203/rs.2.12608/v2 ◽

2019 ◽

Author(s):

Imelda K Moise

Keyword(s):

Risk Factors ◽

Alcohol Use ◽

Prenatal Care ◽

Pregnant Women ◽

Demographic Factors ◽

Continuous Variables ◽

Cross Sectional ◽

Urban City ◽

Adverse Pregnancy ◽

Associated Risk Factors

Abstract Background Alcohol consumption during pregnancy is associated with adverse pregnancy outcomes such as preventable alcohol-related developmental disability fetal alcohol syndrome. In Zambia, alcohol use and associated risk factors have not been investigated, and screening in prenatal care is nonexistent. This study determined individual correlates and the prevalence of alcohol use in pregnant women attending prenatal care at two health clinics in Lusaka, Zambia. Methods A study adopted a cross-sectional design and recruited 188 pregnant women after seeking their informed consent from July 19 to 31, 2017. Participants aged 18 or over completed validated alcohol screening questionnaires on self-reported alcohol use periconceptional and during conception period while at their regular prenatal visit. The questionnaires included demographic questions. Bivariate analyses were performed using the χ2 test for dichotomous variables and the t-test for continuous variables. Mixed-effects linear models were used to evaluate the effect of outcome variables with patient-level variables. Results About 40 (21.2%) pregnant women were identified by the T-ACE as at-risk for problem drinking during pregnancy. Except for regular prenatal care and distance, there was no difference in the demographic factors between pregnant women who scored <2 on the T-ACE and those that scored > 2 points (all p’s > 0.05). A small proportional of women at both clinics reported binge drinking during the periconceptional period (12.7% vs. 3.2%, p=0.003) and beyond periconception period. Excluding employed women, no significant relationships were observed between alcohol use and demographic factors. Conclusion These findings underscore the need for targeted screening and intervention for alcohol use in all pregnant women in Zambia.

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Screening the risk factors for methamphetamine use in pregnant women not receiving prenatal care

Journal of Obstetrics and Gynaecology Research ◽

10.1111/jog.14901 ◽

2021 ◽

Author(s):

Piyanuch Saysukanun ◽

Kullathorn Thephamongkhol ◽

Pathamaporn Tiengladdawong ◽

Julaporn Pooliam ◽

Porndara Sae Chua ◽

...

Keyword(s):

Risk Factors ◽

Prenatal Care ◽

Pregnant Women ◽

Methamphetamine Use

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