scholarly journals INFLUENCE OF YEAST-CONTAINING DIETS ON THE TOTAL FATTY ACIDS AND CHOLESTEROL CONTENT OF THE LIVERS OF INTACT AND PARTIALLY NEPHRECTOMIZED RATS

1938 ◽  
Vol 125 (2) ◽  
pp. 455-459
Author(s):  
J.C. Hortenstine ◽  
Alfred Chanutin ◽  
Stephan Ludewig
2018 ◽  
Vol 65 (4) ◽  
Author(s):  
Soumya Salas ◽  
Kajal Chakraborty ◽  
P.T. Sarada ◽  
P. Vijayagopal

Chicoreus ramosus(Linnaeus, 1758), the branched murex, a species of marine gastropod mollusc collected off the Gulf of Mannar on the south-eastern coast of India was studied for the nutritional composition. The edible portion of C. ramosus demonstrated protein content with balanced ratio of essential to non-essential amino acids (~0.94). The C20-C22 n-3 fatty acids, eicosapentaenoic acid and docosahexaenoic acid, were predominant in the edible part (15.8 and 17.2% total fatty acids, respectively). Considerably lesser cholesterol content (28.7 mg 100 g-1), greater hypocholesterolemic/hypercholesterolemic index (6.3) and lesser atherogenic (0.2), thrombogenicity (0.1) indices showed its importance as a cardioprotective and antithrombogenic diet. The presence of antioxidative microelement selenium (30.44 μg 100 g-1) along with ascorbic acid and tocopherol (45.5 and 55.8 μg 100 g-1, respectively) demonstrated the value of this foodstuff to impart antioxidative defense in the metabolic system. A lesser sodium/potassium (Na/K) proportion (0.64) in C. ramosus could be coupled with a diminished threat of developing hypertension and cardiovascular disease. The aggregate amount of calcium and phosphorus (136.1 mg 100 g-1) showed the beneficial effect of this species in facilitating the recruitment of osteoblasts and bone mineralisation process. The previously undescribed report with regard to nutritional composition of C. ramosusappropriately demonstrated this low-value gastropod species as a valuable depot of essential nutritional elements and as a health food for human consumption.


1952 ◽  
Vol 30 (6) ◽  
pp. 471-483
Author(s):  
Eldon M. Boyd ◽  
Mary L. Connell ◽  
H. D. McEwen

The albino rat with an inoculated Walker carcinoma 256 was considered to be a dual organism and the influence of the tumor component upon the lipid and water concentration of the host component was studied. The total lipid, neutral fat, total fatty acids, total cholesterol, ester cholesterol, free cholesterol, and phospholipid, estimated by oxidative micromethods, and the water content were determined in carcass, skeletal muscle, and testicle of the host component after 28 days of growth of the tumor in 14 dual organisms and the data compared with corresponding values from 12 control albino rats without tumors. In the host component, the following statistically significant changes in concentration were found: a decrease in the neutral fat content of carcass and skeletal muscle and in the water content of the testicle; an increase in the phospholipid content of carcass and skeletal muscle, in the free cholesterol content of carcass, skeletal muscle, and testicle, in the ester cholesterol content of testicle and in the water content of carcass and skeletal muscle with corresponding changes in the concentration of total cholesterol, total fatty acids, and total lipid. In each instance, these shifts in concentration were toward the level in the tumor component, so that the lipid composition and water content of these tissues of the host component became more like those of the tumor component, suggesting a metabolism directing influence of the tumor upon the host.


Antioxidants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1629
Author(s):  
Juhyun Shin ◽  
Min-Ho Song ◽  
Ji-Woo Yu ◽  
Eun-Young Ko ◽  
Xiaomin Shang ◽  
...  

The present study was aimed to investigate the composition and contents and the major lipophilic compounds, including the sterols, fatty acids, and tocols of shellfish species. Moreover, to explore the antitumor activity of these lipophilic constituents, their cytotoxicity potentials were determined against five different human cancer cells, including colon carcinoma (HCT116), epithelial melanoma (A2058), glioblastoma multiforme (T98G), lung carcinoma (A549), and adenocarcinoma (HeLa). The results show a significant variation in the contents and composition of lipophilic constituents among the studied species. The highest omega-3 (n-3) polyunsaturated fatty acids (PUFAs) were recorded from arrow squid and pacific oysters, accounting for 53.2% and 53.0% of their total fatty acids, respectively. However, the highest cholesterol content was also recorded in arrow squid (154.4 mg/100 g; 92.6% of total sterols). In contrast, in the Japanese littleneck, Yesso scallop, and common orient clam, cholesterol was just 17.1%, 18.3%, and 18.9% of total sterols, respectively, making them the richest source of non-cholesterol sterols (NCS). Lipids extracted from shellfish species showed ABTS+•- and DPPH•-scavenging activities. In the cytotoxicity analysis, lipids extracted from the Argentine red shrimp showed the highest cytotoxicity against glioblastoma multiforme T98G cells, with an IC50 value of 12.3 µg/mL. The composition and cytotoxicity data reported herein may help explore the nutritional and anticancer potentials of shellfish species.


1943 ◽  
Vol 77 (5) ◽  
pp. 473-486 ◽  
Author(s):  
A. W. Winkler ◽  
S. H. Durlacher ◽  
H. E. Hoff ◽  
E. B. Man

1. In the dog and monkey bilateral nephrectomy or ureteral ligation results in a marked, progressive increase of total fatty acids, of free and esterified cholesterol, of phospholipid, and of free fat of serum. 2. No such changes follow unilateral nephrectomy, splenectomy, or fasting. 3. The increase after bilateral nephrectomy is not inhibited by glucose administration. 4. A marked increase of the phospholipid and a less significant elevation in cholesterol content of the liver accompanies this increase of serum lipids after bilateral nephrectomy.


1958 ◽  
Vol 107 (1) ◽  
pp. 33-41 ◽  
Author(s):  
Robert A. Patnode ◽  
Paul C. Hudgins ◽  
Bernard W. Janicki

Guinea pigs given three subcutaneous injections of triton WR-1339, 300 mg./kg., at 3 day intervals develop an intense lipemia as evidenced by marked increases in serum phospholipide, free cholesterol, ester cholesterol, neutral fat, and total fatty acids. The total fatty acid content of the lung, liver, and spleen, however, remains unchanged. No qualitative change in the fatty acids of the lung and liver from treated animals could be detected by the methods used. The injection of triton was found to diminish slightly the cholesterol content of the adrenal glands. The implications of these findings are discussed in relation to an understanding of the mechanism involved in the therapeutic action of triton in experimental tuberculosis.


2011 ◽  
Vol 27 (3) ◽  
pp. 1201-1208 ◽  
Author(s):  
N. Zaharia ◽  
R. Salamon ◽  
C. Pascal ◽  
S. Salamon ◽  
R. Zaharia

The purpose of this paper is to detect any changes in fatty acid and cholesterol content of goat colostrum in the period of 0-72 hours after kidding. For that purpose, samples of colostrum from 16 goats, belonging to local populations in north-eastern Romania where collected. Samples were preserved by freezing and then subjected to chemical analysis. Preparation of solutions for fatty acids analysis was based on the principle of methylation, by combining alkaline methylation (NaOCH3/MeOH) with acid (BF3/MeOH). For cholesterol we used the principle of fat saponification, using potassium hydroxide, followed by filtration and separation of cholesterol with hexane. Detection of cholesterol and fatty acids content was performed by gas chromatography device. Caprinic acid (C10:0), myristic acid (C14:0), palmitic acid (C16: 0), stearic acid (C18:0) and oleic acid (C18:1) quantified more than 75% of the total fatty acids determined 72 hours after birth. Among short-medium-chain fatty acids, capronic acid (C6:0) was found in highest proportion (average concentration of 5.7% of total fatty acids), but at the same time, presented the most obvious oscillation range from 0 to 72 hours (6.56% at birth, 2.45% and 7.59% from 12 hours to 72 hours), with the differences between mean values being significant (p<0.05). In the case of polyunsaturated fatty acids, the ratio between omega 3 and omega 6 was 1/4.64 at kidding and 1/4.23 at 72 hours after birth, the differences being insignificant. In goat colostrum, the mean concentration of cholesterol was 9.43 mg per 100 g.


Author(s):  
Ikumi Umetani ◽  
Eshetu Janka ◽  
Michal Sposób ◽  
Chris J. Hulatt ◽  
Synne Kleiven ◽  
...  

AbstractBicarbonate was evaluated as an alternative carbon source for a green microalga, Tetradesmus wisconsinensis, isolated from Lake Norsjø in Norway. Photosynthesis, growth, and lipid production were studied using four inorganic carbon regimes: (1) aeration only, (2) 20 mM NaHCO3, (3) 5% (v/v) CO2 gas, and (4) combination of 20 mM NaHCO3 and 5% CO2. Variable chlorophyll a fluorescence analysis revealed that the bicarbonate treatment supported effective photosynthesis, while the CO2 treatment led to inefficient photosynthetic activity with a PSII maximum quantum yield as low as 0.31. Conversely, bicarbonate and CO2 treatments gave similar biomass and fatty acid production. The maximum growth rate, the final cell dry weight, and total fatty acids under the bicarbonate-only treatment were 0.33 (± 0.06) day−1, 673 (± 124) mg L−1 and 75 (± 5) mg g−1 dry biomass, respectively. The most abundant fatty acid components were α-linolenic acid and polyunsaturated fatty acids constituting 69% of the total fatty acids. The fatty acid profile eventuated in unsuitable biodiesel fuel properties such as high degree of unsaturation and low cetane number; however, it would be relevant for food and feed applications. We concluded that bicarbonate could give healthy growth and comparative product yields as CO2.


2009 ◽  
Vol 4 (10) ◽  
pp. 1934578X0900401 ◽  
Author(s):  
Christel Brunschwig ◽  
François Xavier Collard ◽  
Jean-Pierre Bianchini ◽  
Phila Raharivelomanana

In order to establish a chemical fingerprint of vanilla diversity, thirty samples of V. planifolia J. W. Moore and V. tahitensis G. Jackson cured beans from seven producing countries were examined for their aroma and fatty acid contents. Both fatty acid and aroma compositions were found to vary between vanilla species and origins. Vanillin was found in higher amounts in V. planifolia (1.7-3.6% of dry matter) than in V. tahitensis (1.0-2.0%), and anisyl compounds were found in lower amounts in V. planifolia (0.05%) than in V. tahitensis (1.4%-2.1%). Ten common and long chain monounsaturated fatty acids (LCFA) were identified and were found to be characteristic of the vanilla origin. LCFA derived from secondary metabolites have discriminating compositions as they reach 5.9% and 15.8% of total fatty acids, respectively in V. tahitensis and V. planifolia. This study highlights the role of the curing method as vanilla cured beans of two different species cultivated in the same country were found to have quite similar fatty acid compositions.


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