scholarly journals CHANGES IN LIPID CONTENT OF SERUM AND OF LIVER FOLLOWING BILATERAL RENAL ABLATION OR URETERAL LIGATION

1943 ◽  
Vol 77 (5) ◽  
pp. 473-486 ◽  
Author(s):  
A. W. Winkler ◽  
S. H. Durlacher ◽  
H. E. Hoff ◽  
E. B. Man

1. In the dog and monkey bilateral nephrectomy or ureteral ligation results in a marked, progressive increase of total fatty acids, of free and esterified cholesterol, of phospholipid, and of free fat of serum. 2. No such changes follow unilateral nephrectomy, splenectomy, or fasting. 3. The increase after bilateral nephrectomy is not inhibited by glucose administration. 4. A marked increase of the phospholipid and a less significant elevation in cholesterol content of the liver accompanies this increase of serum lipids after bilateral nephrectomy.

1973 ◽  
Vol 19 (4) ◽  
pp. 491-496 ◽  
Author(s):  
M. Gunasekaran ◽  
W. M. Hess ◽  
D. J. Weber

Pyrenochaeta terrestris, the onion pink root fungus, was grown on a reciprocal shaker in a synthetic medium which contained cellulose as the only carbon source. The mycelium was processed for lipid analysis and ultrastructural investigations after 8, 16, 24, and 32-day growth intervals.Hyphal cells contained membrane complexes. An electron-dense substance was present in large quantities on hyphal cell walls until after the 24-day period. As the cultures aged, organelles in some hyphal cells disintegrated and viable hyphal cells grew inside senescent cells in some cases. It was not possible to correlate positively lipid content observed at the ultrastructural level with the biochemical lipid analysis as a result of the relatively small amount of lipid observed in hyphal cells at the ultrastructural level.The lipid analysis indicated that the lipid content and mycelial weight reached a maximum at the 16-day period. The major fatty acids present were: C16:0, C18:0, C18:1, and C18:2. As aging occurred, the amount of unsaturation increased in the free fatty acids, the total fatty acids, and the fatty acids of the diglycerides and triglycerides. Only the fatty acids of the monoglycerides failed to increase in unsaturation. The sterol content increased slightly over the total growth period.


1970 ◽  
Vol 48 (15) ◽  
pp. 949-950 ◽  
Author(s):  
A. Marzo ◽  
P. Ghirardi ◽  
D. Sardini ◽  
B. D. Prandini ◽  
A. Albertini

2019 ◽  
Vol 53 (2) ◽  
pp. 38-45
Author(s):  
Irem Deniz ◽  
Zeliha Demirel ◽  
Esra Imamoglu ◽  
Meltem Conk Dalay

AbstractInternal illumination systems are being considered for use as an alternative light supply technique in microalgal products. The main goal of the study was to analyze the roles of different light wavelengths in internally illuminated airlift photobioreactors (PBRs) providing the light energy in an efficient way for the biomass production, lipid yield, and fatty acid composition of Amphora capitellata. The maximum chlorophyll-a concentration per unit biomass (2.62 ± 0.16 mg L−1) was obtained under red light, which was only 14% higher than under blue light in internally illuminated airlift PBR, whereas low chlorophyll-a content was found under white light. Maximum specific growth rate of 0.317 day−1, which corresponded to a doubling time of 2.185 days, was obtained under red light for A. capitellata. It was found that lipid content increased with decreasing growth rate for A. capitellata. Palmitic acid (C16:0) and palmitoleic acid (C16:1) were the principal fatty acids accounting for between 31%‐33% and 31%‐32% of total fatty acids, respectively. It is important to underline that red and blue light spectrum ranges contribute to improved biomass growth, whereas white light has the potential to support lipid content of diatoms.


2017 ◽  
Vol 42 (3) ◽  
Author(s):  
Zeliha Demirel ◽  
Esra Imamoglu ◽  
Meltem Conk Dalay

AbstractIntroduction:The main target of this study was to compare the effects of nitrogen limitation and light intensities on cell growth, lipid content and fatty acid profile ofMethods:F/2 medium and N-free F/2 medium were both tested at two different light intensities of 11 and 56 μEmResults:The presence of nitrogen led to more cells grown efficiently. Furthermore, the increase in chlorophyll content went parallel to the increase in dry weight. The most abundant saturated and monounsaturated fatty acids were pentadecanoic acid (C15:0) and palmitoleic acid (C16:1) which constituted 17%–42% and 15%–48% of total fatty acids for all growth conditions, respectively. It was recorded that palmitoleic acid was present at higher concentrations than palmitic acid.Discussion and conclusion:The noteworthy finding was that the lipid content increased with increasing the growth rate of


2018 ◽  
Vol 65 (4) ◽  
Author(s):  
Soumya Salas ◽  
Kajal Chakraborty ◽  
P.T. Sarada ◽  
P. Vijayagopal

Chicoreus ramosus(Linnaeus, 1758), the branched murex, a species of marine gastropod mollusc collected off the Gulf of Mannar on the south-eastern coast of India was studied for the nutritional composition. The edible portion of C. ramosus demonstrated protein content with balanced ratio of essential to non-essential amino acids (~0.94). The C20-C22 n-3 fatty acids, eicosapentaenoic acid and docosahexaenoic acid, were predominant in the edible part (15.8 and 17.2% total fatty acids, respectively). Considerably lesser cholesterol content (28.7 mg 100 g-1), greater hypocholesterolemic/hypercholesterolemic index (6.3) and lesser atherogenic (0.2), thrombogenicity (0.1) indices showed its importance as a cardioprotective and antithrombogenic diet. The presence of antioxidative microelement selenium (30.44 μg 100 g-1) along with ascorbic acid and tocopherol (45.5 and 55.8 μg 100 g-1, respectively) demonstrated the value of this foodstuff to impart antioxidative defense in the metabolic system. A lesser sodium/potassium (Na/K) proportion (0.64) in C. ramosus could be coupled with a diminished threat of developing hypertension and cardiovascular disease. The aggregate amount of calcium and phosphorus (136.1 mg 100 g-1) showed the beneficial effect of this species in facilitating the recruitment of osteoblasts and bone mineralisation process. The previously undescribed report with regard to nutritional composition of C. ramosusappropriately demonstrated this low-value gastropod species as a valuable depot of essential nutritional elements and as a health food for human consumption.


1952 ◽  
Vol 30 (6) ◽  
pp. 471-483
Author(s):  
Eldon M. Boyd ◽  
Mary L. Connell ◽  
H. D. McEwen

The albino rat with an inoculated Walker carcinoma 256 was considered to be a dual organism and the influence of the tumor component upon the lipid and water concentration of the host component was studied. The total lipid, neutral fat, total fatty acids, total cholesterol, ester cholesterol, free cholesterol, and phospholipid, estimated by oxidative micromethods, and the water content were determined in carcass, skeletal muscle, and testicle of the host component after 28 days of growth of the tumor in 14 dual organisms and the data compared with corresponding values from 12 control albino rats without tumors. In the host component, the following statistically significant changes in concentration were found: a decrease in the neutral fat content of carcass and skeletal muscle and in the water content of the testicle; an increase in the phospholipid content of carcass and skeletal muscle, in the free cholesterol content of carcass, skeletal muscle, and testicle, in the ester cholesterol content of testicle and in the water content of carcass and skeletal muscle with corresponding changes in the concentration of total cholesterol, total fatty acids, and total lipid. In each instance, these shifts in concentration were toward the level in the tumor component, so that the lipid composition and water content of these tissues of the host component became more like those of the tumor component, suggesting a metabolism directing influence of the tumor upon the host.


Antioxidants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1629
Author(s):  
Juhyun Shin ◽  
Min-Ho Song ◽  
Ji-Woo Yu ◽  
Eun-Young Ko ◽  
Xiaomin Shang ◽  
...  

The present study was aimed to investigate the composition and contents and the major lipophilic compounds, including the sterols, fatty acids, and tocols of shellfish species. Moreover, to explore the antitumor activity of these lipophilic constituents, their cytotoxicity potentials were determined against five different human cancer cells, including colon carcinoma (HCT116), epithelial melanoma (A2058), glioblastoma multiforme (T98G), lung carcinoma (A549), and adenocarcinoma (HeLa). The results show a significant variation in the contents and composition of lipophilic constituents among the studied species. The highest omega-3 (n-3) polyunsaturated fatty acids (PUFAs) were recorded from arrow squid and pacific oysters, accounting for 53.2% and 53.0% of their total fatty acids, respectively. However, the highest cholesterol content was also recorded in arrow squid (154.4 mg/100 g; 92.6% of total sterols). In contrast, in the Japanese littleneck, Yesso scallop, and common orient clam, cholesterol was just 17.1%, 18.3%, and 18.9% of total sterols, respectively, making them the richest source of non-cholesterol sterols (NCS). Lipids extracted from shellfish species showed ABTS+•- and DPPH•-scavenging activities. In the cytotoxicity analysis, lipids extracted from the Argentine red shrimp showed the highest cytotoxicity against glioblastoma multiforme T98G cells, with an IC50 value of 12.3 µg/mL. The composition and cytotoxicity data reported herein may help explore the nutritional and anticancer potentials of shellfish species.


1972 ◽  
Vol 18 (10) ◽  
pp. 1575-1576 ◽  
Author(s):  
M. Gunasekaran ◽  
W. M. Hess ◽  
D. J. Weber

The lipids from conidia of Aspergillus niger were extracted and identified. The polar lipid content was higher (54.3%) than the neutral lipid fraction (45.7%). The major fatty acids present were C16:0, C18:0, C18:1, and C18:2. The amount of unsaturation in total fatty acids (62%) was higher than the unsaturation in the polar lipids (35%). Freeze-etched replicas of dormant conidia revealed the presence of lipid bodies.


1958 ◽  
Vol 107 (1) ◽  
pp. 33-41 ◽  
Author(s):  
Robert A. Patnode ◽  
Paul C. Hudgins ◽  
Bernard W. Janicki

Guinea pigs given three subcutaneous injections of triton WR-1339, 300 mg./kg., at 3 day intervals develop an intense lipemia as evidenced by marked increases in serum phospholipide, free cholesterol, ester cholesterol, neutral fat, and total fatty acids. The total fatty acid content of the lung, liver, and spleen, however, remains unchanged. No qualitative change in the fatty acids of the lung and liver from treated animals could be detected by the methods used. The injection of triton was found to diminish slightly the cholesterol content of the adrenal glands. The implications of these findings are discussed in relation to an understanding of the mechanism involved in the therapeutic action of triton in experimental tuberculosis.


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