Environmentally friendly analytical method to assess enantioselective behaviour of pharmaceuticals and pesticides in river waters

2021 ◽  
Vol 24 ◽  
pp. 100558
Author(s):  
Bruce Petrie ◽  
Dolores Camacho-Muñoz
Keyword(s):  
Analytical Method ◽  
Environmentally Friendly ◽  
River Waters

Development and Validation of a Green Analytical Method for the Determination of Norfloxacin in Raw Material by FTIR Spectrophotometry

2016 ◽  
Vol 99 (6) ◽  
pp. 1533-1536 ◽  
Author(s):  
Jéssica Sayuri Hisano Natori ◽  
Eliane Gandolpho Tótoli ◽  
Hérida Regina Nunes Salgado
Keyword(s):  
Urinary Tract ◽  
Organic Solvents ◽  
Analytical Method ◽  
Environmentally Friendly ◽  
Raw Material ◽  
Waste Generation ◽  
Ftir Spectrophotometry ◽  
Tract Infections ◽  
Development And Validation

Abstract Norfloxacin is a broad-spectrum antimicrobial agent, widely used in humans and animals for the treatment of urinary tract infections. It is a second-generation fluoroquinolone. Several analytical methods to analyze norfloxacin have been described in the literature. However, most of them are complex and require the use of large amounts of organic solvents. This paper describes the development and validation of a green analytical method for the determination of norfloxacin in raw material by FTIR spectrophotometry. This method does not require the use of organic solvents, minimizing waste generation in the process and its environmental impacts. The development of methods that promote the reduction, prevention, or elimination of waste generation has become highly attractive to the pharmaceutical industry because of the growing demand from civil society and government authorities for environmentally friendly products and services. The FTIR spectrophotometry method was validated according to International Conference on Harmonization guidelines, showing adequate linearity (r = 0.9936), precision, accuracy, and robustness. This validated method can be used as an environmentally friendly alternative for the quantification of norfloxacin in raw material in QC routine analysis.

An environmentally friendly method for the determination of polycyclic aromatic hydrocarbons in different soil typologies

2019 ◽  
Vol 16 (7) ◽  
pp. 517
Author(s):  
Flavia De Nicola ◽  
Estefanía Concha-Graña ◽  
Enrica Picariello ◽  
Valeria Memoli ◽  
Giulia Maisto ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbons ◽  
Human Health ◽  
Aromatic Hydrocarbons ◽  
Analytical Method ◽  
Solid Phase ◽  
Environmentally Friendly ◽  
Limit Of Quantification ◽  
Industrial Soil ◽  
Relative Standard ◽  
Polycyclic Aromatic

Environmental contextPolycyclic aromatic hydrocarbons (PAHs) are widespread organic pollutants that tend to accumulate in soil. We developed an environmentally friendly analytical method for PAHs to evaluate human health risks associated with their presence in soils. The method is feasible for the analysis of soils with widely varying PAH contamination levels, and is well suited to environmental monitoring studies of relevance to human health. AbstractA microwave-assisted extraction, with a dispersive solid-phase purification step followed by programmed temperature vaporisation–gas chromatography–tandem mass spectrometry, is proposed as an environmentally friendly, simple and cheap analytical method for polycyclic aromatic hydrocarbons (PAHs) in soil. Different extraction and clean-up operating variables were tested to achieve satisfactory analytical performances: trueness from 92 to 114%, limit of quantification (LOQ) from 0.4 to 2µgkg−1 for most PAHs and intermediate precision, calculated as relative standard deviation (RSD), below 10%. The method was validated using both Certified Reference Material and real soil samples collected at sites subjected to different human activities. PAH contents ranged from 0.11 (in holm oak forest soil) to 1mgkg−1 d.w. (in an industrial soil) according to the anthropic gradient. The soil PAH contents measured were used to estimate the risk to human health, which suggested the exposure to the PAHs in soil as a potential risk for human health, especially at the industrial site. The feasibility of the method for soils with different PAH contamination degrees makes it relevant in monitoring programs.

A green analytical method for the determination of Cu, Fe, Mn, and Zn in wheat flour using total reflection X-ray fluorescence

2018 ◽  
Vol 33 (7) ◽  
pp. 1264-1268 ◽  
Author(s):  
Ignacio Machado ◽  
Sebastián Mondutey ◽  
Natalia Pastorino ◽  
Valeria Arce ◽  
Mariela Pistón
Keyword(s):  
Sample Preparation ◽  
Wheat Flour ◽  
Analytical Method ◽  
Environmentally Friendly ◽  
Total Reflection ◽  
X Ray ◽  
Subsequent Determination ◽  
Environmentally Friendly Method

A simple, fast and environmentally friendly method for sample preparation and subsequent determination of minerals in wheat flour using TXRF.

scholarly journals Determination of carbamazepine and diazepam by SPE-HPLC-DAD in Belém River water, Curitiba-PR/Brazil

2018 ◽  
Vol 13 (2) ◽  
pp. 1 ◽  
Author(s):  
Beatriz Böger ◽  
Bianca Do Amaral ◽  
Priscila Lagner da Silveira Estevão ◽  
Ricardo Wagner ◽  
Patricio Guillermo Peralta-Zamora ◽  
...  
Keyword(s):  
Factorial Design ◽  
River Water ◽  
Psychotropic Drugs ◽  
Analytical Method ◽  
Psychosocial Care ◽  
Correlation Coefficients ◽  
River Pollution ◽  
River Waters ◽  
23 Factorial Design

This work sought to determine the two psychotropic drugs most commonly released by Psychosocial Care Centers (CAPS) into urban river waters (Belém sub-basin, Curitiba, PR, Brazil). A simple analytical method using SPE followed by a HPLC–DAD was developed and validated. Strata-X® cartridges were used to extract (carbamazepine) CZ and diazepam (DZ) from water and SPE conditions were optimized by 23 factorial design. The validated method was specific for target compounds; correlation coefficients were above 0.9998, recovery between 85.8 and 98.4% and precision below 6.60% (RSD, n=3). This method was successfully applied to analyze river samples and pollution hotspots were identified. The CZ and DZ concentrations found ranged from 0.670 to 0.856 µg L-1 and from LOQ to 0.763 µg L-1, respectively, and confirmed that drug consumption is directly related to river pollution in the studied region.

A simple and green analytical method for determination of copper(ii) in whisky and sugarcane spirit by diffuse reflectance spectroscopy

2016 ◽  
Vol 8 (8) ◽  
pp. 1867-1875 ◽  
Author(s):  
João Carlos de Souza ◽  
Helena Redigolo Pezza ◽  
Leonardo Pezza
Keyword(s):  
Analytical Method ◽  
Diffuse Reflectance ◽  
Diffuse Reflectance Spectroscopy ◽  
Environmentally Friendly ◽  
Reflectance Spectroscopy ◽  
Spot Test ◽  
Analytical Methodology ◽  
Determination Of Copper

In this paper we propose a new, fast, simple, economical, portable and environmentally friendly analytical methodology for the determination of copper(ii) ions in whisky and sugarcane spirit, using the combination of spot-test and diffuse reflectance spectroscopy.

Molecular mechanisms and potential applications of the intrinsic chemiluminescence produced from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes

2020 ◽  
Vol 6 (9) ◽  
pp. 2259-2274
Author(s):  
Li Mao ◽  
Hui-Ying Gao ◽  
Bo Shao ◽  
Chun-Hua Huang ◽  
Ben-Zhan Zhu
Keyword(s):  
Analytical Method ◽  
Advanced Oxidation Processes ◽  
Molecular Mechanisms ◽  
Degradation Kinetics ◽  
Environmentally Friendly ◽  
Advanced Oxidation ◽  
Oxidation Processes ◽  
Potential Applications

Unprecedented ˙OH-dependent intrinsic chemiluminescence (CL) can be produced during the AOPs-mediated degradation of highly toxic haloaromatics (XAr), and a new CL analytical method was developed to measure XAr and monitor their degradation kinetics.

scholarly journals An analytical method for uranium and investigation of 238U and 234U concentrations in river waters.

RADIOISOTOPES ◽  
1991 ◽  
Vol 40 (3) ◽  
pp. 122-125 ◽  
Author(s):  
Katsuaki KAMETANI ◽  
Toshiro MATSUMURA ◽  
Makoto ASADA
Keyword(s):  
Analytical Method ◽  
River Waters

Densitometric Identification of Primitive Erythroblasts After Reaction With Diaminobenzidine

1973 ◽  
Vol 31 ◽  
pp. 328-329
Author(s):  
John A. Trotter
Keyword(s):  
Red Blood Cells ◽  
Analytical Method ◽  
Blood Cells ◽  
Guinea Pigs ◽  
Specific Protein ◽  
Visual Examination ◽  
Hemoglobin Synthesis ◽  
Peroxidatic Activity ◽  
Small Density

Hemoglobin is the specific protein of red blood cells. Those cells in which hemoglobin synthesis is initiated are the earliest cells that can presently be considered to be committed to erythropoiesis. In order to identify such early cells electron microscopically, we have made use of the peroxidatic activity of hemoglobin by reacting the marrow of erythropoietically stimulated guinea pigs with diaminobenzidine (DAB). The reaction product appeared as a diffuse and amorphous electron opacity throughout the cytoplasm of reactive cells. The detection of small density increases of such a diffuse nature required an analytical method more sensitive and reliable than the visual examination of micrographs. A procedure was therefore devised for the evaluation of micrographs (negatives) with a densitometer (Weston Photographic Analyzer).

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