Current status and future priorities for rotavirus vaccine development, evaluation and implementation in developing countries1Prepared as a review for the Consensus Workshop on Rotavirus Vaccines for use in Developing Countries, Geneva, January 9–10, 1997. Sponsored by: The Global Programme for Vaccines, World Health Organization, The Children's Vaccine Initiative and the Centers for Disease Control and Prevention.1

Vaccine ◽  
1999 ◽  
Vol 17 (18) ◽  
pp. 2207-2222 ◽  
Author(s):  
Joseph S Bresee ◽  
Roger I Glass ◽  
Bernard Ivanoff ◽  
Jon R Gentsch
Keyword(s):  
Developing Countries ◽  
Disease Control ◽  
Vaccine Development ◽  
World Health ◽  
Current Status ◽  
Rotavirus Vaccine ◽  
Rotavirus Vaccines ◽  
Control And Prevention ◽  
Development Evaluation ◽  
Health Organization

Heterocycles in the Treatment of Neglected Tropical Diseases

2020 ◽  
Vol 27 ◽  
Author(s):  
Kush K. Maheshwari ◽  
Debasish Bandyopadhyay
Keyword(s):  
Developing Countries ◽  
Heterocyclic Compounds ◽  
Neglected Tropical Diseases ◽  
World Health ◽  
Current Status ◽  
Poor People ◽  
Tropical Diseases ◽  
Concise Review ◽  
The World ◽  
Health Organization

Background: Neglected tropical diseases (NTDs) affect a huge population of the world and majority of the victims belong to the poor community of the developing countries. Until now, the World Health Organization (WHO) has identified 20 tropical diseases as NTDs that must be addressed with high priority. However, many heterocyclic scaffolds have demonstrated potent therapeutic activity against several NTDs. Objective: There are three major objectives: (1) To discuss the causes, symptoms, and current status of all the 20 NTDs; (2) To explore the available heterocyclic drugs, and their mechanism of actions (if known) that are being used to treat NTDs; (3) To develop general awareness on NTDs among the medicinal/health research community and beyond. Methods: The 20 NTDs have been discussed according to their alphabetic orders along with the possible heterocyclic remedies. Current status of treatment with an emphasis on the heterocyclic drugs (commercially available and investigational) has been outlined. In addition, brief discussion of the impacts of NTDs on socio-economic condition is included. Results: NTDs are often difficult to diagnose and the problem is worsened by the unhealthy hygiene, improper awareness, and inadequate healthcare in the developing countries where these diseases primarily affect poor people. The statistics include duration of suffering, numbers affected, and access to healthcare and medication. The mechanism of actions of various heterocyclic drugs, if reported, have been briefly summarized. Conclusion: Scientists and pharmaceutical corporations should allocate more resources to reveal the in-depth mechanism of actions of many heterocyclic drugs that are currently being used for the treatment of NTDs. Analysis of current heterocyclic compounds and development of new medications can help in the fight to reduce/remove the devastating effects of NTDs. An opinion-based concise review has been presented. Based on available literature, this is the first effect to present all the 20 NTDs and related heterocyclic compounds under the same umbrella.

scholarly journals Immunizations in Athletes

2018 ◽  
Vol 10 (5) ◽  
pp. 427-433 ◽  
Author(s):  
Christopher D. Boston ◽  
Jennifer J. Bryan
Keyword(s):  
Disease Control ◽  
World Health Organization ◽  
Preventive Care ◽  
Vaccination Status ◽  
World Health ◽  
Team Physician ◽  
Level Of Evidence ◽  
Control And Prevention ◽  
Pubmed Search ◽  
Health Organization

Context: Immunizations are a cornerstone of preventive care and an important consideration for team physicians caring for athletes. Evidence Acquisition: A PubMed search was performed from August 2016 through May 2017 as well as a website review of the Centers for Disease Control and Prevention, World Health Organization, and Immunization Action Coalition. Study Design: Clinical review. Level of Evidence: Level 4. Results: By keeping abreast of diseases endemic to nations to which athletes may be traveling as well as the vaccination status of the athletes, team physicians can provide appropriate advice regarding immunization and prevention of disease. Conclusion: There are a host of regularly updated reliable websites to assist the team physician in these recommendations.

scholarly journals The effects of COVID-19 pandemic on the provision of urgent surgery: a perspective from the USA

2020 ◽  
Vol 2020 (4) ◽  
Author(s):  
Abhiman Cheeyandira
Keyword(s):  
Disease Control ◽  
Surgical Care ◽  
Lessons Learned ◽  
World Health ◽  
Urgent Surgery ◽  
The World ◽  
Control And Prevention ◽  
The Usa ◽  
Health Organization ◽  
Made In

Abstract Corona virus pandemic has affected all the 50 states in the USA. States such as NY, CA and WA being the most affected. According to the Centers for Disease Control and Prevention (CDC) website, as of 28 March 2020, the total number of cases in the USA is over 103 300 and number of deaths to 1668. In the coming weeks, COVID-19 rates are expected to begin skyrocketing and hit a peak in late April/May/June given lessons learned from China, Italy and others. COVID-19 has been declared a pandemic by the World Health Organization (WHO) as confirmed cases approach 575 444 patients with 26 654 deaths across over 160 countries, as of 28 March 2020. There is a lot of impact on management of the urgent and emergent cases. This article highlights the changes that are being made in delivering urgent and emergent surgical care during the pandemic.

Keeping the flu at bay: Methods for detecting and containing infectious disease

2009 ◽  
Vol 7 (4) ◽  
pp. 9
Author(s):  
Atresha Karra, JD ◽  
Emily Cornette, JD
Keyword(s):  
Infectious Disease ◽  
United States ◽  
Disease Control ◽  
The United States ◽  
Communicable Diseases ◽  
World Health ◽  
Reporting Requirements ◽  
The World ◽  
Control And Prevention ◽  
Health Organization

This article focuses on the existing methods for tracking and restricting the spread of communicable diseases, both within United States borders and across nations. It will first describe the roles played by the United States’ Centers for Disease Control and Prevention and the World Health Organization and will then explore how communicable diseases across the world are identified and monitored. This will be followed by a discussion of US and world reporting requirements and methods. Finally, the article will discuss the tactics used by the United States to control the spread of disease.

scholarly journals Rotavirus Vaccines for Infants in Developing Countries in Africa and Asia: Considerations from a World Health Organization–Sponsored Consultation

2009 ◽  
Vol 200 (s1) ◽  
pp. S63-S69 ◽  
Author(s):  
A. Duncan Steele ◽  
Manish Patel ◽  
Umesh D. Parashar ◽  
John C. Victor ◽  
Teresa Aguado ◽  
...  
Keyword(s):  
Developing Countries ◽  
World Health Organization ◽  
World Health ◽  
Rotavirus Vaccines ◽  
Health Organization

scholarly journals Outbreak column 21: Tuberculosis (TB): Still a nosocomial threat

2017 ◽  
Vol 19 (3) ◽  
pp. 144-150
Author(s):  
Evonne T Curran
Keyword(s):  
Disease Control ◽  
World Health Organization ◽  
Infection Prevention ◽  
World Health ◽  
Nosocomial Transmission ◽  
National Guidance ◽  
The World ◽  
Control And Prevention ◽  
Health Organization ◽  
The Uk

This outbreak column explores the epidemiology and infection prevention guidance on tuberculosis (TB) in the UK. The column finds that, at present, national guidance leaves UK hospitals ill-prepared to prevent nosocomial TB transmission. Reasons for this conclusion are as follows: (1) while TB is predominantly a disease that affects people with ‘social ills’, it has the potential to infect anyone who is sufficiently exposed; (2) nosocomial transmission is documented throughout history; (3) future nosocomial exposures may involve less treatable disease; and (4) current UK guidance is insufficient to prevent nosocomial transmission and is less than that advocated by the World Health Organization and the Centers for Disease Control and Prevention.

scholarly journals The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA Region: A Systematic Review

Pathogens ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 213 ◽  
Author(s):  
Al Mana ◽  
Yassine ◽  
Younes ◽  
Al-Mohannadi ◽  
Al-Sadeq ◽  
...  
Keyword(s):  
Web Of Science ◽  
Severe Disease ◽  
The United States ◽  
World Health ◽  
Current Status ◽  
Inclusion Criteria ◽  
Mena Region ◽  
Scientific Databases ◽  
Control And Prevention ◽  
Health Organization

Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), CMV infects people of all ages, and by the age of five, approximately one-third of children in the United States are infected. Although the infection is generally asymptomatic, it can cause severe disease in immunocompromised patients, transplant and transfusion recipients, as well as newborn neonates. The objective of this study is to systematically review published literature on CMV in the MENA region to estimate its incidence in the region and describe its epidemiological and clinical significance. The literature was searched through four scientific databases: PubMed, Scopus, Science Direct, and Web of Science. A total of 72 studies from 11 countries satisfied the inclusion criteria, covering a period from 1988–2019. The CMV IgG seroprevalence ranged from 8.7%–99.2% (SD = 38.95%). CMV incidence in these countries ranged between 1.22% and 77% in transplant and transfusion recipients, with an increase in incidence with advanced age. However, the incidence rate was unclear for congenital CMV due to the variability of the reporting. This review highlights the need for more robust and well-designed studies to better estimate CMV incidence in the MENA region, standardize diagnostic criteria, and consider prophylactic and pre-emptive treatments to limit the morbidity and mortality of the disease.

scholarly journals COVID-19—Orthodontic Care During and After the Pandemic: A Narrative Review

2020 ◽  
Vol 54 (4) ◽  
pp. 352-365
Author(s):  
Jitendra Sharan ◽  
Nameirakpam Ibemcha Chanu ◽  
Ashok Kumar Jena ◽  
Sivakumar Arunachalam ◽  
Prabhat Kumar Choudhary
Keyword(s):  
Infection Control ◽  
Disease Control ◽  
Disease Transmission ◽  
World Health ◽  
Presenting Symptoms ◽  
Language Restriction ◽  
Control And Prevention ◽  
Cross Transmission ◽  
Mode Of Transmission ◽  
Health Organization

Objectives: To provide comprehensive information regarding the implications of the coronavirus disease 2019 (COVID-19), mode of transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), and its effects on orthodontic care during the pandemic and post-pandemic outbreak of the disease, based on currently available literature and information. Materials and Methods: A comprehensive research for studies that focused on the COVID-19 pandemic and orthodontic care up to August 18, 2020, with no language restriction. The databases included PubMed, MEDLINE, Scopus, Google Scholar, and COVID-19 Open Research Dataset (CORD-19) 2020. The research was focused on presenting symptoms, disease transmission, infection control, orthodontic care, and financial implications affecting the delivery of orthodontic treatment. The research also included reports from major health policy regulatory bodies such as World Health Organization, Centers for Disease Control and Prevention, European Centre for Disease Control and Prevention, and major international dental and orthodontic societies and associations. The peer-reviewed publications and guidelines from the health regulatory authorities were given priority. Results: The latest information on the SARS-CoV-2 virus effects and orthodontic implications were arranged sequentially. The SARS-CoV-2 virus mode of transmission and its prevention were emphasized to keep the orthodontic and dental operatory safe for continuing practice. Conclusion: The COVID-19 outbreak has changed the way orthodontics is practiced. Strict infection control, near-zero aerosol production, and minimal touch dentistry are the keys to prevent contamination of orthodontic operatory. During the pandemic, only emergency orthodontic procedures could be extended to the orthodontic patient while adhering to all the regulatory guidelines. Fortunately, to date, there is no reported case of cross-transmission of the SARS-CoV-2 virus at the dental setup.

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