Comorbidity of affective disorders

2011 ◽  
Vol 26 (S2) ◽  
pp. 1714-1714
Author(s):  
M.J. Martín Calvo ◽  
L. Fernández Mayo ◽  
I. García del Castillo ◽  
R. Carmona Camacho ◽  
E. Serrano Drozdowskyj ◽  
...  

IntroductionThe studies about the comorbidity of major depressive disorder (MDD) and bipolar disorder (BD) have increased in the last years. The comorbidity with Axis I psychiatric disorders complicates the diagnosis, prognosis and treatment.ObjectivesTo analyze the prevalence of affective disorders associated with another Axis I psychiatric disorders to treat correctly from the beginning of the diagnosis and to improve the course of the disorder and the quality of life of these patientsMethodsThe subjects who participated in the study were diagnosed of bipolar I disorder, bipolar II disorder and MDD, according to DSM-IV-TR criteria. The sample (n = 114) was divided into three groups: MDD (n = 58), BD (n = 31) and a control group of healthy subjects (n = 25). The diagnosis and stability were assessed using the MINI International Neuropsyquiatric Interview and the Hamilton Depression Rating Scale (HDRS).ResultsBD had a significantly association with risk of suicide (38%), anxiety disorder (3.3%) and social phobia (12.9%). It was also reported a significant association between MDD and risk of suicide (71%), manic/hypomanic episodes (25.9%), anxiety disorder (37.9%), social phobia (25.9%) and generalized anxiety disorder (37.9%).ConclusionsIt is necessary for clinical practice an integrative model which takes into account the comorbidity of affective disorders to improve the response to treatment and the prognosis of these mental disorders

Author(s):  
Sivaji M. ◽  
Manickavasagam J. ◽  
Indumathi Sundaramurthi ◽  
Gopinathan S.

Background: Co morbidity between headache and psychiatric disorders is more prevalent in chronic headache patients. The bipolar disorders and anxiety disorders are predominant in migraine and TTH respectively. This co morbidities have a poor reflection and impact on quality and outcome of chronic headache patients and results in worst prognosis and poor response to medical treatment.Methods: The chronic headache patients especially migraine and tension type of headache were analyzed with following materials such as the structured psychiatric clinical interview with ICD-10 mental and behavioural disorder, DSM-5 criteria. HAM-A, HAM-D, BDI-2, BPRS, young mania rating scale, Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and panic disorder scale.Results: Various subsets of bipolar disorder and anxiety disorder were found as follows: 74% of migraineurs are associated with psychiatric disorders in which bipolar affective disorder 6%, depressive episode 48%, dysthymia 30%, GAD 10% and Panic disorder 6%. 52% of TTH are associated with psychiatric disorders as follows: major depressive episode 52%, GAD 30%, separation anxiety disorder 6%, PTSD 7%, OCD 3% and panic disorder 2%.Conclusions: From previous and future studies the headache can be identified according to subsets of headache with psychiatric disorders make easier to provide appropriate pharmacological and psychological treatment which may reduce the chronicity and intractability of headache.


2007 ◽  
Vol 36 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Peter J. Cooper ◽  
Catherine Gallop ◽  
Lucy Willetts ◽  
Cathy Creswell

AbstractAn examination was made of the extent to which maternal anxiety predicted response to treatment of children presenting with an anxiety disorder. In a sample of 55 children referred to a local NHS CAMH service for treatment of an anxiety disorder, systematic mental state interview assessment was made of both mothers and children, and both completed self-report questionnaires to assess aspects of anxiety, both immediately before the children received treatment and following treatment. Children of mothers with anxiety disorder overall responded less well to treatment than children of mothers with no anxiety disorder. There was some diagnostic specificity in this in that children of mothers with GAD did as well in treatment as children whose mothers had no anxiety, whereas children of mothers with social phobia did poorly. The outcome for children with anxiety appears to be related to the presence and nature of maternal anxiety. It would seem prudent that treatment of children with anxiety involves assessment of maternal anxiety. It is important to establish in systematic investigation whether treatment of maternal anxiety improves the outcome for child anxiety.


2001 ◽  
Vol 16 (2) ◽  
pp. 115-121 ◽  
Author(s):  
P.G. Gökalp ◽  
R. Tükel ◽  
D. Solmaz ◽  
T. Demir ◽  
E. Kiziltan ◽  
...  

The aim of this study is to investigate the clinical features and frequency and importance of related co-morbid disorders of social phobia in a clinical sample. Eighty-seven patients meeting DSM-III-R diagnostic criteria for social phobia were studied. All patients were assessed by using a semi-structured socio-demographic form, the Structured Clinical Interview for DSM-III-R, Manual for the Structured Clinical Interview for DSM-III-R Personality Disorders, Liebowitz Social Anxiety Scale, Hamilton Rating Scale for Depression and Hamilton Rating Scale for Anxiety. Sixty-eight (78.2%) of the group were male, 19 (21.8%) were female. The ages varied between 16–58 years, with a mean of 26.2 years (SD = 8.5). Fifty-one point seven percent of the subjects were assessed as having a co-morbid axis I disorder, of which 12.6% consisted of panic disorder and 10.3% agoraphobia. An additional axis II disorder had been found in 67.8% of the subjects, and 54.0% of them had been diagnosed as having avoidant personality disorder. The frequency of co-morbid disorders in our social phobic sample is lower than most of the studies in the literature. The interface between social phobia and avoidant personality disorder needs to be studied and discussed further.


2016 ◽  
Vol 20 (12) ◽  
pp. 1030-1038 ◽  
Author(s):  
Julia J. Rucklidge ◽  
Michelle Downs-Woolley ◽  
Mairin Taylor ◽  
Jason A. Brown ◽  
Sarah-Eve Harrow

Objective: To examine the rates of psychiatric comorbidities within a New Zealand sample of adults with ADHD compared with a community control group. Method: We merged six data sets to obtain a sample of 222 adults (158 ADHD, 64 controls). Comorbidities were assessed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders ( 4th ed. text rev. [ DSM-IV-TR]) Axis-I disorders. Results: Both groups were equivalent in IQ, socioeconomic status, gender, education, income levels, and age. Lifetime rates of psychiatric disorders were significantly higher in the ADHD group (83%) versus the control group (52%) with higher rates of major depressive disorder (MDD; 65% vs. 36%), social phobia (31% vs. 11%), substance abuse (26% vs. 8%), and alcohol abuse (32% vs. 14%). Within the ADHD group, other than a group difference in specific phobias, there were no gender differences. Conclusion: The findings are consistent with international research; adults with ADHD in New Zealand have higher rates of psychiatric disorders than the general population.


2003 ◽  
Vol 25 (2) ◽  
pp. 96-99 ◽  
Author(s):  
Gisele Gus Manfro ◽  
Luciano Isolan ◽  
Carolina Blaya ◽  
Sandra Maltz ◽  
Elizeth Heldt ◽  
...  

OBJECTIVE: The aim of this study was to evaluate the prevalence of traumas and the presence of childhood anxiety disorders in adult patients with social phobia and investigate their influence on the presentation of the disorder. METHODS: Twenty-four adult patients with social phobia were asked about the presence of trauma before the age of 16. The K-SADS-E and the DICA-P interviews were used to assess these patients regarding childhood anxiety disorders. RESULTS: Twelve (50%) patients reported a history of trauma before the age of 16. The presence of trauma did not influence the presentation of the disorder. Seventy-five percent of patients had a history of anxiety disorders in childhood. Patients with a history of at least 2 childhood anxiety disorders had an increased lifetime prevalence of major depression (10 vs. 3; p=.04) and family history of psychiatric disorders (13 vs. 6; p=.02). CONCLUSION: Anxiety disorder in childhood is associated with family history of psychiatric disorders. The presence of more than one diagnosis of anxiety disorder in childhood can be considered a risk factor for the development of depression in adult patients with social phobia.


2008 ◽  
Vol 36 (4) ◽  
pp. 379-389 ◽  
Author(s):  
Sarah A. Crawley ◽  
Rinad S. Beidas ◽  
Courtney L. Benjamin ◽  
Erin Martin ◽  
Philip C. Kendall

AbstractSocial phobia (SP) is characterized by a fear of one or more social or performance situations. Studies of comorbidity in SP youth find anxiety and affective disorders co-occurring. The present study examined children with primary SP and compared them to children with primary Separation Anxiety Disorder (SAD) or Generalized Anxiety Disorder (GAD) prior to treatment and in response to treatment. The groups differed significantly on self-, parent- and teacher-rated pretreatment measures. Additionally, the two groups showed differential treatment outcomes. When the SP youth with comorbid Affective Disorder were excluded in treatment outcome analyses, there were non significant differences, indicating that comorbid affective disorders likely contributed to differential treatment outcome. Results are discussed in terms of treatment recommendations for socially phobic youth.


Esculapio ◽  
2020 ◽  
Vol 16 (03, july 2020-Septmber 2020) ◽  
Author(s):  
Ameelia Sadaqat ◽  
Rabia Afzal ◽  
Nauman Mazhar ◽  
Naila Mairaj ◽  
Sadaf Malik ◽  
...  

Postpartum period along with pregnancy are considered to be emotionally susceptible periods. The association between emotional or psychiatric disorders and postpartum period has been documented since Hippocratic times. Hormonal changes have been implicated, along with multiple factors in the development of depression associated with postpartum period. Moreover, maternal depression can have devastating effects on neonate as well. This study explores an important area to assess the magnitude of problem in our setup, so that appropriate evaluation of mental health status and up-to-date management can be planned. Objective: To find out psychiatric morbidity among females presenting during postpartum period at a tertiary care hospital in Lahore. Methods: A cross-sectional study was done in Department of Obstetrics and Gynaecology of Central Park Teaching Hospital, Lahore. One Hundred women presenting in peripartum period were included in the study, using purposive sampling technique. After an informed consent participant's bio data was recorded. A structured proforma was used for psychiatric evaluation of the cases, which contained social and demographic details along with questions from Edinburgh postnatal depression scale. Psychiatric diagnosis was made according to DSM-5. Severity of illness was assessed using Hamilton rating scale for depression and Hamilton anxiety rating scale. Results: Postpartum follow up of 100 females revealed that 18% developed psychiatric morbidity. 13 had major depressive disorder and 5 females had anxiety disorder. There was no case of puerperal psychosis in any of the females postpartum in this study. Psychiatric morbidity and age group between 18-25 years (20.6%) showed significant correlation. Similarly, higher incidence of psychiatric morbidity was observed in women living in nuclear household (24.1%). Conclusion: Psychiatric morbidities are common among females during postpartum period. Major depression is the commonest one. Therefore assessment for depression should be included in routine obstetric follow-ups. Key Words: psychiatric morbidity, major depression, anxiety disorder, puerperal psychosis, postpartum females.


2019 ◽  
Vol 1 (2) ◽  
pp. 129-139
Author(s):  
Swaleha Mujawar ◽  
Suprakash Chaudhury ◽  
Daniel Saldanha

Background: Depression causes emotional and physical disturbances which impacts biological functions such as sleep, appetite, libido, and disinterest in sexual function. Since discussing sexual problems is considered a taboo, there is limited data available concerning the prevalence of sexual dysfunction in women with depression and its response to treatment. Aim: To assess the prevalence of sexual dysfunction in females with depressive disorder and the effects of treatment. Material and Methods: A total of 53 females with recurrent depression and age and sex matched normal control group were included in the study with their informed consent. All the subjects were assessed with the Hamilton Rating Scale for Depression (HAM-D), Arizona sexual experience scale (ASEX), and female sexual functioning index (FSFI), which were re-administered after 6 weeks of treatment. Results: There was a significant difference in the HAM-D, ASEX, and FSFI scores between index and control groups at baseline. There was a significant correlation between the scores of HAM-D, ASEX, and FSFI before treatment. The correlation between the HAM-D and ASEX scores after treatment was not significant. A significant correlation was found between the HAM-D scores and the scores of arousal, lubrication, orgasm, satisfaction, pain, total domains of FSFI after treatment. No correlation was found between the HAM-D scores and desire domain score of FSFI after treatment. Conclusion: Women with depression have a high prevalence of sexual dysfunction. A highly significant improvement in depression and sexual functioning was observed at the end of 6 weeks of antidepressant therapy. Despite the improvement in sexual dysfunctions, the individual domains of sexual functions were not comparable to the normal subjects at the end of 6 weeks suggesting the need for longer treatment.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
M. Musalek

In the last decades a large number of co-morbidity studies were published indicating a strong relationship between affective disorders and alcohol addiction. Patients with affective disorders suffer also from dependence disorders at about 6 times more often than the rest of the population. In 30 to 60 percent of patients with alcohol addiction also affective disorders are present. In this context authors emphasized that depressive states observed in the course of alcohol addiction may be reactions to problems occurring in the frame of dependence disorders. In contrast to that depressive mood disorders in general (and above all states of anxiety and increased tension often connected with depressive states) can also be considered as starting points of addictive behaviour. Furthermore alcohol itself may induce and catalyze depressive mood. Less attention has been paid to the role of manic or hypomanic states in dependence disorders. The few studies indicate an increased co-morbidity rate between bipolar II disorders and alcohol addiction. In a psychopathological study carried out on 200 alcohol addicts in the Anton Proksch Institute Vienna we focused on the co-morbidity with bipolar II as well as on the pathogenetic role of hypomanic states in the frame of constellations of conditions of alcohol dependence using among other scales and a standardized interview, the Hypomania Self Rating Scale (HSRS, Angst). Preliminary results underline a strong relationship between Bipolar II Disorders and Alcohol Addiction: hypomanic states induce high risk behaviours which may become responsible for relapse and increased alcohol consumption.


2011 ◽  
Vol 69 (2a) ◽  
pp. 176-179 ◽  
Author(s):  
Mariana Inés Ybarra ◽  
Arthur Kummer ◽  
Elizabeth Regina Comini Frota ◽  
José Teotônio de Oliveira ◽  
Rodrigo Santiago Gomez ◽  
...  

OBJECTIVE: To investigate the prevalence of psychiatric disorders in patients with myasthenia gravis (MG). METHOD: Forty-one patients with MG answered to a structured psychiatric interview (MINI-Plus). RESULTS: Eleven (26.1%) patients were diagnosed with a depressive disorder and 19 (46.3%) were diagnosed with an anxiety disorder. Patients with dysthymia were older (p=0.029) and had longer disease duration (p=0.006). Patients with social phobia also had longer disease duration (p=0.039). CONCLUSION: Psychiatric disorders in MG are common, especially depressive and anxiety disorders.


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