1277 Status and management of hypertension, in Greece; the role of the adoption of Mediterranean diet: the ATTICA study

Diet-based chemoprevention of cancer has emerged as an interesting approach to evade the disease or even target its early phases, reducing its incidence or slowing down tumor progression. In its basis in the essential role of angiogenesis for tumor growth and metastasis, angioprevention proposes the use of inhibitors of angiogenesis in cancer prevention. The anti-angiogenic potential exhibited by many natural compounds contained in many Mediterranean diet constituents makes this dietary pattern especially interesting as a source of chemopreventive agents, defined within the angioprevention strategy. In this review, we focus on natural bioactive compounds derived from the main foods included in the Mediterranean diet that display anti-angiogenic activity, as well as their possible use as angiopreventive agents.

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Mediterranean Diet for the Prevention of Gestational Diabetes in the Covid-19 Era: Implications of Il-6 In Diabesity

International Journal of Molecular Sciences ◽

10.3390/ijms22031213 ◽

2021 ◽

Vol 22 (3) ◽

pp. 1213

Author(s):

Anna Lucia Fedullo ◽

Antonio Schiattarella ◽

Maddalena Morlando ◽

Anna Raguzzini ◽

Elisabetta Toti ◽

...

Keyword(s):

Gestational Diabetes ◽

Mediterranean Diet ◽

Viral Infections ◽

High Body Mass Index ◽

Omega 3 ◽

C Reactive Protein ◽

Reactive Protein ◽

Gestational Weight ◽

Poor Outcomes

The aim of this review is to highlight the influence of the Mediterranean Diet (MedDiet) on Gestational Diabetes Mellitus (GDM) and Gestational Weight Gain (GWG) during the COVID-19 pandemic era and the specific role of interleukin (IL)-6 in diabesity. It is known that diabetes, high body mass index, high glycated hemoglobin and raised serum IL-6 levels are predictive of poor outcomes in coronavirus disease 2019 (COVID-19). The immunopathological mechanisms of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection include rising levels of several cytokines and in particular IL-6. The latter is associated with hyperglycemia and insulin resistance and could be useful for predicting the development of GDM. Rich in omega-3 polyunsaturated fatty acids, vitamins, and minerals, MedDiet improves the immune system and could modulate IL-6, C reactive protein and Nuclear Factor (NF)-κB. Moreover, polyphenols could modulate microbiota composition, inhibit the NF-κB pathway, lower IL-6, and upregulate antioxidant enzymes. Finally, adhering to the MedDiet prior to and during pregnancy could have a protective effect, reducing GWG and the risk of GDM, as well as improving the immune response to viral infections such as COVID-19.

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Factors Associated With Components of Arterial Pressure Among Older Individuals (the Multinational MEDIS Study): The Role of the Mediterranean Diet and Alcohol Consumption

Journal of Clinical Hypertension ◽

10.1111/jch.12370 ◽

2014 ◽

Vol 16 (9) ◽

pp. 645-651 ◽

Cited By ~ 8

Author(s):

Stefanos Tyrovolas ◽

Josep Maria Haro ◽

Evangelos Polychronopoulos ◽

Anargiros Mariolis ◽

Suzanne Piscopo ◽

...

Keyword(s):

Alcohol Consumption ◽

Arterial Pressure ◽

Mediterranean Diet ◽

Older Individuals ◽

Factors Associated ◽

The Mediterranean

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The role of the Mediterranean diet on sperm morphology in healthy men living in polluted area (EcoFoodFertility project)

Reproductive Toxicology ◽

10.1016/j.reprotox.2017.06.170 ◽

2017 ◽

Vol 72 ◽

pp. 45

Author(s):

Luigi Montano ◽

Giuseppe Porciello ◽

Anna Crispo ◽

Stefano Lorenzetti ◽

Salvatore Raimondo ◽

...

Keyword(s):

Mediterranean Diet ◽

Sperm Morphology ◽

Polluted Area ◽

Healthy Men ◽

The Mediterranean

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The role of Mediterranean diet in the course of subjective cognitive decline in the elderly population of Greece: results from a prospective cohort study

British Journal Of Nutrition ◽

10.1017/s0007114521005109 ◽

2021 ◽

pp. 1-29

Author(s):

George S. Vlachos ◽

Mary Yannakoulia ◽

Costas A. Anastasiou ◽

Mary H. Kosmidis ◽

Efthimios Dardiotis ◽

...

Keyword(s):

Cognitive Decline ◽

Mediterranean Diet ◽

The Elderly ◽

Protective Role ◽

Subjective Cognitive Decline ◽

Preventive Strategy ◽

Food Groups ◽

Medical Disorders ◽

The Mediterranean

Abstract Very few data are available regarding the association of adherence to the Mediterranean Diet (MeDi) with Subjective Cognitive Decline (SCD) evolution over time. A cohort of 939 cognitively normal individuals reporting self-experienced, persistent cognitive decline not attributed to neurological, psychiatric or medical disorders from the Hellenic Epidemiological Longitudinal Investigation of Aging and Diet (HELIAD study) was followed-up for a mean period of 3.10 years. We defined our SCD score as the number of reported SCD domains (memory, language, visuoperceptual and executive), ranging from 0 to 4. Dietary intake at baseline was assessed through a food frequency questionnaire; adherence to the MeDi pattern was evaluated through the Mediterranean Diet Score (MDS) that ranged from 0 to 55, with higher values indicating greater adherence to the MeDi. The mean SCD score in our cohort increased by 0.20 cognitive domains during follow-up. After adjustment for multiple potential confounders, we showed that an MDS higher by 10 points was associated with a 7% reduction in the progression of SCD within one year. In terms of food groups, every additional vegetable serving consumption per day was associated with a 2.3% reduction in SCD progression per year. Our results provide support to the notion that MeDi may have a protective role against the whole continuum of cognitive decline, starting at the first subjective complaints. This finding may strengthen the role of the MeDi as a population-wide, cost-effective preventive strategy targeting the modifiable risk factors for cognitive decline.

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